Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Exposure to substances by use of consumer products
Bitsch, A.; Blume, A.; Delmaar, C.; Hahn, S.; Heiland, A.; Heinemeyer, G.; Klenow, S.; Koch, W.; Neisel, F.; Pirow, R.; Rüdiger, T.; Sommer, Y.; Wiecko, M.
Aufsatz in Buch
2020The life of Hans-Günter Neumann and his contributions to chemical carcinogenesis
Metzler, M.; Bitsch, A.; Degen, G.H.
Zeitschriftenaufsatz
2019Analyses of frequency and sensitivity of affected organs in preclinical studies from RepDose and eTOX database
Moradi Afrapoli, Fatemeh; Escher, Sylvia E.; Bitsch, Annette; Simetska, Nelly
Abstract
2019Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2019Identification of potential emerging chemical risks in food from REACH registered chemicals
Licht, O.; Bitsch, A.; Bohlen, M.L.; Escher, S.E.; Kass, G.; Merten, C.; MacLeod, M.; Noteborn, H.; Schwarz, M.; Oltmanns, J.; Silano, V.
Abstract
2019Identification of potential emerging chemical risks in food from REACH registered chemicals
Bitsch, Annette; Bohlen, M.-L.; Escher, Sylvia E.; Kass, Georges; Licht, Oliver; MacLeod, M.; Merten, C.; Noteborn, H.; Oltmanns, Jan; Schwarz, M.; Silano, V.
Abstract
2019Prediction of adverse effects in preclinical subchronic studies by analysis of adverse effects from shorter-term studies using e.g. the RepDose database
Afrapoli, F.M.; Wehr, M.; Bitsch, A.; Escher, S.E.
Abstract
2019The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
Igl, Bernd-Wolfgang; Bitsch, Annette; Bringezu, Frank; Chang, Steffi; Dammann, Martina; Frötschl, Roland; Harm, Volker; Kellner, Rupert; Krzykalla, Volker; Lott, Jasmin; Nern, Marlies; Pfuhler, Stefan; Queisser, Nina; Schulz, Markus; Sutter, Andreas; Vaas, Lea; Vonk, Richardus; Zellner, Dietmar; Ziemann, Christina
Zeitschriftenaufsatz
2019Towards grouping concepts based on new approach methodologies in chemical hazard assessment: The read-across approach of the EU-ToxRisk project
Escher, Sylvia E.; Kamp, Hennicke; Bennekou, Susanne Hougaard; Bitsch, Annette; Fisher, Ciarán; Gräpel, Rabea; Hengstler, Jan G.; Herzler, Matthias; Knight, Derek; Leist, Marcel; Norinder, Ulf; Ouédraogo, Gladys; Pastor, Manuel; Stuard, Sharon; White, Andrew; Zdrazil, Barbara; Water, Bob van de; Kroese, Dinant
Zeitschriftenaufsatz
2018Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process
Ritter, Detlef; Bitsch, Annette; Elend, Manfred; Schuchardt, Sven; Hansen, Tanja; Brodbeck, Carsten; Knebel, Jan; Fuchs, Anne; Gronewold, Claas; Fautz, Rolf
Zeitschriftenaufsatz
2018Development of a novel scoring system for identifying emerging chemical risks in the food chain
Oltmanns, J.; Licht, O.; Bitsch, Annette; Bohlen, M.-L.; Escher, Sylvia E.; Silano, V.; MacLeod, M.; Serafimova, R.; Kass, G.E.N.; Merten, C.
Zeitschriftenaufsatz
2018Evaluation of the environmental risk assessment procedure according to Directive 2001/18/EC for Gene Modified Organism used as medicinal products
Weigt, Henning; Weber, Elena; Batke, Monika; Schwonbeck, Susanne; Bitsch, Annette
Abstract
2018In depth analysis of selected cosmetic ingredients from the SkinAB database
Schmeinck, Sina; Bitsch, Annette; Genth, Harald
Abstract
2017The potential acute and chronic toxicity of cyfluthrin on the soil model organism, Eisenia fetida
Li, L.; Yang, D.; Song, Y.; Shi, Y.; Huang, B.; Bitsch, A.; Yan, J.
Zeitschriftenaufsatz
2016Analysis of selected substances from the SkinAb database
Schmeinck, S.; Bitsch, A.; Genth, H.
Abstract
2016Endocrine active environmental chemicals in foods
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Endokrin wirksame Umweltchemikalien in Lebensmitteln
Schäfers, C.; Licht, O.; Bitsch, A.
Zeitschriftenaufsatz
2016Innovative strategies to develop chemical categories using a combination of structural and toxicological properties
Batke, Monika; Gütlein, Martin; Partosch, Falko; Gundert-Remy, Ursula; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Seeland, Madeleine; Bitsch, Annette
Zeitschriftenaufsatz
2015Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing
Guerard, M.; Baum, M.; Bitsch, Annette; Eisenbrand, G.; Elhajouji, A.; Epe, B.; Habermeyer, M.; Kaina, B.; Martus, H.J.; Pfuhler, S.; Schmitz, C.; Sutter, A.; Thomas, A.D.; Ziemann, Christina; Froetschl, R.
Zeitschriftenaufsatz
2015Development of chemical categories by optimized clustering strategies
Bitsch, Annette; Batke, Monika; Gundert-Remy, U.; Gütlein, M.; Kramer, S.; Partosch, F.; Seeland, M.
Abstract
2015Evaluation of the toxicity and data gaps of e-cigarette aerosol
May, Martin; Schwarz, Katharina; Koch, Wolfgang; Bitsch, Annette
Abstract
2015Foam spray application of biocides: Investigation into aerosol inhalation exposure
Schwarz, Katharina; Holthenrich, Dagmar; Bissantz, Kathrin; Ehni, Markus; Bitsch, Annette
Zeitschriftenaufsatz
2015Optimization of curation of the dataset with data on repeated dose toxicity
Gundert-Remy, Ursula; Batke, Monika; Bitsch, Annette; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine
Abstract
2015Refinement and enhancement of a database for dermal absorption data
Schmeinck, Sina; Bitsch, Annette; Genth, H.
Abstract
2014Analyzing dermal absorption data of chemicals
Scholz, Roland; Hahn, Stefan; Bitsch, Annette
Zeitschriftenaufsatz, Konferenzbeitrag
2014Correlations between different endpoints in repeated dose toxicity studies: Occurrence of dependent and independent effects at equal dose levels in the RepDose and the "ELINCS" database
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Zeitschriftenaufsatz, Konferenzbeitrag
2014Development of chemical categories by optimized clustering strategies
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Zeitschriftenaufsatz, Konferenzbeitrag
2014Does foam application reduce aerosol formation?
Bitsch, Annette; Schwarz, Katherina; Hahn, Stefan; Ehni, M.; Holthenrich, D.; Koch, W.
Abstract
2014Multi-Label-Classification to predict repeated dose toxicity in the context of REACH
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Zeitschriftenaufsatz, Konferenzbeitrag
2013New strategies for the generation of chemical categories under REACH
Batke, Monika; Gundert-Remy, U.; Helma, C.; Kramer, S.; Kleppe-Nordqvist, Sara; Maunz, A.; Partosch, F.; Seeland, M.; Bitsch, Annette
Zeitschriftenaufsatz, Konferenzbeitrag
2013Regulatorische Anforderungen an Informationen zur dermalen Absorption und deren wirtschaftliche Auswirkungen mit besonderem Fokus auf der Biozid-Zulassung
Scholz, Roland
: Bitsch, Annette (1. Betreuer); Hahn, Stefan (2. Betreuer); Lüning, Ulrich (1. Gutachter); Maser, Edmund (2. Gutachter)
Master Thesis
2013Use of biocides - toxicological effects versus microbiological efficacy
Zwintscher, Ariane; Bitsch, Annette
Zeitschriftenaufsatz, Konferenzbeitrag
2011Development of a strategy for constitution of categories and defining new categories for the end points subacute, subchronical and chronical toxicity to minimize animal testing under REACH
Gundert-Remy, U.; Partosch, F.; Stahlmann, R.; Bitsch, Annette; Weiss, Sara
Konferenzbeitrag, Zeitschriftenaufsatz
2010Emission of biocides from hospitals. Comparing current survey results with European Union default values
Tluczkiewicz, I.; Bitsch, A.; Hahn, S.; Hahn, T.
Zeitschriftenaufsatz
2010Evaluation of inhalation TTC values with the database RepDose
Escher, S.E.; Tluczkiewicz, I.; Batke, M.; Bitsch, A.; Melber, C.; Kroese, E.D.; Buist, H.E.; Mangelsdorf, I.
Zeitschriftenaufsatz
2010Genotoxicity of 1-propanol. Is there a problem?
Licht, O.; Gerdes, H.; Ziemann, C.; Bitsch, A.; Mangelsdorf, I.
Abstract
2009Analysis of target organs in repeated dose toxicity studies
Escher, S.; Batke, M.; Bitsch, A.; Licht, O.; Melber, C.; Simetska, N.; Mangelsdorf, I.
Abstract
2009How valid are "old" repeated dose toxicity studies for chemical risk assessment?
Batke, M.; Escher, S.; Bitsch, A.; Melber, C.; Simetska, N.; Mangelsdorf, I.
Abstract
2009Refinement of TTC values: Identification of outliers in Cramer class 1-3
Tluczkiewicz, I.; Escher, S.; Bitsch, A.; Mangelsdorf, I.
Abstract
2009Toxicological categories - A necessary extension of the chemical category approach
Weiss, S.; Escher, S.; Bitsch, A.; Mangelsdorf, I.
Abstract
2008Breath - a database on occupational exposure limits and local irritation
Batke, M.; Escher, S.; Bitsch, A.; Melber, C.; Simetska, N.; Konieczko, K.; Czerczak, S.; Mangelsdorf, I.
Abstract
2008Influence of study parameters on TTC
Escher, S.; Bitsch, A.; Batke, M.; Melber, C.; Simetska, N.; Mangelsdorf, I.
Konferenzbeitrag, Zeitschriftenaufsatz
2008RepDose and FeDTex. Two databases focusing on systemic toxicity
Bitsch, A.; Escher, S.; Lewin, G.; Melber, C.; Simetska, N.; Mangelsdorf, I.
Konferenzbeitrag, Zeitschriftenaufsatz
2006REPDOSE: A database on repeated dose toxicity studies of commercial chemicals - A multifunctional tool
Bitsch, A.; Jacobi, S.; Melber, C.; Wahnschaffe, U.; Simetska, N.; Mangelsdorf, I.
Zeitschriftenaufsatz
2006Target organs in transgenic mutation assays in comparison to target organs in carcinogenicity studies
Wahnschaffe, U.; Bitsch, A.; Kielhorn, J.; Mangelsdorf, I.
Abstract
2006Transgenic animal mutagenicity assays
Wahnschaffe, U.; Kielhorn, J.; Bitsch, A.; Mangelsdorf, I.
Bericht
2005Mutagenicity testing with transgenic mice. Pt.I: Comparison with the mouse bone marrow micronucleus test
Wahnschaffe, U.; Bitsch, A.; Kielhorn, J.; Mangelsdorf, I.
Zeitschriftenaufsatz
2005Mutagenicity testing with transgenic mice. Pt.II: Comparison with the mouse spot test
Wahnschaffe, U.; Bitsch, A.; Kielhorn, J.; Mangelsdorf, I.
Zeitschriftenaufsatz
2003Development of a database for (Q)SAR in repeated dose toxicity
Bitsch, A.; Wahnschaffe, U.; Simetska, N.; Mangelsdorf, I.
Zeitschriftenaufsatz
2003Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene
Klöhn, P.-C.; Soriano, M.E.; Irwin, W.; Penzo, D.; Scorrano, L.; Bitsch, A.; Neumann, H.-G.; Bernardi, P.
Zeitschriftenaufsatz
2002Etoposide as inducer of apoptotic and genotoxic responses in cells with Different P53 status
Vukicevic, V.; Bitsch, A.; Stopper, H.
Zeitschriftenaufsatz