Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021Advanced flow cytometry assays for immune monitoring of CAR-T cell applications
Blache, Ulrich; Weiss, Ronald; Boldt, Andreas; Kapinsky, Michael; Blaudszun, André-René; Quaiser, Andrea; Pohl, Annabelle; Miloud, Tewfik; Burgaud, Mégane; Vucinic, Vladan; Platzbecker, Uwe; Sack, Ulrich; Fricke, Stephan; Koehl, Ulrike
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2020Biotechnologische Innovationen im Bereich zellulärer Therapien
Koehl, Ulrike; Augustin, Jens; Quaiser, Andrea; Blaudszun, André-René; Vucinic, Vladan; Platzbecker, Uwe; Aleksandrova, Krasimira; Kebbel, Kati; Schmiedeknecht, Gerno; Fricke, Stephan
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2020Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues
Winkel, A.; Jaimes, Y.; Melzer, C.; Dillschneider, P.; Hartwig, H.; Stiesch, M.; Ohe, J. von der; Strauss, S.; Vogt, P.M.; Hamm, A.; Burmeister, L.; Roger, Y.; Elger, K.; Floerkemeier, T.; Weissinger, E.M.; Pogozhykh, O.; Müller, T.; Selich, A.; Rothe, M.; Petri, S.; Köhl, U.; Hass, R.; Hoffmann, A.
Zeitschriftenaufsatz
2020Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues
Winkel, Andreas; Jaimes, Yarúa; Melzer, Catharina; Dillschneider, Philipp; Hartwig, Henning; Stiesch, Meike; Ohe, Juliane von der; Strauss, Sarah; Vogt, Peter M.; Hamm, Anika; Burmeister, Laura; Roger, Yvonne; Elger, Kristen; Floerkemeier, Thilo; Weissinger, Eva M.; Pogozhykh, Olena; Müller, Thomas; Selich, Anton; Rothe, Michael; Petri, Susanne; Koehl, Ulrike; Hass, Ralf; Hoffmann, Andrea
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2020Editorial: Modulation of human immune parameters by anticancer therapies
Sack, Ulrich; Tárnok, Attila; Preijers, Frank; Koehl, Ulrike; Na, Il-Kang
Zeitschriftenaufsatz
2020Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo
Warnecke, Athanasia; Harre, Jennifer; Staecker, Hinrich; Prenzler, Nils; Strunk, Dirk; Couillard-Despres, Sebastien; Romanelli, Pasquale; Hollerweger, Julia; Lassacher, Teresa; Auer, Daniela; Pachler, Karin; Wietzorrek, Georg; Koehl, Ulrike; Lenarz, Thomas; Schallmoser, Katharina; Laner-Plamberger, Sandra; Falk, Christine S.; Rohde, Eva; Gimona, Mario
Zeitschriftenaufsatz
2020Flow cytometric measurement of STAT5 phosphorylation in cytomegalovirus‐stimulated T cells
Bitar, Michael; Boettcher, Michael; Boldt, Andreas; Hauck, Fabian; Koehl, Ulrike; Liebert, Uwe G.; Magg, Thomas; Schulz, Marian S.; Sack, Ulrich
Zeitschriftenaufsatz
2020From cancer to immune-mediated diseases and tolerance induction: Lessons learned from immune oncology and classical anti-cancer treatment
Klöß, Stephan; Dehmel, Susann; Braun, Armin; Parnham, Michael J.; Koehl, Ulrike; Schiffmann, Susanne
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2020Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: An analysis from the European Society for Blood and Marrow Transplantation
Heilig, Christoph E.; Badoglio, Manuela; Labopin, Myriam; Fröhling, Stefan; Secondino, Simona; Heinz, Jürgen; Nicolas-Virelizier, Emanuelle; Blaise, Didier; Korenbaum, Clément; Santoro, Armando; Verbeek, Mareike; Krüger, William; Siena, Salvatore; Passweg, Jakob R.; Nicola, Massimo di; Rifón, Jose; Dreger, Peter; Koehl, Ulrike; Chabannon, Christian; Pedrazzoli, Paolo
Zeitschriftenaufsatz
2020Harnessing NK cell checkpoint-modulating immunotherapies
Chauhan, Sachin Kumar Singh; Koehl, Ulrike; Klöß, Stephan
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2020High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia
Müller, Stephan A.; Bexte, Tobias; Gebel, Veronika; Kalensee, Franziska; Stolzenberg, Eva; Hartmann, Jessica; Koehl, Ulrike; Schambach, Axel; Wels, Winfried S.; Modlich, Ute; Ullrich, Evelyn
Zeitschriftenaufsatz
2020Management of adults and children undergoing chimeric antigen receptor T-cell therapy: Best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE)
Yakoub-Agha, Ibrahim; Chabannon, Christian; Bader, Peter; Basak, Grzegorz W.; Bönig, Halvard B.; Ciceri, Fabio; Corbacioglu, Selim; Duarte, Rafael F.; Einsele, Hermann; Hudecek, Michael; Kersten, Marie José; Koehl, Ulrike; Kuball, Jürgen H.E.; Mielke, Stephan; Mohty, Mohamad; Murray, John; Nagler, Arnon; Robinson, Stephen; Saccardi, Riccardo; Sanchez-Guijo, Fermin; Snowden, John A.; Srour, Micha; Styczynski, Jan; Urbano-Ispizua, Alvaro; Hayden, Patrick J.; Kröger, Nicolaus M.
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2020New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions
Saidu, Nathaniel Edward Bennett; Bonini, Chiara; Dickinson, Anne M.; Grce, Magdalena; Inngjerdingen, Marit; Koehl, Ulrike; Toubert, Antoine; Zeiser, Robert; Galimberti, Sara
Zeitschriftenaufsatz
2020Nicotinamide Inhibits Self-renewal and Induces Granulocyte Differentiation of Multipotent Progenitor Cells
Nasr, Waseem; Fabian, Claire; Arnold, Katrin; Köhl, Ulrike; Sack, Ulrich; Weiss, Ronald; Cross, Michael; Hauschildt, Sunna
Zeitschriftenaufsatz
2020The role of lncRNAs TAPIR-1 and -2 as diagnostic markers and potential therapeutic targets in prostate cancer
Friedrich, Maik; Wiedemann, Karolin; Reiche, Kristin; Puppel, Sven Holger; Pfeifer, Gabriele; Zipfel, Ivonne; Binder, Stefanie; Koehl, Ulrike; Müller, Gerd A.; Engeland, Kurt; Aigner, Achim; Füssel, Susanne; Fröhner, Michael; Peitzsch, Claudia; Dubrovska, Anna; Rade, Michael; Christ, Sabina; Schreiber, Stephan; Hackermüller, Jörg; Lehmann, Jörg; Toma, Marieta I.; Muders, Michael H.; Sommer, Ulrich; Baretton, Gustavo B.; Wirth, Manfred P.; Horn, Friedemann
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2020Tumors provoke inflammation and perineural microlesions at adjacent peripheral nerves
Cohnen, Jennifer; Kornstädt, Lisa; Hahnefeld, Lisa; Ferreiros, Nerea; Pierre, Sandra; Koehl, Ulrike; Deller, Thomas; Geisslinger, Gerd; Scholich, Klaus
Zeitschriftenaufsatz
2019Analysis of the therapeutic potential of different administration routes and frequencies of human mesenchymal stromal cells in the SOD1G93A mouse model of amyotrophic lateral sclerosis
Bursch, F.; Rath, K.J.; Sarikidi, A.; Böselt, S.; Kefalakes, E.; Osmanovic, A.; Thau-Habermann, N.; Klöß, S.; Köhl, U.; Petri, S.
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2019CAR-expressing natural killer cells for cancer retargeting
Klöß, Stephan; Kretschmer, Anna; Stahl, Lilly; Fricke, Stephan; Koehl, Ulrike
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2019CAR-T-Zellen: Update 2019
Dluczek, Sarah; Tretbar, Sandy; Fricke, Stephan; Koehl, Ulrike
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2019Cellular therapeutics - living drugs. Editorial
Humpe, Andreas; Köhl, Ulrike
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2019Development of adaptive immune effector therapies in solid tumors
Comoli, P.; Chabannon, C.; Köhl, U.; Lanza, F.; Urbano-Ispizua, A.; Hudecek, M.; Ruggeri, A.; Secondino, S.; Bonini, C.; Pedrazzoli, P.
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2019Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering
Oberschmidt, Olaf; Morgan, Michael A.; Huppert, Volker; Kessler, Jörg; Gardlowski, Tanja; Matthies, Nadine; Aleksandrova, Krasimira; Arseniev, Lubomir; Schambach, Axel; Koehl, Ulrike; Klöß, Stephan
Zeitschriftenaufsatz
2019Ergänzung und Alternative zu CAR-T-Zellen?. CAR-NK-Zellen in der Immunonkologie
Quaiser, Andrea; Koehl, Ulrike
Elektronische Publikation
2019Evaluating STAT5 Phosphorylation as a Mean to Assess T Cell Proliferation
Bitar, Michael; Boldt, Andreas; Freitag, Marie-Theres; Gruhn, Bernd; Koehl, Ulrike; Sack, Ulrich
Zeitschriftenaufsatz
2019Functionality and cell senescence of CD4/CD8-selected CD20 CAR T cells manufactured using the automated CliniMACS Prodigy® platform
Aleksandrova, Krasimira; Leise, Jana; Priesner, Christoph; Melk, Anette; Kubiank, Fanni; Abken, Hinrich; Hombach, Andreas; Aktas, Murat; Essl, Mike; Bürger, Iris; Kaiser, Andrew D.; Rauser, Georg; Jurk, Marion; Goudeva, Lilia; Glienke, Wolfgang; Arseniev, Lubomir; Esser, Ruth; Koehl, Ulrike
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2019Molekulare und zellbasierte Krebstherapie - quo vadis?
Lordick, Florian; Platzbecker, Uwe; Büch, E.; Koehl, Ulrike
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2019Preclinical assessment of suitable natural killer cell sources for chimeric antigen receptor natural killer-based "off-the-shelf" acute myeloid leukemia immunotherapies
Klöß, Stephan; Oberschmidt, Olaf; Dahlke, Julia; Vu, Xuan-Khang; Neudörfl, Christine; Kloos, Arnold; Gardlowski, Tanja; Matthies, Nadine; Heuser, Michael; Meyer, Johann; Sauer, Martin; Falk, Christine S.; Koehl, Ulrike; Schambach, Axel; Morgan, Michael A.
Zeitschriftenaufsatz
2018CAR T Cells in trials: Recent achievements and challenges that remain in the production of modified T cells for clinical applications
Köhl, Ulrike; Arsenieva, Stanislava; Holzinger, Astrid; Abken, Hinrich
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2018Dissecting Epstein-Barr virus-specific T-cell responses after allogeneic EBV-specific T-cell transfer for central nervous system posttransplant lymphoproliferative disease
Schultze-Florey, R.E.; Tischer, S.; Kuhlmann, L.; Hundsdoerfer, P.; Koch, A.; Anagnostopoulos, I.; Ravens, S.; Goudeva, L.; Schultze-Florey, C.; Koenecke, C.; Blasczyk, R.; Koehl, U.; Heuft, H.-G.; Prinz, I.; Eiz-Vesper, B.; Maecker-Kolhoff, B.
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2018Editorial: Tailoring NK cell receptor-ligand interactions: An art in evolution
Köhl, Ulrike; Toubert, Antoine; Pittari, Gianfranco
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2018An exponential regression model reveals the continuous development of B cell subpopulations used as reference values in children
Königs, C.; Schultze-Strasser, S.; Quaiser, A.; Bochennek, K.; Schwabe, D.; Klingebiel, T.E.; Köhl, U.; Cappel, C.; Rolle, U.; Bader, P.; Bremm, M.; Huenecke, S.; Bakhtiar, S.
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2018High-dose vitamin D in Addison's disease regulates T-cells and monocytes. A pilot trial
Penna-Martinez, M.; Filmann, N.; Bogdanou, D.; Shoghi, F.; Huenecke, S.; Schubert, R.; Herrmann, E.; Koehl, U.; Husebye, E.S.; Badenhoop, K.
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2018Immune monitoring in allogeneic hematopoietic stem cell transplant recipients
Greco, R.; Ciceri, F.; Noviello, M.; Bondanza, A.; Vago, L.; Oliveira, G.; Peccatori, J.; Cieri, N.; Ruggeri, A.; Köhl, U.; Fleischhauer, K.; Rocha, V.; Dazzi, F.; Werf, S.M. van der; Eikema, D.J.; Terwel, S.R.; Kuball, J.; Toubert, A.; Chabannon, C.; Bonini, C.
Zeitschriftenaufsatz
2018Joint modeling of immune reconstitution post haploidentical stem cell transplantation in pediatric patients with acute leukemia comparing CD34+-selected to CD3/CD19-depleted grafts in a retrospective multicenter study
Salzmann-Manrique, Emilia; Bremm, Melanie; Hünecke, Sabine; Stech, Milena; Orth, Andreas; Eyrich, Matthias; Schulz, Ansgar; Esser, Ruth; Klingebiel, Thomas; Bader, Peter; Herrmann, Eva; Köhl, Ulrike
Zeitschriftenaufsatz
2018Manufacturing mesenchymal stromal cells for the treatment of graft-versus-host disease
Trento, Cristina; Bernardo, Maria Ester; Nagler, Arnon; Kuçi, Selim; Bornhäuser, Martin; Köhl, Ulrike; Strunk, Dirk; Galleu, Antonio; Sanchez-Guijo, F.; Gaipa, Giuseppe; Introna, Martino; Bukauskas, Adomas; Blanc, Katarina le; Apperley, Jane; Roelofs, Hélène; Campenhout, Ann van; Béguin, Yves P.; Kuball, Jürgen H.E.; Lazzari, Lorenza; Avanzini, Maria Antonietta; Fibbe, Willem E.; Chabannon, Christian; Bonini, Chiara; Dazzi, Francesco
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2018Was ist gesichert bei den Zelltherapien?
Quaiser, A.; Köhl, Ulrike
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2010Regulation of HIV-1 infection in cells derived from purified CD34+ cells through manipulation of APOBEC3G expression
Heinzelmann, A.; Stein, S.; Köhl, U.; Dietrich, U.; Briesen, H. von
Zeitschriftenaufsatz