Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities
Teyra, J.; Ernst, A.; Singer, A.; Sicheri, F.; Sidhu, S.S.
2020Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
Maculins, T.; Garcia-Pardo, J.; Skenderovic, A.; Gebel, J.; Putyrski, M.; Vorobyov, A.; Busse, P.; Varga, G.; Kuzikov, M.; Zaliani, A.; Rahighi, S.; Schaeffer, V.; Parnham, M.J.; Sidhu, S.S.; Ernst, A.; Dötsch, V.; Akutsu, M.; Dikic, I.
2018Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency
Canny, M.D.; Moatti, N.; Wan, L.C.K.; Fradet-Turcotte, A.; Krasner, D.; Mateos-Gomez, P.A.; Zimmermann, M.; Orthwein, A.; Juang, Y.-C.; Zhang, W.; Noordermeer, S.M.; Seclen, E.; Wilson, M.D.; Vorobyov, A.; Munro, M.; Ernst, A.; Ng, T.F.; Cho, T.; Cannon, P.M.; Sidhu, S.S.; Sicheri, F.; Durocher, D.
2017Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10
Zhang, W.; Sartori, M.A.; Makhnevych, T.; Federowicz, K.E.; Dong, X.; Liu, L.; Nim, S.; Dong, A.; Yang, J.; Li, Y.; Haddad, D.; Ernst, A.; Heerding, D.; Tong, Y.; Moffat, J.; Sidhu, S.S.
2017Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha‐helical ubiquitin interacting motif
Manczyk, N.; Yates, B.P.; Veggiani, G.; Ernst, A.; Sicheri, F.; Sidhu, S.S.
2016Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins
Stolz, A.; Putyrski, M.; Kutle, I.; Huber, J.; Wang, C.; Major, V.; Sidhu, S.S.; Youle, R.J.; Rogov, V.V.; Dötsch, V.; Ernst, A.; Dikic, I.