Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections
Linciano, P.; Pozzi, C.; Iacono, L. dello; Pisa, F. di; Landi, G.; Bonucci, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Witt, G.; Santarem, N.; Baptista, C.; Franco, C.; Moraes, C.B.; Müller, W.; Wittig, U.; Luciani, R.; Sesenna, A.; Quotadamo, A.; Ferrari, S.; Pöhner, I.; Cordeiro-da-Silva, A.; Mangani, S.; Costantino, L.; Costi, M.P.
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2019EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
Brennecke, P.; Rasina, D.; Aubi, O.; Herzog, K.; Landskron, J.; Cautain, B.; Vicente, F.; Quintana, J.; Mestres, J.; Stechmann, B.; Ellinger, B.; Brea, J.; Kolanowski, JL.; Pilarski, R.; Orzaez, M.; Pineda-Lucena, A.; Laraia, L.; Nami, F.; Zielenkiewicz, P.; Paruch, K.; Hansen, E.; von Kries, J.P.; Neuenschwander, M.; Specker, E.; Bartunek, P.; Simova, S.; Lesnikowski, Z.; Krauss, S.; Lehtio, L.; Bilitewski, U.; Bronstrup, M.; Tasken, K.; Jirgensons, A.; Lickert, H.; Clausen, M.H.; Andersen, J.H.; Vicent, M.J.; Genilloud, O.; Martinez, A.; Nazare, M.; Fecke, W.; Gribbon, P.
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2019Multi-endpoint toxicological assessment of polystyrene nano- and microparticles in different biological models in vitro
Hesler, M.; Aengenheister, L.; Ellinger, B.; Drexel, R.; Straskraba, S.; Jost, C.; Wagner, S.; Meier, F.; Briesen, H. von; Büchel, C.; Wick, P.; Buerki-Thurnherr, T.; Kohl, Y.
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2019SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti- Trypanosoma brucei Agent
Borsari, C.; Santarem, N.; Macedo, S.; Jiménez-Antón, M.D.; Torrado, J.J.; Olías-Molero, A.I.; Corral, M.J.; Tait, A.; Ferrari, S.; Costantino, L.; Luciani, R.; Ponterini, G.; Gul, S.; Kuzikov, M.; Ellinger, B.; Behrens, B.; Reinshagen, J.; Alunda, J.M.; Cordeiro-Da-Silva, A.; Costi, M.P.
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2018Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
Linciano, P.; Moraes, C.B.; Alcantara, L.M.; Franco, C.H.; Pascoalino, B.; Freitas-Junior, L.H.; Macedo, S.; Santarem, N.; Cordeiro-da-Silva, A.; Gul, S.; Witt, G.; Kuzikov, M.; Ellinger, B.; Ferrari, S.; Luciani, R.; Quotadamo, A.; Costantino, L.; Costi, M.P.
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2018Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
Uliassi, E.; Piazzi, L.; Belluti, F.; Mazzanti, A.; Kaiser, M.; Brun, R.; Moraes, C.B.; Freitas-Junior, L.H.; Gul, S.; Kuzikov, M.; Ellinger, B.; Borsari, C.; Costi, M.P.; Bolognesi, M.L.
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2018A unique fungal strain collection from Vietnam characterized for high performance degraders of bioecological important biopolymers and lipids
Brandt, S.C.; Ellinger, B.; Nguyen, T. van; Thi, Q.D.; Nguyen, G. van; Baschien, C.; Yurkov, A.; Hahnke, R.L.; Schäfer, W.; Gand, M.
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2017Comparison of in-vitro and ex-vivo wound healing assays for the investigation of diabetic wound healing and demonstration of a beneficial effect of a triterpene extract
Ueck, C.; Volksdorf, T.; Houdek, P.; Vidal-Y-Sy, S.; Sehner, S.; Ellinger, B.; Lobmann, R.; Larena-Avellaneda, A.; Reinshagen, K.; Ridderbusch, I.; Kohrmeyer, K.; Moll, I.; Daniels, R.; Werner, P.; Merfort, I.; Brandner, J.M.
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2017Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity
Uliassi, E.; Fiorani, G.; Krauth-Siegel, R.L.; Bergamini, C.; Fato, R.; Bianchini, G.; Carlos Menéndez, J.; Molina, M.T.; López-Montero, E.; Falchi, F.; Cavalli, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Witt, G.; Moraes, C.B.; Freitas-Junior, L.H.; Borsari, C.; Costi, M.P.; Bolognesi, M.L.
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2017Establishing the Secondary Metabolite Profile of the Marine Fungus: Tolypocladium geodes sp MF458 and Subsequent Optimisation of Bioactive Secondary Metabolite Production
Kebede, B.; Wrigley, S.K.; Prashar, A.; Rahlff, J.; Wolf, M.; Reinshagen, J.; Gribbon, P.; Imhoff, J.F.; Silber, J.; Labes, A.; Ellinger, B.
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2017Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Linciano, P.; Dawson, A.; Pöhner, I.; Costa, D.M.; Sá, M.S.; Cordeiro-da-Silva, A.; Luciani, R.; Gul, S.; Witt, G.; Ellinger, B.; Kuzikov, M.; Gribbon, P.; Reinshagen, J.; Wolf, M.; Behrens, B.; Hannaert, V.; Michels, P.A.M.; Nerini, E.; Pozzi, C.; Pisa, F. di; Landi, G.; Santarem, N.; Ferrari, S.; Saxena, P.; Lazzari, S.; Cannazza, G.; Freitas-Junior, L.H.; Moraes, C.B.; Pascoalino, B.S.; Alcântara, L.M.; Bertolacini, C.P.; Fontana, V.; Wittig, U.; Müller, W.; Wade, R.C.; Hunter, W.N.; Mangani, S.; Costantino, L.; Costi, M.P.
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2017Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds
Borsari, C.; Santarem, N.; Torrado, J.; Olías, A.I.; Corral, M.J.; Baptista, C.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Witt, G.; Gribbon, P.; Reinshagen, J.; Linciano, P.; Tait, A.; Costantino, L.; Freitas-Junior, L.H.; Moraes, C.B.; Bruno dos Santos, P.; Alcântara, L.M.; Franco, C.H.; Bertolacini, C.D.; Fontana, V.; Tejera Nevado, P.; Clos, J.; Alunda, J.M.; Cordeiro-da-Silva, A.; Ferrari, S.; Costi, M.P.
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2017Ein neuartiger Assay zur Messung chemotaktischer Migration in Echtzeit
O’Clair, L.; Ellinger, B.; Kalmer, M.; Szybut, C.; Borsetti, Y.
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2017Synthesis and Biological Activity of Octaketides from the Cytosporone Family
von Delius, M.; Le, C.M.; Ellinger, B.; Kuzikov, M.; Gul, S.; Dong, V.M.
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2016Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs
Borsari, C.; Lucian, R.; Pozz, C.; Poehner, I.; Henrich, S.; Trande, M.; Cordeiro-Da-silva, A.; Santarem, N.; Baptista, C.; Tait, A.; Di Pisa, F.; Iacono, L.D.; Landi, G.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Reinshagen, J.; Witt, G.; Gribbon, P.; Kohler, M.; Keminer, O.; Behrens, B.; Costantino, L.; Nevado, P.T.; Bifeld, E.; Eick, J.; Clos, J.; Torrado, J.; Jiménez-Antón, M.D.; Corral, M.J.; Alunda, J.Ma.; Pellati, F.; Wade, R.C.; Ferrari, S.; Mangani, S.; Costi, M.P.
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2016Risk mitigation in academic drug discovery
Ellinger, B.; Gribbon, P.
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2014A Phenotypic Screening Approach to Identify Anticancer Compounds Derived from Marine Fungi
Ellinger, B.; Silber, J.; Prashar, A.; Landskron, J.; Weber, J.; Rehermann, S.; Müller, F.J.; Smith, S.; Wrigley, S.; Taskén, K.; Gribbon, P.; Labes, A.; Imhoff, J.F.
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