Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Adverse effects of long and straight multiwalled carbon nanotubes on cytoskeleton, nuclear lamina, and genome-wide transcriptome of primary human mesothelial cells
Reamon-Buettner, S.M.; Voepel, I.; Hiemisch, A.; Eckert, V.; Schaudien, D.; Ziemann, C.
Abstract
2019The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?
Pavan, C.; Delle Piane, M.; Gullo, M.; Filippi, F.; Fubini, B.; Hoet, P.; Horwell, C.J.; Huaux, F.; Lison, D.; Lo Giudice, C.; Martra, G.; Montfort, E.; Schins, R.; Sulpizi, M.; Wegner, K.; Wyart-Remy, M.; Ziemann, C.; Turci, F.
Zeitschriftenaufsatz
2019The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
Igl, Bernd-Wolfgang; Bitsch, Annette; Bringezu, Frank; Chang, Steffi; Dammann, Martina; Frötschl, Roland; Harm, Volker; Kellner, Rupert; Krzykalla, Volker; Lott, Jasmin; Nern, Marlies; Pfuhler, Stefan; Queisser, Nina; Schulz, Markus; Sutter, Andreas; Vaas, Lea; Vonk, Richardus; Zellner, Dietmar; Ziemann, Christina
Zeitschriftenaufsatz
2018Genotoxic and mutagenic potential of camphorquinone in L5178/TK(+/-) mouse lymphoma cells
Volk, Joachim; Ziemann, Christina; Leyhausen, Gabriele; Geurtsen, Werner
Zeitschriftenaufsatz
2018ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs - Comparative in vitro investigations
Ziemann, Christina; Reamon-Buettner, Stella Marie; Lison, Dominique; Bonner, J.C.; Brûle, Sybille van den; Simon, S.; Creutzenberg, Otto H.
Abstract
2018Platox in vitro and in vivo investigations (28-day inhalation) to generate valid toxicity data for risk assessment of carbon-based nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Oliveira, H.; Farcal, L.; Burla, S.
Abstract
2018The PLATOX project: Combining in vitro and in vivo investigations to generate valid toxicity data for risk assessment of graphene nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Schaudien, Dirk; Oliveira, Helena; Farcal, Lucian
Abstract
2018Untersuchungen zum zytotoxischen, gentoxischen und pro-inflammatorischen Potential von Graphen-Nanoplättchen in Rattenalveolarmakrophagen
Gripp, Tatjana
: Noll, Thomas (1. Gutachter); Ziemann, Christina (2. Gutachter)
Master Thesis
2017Additives for reducing the toxicity of respirable crystalline silica. SILIFE project
Monfort, E.; López-Lilao, A.; Escrig, A.; Ibanez, M.J.; Bonvicini, G.; Creutzenberg, O.; Ziemann, C.
Konferenzbeitrag
2017Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons
Lindner, Karina; Ströbele, Michael; Schlick, Sandra; Webering, Sina; Jenckel, André; Kopf, Johannes; Danov, Olga; Sewald, Katherina; Buj, Christian; Creutzenberg, Otto; Tillmann, Thomas; Pohlmann, Gerhard; Ernst, Heinrich; Ziemann, Christina; Hüttmann, Gereon; Heine, Holger; Bockhorn, Henning; Hansen, Tanja; König, Peter
Zeitschriftenaufsatz
2017Organosilane-based coating of quartz species from the traditional ceramics industry: Evidence of hazard reduction using in vitro and in vivo tests
Ziemann, Christina; Escrig, Alberto; Bonvicini, Giuliana; Ibañez, Maria Jesus; Monfort, Eliseo; Salomoni, Arturo; Creutzenberg, Otto H.
Zeitschriftenaufsatz
2016FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity
Wiesner, Jochen; Ziemann, Christina; Hintz, Martin; Reichenberg, Armin; Ortmann, Regina; Schlitzer, Martin; Fuhst, Rainer; Timmesfeld, Nina; Vilcinskas, Andreas; Jomaa, Hassan
Zeitschriftenaufsatz
2016In vitro and in vivo investigations to obtain validated toxicity data of graphene nanoplatelets
Farcal, L.; Ziemann, C.; Oliveira, H.; Burla, S.; Creutzenberg, O.
Abstract
2016The PHOENIX project: Nano-layered hybrid particles as flame retardant additives - toxicological in vitro investigations using lung-relevant cell models
Kodandaraman, G.; Rahmer, H.; Gomez, J.; Schaudien, D.; Brockmeyer, H.; Voepel, I.; Westendorf, A.; Creutzenberg, O.; Ziemann, C.
Abstract
2016Transcriptome signatures in human peritoneal mesothelial cells after exposure to multiwalled carbon nanotubes support a potential role of cellular senescence in mesothelioma development
Reamon-Buettner, S.M.; Hiemisch, A.; Voepel, I.; Ziemann, C.
Abstract
2015Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing
Guerard, M.; Baum, M.; Bitsch, Annette; Eisenbrand, G.; Elhajouji, A.; Epe, B.; Habermeyer, M.; Kaina, B.; Martus, H.J.; Pfuhler, S.; Schmitz, C.; Sutter, A.; Thomas, A.D.; Ziemann, Christina; Froetschl, R.
Zeitschriftenaufsatz
2015Influence of ELF-MF on the juvenile immune system of CD-1 mice
Müller, Meike; Ziemann, Christina; Tillmann, Thomas; Lewin, Geertje; Dasenbrock, Clemens
Abstract
2015Inhalation toxicity of carbon black depends on surface coating with polycyclic aromatic hydrocarbons
Hansen, Tanja; König, P.; Creutzenberg, Otto H.; Weinhold, K.; Schlick, S.; Tillmann, Thomas; Pohlmann, Gerhard; Kolling, Angelika; Ziemann, Christina; Kopf, Johannes; Ströbele, Michael; Bockhorn, H.; Danov, Olga; Sewald, Katherina; Müller, B.; Fehrenbach, Heinz
Abstract
2015New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk
Kirkland, David; Brock, Tom; Haddouk, Hasnaà; Hargeaves, Victoria; Lloyd, Melvyn; Mc Garry, Sarah; Proudlock, Raymond; Sarlang, Séverine; Sewald, Katherina; Sire, Guillaume; Sokolowski, Andrea; Ziemann, Christina
Zeitschriftenaufsatz
2015Selection of additives for reducing the toxicity of quartz in ceramic compositions
Escrig, A.; Ibanez, M.J.; Monfort, E.; Bonvicini, G.; Salomoni, A.; Creutzenberg, O.; Ziemann, C.
Zeitschriftenaufsatz
2015The SILICOAT project
Ziemann, Christina; Rahmer, Hartmut; Escrig Vidal, A.; Bonvicini, Giuliana; Ibanez Garcia, M.J.; Monfort Gimeno, E.; Creutzenberg, Otto H.
Konferenzbeitrag, Zeitschriftenaufsatz
2015The Silicoat project: In vitro and in vivo toxicity screening of quartz varieties from ceramics industry and approaches for an effective quartz surface coating
Creutzenberg, Otto H.; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Garcia, M.J.; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Ziemann, Christina
Abstract
2014CEFIC-LRI N1 project: Genotoxicity of a synthetic amorphous silica (SAS) in rats
Knebel, Jan; Ziemann, Christina; Creutzenberg, Otto H.
Abstract
2014Lack of marked cyto- and genotoxicity of cristobalite in devitrified (heated) alkaline earth silicate wools in short-term assays with cultured primary rat alveolar macrophages
Ziemann, Christina; Harrison, Paul T.C.; Bellmann, Bernd; Brown, Robert C.; Zoitos, Bruce K.; Class, Philippe
Zeitschriftenaufsatz
2014Multiwalled carbon nanotubes (MWCNT) induce DNA damage and cellular senescence in human peritoneal mesothelial LP9 cells
Reamon-Büttner, Stella Marie; Bellmann, Bernd; Hackbarth, Anja; Leonhardt, Albrecht; Niehof, Monika; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2014Prostaglandin D2-supplemented "functional eicosanoid testing and typing" assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease
Schäfer, Dirk; Dreßen, Peter; Brettner, Stefan; Rath, Norbert-Folke; Molderings, Gerhard J.; Jensen, Katrin; Ziemann, Christina
Zeitschriftenaufsatz
2014The SILICOAT project: In vitro and in vivo toxicity screening of quartz varieties from traditional ceramics industry and approaches for an effective quartz surface coating
Ziemann, Christina; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Ibañez, Maria Jesus; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Creutzenberg, Otto H.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Evaluation of immunohistochemical markers to detect the genotoxic mode of action of fine and ultrafine dusts in rat lungs
Rittinghausen, Susanne; Bellmann, Bernd; Creutzenberg, Otto; Ernst, Heinrich; Kolling, Angelika; Mangelsdorf, Inge; Kellner, Rupert; Beneke, Sascha; Ziemann, Christina
Zeitschriftenaufsatz
2013Evaluation of the gentoxic potential of different radiofrequency electromagnetic fields in MRC-5 cells and B6C3F1 mice
Ziemann, Christina; Tillmann, Thomas; Oertel, Antje; Brockmeyer, Heidrun; Murbach, M.; Capstick, M.; Kuster, N.; Dasenbrock, Clemens
Zeitschriftenaufsatz, Konferenzbeitrag
2013Human peritoneal mesothelial LP9 cells as a model system to determine the toxic and genotoxic potential of multiwalled carbon nanotubes (MWCNTs)
Reamon-Büttner, Stella Marie; Hackbarth, Anja; Voepel, Ines Rebeca; Brockmeyer, Heidrun; Bellmann, Bernd; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2013Human pleural mesothelial MeT-5A cells are a limited in vitro model for detection of potential asbestos-like genotoxic effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella Marie; Hackbarth, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013Multiwall carbon nanotubes exhibit a cytotoxic but not directly DNA-damaging potential in human LP9/TERT-1 peritoneal mesothelial cells
Hackbarth, Anja; Ziemann, Christina; Albrecht, L.; Steinberg, Pablo; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013No direct genotoxic potential of different radiofrequency electromagnetic fields in MRC-5 cells and B6C3F1 mice
Dasenbrock, Clemens; Tillmann, Thomas; Oertel, Antje; Brockmeyer, Heidrun; Murbach, M.; Capstick, M.; Kuster, N.; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxic effects of multiwall carbon nanotubes (MWCNT) in vivo and in vitro
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Ziemann, Christina; Leonhardt, A.; Heinrich, Uwe; Rittinghausen, Susanne
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxic effects of MWCNT in vivo and in vitro
Schlichting, Anja; Ziemann, Christina; Leonhardt, A.; Rittinghausen, Susanne; Schaudien, Dirk; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxicity profile of the GATA-3-specific DNAzyme hgd40 after inhalation exposure
Fuhst, R.; Runge, F.; Buschmann, J.; Ernst, H.; Praechter, C.; Hansen, T.; Erichsen, J. von; Turowska, A.; Hoymann, H.-G.; Müller, M.; Pohlmann, G.; Sewald, K.; Ziemann, C.; Schlüter, G.; Garn, H.
Zeitschriftenaufsatz
2012Human pleural mesothelial MeT-5A cells are a limited in vitro model system in determining potential asbestos-like effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella-Marie; Schlichting, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2012International round-robin study on the Ames fluctuation test
Reifferscheid, Georg; Maes, Hanna; Allner, Bernhard; Badurova, Jana; Belkin, Shimshon; Bluhm, Kerstin; Brauer, Frank; Bressling, Jana; Domeneghetti, Stefania; Elad, Tal; Flückiger-Isler, Sini; Grummt, Hans-Juergen; Gürtler, Rainer; Hecht, Adiel; Heringa, Minne; Hollert, Henner; Huber, Stefanie; Kramer, Maike; Ratte, Toni; Sauerborn-Klobucar, Roberta; Magdeburg, Axel; Sokolowski, Andrea; Soldan, Premysl; Smital, Tvrtko; Stalter, Daniel; Venier, Paola; Ziemann, Christina; Zipperle, Jürgen; Buchinger, Sebastian
Zeitschriftenaufsatz
2012Subacute and subchronic inhalation toxicity and dermal absorption of the nanoscaled zinc oxide Z-COTE HP1 in the rat
Creutzenberg, Otto H.; Ziemann, Christina; Hansen, Tanja; Ernst, Heinrich; Schaudien, Dirk; Schuchardt, Sven; Wiench, Karin; Bellmann, Bernd
Zeitschriftenaufsatz
2012Suspension of MWCNT for toxicological in vivo and in vitro studies
Heinrich, Uwe; Schlichting, Anja; Ziemann, Christina; Seyock, S.; Haase, D.; Leonhardt, A.; Bellmann, Bernd
Zeitschriftenaufsatz
2012Zinc oxide-nanosize does not change the toxicological profile
Wiench, Karin; Schulte, Sabine; Champ, Simon; Ma-Hock, Lan; Schneider, S.; Creutzenberg, Otto; Bellmann, Bernd; Ziemann, Christina; Monteiro-Riviere, Nancy; Revenzwaay, Bernnard; Landsiegel, Robert
Zeitschriftenaufsatz
2011Discrepancy between high clastogenic activity of trans-beta-nitrostyrene in vitro and lack in carcinogenicity might be related to inactivating metabolism and its high reactivity towards thiol groups
Ziemann, Christina; Apitius, Florian; Elend, Manfred; Baumgartner, S.; Volk, J.; Ritter, Detlef; Steinfelder, H.J.; Schuchardt, Sven
Konferenzbeitrag, Zeitschriftenaufsatz
2011Evaluation of reproductive/developmental and repeated dose (subchronic) toxicity and cytogenetic effects in rats of a roofing asphalt fume condensate by nose-only inhalation
Parker, C.M.; Schreiner, C.A.; Hallmark, N.; Kriech, A.J.; Osborn, L.V.; Fuhst, R.; Buschmann, J.; Ernst, H.; Hansen, T.; Pohlmann, G.; Preiß, A.; Ziemann, C.
Zeitschriftenaufsatz
2011Nitrostyrolderivate als potentielle neue Zytostatika in der Therapie von Leukämien?
Baumgartner, S.
: Ziemann, Christina (Betreuer); Reinhardt, Dirk (Betreuer)
Dissertation
2010Combinatorial effects of dental composite components on glutathione and ROS levels in oral epithelial cells
Fitz-Maier, H.; Volk, J.; Leyhausen, G.; Ziemann, C.; Geurtsen, W.
Abstract
2010Comparative mechanistical investigations on the genotoxic potential of nitrovinyluracil derivatives
Heinemann, D.; Ritter, D.; Kasper, C.; Eger, K.; Steinfelder, H.J.; Ziemann, C.
Abstract
2010Genotoxic potential of TEGDMA in oral epithelial cells
Volk, J.; Leyhausen, G.; Beckedorf, A.; Weitz, A.; Fitz-Maier, H.; Ziemann, C.; Geurtsen, W.
Zeitschriftenaufsatz, Konferenzbeitrag
2010Genotoxicity of 1-propanol. Is there a problem?
Licht, O.; Gerdes, H.; Ziemann, C.; Bitsch, A.; Mangelsdorf, I.
Abstract
2010Genotoxicity testing of sulfur dioxide (SO2) in a mouse bone marrow micronucleus test complemented with hematological endpoints
Ziemann, C.; Hansen, T.; Pohlmann, G.; Farrar, D.; Pohlenz-Michel, C.; Tillmann, T.; Mangelsdorf, I.
Zeitschriftenaufsatz
2010Quantification of local genotoxicity in rat lungs after 3 months of particle exposure by immunohistochemical detection of 8-OH-dG, gamma-H2AX, and poly(ADP-ribose)
Ziemann, C.; Bellmann, B.; Serwatzki, K.; Creutzenberg, O.; Ernst, H.; Kolling, A.; Beneke, S.; Rittinghausen, S.
Abstract
2009Absence of genotoxic potential of 902 MHz (GSM) and 1747 MHz (DCS) wireless communication signals: In vivo two-year bioassay in B6C3F1 mice
Ziemann, C.; Brockmeyer, H.; Reddy, S.B.; Prihoda, T.J.; Kuster, N.; Tillmann, T.; Dasenbrock, C.
Zeitschriftenaufsatz
2009Absence of genotoxicity of sulfur dioxide (SO2) in a bone marrow micronucleus test with NMRI mice, complemented with several hematological endpoints
Ziemann, C.; Hansen, T.; Pohlmann, G.; Farrar, D.; Pohlenz-Michel, C.; Mangelsdorf, I.
Abstract
2009Effects of heating on free crystalline silica content, appearance, and biological activity of devitrified alkaline earth insulation wools
Ziemann, C.; Class, P.; Bellmann, B.; Creutzenberg, O.; Brown, R.
Abstract
2009In vivo study with quartz-containing ceramic dusts: Inflammatory effects of two factory samples in lungs after intratracheal instillation in a 28-day study with rats
Creutzenberg, O.; Ziemann, C.; Hansen, T.; Ernst, H.; Jackson, P.; Cartlidge, D.; Brown, R.
Konferenzbeitrag
2009Nano- and microscaled titanium dioxide: Comparative study on the inflammatory and genotoxic effects after a 3-week inhalation in rats
Creutzenberg, O.; Pohlmann, G.; Hansen, T.; Rittinghausen, S.; Taugner, F.; Ziemann, C.
Konferenzbeitrag, Zeitschriftenaufsatz
2009Non-irradiated campherquinone induces DNA damage in human gingival fibroblasts
Volk, J.; Ziemann, C.; Leyhausen, G.; Geurtsen, W.
Zeitschriftenaufsatz
2009Quartz-containing ceramic dusts: In vitro screening of the cytotoxic, genotoxic and pro-inflammatory potential of 5 factory samples
Ziemann, C.; Jackson, P.; Brown, R.; Attik, G.; Rihn, B.H.; Creutzenberg, O.
Konferenzbeitrag
2009Vergleichende mechanistische Untersuchung zum gentoxischen Potential von Nitrovinyluracilderivaten
Heinemann, D.
: Kasper, C.; Ziemann, C.
Master Thesis
2008Genotoxicity of camphorquinone in HGF and mouse lymphoma cells
Volk, J.; Geurtsen, W.; Leyhausen, G; Beckedorf, A.; Rahmer, H.; Ziemann, C.
Abstract
2008In vitro and in vivo screening of the cytotoxic, pro-inflammatory and genotoxic potential of quartz-containing ceramic dusts
Ziemann, C.; Hansen, T.; Ernst, H.; Jackson, P.; Brown, R.; Creutzenberg, O.
Zeitschriftenaufsatz, Konferenzbeitrag
2008Measurement of genotoxicity in wastewater samples with the in vitro micronucleus test - results of a round-robin study in the context of standardisation according to ISO
Reifferscheid, G.; Ziemann, C.; Fieblinger, D.; Dill, F.; Gminski, R.; Grummt, H.-J.; Hafner, C.; Hollert, H.; Kunz, S.; Rodrigo, G.; Stopper, H.; Selke, D.
Zeitschriftenaufsatz
2008Quartz-containing ceramic dusts: In vitro screening of the cytotoxic and genotoxic potential of 5 factory samples
Ziemann, C.; Jackson, P.; Brown, R.; Attik, R.; Rihn, B.; Creutzenberg, O.
Konferenzbeitrag, Zeitschriftenaufsatz
2008Quartz-containing ceramic dusts: In vivo study on inflammatory effects of two factory samples in lungs after intratracheal instillation in a 28-day study with rats
Creutzenberg, O.; Ziemann, C.; Hansen, T.; Ernst, H.; Jackson, P.; Brown, R.
Konferenzbeitrag, Zeitschriftenaufsatz
2008Respirable crystalline silica in the ceramic industries
Monfort, E.; Ibanez, M.J.; Escrig, A.; Jackson, P.; Cartlidge, E.; Gorbunov, B.; Creutzenberg, O.; Ziemann, C.
Zeitschriftenaufsatz, Konferenzbeitrag
2008Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6
Abdul, J.Y.; Ritz, V.; Jakimenko, A.; Schmitz-Salue, C.; Siebert, H.; Awuah, D.; Kotthaus, A.; Kietzmann, T.; Ziemann, C.; Hirsch-Ernst, K.
Zeitschriftenaufsatz
2007Camphorquinone induces cytotoxic and genotoxic effects in primary human gingival fibroblasts
Volk, J.; Geurtsen, W.; Leyhausen, G; Günay, H.; Beckedorf, A.; Rahmer, H.; Ziemann, C.
Konferenzbeitrag
2007Generation of reactive oxygen species may participate in the clastogenic and mutagenic activity of trans-beta-nitrostvrene
Ziemann, C.; Rahmer, H.; Leyhausen, G; Steinfelder, H.J.; Volk, J.
Konferenzbeitrag, Zeitschriftenaufsatz
2007Importance of DNA-adduct formation and gene expression profiling of disease candidate genes in rats exposed to bitumen fumes
Halter, R.; Hansen, T.; Seidel, A.; Ziemann, C.; Borlak, J.
Zeitschriftenaufsatz
2007Transcriptional regulation of UDP-glucuronosyltransferase UGT2B1 expression in primary rat hepatocyte cultures
Ritz, V.; Lass, C.; Bamewitz, K.; Ziemann, C.; Rüdell, G.; Bauer, D.; Schmitz-Salue, C.; Hirsch-Ernst, K.I.
Konferenzbeitrag, Zeitschriftenaufsatz
2007Untersuchung von Abwasserproben auf Gentoxizität
Reifferscheid, G.; Selke, D.-M.; Ziemann, C.; Stopper, H.; Rodrigo, G.; Kunz, S.; Hollert, H.; Hafner, C.; Grummt, H.-J.; Gminski, R.; Fieblinger, D.; Dill, F.
Zeitschriftenaufsatz
2006The alkaline comet assay in vitro with primary rat alveolar macrophages
Ziemann, C.; Jackson, P.; Brown, R.; Creutzenberg, O.
Zeitschriftenaufsatz
2006Inflammatory effects of two quartz samples after intratracheal instillation in a 90-day study with rats
Creutzenberg, O.; Oberdörster, G.; Coogan, L.; Moll, W.F.; Hamilton, R.; Ziemann, C.; Muhle, H.
Zeitschriftenaufsatz
2006An intact C=C bond in the vinyl side chain is required for the pro-apoptotic effect of nitrostyrene and its derivatives
Steinfelder, H.J.; Quentin, I.; Leonhardt, U.; Krause, D.; Eger, K.; Ziemann, C.
Abstract
2006Involvement of topoisomerase II inhibition in clastogenic activity of trans-b-Nitrostyrene
Ziemann, C.; Krauß, S.; Brockmeyer, H.; Leonhardt, U.; Steinfelder, H.J.
Abstract
2006The role of Prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures
Ziemann, C.; Riecke, A.; Rüdell, G.; Oetjen, E.; Steinfelder, H.J.; Lass, C.; Kahl, G.F.; Hirsch-Ernst, K.I.
Zeitschriftenaufsatz
2006Update on COX-2 inhibitor patents with a focus on optimised formulation and therapeutic scope of drug combinations making use of COX-2 inhibitors
Puhlmann, U.; Schäfer, D.; Ziemann, C.
Zeitschriftenaufsatz
2005Complex clastogenic activity of trans-ß-nitrostyrene in vitro is related to cellular glutathione content
Ziemann, C.; Kaap, S.; Kleemann, I.; Steinfelder, H.J.
Konferenzbeitrag, Zeitschriftenaufsatz
2005Impact of the cyclooxygenase system on doxorubicin-induced functional multidrug resistance 1 overexpression and doxorubicin sensitivity in acute myeloid leukemic HL-60 cells
Puhlmann, U.; Ziemann, C.; Ruedell, G.; Vorwerk, H.; Schaefer, D.; Langebrake, C.; Schuermann, P.; Creutzig, U.; Reinhardt, D.
Zeitschriftenaufsatz
2004Contribution of the EP4-receptor, PKA and CREB to intrinsic mdr1b overexpression in rat hepatocyte cultures
Ziemann, C.; Rüdell, G.; Riecke, A.; Steinfelder, H.J.; Oetjen, E.; Hirsch-Ernst, K.I.
Zeitschriftenaufsatz, Konferenzbeitrag
2004Early DNA damage apparently con tributes to the pro-apoptotic effect of nitrostyrene derivatives in normal and BCL-XL over-expressing HL60 cells
Ziemann, C.; Kleemann, I.; Eger, K.; Steinfelder, H.J.
Konferenzbeitrag, Zeitschriftenaufsatz
2004The EP4 receptor and PKA-dependent modification of CRE binding proteins participate in intrinsic mdr1b gene activation in primary rat hepatocyte cultures
Ziemann, C.; Rüdell, G.; Riecke, A.; Steinfelder, H.J.; Oetjen, E.; Hirsch-Ernst, K.I.; Kahl, G.F.
Zeitschriftenaufsatz, Konferenzbeitrag
2004Modulation of doxorubicin induced MDR1 overexpression in human myeloid AML blasts by cyclooxygenase-inhibitors
Puhlmann, U.; Reinhardt, D.; Vorwerk, H.; Schäfer, D.; Ziemann, C.
Zeitschriftenaufsatz, Konferenzbeitrag
2004Opposite effects of low and high formaldehyde concentrations on DNA integrity, PGE2-synthesis, proliferation, and intermediate filament expression in human nasal epithelial cells
Schäfer, D.; Pods, R.; Ziemann, C.
Zeitschriftenaufsatz, Konferenzbeitrag
2004Prostaglandin receptor-mediated repression of phenobarbital- dependent induction of xenobiotic-metabolizing enzymes in primary rat hepatocyte cultures
Lass, C.; Heder, A.F.; Blume, S.; Ziemann, C.; Hirsch-Ernst, K.I.
Zeitschriftenaufsatz