Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021Heteroaromatic inhibitors of the Astacin proteinases Meprin α, Meprin β and Ovastacin discovered by a scaffold‐hopping approach
Tan, Kathrin; Jäger, Christian; Körschgen, Hagen; Geißler, Stefanie; Schlenzig, Dagmar; Buchholz, Mirko; Stöcker, Walter; Ramsbeck, Daniel
Zeitschriftenaufsatz
2020Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility
Kirchberg, Martin; Eick, Sigrun; Buchholz, Mirko; Rosche, Fred; Kiesow, Andreas; Sarembe, Sandra; Mäder, Karsten
Zeitschriftenaufsatz
2020Hydrazides are potent transition-state analogues for glutaminyl cyclase implicated in the pathogenesis of Alzheimer's disease
Kupski, Oliver; Funk, Lisa-Marie; Sautner, Viktor; Seifert, Franziska; Worbs, Brigitte; Ramsbeck, Daniel; Meyer, Franc; Diederichsen, Ulf; Buchholz, Mirko; Schilling, Stephan; Demuth, Hans-Ulrich; Tittmann, Kai
Zeitschriftenaufsatz
2020In vitro evaluation of antimicrobial activity of minocycline formulations for topical application in periodontal therapy
Schmid, Jan-Luca; Kirchberg, Martin; Sarembe, Sandra; Kiesow, Andreas; Sculean, Anton; Mäder, Karsten; Buchholz, Mirko; Eick, Sigrun
Zeitschriftenaufsatz
2020A primary evaluation of potential small-molecule inhibitors of the astacin metalloproteinase ovastacin, a novel drug target in female infertility treatment
Körschgen, Hagen; Jäger, Christian; Tan, Kathrin; Buchholz, Mirko; Stöcker, Walter; Ramsbeck, Daniel
Zeitschriftenaufsatz
2019Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity
Lienau, Claudia; Gräwert, Tobias; Alves Avelar, Leandro A.; Illarionov, Boris; Held, Jana; Knaab, Tanja C.; Lungerich, Beate; Geelen, Lasse van; Meier, Dieter; Geißler, Stefanie; Cynis, Holger; Riederer, Ulrich; Buchholz, Mirko; Kalscheuer, Rainer; Bacher, Adelbert; Mordmüller, Benjamin; Fischer, Markus; Kurz, Thomas
Zeitschriftenaufsatz
2018Dipeptidyl-peptidase activity of meprin β links N-truncation of Aβ with glutaminyl cyclase-catalyzed pGlu-Aβ formation
Schlenzig, Dagmar; Cynis, Holger; Hartlage-Rübsamen, Maike; Zeitschel, Ulrike; Menge, Katja; Fothe, Anja; Ramsbeck, Daniel; Spahn, Claudia; Wermann, Michael; Roßner, Steffen; Buchholz, Mirko; Schilling, Stephan; Demuth, Hans-Ulrich
Zeitschriftenaufsatz
2018Structure-guided design, synthesis, and characterization of next-generation meprin β inhibitors
Ramsbeck, Daniel; Hamann, Antje; Richter, Georg; Schlenzig, Dagmar; Geißler, Stefanie; Nykiel, Vera; Cynis, Holger; Schilling, Stephan; Buchholz, Mirko
Zeitschriftenaufsatz
2018Tertiary‐amine‐based inhibitors of the astacin protease meprin α
Tan, Kathrin; Jäger, Christian; Schlenzig, Dagmar; Schilling, Stephan; Buchholz, Mirko; Ramsbeck, Daniel
Zeitschriftenaufsatz
2016Natural products from microalgae with potential against Alzheimer´s disease
Hielscher-Michael, Stephanie; Griehl, Carola; Buchholz, Mirko; Demuth, Hans-Ulrich; Arnold, Norbert; Wessjohann, Ludger A.
Zeitschriftenaufsatz
2015Synthese neuartiger Inhibitoren bakterieller Glutaminyl-Zyklasen
Strich, Stefanie
: Briel, Detlef (Gutachter); Buchholz, Mirko (Gutachter)
Diplomarbeit
2015Untersuchung von Agonisten des vaskulären endothelialen Wachstumsfaktor Rezeptors-3 (VEGFR-3) durch Verwendung von liganden- und strukturbasierten Methoden
Wieczoreck, Vivien
: Labudde, Dirk (Erstprüfer); Buchholz, Mirko (Zweitprüfer)
Bachelor Thesis