Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms
Emon, Mohammad Asif; Heinson, Ashley; Wu, Ping; Domingo-Fernández, Daniel; Sood, Meemansa; Vrooman, Henri; Corvol, Christophe; Scordis, Phil; Hofmann-Apitius, Martin; Fröhlich, Holger
Zeitschriftenaufsatz
2020Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice
Birkenbihl, Colin; Emon, Mohammad Asif; Vrooman, Henri; Westwood, Sarah; Lovestone, Simon; Hofmann-Apitius, Martin; Fröhlich, Holger
Zeitschriftenaufsatz
2020Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastoma
Rauschenbach, Laurèl; Wieland, Anja; Reinartz, Roman; Kebir, Sied; Till, Andreas; Darkwah Oppong, Marvin; Dobersalske, Celia; Ullrich, Vivien; Ahmad, Ashar; Jabbarli, Ramazan; Pierscianek, Daniela; Fröhlich, Holger; Simon, Matthias; Brüstle, Oliver; Sure, Ulrich; Glas, Martin; Scheffler, Björn
Zeitschriftenaufsatz
2020Evaluating the Alzheimer's disease data landscape
Birkenbihl, Colin; Salimi, Yasamin; Domingo-Fernandez, Daniel; Lovestone, Simon; Fröhlich, Holger; Hofmann-Apitius, Martin
Zeitschriftenaufsatz
2020GuiltyTargets: Prioritization of Novel Therapeutic Targets with Deep Network Representation Learning
Muslu, Özlem; Hoyt, Charles Tapley; Lacerda, Mauricio Pio de; Hofmann-Apitius, Martin; Fröhlich, Holger
Zeitschriftenaufsatz
2020Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study
Brosseron, Frederic; Kolbe, Carl-Christian; Santarelli, Francesco; Carvalho, Stephanie; Antonell, Anna; Castro-Gomez, Sergio; Tacik, Pawel; Namasivayam, Aishwarya Alex; Mangone, Graziella; Schneider, Reinhard; Latz, Eicke; Wüllner, Ullrich; Svenningsson, Per; Sánchez-Valle, Raquel; Molinuevo, José Luis; Corvol, Jean-Christophe; Heneka, Michael T.; Hofmann-Apitius, Martin; Springstubbe, Stephan; Fröhlich, Holger et al.
Zeitschriftenaufsatz
2020Optimal multiparametric set-up modelled for best survival outcomes in palliative treatment of liver malignancies
Goldstein, Elisha; Yeghiazaryan, Kristina; Ahmad, Ashar; Giordano, Frank A.; Fröhlich, Holger; Golubnitschaja, Olga
Zeitschriftenaufsatz
2020PathME: Pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data
Lemsara, Amina; Ouadfel, Salima; Fröhlich, Holger
Zeitschriftenaufsatz
2020SEEDS: Data driven inference of structural model errors and unknown inputs for dynamic systems biology
Newmiwaka, Tobias; Engelhardt, Benjamin; Wendland, Philipp; Kahl, Dominik; Fröhlich, Holger; Kschischo, Maik
Zeitschriftenaufsatz
2020Variational Autoencoder Modular Bayesian Networks for Simulation of Heterogeneous Clinical Study Data
Gootjes-Dreesbach, Luise; Sood, Meemansa; Sahay, Akrishta; Hofmann-Apitius, Martin; Fröhlich, Holger
Zeitschriftenaufsatz
2020Voice perturbations under the stress overload in young individuals: Phenotyping and suboptimal health as predictors for cascading pathologies
Kunin, Anatolij; Sargheini, Nafiseh; Birkenbihl, Colin; Moiseeva, Natalia; Fröhlich, Holger; Golubnitschaja, Olga
Zeitschriftenaufsatz
2019Deep learning for clustering of multivariate clinical patient trajectories with missing values
Jong, Johann de; Emon, Mohammad Asif; Wu, Ping; Karki, Reagon; Sood, Meemansa; Godard, Patrice; Ahmad, Ashar; Vrooman, Henri; Hofmann-Apitius, Martin; Fröhlich, Holger
Zeitschriftenaufsatz
2019The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling
Mubeen, Sarah; Hoyt, Charles Tapley; Gemünd, André; Hofmann-Apitius, Martin; Fröhlich, Holger; Domingo-Fernandez, Daniel
Zeitschriftenaufsatz
2019MCMC Techniques for Parameter Estimation of ODE Based Models in Systems Biology
Valderrama-Bahamóndez, Gloria I.; Fröhlich, Holger
Zeitschriftenaufsatz
2018Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer's Disease and Reconstruction of Relevant Biological Mechanisms
Khanna, Shashank; Domingo-Fernández, Daniel; Iyappan, Anandhi; Emon, Mohammad Asif; Hofmann-Apitius, Martin; Fröhlich, Holger
Zeitschriftenaufsatz