Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Ceramide synthase 5 deficiency aggravates dextran sodium sulfate-induced colitis and colon carcinogenesis and impairs T-cell activation
El-Hindi, K.; Brachtendorf, S.; Hartel, J.C.; Oertel, S.; Birod, K.; Trautmann, S.; Thomas, D.; Ulshöfer, T.; Weigert, A.; Utermöhlen, O.; Krönke, M.; Grösch, S.
Zeitschriftenaufsatz
2020In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o
Blum, L.; Gul, S.; Ulshöfer, T.; Henke, M.; Krieg, R.; Berneburg, I.; Thomas, D.; Trautmann, S.; Kurz, J.; Geyer, J.; Geisslinger, G.; Becker, K.; Parnham, M.J.; Schiffmann, S.
Zeitschriftenaufsatz
2020Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach
Ingelfinger, R.; Henke, M.; Roser, L.; Ulshöfer, T.; Calchera, A.; Singh, G.; Parnham, M.J.; Geisslinger, G.; Fürst, R.; Schmitt, I.; Schiffmann, S.
Zeitschriftenaufsatz
2019Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab
Mojtahed Poor, S.; Ulshöfer, T.; Gabriel, L.A.; Henke, M.; Köhm, M.; Behrens, F.; Geisslinger, G.; Parnham, M.J.; Burkhardt, H.; Schiffmann, S.
Zeitschriftenaufsatz
2019Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Kurz, J.; Barthelmes, J.; Blum, L.; Ulshöfer, T.; Wegner, M.-S.; Ferreiros, N.; Roser, L.; Geisslinger, G.; Grösch, S.; Schiffmann, S.
Zeitschriftenaufsatz
2019Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy
Feczkó, T.; Piiper, A.; Ansar, S.; Blixt, F.W.; Ashtikar, M.; Schiffmann, S.; Ulshöfer, T.; Parnham, M.J.; Harel, Y.; Israel, L.L.; Lellouche, J.-P.; Wacker, M.G.
Zeitschriftenaufsatz
2018The relevance of ceramides and their synthesizing enzymes for multiple sclerosis
Kurz, J.; Brunkhorst, R.; Foerch, C.; Blum, L.; Henke, M.; Gabriel, L.; Ulshöfer, T.; Ferreiros, N.; Parnham, M.J.; Geisslinger, G.; Schiffmann, S.
Zeitschriftenaufsatz
2016Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE
Tafferner, N.; Barthelmes, J.; Eberle, M.; Ulshöfer, T.; Henke, M.; deBruin, N.; Mayer, C.A.; Foerch, C.; Geisslinger, G.; Parnham, M.J.; Schiffmann, S.
Zeitschriftenaufsatz
2015Ceramide synthase6 / C16-ceramides mediate anti-inflammatory effects during the development of EAE and MS possibly by suppressing the migration and by deactivation of neutrophils: a new target for anti-inflammatory therapy in MS?
Mayer, C.A.; Männer de Bazo, A.; Foerch, C.; Eberle, M.; Ebel, P.; Barthelmes, J.; Tafferner, N.; Ferreiros, N.; Ulshöfer, T.; Henke, M.; Grösch, S.; Geisslinger, G.; Willecke, K.; Schiffmann, S.
Abstract
2015Different pathophysiological relevance of branched fatty acid metabolism in mice and men: alpha-methylacyl-CoA racemase regulates the T cell response only in experimental autoimmune encephalomyelitis but not in multiple sclerosis
Mayer, C.A.; Tafferner, N.; Barthelmes, J.; Eberle, M.; Ferreiros, N.; Ulshöfer, T.; Henke, M.; Bruin, N. de; Geisslinger, G.; Foerch, C.; Parnham, M.J.; Schiffmann, S.
Abstract
2015Drug release and targeting: The versatility of polymethacrylate nanoparticles for peroral administration revealed by using an optimized Iin Vitro-toolbox
Beyer, Susanne; Moosmann, Aline; Kahnt, Astrid S.; Ulshöfer, Thomas; Parnham, Michael J.; Ferreirós, Nerea; Wagner, Sylvia; Wacker, Matthias G.
Zeitschriftenaufsatz
2015Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils
Eberle, M.; Ebel, P.; Mayer, C.A.; Barthelmes, J.; Tafferner, N.; Ferreiros, N.; Ulshöfer, T.; Henke, M.; Foerch, C.; Männer de Bazo, A.; Grösch, S.; Geisslinger, G.; Willecke, K.; Schiffmann, S.
Zeitschriftenaufsatz
2015Nanocarriers for photodynamic therapy - rational formulation design and medium-scale manufacture
Villa Nova, M.; Janas, C.; Schmidt, M.; Ulshoefer, T.; Gräfe, S.; Schiffmann, S.; Bruin, N. de; Wiehe, A.; Albrecht, V.; Parnham, M.J.; Bruschi, M.L.; Wacker, M.G.
Zeitschriftenaufsatz
2014Nano-LC-MS/MS for the quantitation of prostanoids in immune cells
Thomas, D.; Suo, J.; Ulshöfer, T.; Jordan, H.; Bruin, N. de; Scholich, K.; Geisslinger, G.; Ferreirós, N.
Zeitschriftenaufsatz