Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2017MicroRNA-21 versus microRNA-34: Lung cancer promoting and inhibitory microRNAs analysed in silico and in vitro and their clinical impact
Kunz, Meik; Göttlich, Claudia; Walles, Thorsten; Nietzer, Sarah; Dandekar, Gudrun; Dandekar, Thomas
Journal Article
2017Non-coding RNAs in lung cancer: Contribution of bioinformatics analysis to the development of non-invasive diagnostic tools
Kunz, M.; Wolf, B.; Schulze, H.; Atlan, D.; Walles, T.; Walles, H.; Dandekar, T.
Journal Article
2016A combined 3D tissue engineered in Vitro/in silico lung tumor model for predicting drug effectiveness in specific mutational backgrounds
Göttlich, Claudia; Müller, Lena C.; Kunz, Meik; Schmitt, Franziska; Walles, Heike; Walles, Thorsten; Dandekar, Thomas; Dandekar, Gudrun; Nietzer, Sarah L.
Journal Article
2016Human organotypic lung tumor models: Suitable for preclinical 18F-FDG PET-imaging
Fecher, David; Hofmann, Elisabeth; Buck, Andreas; Bundschuh, Ralph; Nietzer, Sarah; Dandekar, Gudrun; Walles, Thorsten; Walles, Heike; Lückerath, Katharina; Steinke, Maria
Journal Article
2016Individualized drug response predictions based on a combined in silico and in vitro lung cancer model on a biological scaffold
Göttlich, C.; Kunz, M.; Walles, T.; Walles, H.; Dandekar, T.; Dandekar, G.; Nietzer, S.
Abstract
2015Host-integration of a tissue-engineered airway patch: Two-year follow-up in a single patient
Steinke, Maria; Dally, Iris; Friedel, Godehard; Walles, Heike; Walles, Thorsten
Journal Article
2015Respiratory system
Fecher, David; Steinke, Maria; Walles, Thorsten
Book Article
2014An engineered 3D human airway mucosa model based on an SIS scaffold
Steinke, M.; Gross, R.; Walles, H.; Gangnus, R.; Schütze, K.; Walles, T.
Journal Article
2013Biomedizin in der Thoraxchirurgie: Eine Standortbestimmung
Leistner, M.; Steinke, M.; Walles, T.
Journal Article
2013A human airway mucosa tissue model to investigate whooping cough
Steinke, M.; Gross, R.; Bauer, S.; Walles, T.; Walles, H.
Journal Article
2012Engineering of fibrillar decorin matrices for a tissue-engineered trachea
Hinderer, S.; Schesny, M.; Bayrak, A.; Ibold, B.; Hampel, M.; Walles, T.; Stock, U.A.; Seifert, M.; Schenke-Layland, K.
Journal Article
2012Tissue Engineering: Menschliche Gewebe aus dem Labor
Schanz, J.; Walles, H.; Walles, T.
Journal Article
2011In vitro development of a vascularised tracheal patch to restore airway defects after resection
Dally, I.; Schandar, M.; Linke, K.; Pusch, J.; Walles, T.; Walles, H.
Abstract
2011Tracheobronchial bio-engineering: Biotechnology fulfilling unmet medical needs
Walles, T.
Journal Article
2010Impact of neo-adjuvant radiochemotherapy on bronchial tissue viability
Hampel, M.; Dally, I.; Walles, T.; Steger, V.; Veit, S.; Kyriss, T.; Friedel, G.
Journal Article
2010Neoadjuvant chemoradiation in NSCLC: Influence on bronchus vitality and postoperative complication risk
Walles, T.; Hampel, M.; Dally, I.; Steger, V.; Friedel, G.
Abstract
2009Europe's advanced therapy medicinal products: Chances and challenges. Editorial
Mertsching, H.; Walles, T.
Journal Article
2009Experimental tracheal patching using extracellular matrix scaffolds
Schanz, J.; Hampel, M.; Mertsching, H.; Walles, T.
Journal Article
2009Generation and transplantation of an autologous vascularized bioartificial human tissue
Mertsching, H.; Schanz, J.; Steger, V.; Schandar, M.; Schenk, M.; Hansmann, J.; Dally, I.; Friedel, G.; Walles, T.
Journal Article
2009Regenerative Medizin in Deutschland: Großer Innovationssektor trifft auf hohe Hürden
Mertsching, H.; Walles, T.
Journal Article
2008Clinical tracheal replacement: transplantation, bioprostheses and artificial grafts
Steger, V.; Hampel, M.; Trick, I.; Müller, M.; Walles, T.
Journal Article
2008Vascularized engineered transplants for reconstructive surgery: Implant generation and first clinical experiences
Walles, T.; Schanz, J.; Schandar, M.; Steger, V.; Friedel, G.; Mertsching, H.
Conference Paper
2007Engineered liver-like tissue on a capillarized matrix for applied research
Linke, K.; Schanz, J.; Hansmann, J.; Walles, T.; Brunner, H.; Mertsching, H.
Journal Article
2007Generation of a vascularized biomatrix as a scaffold for tissue engineering
Schanz, J.; Walles, T.; Mertsching, H.
Conference Paper, Journal Article
2007The potential of bioartificial tissues in oncology research and treatment
Walles, T.; Weimer, M.; Linke, K.; Michaelis, J.; Mertsching, H.
Journal Article
2007Strategies for scaffold vascularization in tissue engineering
Walles, T.; Mertsching, H.
Book Article
2006Density of dendritic cells in the human tracheal mucosa is age dependent and site specific
Tschernig, T.; Vries, V.C. de; Debertin, A.S.; Braun, A.; Walles, T.; Traub, F.; Pabst, R.
Journal Article
2006Generation of a bioartificial fibromuscular tissue with autoregenerative capacities for surgical reconstruction
Biancosino, C.; Zardo, P.; Walles, T.; Wildfang, I.; Macchiarini, P.; Mertsching, H.
Journal Article
2006Vaskularisierte Trägersysteme für in vitro Testsysteme
Mertsching, H.; Hansmann, J.; Schanz, J.; Linke, K.; Brenner, M.; Michaelis, J.; Walles, T.
Conference Paper
2005Bioartifizielles, primaer vaskularisiertes Testgewebe fuer pharmakologische Testverfahren, Verfahren zu dessen Herstellung und Testverfahren unter dessen Verwendung sowie Bioreaktor zur Durchfuehrung der Verfahren
Walles, T.D.
Patent
2005Biological vascularized matrix for bladder tissue engineering: Matrix preparation, reseeding technique and short-term implantation in a porcine model
Schultheiss, D.; Gabouev, A.I.; Cebotari, S.; Tudorache, I.; Walles, T.; Schlote, N.; Wefer, J.; Kaufmann, P.M.; Haverich, A.; Jonas, U.; Stief, C.G.; Mertsching, H.
Journal Article
2005Endothelialization and functional neointima on vascular grafts in humans: Reply
Walles, T.; Mertsching, H.
Journal Article
2005Engineering of a vascularized scaffold for artificial tissue and organ generation
Mertsching, H.; Walles, T.; Hofmann, M.; Schanz, J.; Knapp, W.H.
Journal Article
2005Neointima in vascular prostheses: The jury is still out: Reply
Walles, T.; Mertsching, H.
Journal Article
2005Tissue remodeling in a bioartificial fibromuscular patch following transplantation in a human
Walles, T.; Biancosino, C.; Zardo, P.; Macciarini, P.; Gottlieb, J.; Mertsching, H.
Journal Article
2004Expansion of chondrocytes in a three-dimensional matrix for tracheal tissue engineering
Walles, T.; Giere, B.; Macchiarini, P.; Mertsching, H.
Journal Article
2004Experimental generation of a tissue-engineered functional and vascularized trachea
Walles, T.; Giere, B.; Hofmann, M.; Schanz, J.; Hofmann, F.; Mertsching, H.; Macchiarini, P.
Journal Article
2004Expression of epidermal growth-factor receptor in lymphangiomatosis: A new therapeutic target?
Mertsching, H.; Walles, T.; Bakker, G.; Wildfang, I.; Macchiarini, P.
Journal Article
2004First human transplantation of a bioengineered airway tissue
Macchiarini, P.; Walles, T.; Biancosino, C.; Mertsching, H.
Journal Article
2004Functional neointima characterization of vascular prostheses in human
Walles, T.; Görler, H.; Puschmann, C.; Mertsching, H.
Journal Article
2004Replacement of the trachea with an autologous aortic graft
Mertsching, H.; Walles, T.; Macchiarini, P.
Journal Article