Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019The clinical course of idiopathic pulmonary fibrosis and its association to quality of life over time
Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohé, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Gläser, S.; Kahn, N.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Oqueka, T.; Frankenberger, M.; Behr, J.
Journal Article
2019Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM)
Vogel-Claussen, J.; Schönfeld, C.-O.; Kaireit, T.F.; Voskrebenzev, A.; Czerner, C.P.; Renne, J.; Tillmann, H.-C.; Berschneider, K.; Hiltl, S.; Bauersachs, J.; Welte, T.; Hohlfeld, J.M.
Journal Article
2018Comparison of quantitative regional ventilation‐weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients
Kaireit, Till F.; Gutberlet, Marcel; Voskrebenzev, Andreas; Freise, Julia; Welte, Tobias; Hohlfeld, Jens M.; Wacker, Frank; Vogel-Claussen, Jens
Journal Article
2018Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): A double-blind, randomised, crossover, placebo-controlled, single-centre trial
Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias
Journal Article
2018Free-breathing dynamic (19)F gas MR imaging for mapping of regional lung ventilation in patients with COPD
Gutberlet, Marcel; Kaireit, Till F.; Voskrebenzev, Andreas; Lasch, Florian; Freise, Julia; Welte, Tobias; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Journal Article
2018Lobe-wise assessment of lung volume and density distribution in lung transplant patients and value for early detection of bronchiolitis obliterans syndrome
Dettmer, S.; Suhling, H.; Klingenberg, I.; Otten, O.; Kaireit, T.; Fuge, J.; Kuhnigk, J.M.; Gottlieb, J.; Haverich, A.; Welte, T.; Wacker, F.; Vogel-Claussen, J.; Shin, H.O.
Journal Article
2018Lung deflation and improvement of cardiac end-diastolic volumes with indacaterol/glycopyrronium reduce dyspnea and improve health status in hyperinflated COPD patients: The CLAIM study
Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias
Abstract
2018Lungenentblähung mit Indacaterol/Glycopyrronium verbessert die kardiale Funktion bei COPD Patienten: Die CLAIM Studie
Hohlfeld, Jens; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias
Abstract
2018Lungenentblähung mit Indacaterol/Glycopyrronium verbessert die kardiale Funktion von COPD Patienten: Die CLAIM Studie
Hohlfeld, Jens M.; Vogel-Claussen, Jens; Biller, Heike; Berliner, Dominik; Berschneider, Korbinian; Tillmann, Hanns-Christian; Hiltl, Simone; Bauersachs, Johann; Welte, Tobias
Abstract
2017Health related quality of life in patients with idiopathic pulmonary fibrosis in clinical practice: insights-IPF registry
Kreuter, M.; Swigris, J.; Pittrow, D.; Geier, S.; Klotsche, J.; Prasse, A.; Wirtz, H.; Koschel, D.; Andreas, S.; Claussen, M.; Grohe, C.; Wilkens, H.; Hagmeyer, L.; Skowasch, D.; Meyer, J.F.; Kirschner, J.; Glaser, S.; Herth, F.J.F.; Welte, T.; Neurohr, C.; Schwaiblmair, M.; Held, M.; Bahmer, T.; Frankenberger, M.; Behr, J.
Journal Article
2017Influence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome
Engel, M.; Endesfelder, D.; Schloter-Hai, B.; Kublik, S.; Granitsiotis, M.S.; Boschetto, P.; Stendardo, M.; Barta, I.; Dome, B.; Deleuze, J.F.; Boland, A.; Müller-Quernheim, J.; Prasse, A.; Welte, T.; Hohlfeld, J.; Subramanian, D.; Parr, D.; Gut, I.G.; Greulich, T.; Koczulla, A.R.; Nowinski, A.; Gorecka, D.; Singh, D.; Gupta, S.; Brightling, C.E.; Hoffmann, H.; Frankenberger, M.; Hofer, T.P.; Burggraf, D.; Heiss-Neumann, M.; Ziegler-Heitbrock, L.; Schloter, M.; Castell, W. zu
Journal Article
2017Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function
Waschki, Benjamin; Watz, Henrik; Holz, Olaf; Magnussen, Helgo; Olejnicka, Beata; Welte, Tobias; Rabe, Klaus F.; Janciauskiene, Sabina
Journal Article
2017Recommended practices for wind farm data collection and reliability assessment for O&M optimization
Hahn, B.; Welte, T.; Faulstich, S.; Bangalore, R.; Boussion, C.; Harrison, K.; Meguelanez-Martin, E.; O'Connor, F.; Pettersson, L.; Soraghan, C.; Stock-Williams, C.; Dalsgaard Sørensen, J.; Bussel, G. van; Vatn, J.
Journal Article, Conference Paper
2016α1-Antitrypsin (a1at) serum levels as marker of systemic inflammation in non-A1at-deficient patients with COPD
Waschki, B.; Kirsten, A.-M.; Holz, O.; Meyer, T.; Lichtinghagen, R.; Rabe, K.F.; Magnussen, H.; Welte, T.; Watz, H.; Janciauskiene, S.
Abstract
2016Angiopoietin-like protein 4 and cardiovascular function in COPD
Waschki, Benjamin; Kirsten, Anne-Marie; Holz, Olaf; Meyer, T.; Lichtinghagen, R.; Rabe, K.F.; Magnussen, Helgo; Welte, T.; Watz, H.; Janciauskiene, S.
Journal Article
2016Data collection and reliability assessment for O&M optimization of wind turbines
Hahn, B.; Welte, T.; Bussel, G. van
Presentation
2016Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography
Subramanian, Deepak R.; Gupta, Sumit; Burggraf, Dorothe; Silberberg, Suzan J. vom; Heimbeck, Irene; Heiss-Neumann, Marion S.; Haeussinger, Karl; Newby, Chris; Hargadon, Beverley; Raj, Vimal; Singh, Dave; Kolsum, Umme; Hofer, Thomas P.; Al-Shair, Khaled; Luetzen, Niklas; Prasse, Antje; Müller-Quernheim, Joachim; Benea, Giorgio; Leprotti, Stefano; Boschetto, Piera; Gorecka, Dorota; Nowinski, Adam; Oniszh, Karina; Castell, Wolfgang zu; Hagen, Michael; Barta, Imre; Döme, Balazs; Strausz, Janos; Greulich, Timm; Vogelmeier, Claus; Koczulla, Andreas R.; Gut, Ivo; Hohlfeld, Jens; Welte, Tobias; Lavae-Mokhtari, Mahyar; Ziegler-Heitbrock, Loems; Brightling, Christopher; Parr, David G.
Journal Article
2016Steroid treatment reduces allergic airway inflammation and does not alter the increased numbers of dendritic cells and calcitonin gene-related peptide-expressing neurons in airway sensory ganglia
Le, Duc Dung; Funck, Ulrike; Wronski, Sabine; Heck, Sebastian; Tschernig, Thomas; Bischoff, Markus; Sester, Martina; Herr, Christian; Bals, Robert; Welte, Tobias; Braun, Armin; Dinh, Quoc Thai
Journal Article
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Journal Article
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Abstract
2014Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia
Le, D.D.; Rochlitzer, S.; Fischer, A.; Heck, S.; Tschernig, T.; Sester, M.; Bals, R.; Welte, T.; Braun, A.; Dinh, Q.T.
Journal Article
2014Allergische Atemwegsentzündung induziert eine Zunahme von Dendritischen Zellen in den Atemwegsganglien der Maus
Le, Duc Dung; Rochlitzer, Sabine; Heck, Sebastian; Bals, Robert; Braun, Armin; Welte, Tobias; Dinh, Quoc Thai
Abstract
2014Automated characterization of breast lesions imaged with an ultrafast DCE-MR protocol
Platel, B.; Mus, R.; Welte, T.; Karssemeijer, N.; Mann, R.
Journal Article
2014Neuronale Plastizität in NGF-transgenen Mäusen bei allergischen Atemwegentzündungen
Dinh, Quoc Thai; Quarcoo, David; Braun, Armin; Welte, Tobias; Bals, Robert; Fischer, A.
Abstract
2014Veränderung von MHC-II positiven Zellen der Atemwegsganglien bei chronischem Hausstaubmilben-Mausmodell und HRV1B Infektion
Funck, Ulrike; Le, Duc Dung; Rochlitzer, Sabine; Heck, Sebastian; Bals, Robert; Braun, Armin; Welte, Tobias; Dinh, Quoc Thai
Abstract
2013Anti-inflammatory and immunomodulatory properties of alpha1-antitrypsin without inhibition of elastase
Jonigk, Danny; Al-Omari, Mariam; Maegel, Lavinia; Müller, Meike; Izykowski, Nicole; Hong, Jaewoo; Hong, Kwangwon; Kim, Soo-Hyun; Dorsch, Martina; Mahadeva, Riva; Laenger, Florian; Kreipe, Hans; Braun, Armin; Shahaf, Galit; Lewis, Eli C.; Welte, Tobias; Dinarello, Charles A.; Janciauskiene, Sabina
Journal Article
2013Expression of VPAC1 in a murine model of allergic asthma
Lauenstein, Hans D.; Quarcoo, David; Welte, Tobias; Braun, Armin; Groneberg, David A.
Journal Article
2012Allergic airway inflammation in mice deficient for the antigen-processing protease cathepsin E
Pilzner, C.; Bühling, F.; Reinheckel, T.; Chwieralski, C.; Rathinasamy, A.; Lauenstein, H.-D.; Wex, T.; Welte, T.; Braun, A.; Groneberg, D.A.
Journal Article
2012Bacterial infection triggers exacerbation of established pulmonary fibrosis in mice: Impact on lung protective immunity
Ueberberg, Bianca; Janze, Ann-Kathrin; Steinwede, Kathrin; Maus, Regina; Magel, Lavinia; Hoymann, Heinz-Gerd; Braun, Armin; Langer, Florian; Jonigk, Danny; Kolb, Martin; Gauldie, Jack; Welte, Tobias; Maus, Ulrich A.
Abstract
2012Cathepsin G and neutrophil elastase contribute to lung protective immunity against mycobacterial infections in mice
Steinwede, Kathrin; Maus, Regina; Bohling, Jennifer; Voedisch, Sabrina; Braun, Armin; Ochs, Matthias; Schmiedl, Andreas; Walter, Kerstin; Bange, Franz; Welte, Tobias; Ehlers, Stefan; Maus, Ulrich A.
Abstract
2012Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice
Steinwede, Kathrin; Maus, Regina; Bohling, Jennifer; Voedisch, Sabrina; Braun, Armin; Ochs, Matthias; Schmiedl, Andreas; Länger, Florian; Gauthier, Francis; Roes, Jürgen; Welte, Tobias; Bange, Franz C.; Niederweis, Michael; Bühling, Frank; Maus, Ulrich A.
Journal Article
2012The EvA study: Aims and strategy
Ziegler-Heitbrock, L.; Frankenberger, M.; Heimbeck, I.; Burggraf, D.; Wjst, M.; Häussinger, K.; Brightling, C.; Gupta, S.; Parr, D.; Subramanian, D.; Singh, D.; Kolsum, U.; Boschetto, P.; Potena, A.; Gorecka, D.; Nowinski, A.; Barta, I.; Döme, B.; Strausz, J.; Greulich, T.; Vogelmeier, C.; Bals, R.; Hohlfeld, J.M.; Welte, T.; Venge, P.; Gut, I.; Boland, A.; Olaso, R.; Hager, J.; Hiemstra, P.; Rabe, K.F.; Unmüßig, M.; Müller-Quernheim, J.; Prasse, A.
Journal Article
2012Neuro-immune interaction in allergic airway inflammation: Expression and function of dendritic cells in sensory airway ganglia neurons
Le, Dung D.; Rochlitzer, Sabine; Funck, Ulrke; Suhling, Hendrik; Braun, Armin; Welte, Tobias; Din, Quoc Thai
Abstract
2011Functional role of lysosomal proteases in allergic airway inflammation
Pilzner, C.
: Groneberg, D.; Welte, T.; Braun, A.
Dissertation
2011Neuronale Kontrolle bei chronisch entzündlichen und obstruktiven Lungenerkrankungen wie Asthma bronchiale und COPD
Dinh, Q.T.; Suhling, H.; Fischer, A.; Braun, Armin; Welte, Tobias
Journal Article
2011Pituitary adenylate cyclase-activating peptide receptor 1 mediates anti-inflammatory effects in allergic airway inflammation in mice
Lauenstein, H.D.; Quarcoo, D.; Plappert, L.; Schleh, C.; Nassimi, M.; Pilzner, C.; Rochlitzer, S.; Brabet, P.; Welte, T.; Hoymann, H.G.; Krug, N.; Müller, M.; Lerner, E.A.; Braun, A.; Groneberg, D.A.
Journal Article
2010Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-beta 1
Rodt, T.; Falck, C. von; Dettmer, S.; Halter, R.; Maus, R.; Ask, K.; Kolb, M.; Gauldie, J.; Länger, F.; Hoy, L.; Welte, T.; Galanski, M.; Maus, U.A.; Borlak, J.
Journal Article
2009Bronchial epithelial cells as a new source for differential transcriptome analysis after lung transplantation
Skawran, B.; Dierich, M.; Steinemann, D.; Hohlfeld, J.; Haverich, A.; Schlegelberger, B.; Welte, T.; Neuhoff, N. von
Journal Article
2009Expression, localisation and functional implications of the transporter protein PEPT2 in the upper respiratory tract
Quarcoo, D.; Fischer, T.C.; Heppt, W.; Lauenstein, H.-D.; Pilzner, C.; Welte, T.; Groneberg, D.A.
Journal Article
2009Gesundheitliche Effekte der Feinstaubbelastung aktueller wissenschaftlicher Kenntnisstand
Groneberg, D.A.; Morfeld, P.; Kraus, T.; Köhler, D.; Krug, N.; Magnussen, H.; Nowak, D.; Rabe, K.F.; Schultze-Werninghaus, G.; Schulz, H.; Teschler, H.; Vogelmeier, C.; Wagner, U.; Welte, T.; Voshaar, T.; Witt, C.
Journal Article
2009Role of pituitary adenylate cyclase-peptide receptor 1 in a murine model of allergic asthma
Lauenstein, H.; Plappert, L.; Rochlitzer, S.; Pilzner, C.; Welte, T.; Krug, N.; Groneberg, D.; Braun, A.
Abstract
2008Effects of specific pituitary adenylate cyclase activating peptide receptor 1 agonist maxadilan in a murine model of allergic asthma
Lauenstein, H.; Plappert, L.; Braun, A.; Krug, N.; Welte, T.; Fuchs, B.; Groneberg, D.
Abstract
2008Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
Srivastava, M.; Steinwede, K.; Kiviranta, R.; Morko, J.; Hoymann, H.-G.; Länger, F.; Buhling, F.; Welte, T.; Maus, U.A.
Journal Article
2008Pneumococcal vaccines: Mechanism of action, impact on epidemiology and adaption of the species
Pletz, M.W.; Maus, U.; Krug, N.; Welte, T.; Lode, H.
Journal Article
2008Pneumokokkenimpfung: Konjugatimpfstoff induziert Herdenimmunität und reduziert Antibiotikaresistenz
Pletz, M.W.; Maus, U.; Hohlfeld, J.M.; Lode, H.; Welte, T.
Journal Article
2008Die Prävalenz der chronisch obstruktiven Lungenerkrankung (COPD) in Deutschland
Geldmacher, H.; Biller, H.; Herbst, A.; Urbanski, K.; Allison, M.; Buist, A.S.; Hohlfeld, J.M.; Welte, T.
Journal Article
2007Function of pulmonary PACl receptor in a murine model of allergic asthma
Lauenstein, H.-D.; Plappert, L.; Quarcoo, D.; Fuchs, B.; Pilzner, C.; Fischer, A.; Krug, N.; Welte, T.; Braun, A.; Groneberg, D.A.
Abstract
2006Pathomechanismen der chronisch-obstruktiven Lungenerkrankung (COPD)
Glaab, T.; Hohlfeld, J.M.; Jörres, R.A.; Krug, N.; Welte, T.
Journal Article