Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP)
Schäfer, S.M.G.; Sendetski, M.; Angioni, C.; Nüsing, R.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2019Novel Approaches to Persistent Pain Therapy
Sisignano, M.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2019Potential biomarkers for persistent and neuropathic pain therapy
Sisignano, M.; Lötsch, J.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2018The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue
Kern, K.; Schäfer, S.M.G; Cohnen, J.; Pierre, S.; Osthues, T.; Tarighi, N.; Hohmann, S.; Ferreiros, N.; Brüne, B.; Weigert, A.; Geisslinger, G.; Sisignano, M.; Scholich, K.
Zeitschriftenaufsatz
2018The oxidized linoleic acid metabolite 12,13-DiHOME mediates thermal hyperalgesia during inflammatory pain
Zimmer, B.; Angioni, C.; Osthues, T.; Toewe, A.; Thomas, D.; Pierre, S.C.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2017The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity
Hohmann, S.W.; Angioni, C.; Tunaru, S.; Lee, S.; Woolf, C.J.; Offermanns, S.; Geisslinger, G.; Scholich, K.; Sisignano, M.
Zeitschriftenaufsatz
2017GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation
Pierre, S.; Linke, B.; Suo, J.; Tarighi, N.; Turco, D. del; Thomas, D.; Ferreiros, N.; Stegner, D.; Frölich, S.; Sisignano, M.; Santos, S.M. dos; Debruin, N.; Nüsing, R.M.; Deller, T.; Nieswandt, B.; Geisslinger, G.; Scholich, K.
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2017The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons
Zinn, S.; Sisignano, M.; Kern, K.; Pierre, S.; Tunaru, S.; Jordan, H.; Suo, J.; Treutlein, E.M.; Angioni, C.; Ferreiros, N.; Leffler, A.; DeBruin, N.; Offermanns, S.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz
2017Next-generation sequencing of the human TRPV1 gene and the regulating co-players LTB4R and LTB4R2 based on a custom AmpliSeq (TM) panel
Kringel, D.; Sisignano, M.; Zinn, S.; Lötsch, J.
Zeitschriftenaufsatz
2017Oxidized lipids in the treatment of chronic or neuropathic pain
Sisignano, Marco; Geisslinger, Gerd; Parnham, Michael John
Patent
2016Drug repurposing for the development of novel analgesics
Sisignano, M.; Parnham, M.J.; Geisslinger, G.
Zeitschriftenaufsatz
2016Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain
Sisignano, M.; Angioni, C.; Park, C.-K.; Santos, S.M.D.; Jordan, H.; Kuzikov, M.; Liu, D.; Zinn, S.; Hohman, S.W.; Schreiber, Y.; Zimmer, B.; Schmidt, M.; Lu, R.; Suo, J.; Zhang, D.-D.; Schäfer, S.M.G.; Hofmann, M.; Yekkirala, A.S.; De Bruin, N.; Parnham, M.J.; Woolf, C.J.; Ji, R.-R.; Scholich, K.; Geisslinger, G.
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2014BKCa channels expressed in sensory neurons modulate inflammatory pain in mice
Lu, R.; Lukowski, R.; Sausbier, M.; Zhang, D.D.; Sisignano, M.; Schuh, C.D.; Kuner, R.; Ruth, P.; Geisslinger, G.; Schmidtko, A.
Zeitschriftenaufsatz
2014Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block
Brenneis, C.; Kistner, K.; Puopolo, M.; Jo, S.; Roberson, D.P.; Sisignano, M.; Segal, D.; Cobos, E.J.; Wainger, B.J.; Labocha, S.; Ferreirós, N.; Hehn, C. von; Tran, J.; Geisslinger, G.; Reeh, P.W.; Bean, B.P.; Woolf, C.J.
Zeitschriftenaufsatz
2014Genome-Wide Transcriptional Profiling of Skin and Dorsal Root Ganglia after Ultraviolet-B-Induced Inflammation
Dawes, J.M.; Antunes-Martins, A.; Perkins, J.R.; Paterson, K.J.; Sisignano, M.; Schmid, R.; Rust, W.; Hildebrandt, T.; Geisslinger, G.; Orengo, C.; Bennett, D.L.; McMahon, S.B.
Zeitschriftenaufsatz
2014Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain
Sisignano, M.; Baron, R.; Scholich, K.; Geisslinger, G.
Zeitschriftenaufsatz
2014Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity
Kallenborn-Gerhardt, W.; Hohmann, S.W.; Syhr, K.M.J.; Schröder, K.; Sisignano, M.; Weigert, A.; Lorenz, J.E.; Lu, R.R.; Brüne, B.; Brandes, R.P.; Geisslinger, G.; Schmidtko, A.
Zeitschriftenaufsatz
2014TRP-channels as key integrators of lipid pathways in nociceptive neurons
Sisignano, M.; Bennett, D.L.H.; Geisslinger, G.; Scholich, K.
Zeitschriftenaufsatz