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| 2020 | Antifibrotic effects of amyloid-beta and its loss in cirrhotic liver
Buniatian, Gayane Hrachia; Weiskirchen, Ralf; Weiss, Thomas S.; Schwinghammer, Ute; Fritz, Martin; Seferyan, Torgom; Proksch, Barbara; Glaser, Michael; Lourhmati, Ali; Buadze, Marine; Borkham-Kamphorst, Erawan; Gaunitz, Frank; Gleiter, Christoph H.; Lang, Thomas; Schaeffeler, Elke; Tremmel, Roman; Cynis, Holger; Frey II, William H.; Gebhardt, Rolf; Friedmann, Scott L.; Mikulits, Wolfgang; Schwab, Matthias; Danielyan, Lusine | Zeitschriftenaufsatz |
| 2020 | Formation of HERV-K and HERV-Fc1 envelope family members is suppressed on transcriptional and translational level
Gröger, Victoria; Wieland, Lisa; Naumann, Marcel; Meinecke, Ann-Christin; Meinhardt, Beate; Roßner, Steffen; Ihling, Christian; Emmer, Alexander; Staege, Martin S.; Cynis, Holger | Zeitschriftenaufsatz |
| 2020 | Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology
Gnoth, Kathrin; Piechotta, Anke; Kleinschmidt, Martin; Konrath, Sandra; Schenk, Mathias; Taudte, Nadine; Ramsbeck, Daniel; Nykiel, Vera; Geißler, Stefanie; Eichentopf, Rico; Barendrecht, Susan; Hartlage-Rübsamen, Maike; Demuth, Hans-Ulrich; Roßner, Steffen; Cynis, Holger; Rahfeld, Jens-Ulrich; Schilling, Stephan | Zeitschriftenaufsatz |
| 2019 | Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells
Barth, Marie; Gröger, Victoria; Cynis, Holger; Staege, Martin Sebastian | Zeitschriftenaufsatz |
| 2019 | Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity
Lienau, Claudia; Gräwert, Tobias; Alves Avelar, Leandro A.; Illarionov, Boris; Held, Jana; Knaab, Tanja C.; Lungerich, Beate; Geelen, Lasse van; Meier, Dieter; Geißler, Stefanie; Cynis, Holger; Riederer, Ulrich; Buchholz, Mirko; Kalscheuer, Rainer; Bacher, Adelbert; Mordmüller, Benjamin; Fischer, Markus; Kurz, Thomas | Zeitschriftenaufsatz |
| 2018 | Dipeptidyl-peptidase activity of meprin β links N-truncation of Aβ with glutaminyl cyclase-catalyzed pGlu-Aβ formation
Schlenzig, Dagmar; Cynis, Holger; Hartlage-Rübsamen, Maike; Zeitschel, Ulrike; Menge, Katja; Fothe, Anja; Ramsbeck, Daniel; Spahn, Claudia; Wermann, Michael; Roßner, Steffen; Buchholz, Mirko; Schilling, Stephan; Demuth, Hans-Ulrich | Zeitschriftenaufsatz |
| 2018 | Human endogenous retroviruses and their putative role in the development of autoimmune disorders such as multiple sclerosis
Gröger, Victoria; Cynis, Holger | Zeitschriftenaufsatz |
| 2018 | Structure-guided design, synthesis, and characterization of next-generation meprin β inhibitors
Ramsbeck, Daniel; Hamann, Antje; Richter, Georg; Schlenzig, Dagmar; Geißler, Stefanie; Nykiel, Vera; Cynis, Holger; Schilling, Stephan; Buchholz, Mirko | Zeitschriftenaufsatz |
| 2016 | Immunotherapy targeting pyroglutamate-3 Aβ
Cynis, Holger; Frost, Jeffrey L.; Crehan, Helen; Lemere, Cynthia A. | Zeitschriftenaufsatz |
| 2015 | Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease
Hartlage-Rübsamen, Maike; Waniek, Alexander; Meißner, Juliane; Morawski, Markus; Schilling, Stephan; Jäger, Carsten; Kleinschmidt, Martin; Cynis, Holger; Kehlen, Astrid; Arendt, Thomas; Demuth, Hans-Ulrich; Roßner, Steffen | Zeitschriftenaufsatz |
| 2015 | Isolation und Kultivierung von Mikrogliazellen aus murinen Hirngewebe und deren Stimulation zur Generierung eines ruhenden adulten Phänotyps
Hietel, Benjamin
: Stohwasser, Ralf (Gutachter); Cynis, Holger (Gutachter) | Bachelor Thesis |
| 2015 | Klonierung, Expression und Reinigung von Hüllproteinen Humaner Endogener Retroviren als Zielproteine in der Multiple Sklerose-Forschung
Zhang, Ziyun
: Mägert, Hans-Jürgen (Gutachter); Cynis, Holger (Gutachter) | Master Thesis |
| 2014 | Glutaminyl cyclase in human cortex: Correlation with (pGlu)-amyloid-β load and cognitive decline in Alzheimer's disease
Morawski, Markus; Schilling, Stephan; Kreuzberger, Moritz; Waniek, Alexander; Jäger, Carsten; Koch, Birgit; Cynis, Holger; Kehlen, Astrid; Arendt, Thomas; Hartlage-Rübsamen, Maike; Demuth, Hans-Ulrich; Roßner, Steffen | Zeitschriftenaufsatz |
| 2014 | Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC
Höfling, Corinna; Indrischek, Henrike; Höpcke, Theodor; Waniek, Alexander; Cynis, Holger; Koch, Birgit; Schilling, Stephan; Morawski, Markus; Demuth, Hans-Ulrich; Roßner, Steffen; Hartlage-Rübsamen, Maike | Zeitschriftenaufsatz |
| 2014 | Pyroglutamate-Amyloid-β and Glutaminyl Cyclase are Colocalized with Amyloid-β in Secretory Vesicles and Undergo Activity-Dependent, Regulated Secretion
Cynis, Holger; Funkelstein, Lydiane; Toneff, T.; Mosier, C.; Ziegler, M.; Koch, Birgit; Demuth, Hans-Ulrich; Hook, V. | Zeitschriftenaufsatz |
| 2013 | Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration
Becker, Andreas; Kohlmann, Stephanie; Alexandru, Anca; Jagla, Wolfgang; Canneva, Fabio; Bäuscher, Christoph; Cynis, Holger; Sedlmeier, Reinhard; Graubner, Sigrid; Schilling, Stephan; Demuth, Hans-Ulrich; Hörsten, Stephan von | Zeitschriftenaufsatz |
| 2013 | Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice
Cynis, Holger; Kehlen, Astrid; Haegele, Monique; Hoffmann, Torsten; Heiser, Ulrich; Fujii, Masato; Shibazaki, Yuichiro; Yoneyama, Hiroyuki; Schilling, Stephan; Demuth, Hans-Ulrich | Zeitschriftenaufsatz |
| 2013 | A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues
Güttler, Bert H.-O.; Cynis, Holger; Seifert, Franziska; Ludwig, Hans-Henning; Porzel, Andrea; Schilling, Stephan | Zeitschriftenaufsatz |