Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2013A plant-produced H1N1 trimeric hemagglutinin protects mice from a lethal influenza virus challenge
Shoji, Y.; Jones, R.M.; Mett, V.; Chichester, J.A.; Musiychuk, K.; Sun, X.J.; Tumpey, T.M.; Green, B.J.; Shamloul, M.; Norikane, J.; Bi, H.; Hartman, C.E.; Bottone, C.; Stewart, M.; Streatfield, S.J.; Yusibov, V.
Zeitschriftenaufsatz
2013A plant-produced protective antigen vaccine confers protection in rabbits against a lethal aerosolized challenge with Bacillus anthracis Ames spores
Chichester, J.A.; Manceva, S.D.; Rhee, A.; Coffin, M.V.; Musiychuk, K.; Mett, V.; Shamloul, M.; Norikane, J.; Streatfield, S.J.; Yusibov, V.
Zeitschriftenaufsatz
2012Comparative characterization of the glycosylation profiles of an influenza hemagglutinin produced in plant and insect hosts
Zhang, S.; Sherwood, R.W.; Yang, Y.; Fish, T.; Chen, W.; Mccardle, J.A.; Jones, R.M.; Yusibov, V.; May, E.R.; Rose, J.K.C.; Thannhauser, T.W.
Zeitschriftenaufsatz
2012A cryohistological protocol for preparation of large plant tissue sections for screening intracellular fluorescent protein expression
Knapp, E.; Flores, R.; Scheiblin, D.; Modla, S.; Czymmek, K.; Yusibov, V.
Zeitschriftenaufsatz
2012Extraction, purification and characterization of the plant-produced HPV16 subunit vaccine candidate E7 GGG
Buyel, J.F.; Bautista, J.A.; Fischer, R.; Yusibov, V.M.
Zeitschriftenaufsatz
2012Formulation development of a plant-derived H1N1 influenza vaccine containing purified recombinant hemagglutinin antigen
Iyer, V.; Liyanage, M.R.; Shoji, Y.; Chichester, J.A.; Jones, R.M.; Yusibov, V.; Joshi, S.B.; Middaugh, C.R.
Zeitschriftenaufsatz
2012The human potential of a recombinant pandemic influenza vaccine produced in tobacco plants
Jul-Larsen, A.; Madhun, A.S.; Brokstad, K.A.; Montomoli, E.; Yusibov, V.; Cox, R.J.
Zeitschriftenaufsatz
2012Immunotoxic characterization of a nanoparticle-based inhalable influenza vaccine in murine and human precision cut lung slices
Neuhaus, Vanessa; Schwarz, Katharina; Koch, Wolfgang; Sewald, Katherina; Yusibov, V.; Braun, Armin
Abstract, Konferenzbeitrag
2012A plant-based system for rapid production of influenza vaccine antigens
Shoji, Y.; Farrance, C.E.; Bautista, J.; Bi, H.; Musiychuk, K.; Horsey, A.; Park, H.; Jaje, J.; Green, B.J.; Shamloul, M.; Sharma, S.; Chichester, J.A.; Mett, V.; Yusibov, V.
Zeitschriftenaufsatz
2012Production of non-glycosylated recombinant proteins in Nicotiana benthamiana plants by co-expressing bacterial PNGase F
Mamedov, T.; Ghosh, A.; Jones, R.M.; Mett, V.; Farrance, C.E.; Musiychuk, K.; Horsey, A.; Yusibov, V.
Zeitschriftenaufsatz
2012Safety and immunogenicity of a plant-produced recombinant hemagglutinin-based influenza vaccine (HAI-05) derived from A/Indonesia/05/2005 (H5N1) influenza virus
Chichester, J.A.; Jones, R.M.; Green, B.J.; Stow, M.; Miao, F.D.; Moonsammy, G.; Streatfield, S.J.; Yusibov, V.
Zeitschriftenaufsatz
2012Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development
Kushnir, N.; Streatfield, S.J.; Yusibov, V.
Zeitschriftenaufsatz
2011Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity
Farrance, C.E.; Chichester, J.A.; Musiychuk, K.; Shamloul, M.; Rhee, A.; Manceva, S.D.; Jones, R.M.; Mamedov, T.; Sharma, S.; Mett, V.; Streatfield, S.J.; Roeffen, W.; Vegte-Bolmer, M. van de; Sauerwein, R.W.; Wu, Y.M.; Muratova, O.; Miller, L.; Duffy, P.; Sinden, R.; Yusibov, V.
Zeitschriftenaufsatz, Konferenzbeitrag
2011Clinical development of plant-produced recombinant pharmaceuticals: Vaccines, antibodies and beyond
Yusibov, V.; Streatfield, S.J.; Kushnir, N.
Zeitschriftenaufsatz
2011Co-expression of multiple target proteins in plants from a tobacco mosaic virus vector using a combination of homologous and heterologous subgenomic promoters
Roy, G.; Weisburg, S.; Foy, K.; Rabindran, S.; Mett, V.; Yusibov, V.
Zeitschriftenaufsatz
2011Green algae Chlamydomonas reinhardtii possess endogenous sialylated N-glycans
Mamedov, T.; Yusibov, V.
Zeitschriftenaufsatz
2011An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses
Shoji, Y.; Chichester, J.A.; Palmer, G.A.; Farrance, C.E.; Stevens, R.; Stewart, M.; Goldschmidt, L.; Deyde, V.; Gubareva, L.; Klimov, A.; Mett, V.; Yusibov, V.
Zeitschriftenaufsatz
2011Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice
Madhun, A.S.; Haaheim, L.R.; Nøstbakken, J.K.; Ebensen, T.; Chichester, J.; Yusibov, V.; Guzman, C.A.; Cox, R.J.
Zeitschriftenaufsatz
2011A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge
Mett, V.; Chichester, J.A.; Stewart, M.L.; Musiychuk, K.; Bi, H.; Reifsnyder, C.J.; Hull, A.K.; Albrecht, M.T.; Goldman, S.; Baillie, L.W.J.; Yusibov, V.
Zeitschriftenaufsatz
2011Plant-based rapid production of recombinant subunit hemagglutinin vaccines targeting H1N1 and H5N1 influenza
Shoji, Y.; Chichester, J.A.; Jones, M.; Manceva, S.D.; Damon, E.; Mett, V.; Musiychuk, K.; Bi, H.; Farrance, C.; Shamloul, M.; Kushnir, N.; Sharma, S.; Yusibov, V.
Zeitschriftenaufsatz
2011A plant-produced Pfs230 vaccine candidate blocks transmission of Plasmodium falciparum
Farrance, C.E.; Rhee, A.; Jones, R.M.; Musiychuk, K.; Shamloul, M.; Sharma, S.; Mett, V.; Chichester, J.A.; Streatfield, S.J.; Roeffen, W.; Vegte-Bolmer, M. van de; Sauerwein, R.W.; Tsuboi, T.; Muratova, O.V.; Wu, Y.; Yusibov, V.
Zeitschriftenaufsatz
2010Formulation and pre-clinical evaluation of transmission blocking potential of plant-produced plasmodium falciparum sexual stage PFS25 and PFS230 vaccine candidates
Yusibov, V.; Farrance, C.E.; Chichester, J.A.; Jones, R.M.; Mett, V.; Musiychuk, K.; Shamloul, M.; Sharma, S.; Streatfield, S.; Sauerwein, R.W.; Roeffen, W.; Wu, Y.M.; Muratova, O.; Duffy, P.; Culpepper, J.
Abstract, Zeitschriftenaufsatz
2010Increased interferon-Gamma levels occur in the cerebral spinal fluid during the chronic phase of trypanosoma Brucei Brucei infection in cattle
Namayanja, M.; Flores, R.; Nanteza, A.; Nsadha, Z.; Eyanu, S.; Prichard, R.; Knapp, E.; Yusibov, V.; Lubega, G.W.
Abstract, Zeitschriftenaufsatz
2010A novel two-component Tobacco mosaic virus-based vector system for high-level expression of multiple therapeutic proteins including a human monoclonal antibody in plants
Roy, G.; Weisburg, S.; Rabindran, S.; Yusibov, V.
Zeitschriftenaufsatz
2010Severe organ and tissue abnormalities in ankole cattle experimentally infected with trypanosoma brucei brucei
Nanteza, A.; Nsadha, Z.; Eyanu, S.; Namayanja, M.; Flores, R.; Knapp, E.; Prichard, R.; Yusibov, V.; Lubega, G.W.
Abstract, Zeitschriftenaufsatz
2010Tubulin-based vaccine candidates to combat African animal trypanosomiasis
Knapp, E.; Goldschmidt, L.; Flores, R.; Kraemer, T.; Namayanja, M.; Nanteza, A.; Chichester, J.; Golovina, T.; Prichard, R.; Lubege, G.W.; Holtzman, D.; Yusibov, V.
Abstract, Zeitschriftenaufsatz
2009Antibodies to plant-produced plasmodium falciparum sexual stage protein PFS25 exhibit transmission blocking activity
Yusibov, V.; Chichester, J.A.; Farrance, C.E.; Mett, V.; Musiychuk, K.; Shamloul, M.; Sharma, S.; Streatfield, S.; Ugulava, N.; Sauerwein, R.W.; Roeffen, W.; Wu, Y.M.; Muratova, O.; Miller, L.H.; Holtzman, D.A.
Abstract
2009An E7-based therapeutic vaccine protects mice against HPV16 associated cancer
Venuti, A.; Massa, S.; Mett, V.; Vedova, L.D.; Paolini, F.; Franconi, R.; Yusibov, V.
Konferenzbeitrag, Zeitschriftenaufsatz
2009Immunogenicity of hemagglutinin from A/Bar-headed Goose/Qinghai/1A/05 and A/Anhui/1/05 strains of H5N1 influenza viruses produced in Nicotiana benthamiana plants
Shoji, Y.; Farrance, C.E.; Bi, H.; Shamloul, M.; Green, B.; Manceva, S.; Rhee, A.; Ugulava, N.; Roy, G.; Musiychuk, K.; Chichester, J.A.; Mett, V.; Yusibov, V.
Konferenzbeitrag, Zeitschriftenaufsatz
2009Immunogeniciy of tubulin-based subunit vaccine candidates which protect animals against challenge with trypanosoma brucei brucei
Knapp, E.; Namayanja, M.; Steger, K.; Flores, R.; Nanteza, A.; Chichester, J.; Lubega, G.; Prichard, R.; Holtzman, D.; Yusibov, V.
Abstract
2009Plant-derived hemagglutinin protects ferrets against challenge infection with the A/Indonesia/05/05 strain of avian influenza
Shoji, Y.; Bi, H.; Musiychuk, K.; Rhee, A.; Horsey, A.; Roy, G.; Green, B.; Shamloul, M.; Farrance, C.E.; Taggart, B.; Mytle, N.; Ugulava, N.; Rabindran, S.; Mett, V.; Chichester, J.A.; Yusibov, V.
Zeitschriftenaufsatz
2009Plant-produced human growth hormone shows biological activity in a rat model
Rabindran, S.; Stevenson, N.; Roy, G.; Fedorkin, O.; Skarjinskaia, M.; Ensley, B.; Yusibov, V.
Zeitschriftenaufsatz
2009A single component two-valent LcrV-F1 vaccine protects non-human primates against pneumonic plague
Chichester, J.A.; Musiychuk, K.; Farrance, C.E.; Mett, V.; Lyons, J.; Mett, V.; Yusibov, V.
Konferenzbeitrag, Zeitschriftenaufsatz
2009Transient protein expression in three Pisum sativum (green pea) varieties
Green, B.J.; Fujiki, M.; Mett, V.; Kaczmarczyk, J.; Shamloul, M.; Musiychuk, K.; Underkoffler, S.; Yusibov, V.; Mett, V.
Zeitschriftenaufsatz
2009Using plant cells as influenza vaccine substrates. Review
Chichester, J.A.; Haaheim, L.R.; Yusibov, V.
Zeitschriftenaufsatz
2008Development of a new cucumber mosaic virus-based plant expression vector with truncated 3a movement protein
Fujiki, M.; Kaczmarczyk, J.F.; Yusibov, V.; Rabindran, S.
Zeitschriftenaufsatz
2008Development of a plant expression vector based on cucumber mosaic virus with truncated 3a protein
Fujiki, M.; Kaczmarczyk, J.; Rabindran, S.; Yusibov, V.
Abstract, Konferenzbeitrag
2008Plant-expressed HA as a seasonal influenza vaccine candidate
Shoji, Y.; Chichester, J.A.; Bi, H.; Musiychuk, K.; Rosa, P. de la; Goldschmidt, L.; Horsey, A.; Ugulava, N.; Palmer, G.A.; Mett, V.; Yusibov, V.
Zeitschriftenaufsatz
2008A plant-produced influenza subunit vaccine protects ferrets against virus challenge
Mett, V.; Musiychuk, K.; Bi, H.; Farance, C.E.; Horsey, A.; Ugulava, N.; Shoji, Y.; Rosa, P. de la; Palmer, G.A.; Rabindran, S.; Streatfield, S.J.; Boyers, A.; Russell, M.; Mann, A.; Lambkin, R.; Oxford, J.S.; Schild, G.C.; Yusibov, V.
Zeitschriftenaufsatz
2008Plants as biofactories. Review
Mett, V.; Farrance, C.E.; Green, B.J.; Yusibov, V.
Zeitschriftenaufsatz
2008Production of recombinant proteins in clonal root cultures using episomal expression vectors
Skarjinskaia, M.; Karl, J.; Araujo, A.; Ruby, K.; Rabindran, S.; Streatfield, S.J.; Yusibov, V.
Zeitschriftenaufsatz
2008Recent progress in the development of plant derived vaccines
Yusibov, V.; Rabindran, S.
Zeitschriftenaufsatz
2008Tubulin-based subunit vaccine candidates show promise in animal studies
Knapp, E.; Flores, R.; Steger, K.; Lubega, G.; Nantezza, A.; Namayanja, M.; Prichard, R .; Holtzman, D.; Yusibov, V.
Abstract, Zeitschriftenaufsatz
2007Anti-cancer activity of plant-produced HPV16 E7 vaccine
Massa, S.; Franconi, R.; Brandi, R.; Muller, A.; Mett, V.; Yusibov, V.; Venuti, A.
Zeitschriftenaufsatz
2007Engineering and expression of the intracellular domain of insulinoma-associated tyrosine phosphatase (IA-2ic), a type 1 diabetes autoantigen, in plants
Mett, V.; Shamloul, A.M.; Hirai, H.; Zhou, Z.; Notkins, A.; Yusibov, V.
Zeitschriftenaufsatz
2007Immunogenicity of a subunit vaccine against Bacillus anthracis
Chichester, J.A.; Musiychuk, K.; Rosa, P. de la; Horsey, A.; Stevenson, N.; Ugulava, N.; Rabindran, S.; Palmer, G.A.; Mett, V.; Yusibov, V.
Konferenzbeitrag, Zeitschriftenaufsatz
2007A launch vector for the production of vaccine antigens in plants. Review
Musiychuk, K.; Stephenson, N.; Bi, H.; Farrance, C.E.; Orozovic, G.; Brodelius, M.; Brodelius, P.; Horsey, A.; Ugulava, N.; Shamloul, A.M.; Mett, V.; Rabindran, S.; Streatfield, S.J.; Yusibov, V.
Zeitschriftenaufsatz
2007A plant-produced plague vaccine candidate confers protection to monkeys
Mett, V.; Lyons, J.; Musiychuk, K.; Chichester, J.A.; Brasil, T.; Couch, R.; Sherwood, R.; Palmer, G.A.; Streatfield, S.J.; Yusibov, V.
Konferenzbeitrag, Zeitschriftenaufsatz
2007Plants as alternative systems for production of vaccines
Chichester, J.A.; Yusibov, V.
Zeitschriftenaufsatz
2007Plants as alternative systems for production oil vaccines
Chichester, J.A.; Yusibov, V.
Zeitschriftenaufsatz
2006The potential of plant virus vectors for vaccine production
Yusibov, V.; Rabindran, S.; Commandeur, U.; Twyman, R.M.; Fischer, R.
Zeitschriftenaufsatz
2005Clonal root technology (CRT) for target protein production
Skakjinskaia, M.V.; Karl, J.R.; Yusibov, V.M.
Abstract, Konferenzbeitrag, Zeitschriftenaufsatz
2005Human-derived, plant-produced monoclonal antibody for the treatment of anthrax
Hull, A.K.; Criscuolo, C.J.; Mett, V.; Groen, H.; Steeman, W.; Westra, H.; Chapman, G.; Legutki, B.; Baillie, L.; Yusibov, V.
Konferenzbeitrag, Zeitschriftenaufsatz
2005Inducible expression in plants by virus-mediated transgene activation
Hull, A.K.; Yusibov, V.; Mett, V.
Zeitschriftenaufsatz
2005Peptide-based candidate vaccine against respiratory syncytial virus
Yusibov, V.; Mett, V.; Mett, V.; Davidson, C.; Musiychuk, K.; Gilliam, S.; Farese, A.; MacVittie, T.; Mann, D.
Konferenzbeitrag, Zeitschriftenaufsatz
2005Plant-based technologies: Potential for vaccine development and delivery
Musiychuk, K.; Ugulava, N.; Men, V.; Yusibov, V.
Abstract
2004Plant viral expression vectors: History and developments
Yusibov, V.; Rabindran, S.
Aufsatz in Buch
2002Antibody expression in plants
Verch, T.; Lewandowski, D.; Schillberg, S.; Yusibov, V.; Koprowski, H.; Fischer, R.
Aufsatz in Buch