Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2011Discrepancy between high clastogenic activity of trans-beta-nitrostyrene in vitro and lack in carcinogenicity might be related to inactivating metabolism and its high reactivity towards thiol groups
Ziemann, Christina; Apitius, Florian; Elend, Manfred; Baumgartner, S.; Volk, J.; Ritter, Detlef; Steinfelder, H.J.; Schuchardt, Sven
Conference Paper, Journal Article
2010Comparative mechanistical investigations on the genotoxic potential of nitrovinyluracil derivatives
Heinemann, D.; Ritter, D.; Kasper, C.; Eger, K.; Steinfelder, H.J.; Ziemann, C.
Abstract
2007Generation of reactive oxygen species may participate in the clastogenic and mutagenic activity of trans-beta-nitrostvrene
Ziemann, C.; Rahmer, H.; Leyhausen, G; Steinfelder, H.J.; Volk, J.
Conference Paper, Journal Article
2006An intact C=C bond in the vinyl side chain is required for the pro-apoptotic effect of nitrostyrene and its derivatives
Steinfelder, H.J.; Quentin, I.; Leonhardt, U.; Krause, D.; Eger, K.; Ziemann, C.
Abstract
2006Involvement of topoisomerase II inhibition in clastogenic activity of trans-b-Nitrostyrene
Ziemann, C.; Krauß, S.; Brockmeyer, H.; Leonhardt, U.; Steinfelder, H.J.
Abstract
2006The role of Prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures
Ziemann, C.; Riecke, A.; Rüdell, G.; Oetjen, E.; Steinfelder, H.J.; Lass, C.; Kahl, G.F.; Hirsch-Ernst, K.I.
Journal Article
2005Complex clastogenic activity of trans-ß-nitrostyrene in vitro is related to cellular glutathione content
Ziemann, C.; Kaap, S.; Kleemann, I.; Steinfelder, H.J.
Conference Paper, Journal Article
2004Contribution of the EP4-receptor, PKA and CREB to intrinsic mdr1b overexpression in rat hepatocyte cultures
Ziemann, C.; Rüdell, G.; Riecke, A.; Steinfelder, H.J.; Oetjen, E.; Hirsch-Ernst, K.I.
Journal Article, Conference Paper
2004Early DNA damage apparently con tributes to the pro-apoptotic effect of nitrostyrene derivatives in normal and BCL-XL over-expressing HL60 cells
Ziemann, C.; Kleemann, I.; Eger, K.; Steinfelder, H.J.
Conference Paper, Journal Article
2004The EP4 receptor and PKA-dependent modification of CRE binding proteins participate in intrinsic mdr1b gene activation in primary rat hepatocyte cultures
Ziemann, C.; Rüdell, G.; Riecke, A.; Steinfelder, H.J.; Oetjen, E.; Hirsch-Ernst, K.I.; Kahl, G.F.
Journal Article, Conference Paper