Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019BI 1026706, a Bradykinin 1 Antagonist, Did Not Reduce Pulmonary Inflammation Upon Segmental Endotoxin Challenge in Healthy Current Smoker Subjects Compared with Placebo
Hohlfeld, Jens M.; Badorrek, Philipp; Faulenbach, Cornelia; Hohl, Kathrin; Litzenburger, T.; Müller, Meike; Sarno, Maria; Seibold, Wolfgang; Gupta, A.
Abstract
2019Molecular Characterization of a Human LPS Challenge Model
Heissig, F.; Litzenburger, T.; Müller, Meike; Wetzel, Kristiane; Hohl, Kathrin; Schmid, Rolf; Seibold, Wolfgang; Sarno, Maria; Gupta, A.; Badorrek, Philipp; Faulenbach, Cornelia; Hohlfeld, Jens M.
Abstract
2019Safety, pharmacokinetics and pharmacodynamics of a novel anti-asthmatic drug, XC8, in healthy probands
Renner, Andreas; Romanova, Julia; Ferko, Boris; Schmutz, Helmut; Nebolsin, Vladimir; Müller, Meike; Badorrek, Philipp; Marth, Katharina; Pohl, Wolfgang
Zeitschriftenaufsatz
2018A computational framework for complex disease stratification from multiple large-scale datasets
Meulder, Bertrand de; Lefaudeux, Diane; Bansal, Aruna T.; Mazein, Alexander; Chaiboonchoe, Amphun; Ahmed, Hassan; Balaur, Irina; Saqi, Mansoor; Pellet, Johann; Ballereau, Stephane; Lemonnier, Nathanaël; Sun, Kai; Pandis, Ioannis; Yang, Xian; Batuwitage, Manohara; Kretsos, Kosmas; Eyll, Jonathan van; Bedding, Alun; Davison, Timothy; Dodson, Paul; Larminie, Christopher; Postle, Anthony; Corfield, Julie; Djukanović, Ratko; Chung, Kian Fan; Adcock, Ian M.; Guo, Yi-Ke; Sterk, Peter J.; Manta, Alexander; Rowe, Anthony; Baribaud, Frédéric; Auffray, Charles; Badorrek, Philipp; Faulenbach, Cornelia; Braun, Armin; Hohlfeld, Jens; Krug, Norbert
Zeitschriftenaufsatz
2018Phase 1 pharmacokinetics and phase 3 efficacy of testosterone nasal gel in subjects with seasonal allergies
Rogol, Alan D.; Tkachenko, Natalia; Badorrek, Philipp; Hohlfeld, Jens M.; Bryson, Nathan
Zeitschriftenaufsatz
2017Specificity and reproducibility of nasal biomarkers in patients with allergic rhinitis after allergen challenge chamber exposure
Badorrek, Philipp; Müller, Meike; Koch, Wolfgang; Hohlfeld, Jens M.; Krug, Norbert
Zeitschriftenaufsatz
2016Safety, efficacy and repeatability of a novel house dust mite allergen challenge technique in the Fraunhofer allergen challenge chamber
Lüer, Katrin; Biller, Heike; Casper, Anja; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, A.; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
Zeitschriftenaufsatz
2015Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis
Badorrek, Philipp; Hohlfeld, Jens M.; Krug, Norbert; Joshi, Abhijeet; Raut, Atul
Zeitschriftenaufsatz
2014Dose-range finding of natural birch pollen exposure in patients with seasonal allergic rhinitis in the Fraunhofer Environmental Challenge Chamber
Lüer, Katrin; Windt, Horst; Schwarz, Katharina; Badorrek, Philipp; Sebastian, Ramona; Haefner, Dietrich; Koch, Wolfgang; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014The effect of controlled exposure to grass pollen in an environmental challenge chamber on dermal symptoms in patients with atopic dermatitis
Heratizadeh, Annice; Badorrek, Philipp; Niebuhr, Margarete; Erpenbeck, Veit Johannes; Lösche, C.; Krug, Norbert; Hohlfeld, Jens Michael; Werfel, Thomas
Abstract
2014Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis
Krug, Norbert; Gupta, Abhy; Badorrek, Philipp; Koennen, Ruediger; Mueller, Meike; Pivovarova, Anna; Hilbert, James; Wetzel, Kristiane; Hohlfeld, Jens M.; Wood, Chester
Zeitschriftenaufsatz
2012CRTH2 antagonist, BI 671800 (BI), reduces nasal symptoms and inhibits nasal cytokines and eosinophils in SAR patients exposed to grass pollen in an environmental challenge chamber (ECC)
Krug, Norbert; Gupta, A.; Badorrek, Philipp; Müller, Meike; Casper, Anja; Pivovarova, A.; Hilbert, J.; Koenen, R.; Hohlfeld, Jens M.; Wood, C.
Abstract
2012Pollen starch granules in bronchial inflammation
Badorrek, Philipp; Dick, Melanie; Emmert, Lorenz; Schaumann, Frank; Koch, Wolfgang; Hecker, Hartmut; Murdoch, Robert; Hohlfeld, Jens M.; Krug, Norbert
Zeitschriftenaufsatz
2012Safety and efficacy of house dust mite allergen challenge in patients with allergic rhinitis using a novel technique for inhalation studies in the Fraunhofer environmental challenge chamber
Lueer, Katrin; Biller, Heike; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, Armin; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
Abstract