Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2017Characteristics of Genome Editing Mutations in Cereal Crops
Zhu, C.; Bortesi, L.; Baysal, C.; Twyman, R.M.; Fischer, R.; Capell, T.; Schillberg, S.; Christou, P.
Zeitschriftenaufsatz
2016CRISPR/Cas9 activity in the rice OsBEIIb gene does not induce off-target effects in the closely related paralog OsBEIIa
Baysal, C.; Bortesi, L.; Zhu, C.; Farré, G.; Schillberg, S.; Christou, P.
Zeitschriftenaufsatz
2016Patterns of CRISPR/Cas9 activity in plants, animals and microbes
Bortesi, L.; Zhu, C.; Zischewski, J.; Perez, L.; Bassié, L.; Nadi, R.; Forni, G.; Lade, S.B.; Soto, E.; Jin, X.; Medina, V.; Villorbina, G.; Munoz, P.; Farré, G.; Fischer, R.; Twyman, R.M.; Capell, T.; Christou, P.; Schillberg, S.
Zeitschriftenaufsatz
2015Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants
Ma, J.K.-C.; Drossard, J.; Lewis, D.; Altmann, F.; Boyle, J.; Christou, P.; Cole, T.; Dale, P.; van Dolleweerd, C.J.; Isitt, V.; Katinger, D.; Lobedan, M.; Mertens, H.; Paul, M.J.; Rademacher, T.; Sack, M.; Hundleby, P.A.C.; Stiegler, G.; Stoger, E.; Twyman, R.M.; Vcelar, B.; Fischer, R.
Zeitschriftenaufsatz
2013Abscisic acid and the herbicide safener cyprosulfamide cooperatively enhance abiotic stress tolerance in rice
Dashevskaya, S.; Horn, R.; Chudobova, I.; Schillberg, S.; Vélez, S.M.R.; Capell, T.; Christou, P.
Zeitschriftenaufsatz
2006The intracellular fate of a recombinant protein is tissue-dependent
Drakakaki, G.; Marcel, S.; Arcalis, E.; Altmann, F.; Gonzalez-Melendi, P.; Fischer, R.; Christou, P.; Stoger, E.
Zeitschriftenaufsatz
2005Endosperm-specific co-expression of recombinant soybean ferritin and aspergillus phytase in maize results in significant increases in the levels of bioavailable iron
Drakakaki, G.; Marcel, S.; Glahn, R.P.; Lund, E.K.; Pariagh, S.; Fischer, R.; Christou, P.; Stoger, E.
Zeitschriftenaufsatz
2005EU-OSTID: A collection of transposon insertional mutants for functional genomics in rice
Enckevort, L.J.G. van; Droc, G.; Piffanelli, P.; Greco, R.; Gagneur, C.; Weber, C.; Gonzalez, V.M.; Cabot, P.; Fornara, F.; Berri, S.; Miro, B.; Lan, P.; Rafel, M.; Capell, T.; Puigdomenech, P.; Ouwerkerk, P.B.F.; Meijer, A.H.; Pe', E.; Colombo, L.; Christou, P.; Guiderdoni, E.; Pereira, A.
Zeitschriftenaufsatz
2005Large-scale chromatin decondensation induced in a developmentally activated transgene locus
Wegel, E.; Vallejos, R.H.; Christou, P.; Stöger, E.; Shaw, P.
Zeitschriftenaufsatz
2005Molecular farming for new drugs and vaccines
Ma, J.K.-C.; Barros, E.; Bock, R.; Christou, P.; Dale, P.J.; Dix, P.J.; Fischer, R.; Irwin, J.; Mahoney, R.; Pezzotti, M.; Schillberg, S.; Sparrow, P.; Stoger, E.; Twyman, R.M.
Zeitschriftenaufsatz
2005Recent progress in plantibody technology
Stoger, E.; Sack, M.; Nicholson, L.; Fischer, R.; Christou, P.
Zeitschriftenaufsatz
2005A recombinant multimeric immunoglobulin expressed in rice shows assembly-dependent subcellular localization in endosperm cells
Nicholson, L.; Gonzalez-Melendi, P.; Dolleweerd, C. van; Tuck, H.; Perrin, Y.; Ma, J.K.-C.; Fischer, R.; Christou, P.; Stoger, E.
Zeitschriftenaufsatz
2005Sowing the seeds of success. Pharmaceutical proteins from plants
Stoger, E.; Ma, J.K.-C.; Fischer, R.; Christou, P.
Zeitschriftenaufsatz
2004Antibody production in transgenic plants
Stoger, E.; Schillberg, S.; Twyman, R.M.; Fischer, R.; Christou, P.
Aufsatz in Buch
2004Dedifferentiation-mediated changes in transposition behavior make the Activator transposon an ideal tool for functional genomics in rice
Kohli, A.; Prynne, M.Q.; Miro, B.; Pereira, A.; Twyman, R.M.; Capell, T.; Christou, P.
Zeitschriftenaufsatz
2004Handbook of plant biotechnology
: Christou, P.; Klee, H.
Buch
2004Introduction to plant genetic modification: Gene isolation
Christou, P.
Aufsatz in Buch
2004Introns are key regulatory elements of rice tubulin expression
Fiume, E.; Christou, P.; Giani, S.; Breviario, D.
Zeitschriftenaufsatz
2004Modulation of the polyamine biosynthetic pathway in transgenic rice confers tolerance to drought stress
Capell, T.; Bassie, L.; Christou, P.
Zeitschriftenaufsatz
2004Plant biotechnology
Sasaki, T.; Christou, P.
Zeitschriftenaufsatz
2004Plant transformation technology: Particle bombardment
Twyman, R.M.; Christou, P.
Aufsatz in Buch
2004Plant-based production of biopharmaceuticals
Fischer, R.; Stoger, E.; Schillberg, S.; Christou, P.; Twyman, R.M.
Zeitschriftenaufsatz
2004The potential of genetically enhanced plants to address food insecurity
Christou, P.; Twyman, R.M.
Zeitschriftenaufsatz
2004Producing transglutaminases by molecular farming in plants: Minireview article
Capell, T.; Claparols, I.; Duca, S. del; Bassie, L.; Miro, B.; Rodriguez-Montesinos, J.; Christou, P.; Serafini-Fracassini, D.
Zeitschriftenaufsatz
2004Progress in plant metabolic engineering
Capell, T.; Christou, P.
Zeitschriftenaufsatz
2004Transgenic rice as a vehicle for the production of the industrial enzyme transglutaminase
Claparols, M.I.; Bassie, L.; Miro, B.; Duca, S. del; Rodriguez-Montesinos, J.; Christou, P.; Serafini-Fracassini, D.; Capell, T.
Zeitschriftenaufsatz
2004Unexpected deposition patterns of recombinant proteins in post-endoplasmic reticulum compartments of wheat endosperm
Arcalis, E.; Marcel, S.; Altmann, F.; Kolarich, D.; Drakakaki, G.; Fischer, R.; Christou, P.; Stoger, E.
Zeitschriftenaufsatz
2003Cell factories
Twyman, R.M.; Stöger, E.; Christou, P.
Aufsatz in Buch
2003Genetic engineering of secondary metabolism - alcaloids
Twyman, R.M.; Verpoorte, R.; Memelink, J.; Christou, P.
Aufsatz in Buch
2003Molecular farming
Twyman, R.M.; Stöger, E.; Christou, P.
Aufsatz in Buch
2003Molecular farming in plants: Host systems and expression technology
Twyman, R.M.; Stoger, E.; Schillberg, S.; Christou, P.; Fischer, R.
Zeitschriftenaufsatz
2003The production of recombinant pharmaceutical proteins in plants
Ma, J.K.-C.; Drake, P.M.W.; Christou, P.
Zeitschriftenaufsatz
2003Reduction in the endogenous arginine decarboxylase transcript levels in rice leads to depletion of the putrescine and spermidine pools with no concomitant changes in the expression of downstream genes in the polyamine biosynthetic pathway
Trung-Nghia, P.; Bassie, L.; Safwat, G.; Thu-Hang, P.; Lepri, O.; Rocha, P.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
2003Transgene integration, organization and interaction in plants
Kohli, A.; Twyman, R.M.; Abranches, R.; Wegel, E.; Stoger, E.; Christou, P.
Zeitschriftenaufsatz
2003Transgenic Research. Editorial
Christou, P.
Zeitschriftenaufsatz
2002Antibiotic and other marker genes and their potential impact
Christou, P.
Vortrag
2002Decrease in genomic cytosine methylation leads to increased Ac transposition in rice: Implications for saturation insertional mutagenesis
Fiume, E.; Rodriguez, J.; Rafel, M.; Prynne, M.Q.; Gomonda, R.W.J.; Capell, T.; Kohli, A.; Pereira, A.; Christou, P.
Poster
2002Dedifferentiation-mediated hypomethylation leads to increased AC transposition in indica rice. Implications for saturation insertional mutagenesis
Fiume, E.; Rodriguez, J.; Rafel, M.; Prynne, M.Q.; Gomonda, R.W.J.; Bassie, L.; Aguado, E.; Capell, T.; Kohli, A.; Pereira, A.; Christou, P.
Konferenzbeitrag
2002Deletion of the C-terminal 138 amino acids of the wheat FKBP73 abrogates calmodulin binding, dimerization and male fertility in transgenic rice
Kurek, I.; Dulberger, R.; Azem, A.; Tzvi, B.B.; Sudhakar, D.; Christou, P.; Breiman, A.
Zeitschriftenaufsatz
2002Different rice alpha-tubulin isotypes share a common mechanism for transcriptional regulation
Fiume, E.; Christou, P.; Breviario, D.
Konferenzbeitrag
2002Endogenous enzyme activities and polyamine levels in diverse rice cultivars depend on the genetic background and are not affected by the presence of the hygromycin phosphotransferase selectable marker
Lepri, O.; Bassie, L.; Thu-Hang, P.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
2002Expression of a heterologous S-Adenosylmethionine Decarboxylase cDNA in plants demonstrates that changes in S-Adenosyl-L-Methionine Decarboxylase activity determine levels of the higher polyamines spermidine and spermine
Thu-Hang, P.; Bassie, L.; Safwat, G.; Trung-Nghia, P.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
2002Functional expression of tropinone reductase I (trI) and hyoscyamine-6beta-hydroxylase (h6h) from Hyoscyamus niger in Nicotiana tabacum
Rocha, P.; Stenzel, O.; Parr, A.; Walton, N.; Christou, P.; Dräger, B.; Leech, M.J.
Zeitschriftenaufsatz
2002Generation and preliminary metabolic profiling of transgenic rice plants accumulating putrescine
Bassie, L.; Aguado, E.; Fiume, E.; Christou, P.; Capell, T.
Konferenzbeitrag
2002Linear transgene constructs lacking vector backbone sequences generate transgenic rice plants which accumulate higher levels of proteins conferring insect resistance
Thi Loc, N.; Tinjuangjun, P.; Gatehouse, A.M.R.; Christou, P.; Gatehouse, J.A.
Zeitschriftenaufsatz
2002Over-expression of a rat transglutaminase ORF in transgenic rice (Oryza sativa L.) molecular and biochemical analyses
Claparols, I.; Bassie, L.; Aguado, E.; Duca, S. del; Sefarini-Fracasini, D.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
2002Overexpression of the wheat FK506-binding protein 73 (FKBP73) and the heat-induced wheat FKBP77 in transgenic wheat reveals different functions of the two isoforms
Kurek, I.; Stöger, E.; Dulberger, R.; Christou, P.; Breiman, A.
Zeitschriftenaufsatz
2002Plantibodies. Applications, advantages and bottlenecks
Stoger, E.; Sack, M.; Fischer, R.; Christou, P.
Zeitschriftenaufsatz
2002Les planticorps
Stoger, E.; Sack, M.; Fischer, R.; Christou, P.
Zeitschriftenaufsatz
2002Practical considerations for pharmaceutical antibody production in different crop systems
Stoger, E.; Sack, M.; Perrin, Y.; Vaquero, C.; Torres, E.; Twyman, R.M.; Christou, P.; Fischer, R.
Zeitschriftenaufsatz
2002Regeneration of Lonicera tatarica plants via adventitious organogenesis from cultured stem explants
Palacios, N.; Christou, P.; Leech, M.J.
Zeitschriftenaufsatz
2002Transgenic plants as a useful tool to study the biochemistry of down-regulation of an endogenous rice gene using a pea diamine oxidase cDNA
Bassie, L.; Aguado, E.; Fiume, E.; Christou, P.; Capell, T.
Poster
2002Transgenic rice plants that over-express the oat arginine decarboxylase cDNA constitutively show enhanced tolerance to drought stress
Aguado, E.; Bassie, L.; Fiume, E.; Christou, P.; Capell, T.
Konferenzbeitrag
2002Transgenic rice. An ideal experimental system for fundamental science and applications
Christou, P.
Konferenzbeitrag
2001Native and artificial reticuloplasmins co-accumulate in distinct domains of the endoplasmic reticulum and in post-endoplasmic reticulum compartments
Torres, E.; Gonzalez-Melendi, P.; Stöger, E.; Shaw, P.; Twyman, R.M.; Nicholson, L.; Vaquero, C.; Fischer, R.; Christou, P.; Perrin, Y.
Zeitschriftenaufsatz
2001Over-expression of a cDNA for human ornithine decarboxylase in transgenic rice plants alters the polyamine pool in a tissue-specific manner
Lepri, O.; Bassie, L.; Safwat, G.; Thu-Hang, P.; Trung-Nghia, P.; Hölttä, E.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
2000Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies
Stöger, E.; Vaquero, C.; Torres, E.; Sack, M.; Nicholson, L.; Drossard, J.; Williams, S.; Keen, D.; Perrin, Y.; Christou, P.; Fischer, R.
Zeitschriftenaufsatz
2000Transgenic cell lines as a useful tool to study the biochemistry of down-regulation of an endogenous rice gene using a heterologous diamine-oxidase cDNA
Bassie, L.; Noury, M.; Wisniewski, J.P.; Topsom, L.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
2000Transgenic pea seeds as bioreactors for the production of a single-chain Fv fragment (scFV) antibody used in cancer diagnosis and therapy
Perrin, Y.; Vaquero, C.; Gerrard, I.; Sack, M.; Drossard, J.; Stöger, E.; Christou, P.; Fischer, R.
Zeitschriftenaufsatz
2000A transgenic rice cell lineage expressing the oat arginine decarboxylase (adc) cDNA constitutively accumulates putrescine in callus and seeds but not in vegetative tissues
Noury, M.; Bassie, L.; Lepri, O.; Kurek, I.; Christou, P.; Capell, T.
Zeitschriftenaufsatz
1999Rice cell culture as an alternative production system for functional diagnostic and therapeutic antibodies
Torres, E.; Vaquero, C.; Nicholson, L.; Sack, M.; Stöger, E.; Drossard, J.; Christou, P.; Fischer, R.; Perrin, Y.
Zeitschriftenaufsatz