Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Aligning Subjective Ratings in Clinical Decision Making
Pick, Annika; Ginzel, Sebastian; Rüping, Stefan; Sander, Jil; Foldenauer, Ann Christina; Köhm, Michaela
Konferenzbeitrag
2020Bildgebung bei der Psoriasisarthritis und Aspekte der röntgenologischen Progression
Baraliakos, X.; Kleyer, A.; Simon, D.; Köhm, M.; Ohrndorf, S.; Sewerin, P.
Zeitschriftenaufsatz
2020Correction to: Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study
Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M.
Zeitschriftenaufsatz
2020Does concomitant methotrexate confer clinical benefits in patients treated with prior biologic therapy?
Schmalzing, M.; Behrens, F.; Schwaneck, E.C.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P.
Zeitschriftenaufsatz
2020Frühe, zeitlich begrenzte intensive immunmodulatorische Therapie zum Erreichen einer Remission in Psoriasis Arthritis
Köhm, M.
Zeitschriftenaufsatz
2020Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups
Assmann, G.; Köhm, M.; Schuster, V.; Behrens, F.; Mössner, R.; Magnolo, N.; Oji, V.; Burkhardt, H.; Hüffmeier, U.
Zeitschriftenaufsatz
2020Individual therapeutic DAS28-dcrit responses differentiate between effectiveness of rheumatoid arthritis therapies and reflect patient-reported outcomes
Koehm, M.; McIntosh, M.J.; Hofmann, M.W.; Abraham, V.; Gabay, C.; Choy, E.H.; Kavanaugh, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2020Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis
Frey, S.; Sticht, H.; Wilsmann-Theis, D.; Gerschütz, A.; Wolf, K.; Löhr, S.; Haskamp, S.; Frey, B.; Hahn, M.; Ekici, A.B.; Uebe, S.; Thiel, C.; Reis, A.; Burkhardt, H.; Behrens, F.; Köhm, M.; Rech, J.; Schett, G.; Assmann, G.; Kingo, K.; Koks, S.; Mössner, R.; Prinz, J.C.; Oji, V.; Schulz, P.; Muñoz, L.E.; Kremer, A.E.; Wenzel, J.; Hüffmeier, U.
Zeitschriftenaufsatz
2020Sustained improvement in work outcomes in employed patients with rheumatoid arthritis during 2 years of adalimumab therapy: An observational cohort study
Behrens, F.; Tony, H.-P.; Koehm, M.; Schwaneck, E.C.; Gnann, H.; Greger, G.; Burkhardt, H.; Schmalzing, M.
Zeitschriftenaufsatz
2020Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2020Therapiestrategien der Psoriasisarthritis
Köhm, M.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2019Addition or removal of concomitant methotrexate alters adalimumab effectiveness in rheumatoid arthritis but not psoriatic arthritis
Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Wittig, B.M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H.
Zeitschriftenaufsatz
2019Aktuelle Therapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2019Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants
Löhr, S.; Ekici, A.B.; Uebe, S.; Büttner, C.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Simon, D.; Mössner, R.; Nimeh, A.; Oji, V.; Assmann, G.; Rech, J.; Holmdahl, R.; Burkhardt, H.; Reis, A.; Hüffmeier, U.
Zeitschriftenaufsatz
2019Association analyses of functional NCF1 variants in psoriatic arthritis and psoriasis vulgaris
Hüffmeier, U.D.; Löhr, S.; Ekici, A.B.; Uebe, S.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Mössner, R.; Nimeh, A.; Assmann, G.; Rech, J.; Oji, V.; Holmdahl, R.; Burkhardt, H.; Reis, A.
Abstract
2019Characterization Of Patients With Inflammatory Bowel Disease In The Ankylosing Spondylitis Cohort Prior And During Adalimumab Treatment: Data From A Large German Non-Interventional Study
Köhm, M.; Schmalzing, M.; Schwaneck, E.C.; Gnann, H.; Tony, H.P.; Greger, G.; Boas, A.; Burkhardt, H.; Behrens, F.
Abstract
2019Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab
Mojtahed Poor, S.; Ulshöfer, T.; Gabriel, L.A.; Henke, M.; Köhm, M.; Behrens, F.; Geisslinger, G.; Parnham, M.J.; Burkhardt, H.; Schiffmann, S.
Zeitschriftenaufsatz
2018Minimal disease activity is a stable measure of therapeutic response in psoriatic arthritis patients receiving treatment with adalimumab
Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H.
Zeitschriftenaufsatz
2018Stellenwert der Kombination von Biologika mit Methotrexat in der Behandlung der Psoriasisarthritis - Fragen bleiben offen
Dauth, S.; Köhm, M.; Rossmanith, T.; Herrmann, E.; Lehn, A.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2017Comparative Analysis of Achievement of Individual Important Response Measured By DAS28dcrit in a Randomized Head-to-Head Trial of Tocilizumab Vs. Adalimumab in Active Rheumatoid Arthritis
Koehm, M.; Hofmann, M.; Lüthje, R.; McIntosh, M.; Abraham, V.; Gabay, C.; Kavanaugh, A.; Burkhardt, H.; Behrens, F.
Abstract
2017Detection of Clinical Signs of Arthritis and Subclinical Evidence of Inflammation in Psoriasis Patients with Risk for Arthritis: Value of Clinical Examination, Ultrasound and Fluorescence-Optical Imaging - Results from the Prospective Multicentre Xciting Study
Koehm, M.; Rossmanith, T.; Langer, H.E.; Backhaus, M.; Burmester, G.R.; Wassenberg, S.; Köhler, B.; Burkhardt, H.; Behrens, F.
Abstract
2017Impact of rituximab in combination with leflunomide and rituximab retreatment with two different dosages on patient-reported outcomes: results from a multicenter randomized placebo controlled investigator initiated clinical trial in active rheumatoid arthritis (AMARA-STUDY)
Köhm, M.; Rossmanith, T.; Dauth, S.; Alten, R.; Aringer, M.; Backhaus, M.; Burmester, G.; Feist, E.; Kellner, H.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Tony, H.P.; Wassenberg, S.; Burkhardt, H.; Behrens, F.
Abstract
2017Psoriasisarthritis. Aktuelle therapeutische Standards
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2016Achievement of individual important response measured by Das28dcrit in active rheumatoid arthritis when treated with tocilizumab
Behrens, F.; Köhm, M.; Hofmann, M.; Fliedner, G.; Specker, C.; Burkhardt, H.
Abstract
2016Anti-citrullinated protein antibodies are linked to erosive disease in an observational study of patients with psoriatic arthritis
Behrens, F.; Koehm, M.; Thaci, D.; Gnann, H.; Greger, G.; Wittig, B.M.; Burkhardt, H.
Zeitschriftenaufsatz
2016Association analysis of psoriasis vulgaris and psoriatic arthritis with loss-of-function mutations in IL36RN in German patients
Löhr, S.; Uebe, S.; Behrens, F.; Böhm, B.; Köhm, M.; Traupe, H.; Oji, V.; Burkhardt, H.; Reis, A.; Hüffmeier, U.
Zeitschriftenaufsatz
2016Association of Improvement in Pain with Therapeutic Response as Determined by Individual Improvement Criteria in Patients with Rheumatoid Arthritis
Scharbatke, E.C.; Behrens, F.; Schmalzing, M.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P.
Zeitschriftenaufsatz
2016Characterization of Ra patients with a DAS28 response to adalimumab therapy by improvement in pain: A german nonintervention study
Köhm, M.; Scharbatke, E.; Stemmler, E.; Greger, G.; Behrens, F.; Wittig, B.
Abstract
2016Detection of psoriatic arthritis in patients with psoriasis in daily routine care using questionnaires for diagnosis of psoriatic arthritis and fluorescence-optical imaging technique
Köhm, M.; Rossmanith, T.; Langer, H.E.; Burmester, G.; Wassenberg, S.; Kaesser, U.; Backhaus, M.; Burkhardt, H.; Behrens, F.
Abstract
2016Does concomitant methotrexate with adalimumab influence treatment outcomes in patients with psoriatic arthritis? Data from a large observational study
Behrens, F.; Koehm, M.; Arndt, U.; Wittig, B.M.; Greger, G.; Thaci, D.; Scharbatke, E.; Tony, H.-P.; Burkhardt, H.
Zeitschriftenaufsatz
2016Effectiveness of Different Dosages of Retreatment of Rituximab in Combination with Leflunomide: Results from a Multicenter Randomized Placebo Controlled Investigator Initiated Clinical Trial in Active Rheumatoid Arthritis (Amara-Study
Behrens, F.; Rossmanith, T.; Koehm, M.; Alten, R.; Aringer, M.; Burmester, G.R.; Feist, E.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Wassenberg, S.; Tony, H.P.; Kellner, H.; Backhaus, M.; Burkhardt, H.
Abstract
2016Minimal Disease Activity Is a Stable Measure of Therapeutic Response in Psoriatic Arthritis Patients Receiving Treatment with Adalimumab
Behrens, F.; Koehm, M.; Schwaneck, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Tony, H.P.; Burkhardt, H.
Abstract
2016The Predict Study: low risk for digital ulcer development in patients with systemic sclerosis with increasing disease duration and lack of topoisomerase-1 antibodies
Hunzelmann, N.; Riemekasten, G.; Becker, M.O.; Moinzadeh, P.; Kreuter, A.; Melchers, I.; Mueller-Ladner, U.; Meier, F.; Worm, M.; Lee, H.; Herrgott, I.; Pfeiffer, C.; Fierlbeck, G.; Henes, J.; Juche, A.; Zeidler, G.; Mensing, H.; Günther, C.; Sárdy, M.; Burkhardt, H.; Koehm, M.; Kuhr, K.; Krieg, T.; Sunderkötter, C.
Zeitschriftenaufsatz
2016Predictive Value of Different Tools for Detection of Psoriatic Arthritis in Patients with Psoriasis in Daily Routine Care Using Questionnaires for Diagnosis of Psoriatic Arthritis and Fluorescence-Optical Imaging Technique
Koehm, M.; Rossmanith, T.; Langer, H.E.; Burmester, G.R.; Wassenberg, S.; Köhler, B.; Kaesser, U.; Backhaus, M.; Burkhardt, H.; Behrens, F.
Abstract
2016Psoriatic arthritis
Koehm, M.; Behrens, F.
Aufsatz in Buch
2016Rituximab in combination with leflunomide: Results from a multicenter randomized placebo controlled investigator initiated clinical trial in active rheumatoid arthritis (Amara-Study)
Behrens, F.; Rossmanith, T.; Köhm, M.; Alten, R.; Aringer, M.; Backhaus, M.; Baerwald, C.; Burmester, G.; Feist, E.; Kellner, H.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Tony, H.P.; Wassenberg, S.; Burkhardt, H.
Abstract
2016Tight-Control der Entzündungsaktivität in der Therapie der frühen Psoriasisarthritis Eine sinnvolle Therapiestrategie zur Verbesserung der Patientenversorgung?
Köhm, M.
Zeitschriftenaufsatz
2015Anti-TNF-α therapy as an evidence-based treatment option for different clinical manifestations of psoriatic arthritis
Köhm, M.; Burkhardt, H.; Behrens, F.
Zeitschriftenaufsatz
2015Brauchen wir noch klinische Studien in der Rheumatologie?
Henkemeier, U.; Alten, R.; Bannert, B.; Baraliakos, X.; Behrens, F.; Heldmann, F.; Kiltz, U.; Köhm, M.; König, R.; Leipe, J.; Müller-Ladner, U.; Rech, J.; Riechers, E.; Rubbert-Roth, A.; Schmidt, R.E.; Schulze-Koops, H.; Specker, C.; Tausche, A.-K.; Wassenberg, S.; Witt, M.; Witte, T.; Zernicke, J.; Burkhardt, H.
Zeitschriftenaufsatz
2015Non-response to Antitnf treatment in psoriatic arthritis can be predicted by an objective automated measurement of fluorescence-signal intensities in fluorescence-optical imaging technique - the first interims analysis of the xplore-study
Koehm, M.; Rossmanith, T.; Henkemeier, U.; Aries, P.; Alten, R.; Langer, H.-E.; Burkhardt, H.; Behrens, F.
Abstract
2015Pharmakotherapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Zeitschriftenaufsatz
2015Predictors of therapeutic response in ankylosing spondylitis patients initiating therapy with adalimumab in a german non-interventional study
Koehm, M.; Behrens, F.; Scharbatke, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Wittig, B.; Tony, H.P.; Burkhardt, H.
Abstract
2015SAT0070 Association of Improvement in Pain with Therapeutic Response as Determined by Individual Significant Improvement Criteria in Patients with Rheumatoid Arthritis
Scharbatke, E.; Behrens, F.; Schmalzing, M.; Koehm, M.; Greger, G.; Gnann, H.; Tony, H.P.; Burkhardt, H.
Abstract
2015SAT0574 Detection of Subclinical Signs of Musculoskeletal Inflammation by Use of Fluorescence-Optical Imaging Technique in Patients with Psoriasis – Data of the First Interims Analysis of the Xciting Study
Koehm, M.; Rossmanith, T.; Langer, H.E.; Backhaus, M.; Kaesser, U.; Kneitz, C.; Wassenberg, S.; Burkhardt, H.; Behrens, F.
Abstract
2014Effects of methotrexate on anti-TNF treatment in rheumatoid arthritis
Schmalzing, M.; Behrens, F.; Scharbatke, E.C.; Koehm, M.; Wittig, B.; Greger, G.; Burkhardt, H.; Tony, H.P.
Abstract
2014Rheumatoid factor status is a predictor of osteoporosis in patients with psoriatic arthritis
Behrens, F.; Koehm, M.; Scharbatke, E.C.; Wittig, B.; Schmalzing, M.; Gnann, H.; Lorenz, H.M.; Thaci, D.; Burkhardt, H.
Abstract
2014SAT0358 impact of methotrexate on anti-TNF treatment in psoriatic arthritis? An in-depth analysis of a large prospective observational study with adalimumab
Behrens, F.; Köhm, M.; Arndt, U.; Wittig, B.; Greger, G.; Thaci, D.; Scharbatke, E.; Tony, H.P.; Burkhardt, H.
Abstract
2014Validity of additional use of optical immunofluorescence imaging technique (Xiralite®) in detection of active psoriatic arthritis and measurement of disease activity in patients with psoriasis and psoriatic arthritis
Köhm, M.; Roßmanith, T.; Burkhardt, H.; Behrens, F.
Abstract
2013Development and validation of a new disease activity score in 28 joints–based treatment response criterion for rheumatoid arthritis
Behrens, F.; Tony, H.-P.; Alten, R.; Kleinert, S.; Scharbatke, E.C.; Köhm, M.; Gnann, H.; Tams, J.; Greger, G.; Burkhardt, H.
Zeitschriftenaufsatz
2013DMARD-Versager vs. TNF-Versager bei aktiver Psoriasis-Arthritis: Vergleichende Untersuchung zu Krankheitscharakteristika aus einer großen prospektiven Observationsstudie vor Einleitung einer Therapie mit Adalimumab
Behrens, F.; Köhm, M.; Thaci, D.; Krummel-Lorenz, B.; Greger, G.; Wittig, B.; Burkhardt, H.
Abstract
2013Gibt es eine Assoziation zwischen Haut- und Gelenkmanifestation bei Patienten mit Psoriasis-Arthritis? – Datenanalyse einer deutschen nichtinterventionellen Studie mit Adalimumab bei aktiver Psoriasis-Arthritis
Köhm, M.; Behrens, F.; Thaci, D.; Krummel-Lorenz, B.; Greger, G.; Wittig, B.; Burkhardt, H.
Abstract
2013Personalisierte Medizin bei Zytokin-gerichteten Therapien
Behrens, F.; Köhm, M.
Zeitschriftenaufsatz
2013Wirksamkeit von Adalimumab bei aktiver Psoriasis-Arthritis und unzureichendem Ansprechen auf bis zu drei Anti-TNF-Vortherapien
Köhm, M.; Behrens, F.; Thaci, D.; Krummel-Lorenz, B.; Greger, G.; Wittig, B.; Burkhardt, H.
Abstract