Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Cancer-induced inflammation and inflammation-induced cancer in colon: A role for S1P lyase
Schwiebs, A.; Herrero San Juan, M.; Schmidt, K.G.; Wiercinska, E.; Anlauf, M.; Ottenlinger, F.; Thomas, D.; Elwakeel, E.; Weigert, A.; Farin, H.F.; Bonig, H.; Scholich, K.; Geisslinger, G.; Pfeilschifter, J.M.; Radeke, H.H.
Zeitschriftenaufsatz
2019Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation
Maric, J.; Ravindran, A.; Mazzurana, L.; Acker, A. van; Rao, A.; Kokkinou, E.; Ekoff, M.; Thomas, D.; Fauland, A.; Nilsson, G.; Wheelock, C.E.; Dahlen, S.-E.; Ferreiros, N.; Geisslinger, G.; Friberg, D.; Heinemann, A.; Konya, V.; Mjösberg, J.
Zeitschriftenaufsatz
2019A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients with Dementia
Gurke, R.; Etyemez, S.; Prvulovic, D.; Thomas, D.; Fleck, S.C.; Reif, A.; Geisslinger, G.; Lötsch, J.
Zeitschriftenaufsatz
2019Determination of endocannabinoids and endocannabinoid-like substances in human K3EDTA plasma - LC-MS/MS method validation and pre-analytical characteristics
Gurke, R.; Thomas, D.; Schreiber, Y.; Schäfer, S.M.G.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2019Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation
Bärnthaler, T.; Jandl, K.; Sill, H.; Uhl, B.; Schreiber, Y.; Grill, M.; Thomas, D.; Schicho, R.; Marsche, G.; Frank, S.; Heinemann, A.; Schuligoi, R.
Zeitschriftenaufsatz
2019Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice
Möser, C.V.; Möller, M.; Fleck, S.C.; Thomas, D.; Geisslinger, G.; Niederberger, E.
Zeitschriftenaufsatz
2019The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated
Bazarganipour, S.; Hausmann, J.; Oertel, S.; El-Hindi, K.; Brachtendorf, S.; Blumenstein, I.; Kubesch, A.; Sprinzl, K.; Birod, K.; Hahnefeld, L.; Trautmann, S.; Thomas, D.; Herrmann, E.; Geisslinger, G.; Schiffmann, S.; Grösch, S.
Zeitschriftenaufsatz
2019Omega-3 and -6 fatty acid plasma levels are not associated with liver cirrhosis-associated systemic inflammation
Schwarzkopf, K.M.; Queck, A.; Thomas, D.; Angioni, C.; Cai, C.; Freygang, Y.; Rüschenbaum, S.; Geisslinger, G.; Zeuzem, S.; Welsch, C.; Lange, C.M.
Zeitschriftenaufsatz
2019Selective Inactivation of Cancer Drugs by SAMHD1 Provides a Molecular Rationale for Therapeutic Stratification in AML
Schneider, C.; Oellerich, T.; Knecht, K.M.; Thomas, D.; Buzovetsky, O.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Geisslinger, G.; Keppler, O.T.; Xiong, Y.; Cinatl, J.
Abstract
2019Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML
Oellerich, T.; Schneider, C.; Thomas, D.; Knecht, K.M.; Buzovetsky, O.; Kaderali, L.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Rothenburger, T.; Mohr, S.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Michaelis, M.; Ferreiros, N.; Geisslinger, G.; Xiong, Y.; Keppler, O.T.; Cinatl, J.
Zeitschriftenaufsatz
2019Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation
Weigert, A.; Knethen, A. von; Thomas, D.; Faria, I.; Namgaladze, D.; Zezina, E.; Fuhrmann, D.; Petcherski, A.; Meyer zu Heringdorf, D.; Radeke, H.H.; Brüne, B.
Zeitschriftenaufsatz
2019Targeted lipidomics reveal derangement of ceramides in major depression and bipolar disorder
Brunkhorst-Kanaan, N.; Klatt-Schreiner, K.; Hackel, J.; Schröter, K.; Trautmann, S.; Hahnefeld, L.; Wicker, S.; Reif, A.; Thomas, D.; Geisslinger, G.; Kittel-Schneider, S.; Tegeder, I.
Zeitschriftenaufsatz
2019Thromboxane-Induced α-CGRP Release from Peripheral Neurons Is an Essential Positive Feedback Loop in Capsaicin-Induced Neurogenic Inflammation
Tarighi, N.; Menger, D.; Pierre, S.; Kornstädt, L.; Thomas, D.; Ferreiros, N.; Nüsing, R.M.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2019A validated LC-MS/MS method for the determination of homocysteic acid in biological samples
Gurke, R.; Schmidt, D.; Thomas, D.; Fleck, S.C.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
201820-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S.
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2018Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
Pleli, T.; Mondorf, A.; Ferreiros, N.; Thomas, D.; Dvorak, K.; Biondi, R.M.; Heringdorf, D.M.; Zeuzem, S.; Geisslinger, G.; Zimmermann, H.; Waidmann, O.; Piiper, A.
Zeitschriftenaufsatz
2018Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy
Brachtendorf, S.; Wanger, R.A.; Birod, K.; Thomas, D.; Trautmann, S.; Wegner, M.-S.; Fuhrmann, D.C.; Brüne, B.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2018The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain
Zimmer, B.; Angioni, C.; Osthues, T.; Toewe, A.; Thomas, D.; Pierre, S.C.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2018Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
Hitzel, J.; Lee, E.; Zhang, Y.; Bibli, S.I.; Li, X.; Zukunft, S.; Pflüger, B.; Hu, J.; Schürmann, C.; Vasconez, A.E.; Oo, J.A.; Kratzer, A.; Kumar, S.; Rezende, F.; Josipovic, I.; Thomas, D.; Giral, H.; Schreiber, Y.; Geisslinger, G.; Fork, C.; Yang, X.; Sigala, F.; Romanoski, C.E.; Kroll, J.; Jo, H.; Landmesser, U.; Lusis, A.J.; Namgaladze, D.; Fleming, I.; Leisegang, M.S.; Zhu, J.; Brandes, R.P.
Zeitschriftenaufsatz
2017CD200 selectively upregulates prostaglandin E2 and D2 synthesis in LPS-treated bone marrow-derived macrophages
Kern, K.; Pierre, S.; Schreiber, Y.; Angioni, C.; Thomas, D.; Ferreirós, N.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2017Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice
Oertel, S.; Scholich, K.; Weigert, A.; Thomas, D.; Schmetzer, J.; Trautmann, S.; Wegner, M.S.; Radeke, H.H.; Filmann, N.; Brüne, B.; Geisslinger, G.; Tegeder, I.; Grösch, S.
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2017GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation
Pierre, S.; Linke, B.; Suo, J.; Tarighi, N.; Turco, D. del; Thomas, D.; Ferreiros, N.; Stegner, D.; Frölich, S.; Sisignano, M.; Santos, S.M. dos; Debruin, N.; Nüsing, R.M.; Deller, T.; Nieswandt, B.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2017Machine-learned data structures of lipid marker serum concentrations in multiple sclerosis patients differ from those in healthy subjects
Lötsch, J.; Thrun, M.; Lerch, F.; Brunkhorst, R.; Schiffmann, S.; Thomas, D.; Tegder, I.; Geisslinger, G.; Ultsch, A.
Zeitschriftenaufsatz
2017R-flurbiprofen traps prostaglandins within cells by inhibition of multidrug resistance-associated protein-4
Wobst, I.; Ebert, L.; Birod, K.; Wegner, M.-S.; Hoffmann, M.; Thomas, D.; Angioni, C.; Parnham, M.J.; Steinhilber, D.; Tegeder, I.; Geisslinger, G.; Grösch, S.
Zeitschriftenaufsatz
2017The role of PGE2 in alveolar epithelial and lung microvascular endothelial crosstalk
Bärnthaler, T.; Maric, J.; Platzer, W.; Konya, V.; Theiler, A.; Hasenöhrl, C.; Gottschalk, B.; Trautmann, S.; Schreiber, Y.; Graier, W.F.; Schicho, R.; Marsche, G.; Olschewski, A.; Thomas, D.; Schuligoi, R.; Heinemann, A.
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2017SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia
Schneider, C.; Oellerich, T.; Baldauf, H.-M.; Schwarz, S.-M.; Thomas, D.; Flick, R.; Bohnenberger, H.; Kaderali, L.; Stegmann, L.; Cremer, A.; Martin, M.; Lohmeyer, J.; Michaelis, M.; Hornung, V.; Schliemann, C.; Berdel, W.E.; Hartmann, W.; Wardelmann, E.; Comoglio, F.; Hansmann, M.L.; Yakunin, A.F.; Geisslinger, G.; Ströbel, P.; Ferreiros, N.; Serve, H.; Keppler, O.T.; Cinatl, J.
Zeitschriftenaufsatz
2017Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction
Schwalm, S.; Beyer, S.; Frey, H.; Haceni, R.; Grammatikos, G.; Thomas, D.; Geisslinger, G.; Schaefer, L.; Huwiler, A.; Pfeilschifter, J.
Zeitschriftenaufsatz
2017Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients
Koch, A.; Grammatikos, G.; Trautmann, S.; Schreiber, Y.; Thomas, D.; Bruns, F.; Pfeilschifter, J.; Badenhoop, K.; Penna-Martinez, M.
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2016Comparability: Manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015
Williams, D.J.; Archer, R.; Archibald, P.; Bantounas, I.; Baptista, R.; Barker, R.; Barry, J.; Bietrix, F.; Blair, N.; Braybrook, J.; Campbell, J.; Canham, M.; Chandra, A.; Foldes, G.; Gilmanshin, R.; Girard, M.; Gorjup, E.; Hewitt, Z.; Hourd, P.; Hyllner, J.; Jesson, H.; Kee, J.; Kerby, J.; Kotsopoulou, N.; Kowalski, S.; Leidel, C.; Marshall, D.; Masi, L.; McCall, M.; McCann, C.; Medcalf, N.; Moore, H.; Ozawa, H.; Pan, D.; Parmar, M.; Plant, A.L.; Reinwald, Y.; Sebastian, S.; Stacey, G.; Thomas, R.J.; Thomas, D.; Thurman-Newell, J.; Turner, M.; Vitillio, L.; Wall, I.; Wilson, A.; Wolfrum, J.; Yang, Y.; Zimmerman, H.
Zeitschriftenaufsatz
2016High-throughput analysis of global DNA methylation using methyl-sensitive digestion
Shiratori, H.; Feinweber, C.; Knothe, C.; Lötsch, J.; Thomas, D.; Geisslinger, G.; Parnham, M.J.; Resch, E.
Zeitschriftenaufsatz
2016PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells
Josipovic, I.; Fork, C.; Preussner, J.; Prior, K.-K.; Iloska, D.; Vasconez, A.E.; Labocha, S.; Angioni, C.; Thomas, D.; Ferreirós, N.; Looso, M.; Pullamsetti, S.S.; Geisslinger, G.; Steinhilber, D.; Brandes, R.P.; Leisegang, M.S.
Zeitschriftenaufsatz
2015An injectable elastin-based gene delivery platform for dose-dependent modulation of angiogenesis and inflammation for critical limb ischemia
Dash, Biraja C.; Thomas, Dilip; Monaghan, Michael; Carroll, Oliver; Chen, Xizhe; Woodhouse, Kimberly; O'Brien, Timothy; Pandit, Abhay
Zeitschriftenaufsatz
2015Quantitation of endogenous nucleoside triphosphates and nucleosides in human cells by liquid chromatography tandem mass spectrometry
Thomas, D.; Herold, N.; Keppler, O.T.; Geisslinger, G.; Ferreirós, N.
Zeitschriftenaufsatz
2014Claritas™ - a unique and robust endpoint technology for silicon drie processes with open area down to 0.05%
Ansell, O.; Barnett, R.; Haase, T.; Xie, L.; Vargo, S.; Thomas, D.
Konferenzbeitrag
2014Nano-LC-MS/MS for the quantitation of prostanoids in immune cells
Thomas, D.; Suo, J.; Ulshöfer, T.; Jordan, H.; Bruin, N. de; Scholich, K.; Geisslinger, G.; Ferreirós, N.
Zeitschriftenaufsatz
2014Phosphodiesterase 2A Localized in the Spinal Cord Contributes to Inflammatory Pain Processing
Kallenborn-Gerhard, W.; Lu, R.; Bothe, A.; Thomas, D.; Schlaudraff, J.; Lorenz, J.E.; Lippold, N.; Real, C.I.; Ferreirós, N.; Geisslinger, G.; Turco, D. Del; Schmidtko, A.
Zeitschriftenaufsatz
2013Nano-LC–MS/MS for the quantitation of ceramides in mice cerebrospinal fluid using minimal sample volume
Thomas, D.; Eberle, M.; Schiffmann, S.; Zhang, D.; Geisslinger, G.; Ferreiros, N.
Zeitschriftenaufsatz
2013PleatLab. A pleat scale simulation environment for filtration simulation
Cheng, L.; Kirsch, R.; Wiegmann, A.; Gervais, P.-C.; Bardin-Monnier, N.; Thomas, D.
Konferenzbeitrag
2012Magnetisation transfer effects of Q2TIPS pulses in ASL
Vita, E. de; Günther, M.; Golay, X.; Thomas, D.L.
Zeitschriftenaufsatz
2010Middleware for Tactical Military Networks
Barz, C.; Jansen, N.; Thomas, D.
Konferenzbeitrag
2006Thesaurus - Technical Report and User's Guide for the PRIME Project "Research on Fora"
Thomas, D.; Nugroho, Y.; Edler, J.; Ruhland, S.; Propp, T.; Joly, P.-B.; Nedeva, M.
Vortrag