Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Enhanced performance of next-generation sequencing diagnostics compared with standard of care microbiological diagnostics in patients suffering from septic shock
Grumaz, Silke; Grumaz, Christian; Vainshtein, Yevhen; Stevens, Philip; Glanz, Karolina; Decker, Sebastian O.; Hofer, Stefan; Weigand, Markus A.; Brenner, Thorsten; Sohn, Kai
Journal Article
2019New approaches for the detection of invasive fungal diseases in patients following liver transplantation - results of an observational clinical pilot study
Decker, Sebastian O.; Krüger, Albert; Wilk, Henryk; Grumaz, Silke; Vainshtein, Yevhen; Schmitt, Felix C.F.; Uhle, Florian; Bruckner, Thomas; Zimmermann, Stefan; Mehrabi, Arianeb; Mieth, Markus; Weiss, Karl Heinz; Weigand, Markus A.; Hofer, Stefan; Sohn, Kai; Brenner, Thorsten
Journal Article
2019Obstructed defecation - an enteric neuropathy? An exploratory study of patient samples
Kim, M.; Rosenbaum, C.; Schlegel, N.; Grumaz, C.; Sohn, K.; Isbert, C.; Walles, H.; Metzger, M.
Journal Article
2018Genetic repertoires of anaerobic microbiomes driving generation of biogas
Grohmann, Anja; Vainshtein, Yevhen; Euchner, Ellen; Grumaz, Christian; Bryniok, Dieter; Rabus, Ralf; Sohn, Kai
Journal Article
2018Localization and functional characterization of the pathogenesis-related proteins Rbe1p and Rbt4p in Candida albicans
Bantel, Yannick; Darwiche, Rabih; Rupp, Steffen; Schneiter, Roger; Sohn, Kai
Journal Article
2018Microbiome dynamics and adaptation of expression signatures during methane production failure and process recovery
Grohmann, A.; Fehrmann, S.; Vainshtein, Y.; Haag, N.L.; Wiese, F.; Stevens, P.; Naegele, H.-J.; Oechsner, H.; Hartsch, T.; Sohn, K.; Grumaz, C.
Journal Article
2018Next-generation sequencing diagnostics of bacteremia in sepsis (Next GeneSiS-Trial): Study protocol of a prospective, observational, noninterventional, multicenter, clinical trial
Brenner, Thorsten; Decker, Sebastian O.; Grumaz, Silke; Stevens, Philip; Bruckner, Thomas; Schmoch, Thomas; Pletz, Mathias W.; Bracht, Hendrik; Hofer, Stefan; Marx, Gernot; Weigand, Markus A.; Sohn, Kai
Journal Article
2018A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s
Worsch, Anne; Eggimann, Fabian K.; Girhard, Marco; Bühler, Clemens J. von; Tieves, Florian; Czaja, Rico; Vogel, Andreas; Grumaz, Christian; Sohn, Kai; Lütz, Stephan; Kittelmann, Matthas; Urlacher, Vlada B.
Journal Article
2017Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion
Mailänder-Sánchez, D.; Braunsdorf, C.; Grumaz, C.; Müller, C.; Lorenz, S.; Stevens, P.; Wagener, J.; Hebecker, B.; Hube, B.; Bracher, F.; Sohn, K.; Schaller, M.
Journal Article
2017Central role for dermal fibroblasts in skin model protection against Candida albicans
Kühbacher, A.; Henkel, H.; Stevens, P.; Grumaz, C.; Finkelmeier, D.; Burger-Kentischer, A.; Sohn, K.; Rupp, S.
Journal Article
2017Correction to: Dual transcriptome of the immediate neutrophil and Candida albicans interplay
Niemiec, M.J.; Grumaz, C.; Ermert, D.; Desel, C.; Shankar, M.; Lopes, J.P.; Mills, I.G.; Stevens, P.; Sohn, K.; Urban, C.F.
Journal Article
2017Draft genome sequence of Pseudonocardia autotrophica strain DSM 43083, an efficient producer of peroxidases for lignin modification
Grumaz, Christian; Rais, Dominik; Kirstahler, Philipp; Vainshtein, Yevhen; Rupp, Steffen; Zibek, Susanne; Sohn, Kai
Journal Article
2017Draft genome sequences of three Actinobacteria strains presenting new candidate organisms with high potentials for specific P450 cytochromes
Grumaz, C.; Vainshtein, Y.; Kirstahler, P.; Luetz, S.; Kittelmann, M.; Schroer, K.; Eggimann, F.K.; Czaja, R.; Vogel, A.; Hilberath, T.; Worsch, A.; Girhard, M.; Urlacher, V.B.; Sandberg, M.; Sohn, K.
Journal Article
2017Dual transcriptome of the immediate neutrophil and Candida albicans interplay
Niemiec, M.J.; Grumaz, C.; Ermert, D.; Desel, C.; Shankar, M.; Lopes, J.P.; Mills, I.G.; Stevens, P.; Sohn, K.; Urban, C.F.
Journal Article
2017Immune cell-supplemented human skin model for studying fungal infections
Kühbacher, Andreas; Sohn, Kai; Burger-Kentischer, Anke; Rupp, Steffen
Book Article
2017Immune-response patterns and next generation sequencing diagnostics for the detection of mycoses in patients with septic shock - results of a combined clinical and experimental investigation
Decker, S.O.; Sigl, A.; Grumaz, C.; Stevens, P.; Vainshtein, Y.; Zimmermann, S.; Weigand, M.A.; Hofer, S.; Sohn, K.; Brenner, T.
Journal Article
2017Method and device for nucleic acid based diagnostic approaches including the determination of a deviant condition, especially a health condition and/or pathogenic condition of a sample
Stevens, Philip; Sohn, Kai; Grumaz, Silke; Haeseler, Arndt von
Patent
2017The molecular blueprint of a fungus by next-generation sequencing (NGS)
Grumaz, Christian; Kirstahler, Philipp; Sohn, Kai
Book Article
2016Advanced green biorefining: Effects of ensiling treatments on lactic acid production, microbial activity and supplementary methane formation of grass and rye
Haag, Nicola Leonard; Grumaz, Christian; Wiese, Franziska; Kirstahler, Philipp; Merkle, Wolfgang; Nägele, Hans-Joachim; Sohn, Kai; Jungbluth, Thomas; Oechsner, Hans
Journal Article
2016A method to identify protein antigens of Dermanyssus gallinae for the protection of birds from poultry mites
Makert, Gustavo R.; Vorbrüggen, Susanne; Krautwald-Junghanns, Maria-Elisabeth; Voss, Matthias; Sohn, Kai; Buschmann, Tilo; Ulbert, Sebastian
Journal Article
2016Next-generation sequencing diagnostics of bacteremia in septic patients
Grumaz, Silke; Stevens, Philip; Grumaz, Christian; Decker, Sebastian O.; Weigand, Markus A.; Hofer, Stefan; Brenner, Thorsten; Haeseler, Arndt von; Sohn, Kai
Journal Article
2016Transcriptomics and physiological analyses reveal co-ordinated alteration of metabolic pathways in Jatropha curcas drought tolerance
Sapeta, Helena; Lourenco, Tiago; Lorenz, Stefan; Grumaz, Christian; Kirstahler, Philipp; Barros, Pedro M.; Costa, Joaquim Miguel; Sohn, Kai; Oliveira, M. Margarida
Journal Article
2015Anaerobe Batch-Fermentation mit Mais- und Amaranthsilagen: Biogasproduktion und molekulare Charakterisierung mikrobieller Gemeinschaften
Kempter-Regel, Brigitte; Grumaz, Christian; Wiese, Franziska; Scherge, Katharina; Birk, Carolin; Schließmann, Ursula; Stevens, Philip; Sohn, Kai; Bryniok, Dieter
Conference Paper
2015Draft genome sequence of Amantichitinum ursilacus IGB-41, a new chitin-degrading bacterium
Kirstahler, Philipp; Günther, Michael; Grumaz, Christian; Lindemann, Elena; Rupp, Steffen; Zibek, Susanne; Sohn, Kai
Journal Article
2015Stoffwechselanalysen in komplexen mikrobiellen Biozönosen
Stevens, P.; Grumaz, C.; Wiese, F.; Sohn, K.
Journal Article
2015The transcriptomic profile of Pseudozyma aphidis during production of mannosylerythritol lipids
Günther, M.; Grumaz, C.; Lorenz, S.; Stevens, P.; Lindemann, E.; Hirth, T.; Sohn, K.; Zibek, S.; Rupp, S.
Journal Article
2015Transcriptomic profiling of Pseudozyma aphidis during mannosylerythritol lipid synthesis
Günther, Michael; Grumaz, Christian; Lorenz, Stefan; Stevens, Philip; Lindemann, Elena; Hirth, Thomas; Sohn, Kai; Zibek, Susanne; Rupp, Steffen
Abstract
2014Genome sequence of the basidiomycetous fungus Pseudozyma aphidis DSM70725, an efficient producer of biosurfactant mannosylerythritol lipids
Lorenz, Stefan; Günther, Michael; Grumaz, Christian; Rupp, Steffen; Zibek, Susanne; Sohn, Kai
Journal Article
2014An in vivo photo-cross-linking approach reveals a homodimerization domain of Aha1 in S. cerevisiae
Berg, M.; Michalowski, A.; Palzer, S.; Rupp, S.; Sohn, K.
Journal Article
2013Characterization of the protective and immunregulatory activity of probiotic lactobacilli in mucosal Candidiasis
Mailander-Sanchez, D.; Wagener, J.; Braunsdorf, C.; Grumaz, C.; Lorenz, S.; Sohn, K.; Wehkamp, J.; Schaller, M.
Conference Paper, Journal Article
2013An expanded genetic code in Candida albicans to study protein-protein interactions in vivo
Palzer, S.; Bantel, Y.; Kazenwadel, F.; Berg, M.; Rupp, S.; Sohn, K.
Journal Article
2013A family of secreted pathogenesis-related proteins in Candida albicans
Röhm, M.; Lindemann, E.; Hiller, E.; Ermert, D.; Lemuth, K.; Trkulja, D.; Sogukpinar, O.; Brunner, H.; Rupp, S.; Urban, C.F.; Sohn, K.
Journal Article
2013Metatranscriptome analysis reveals new insights in probiotic/host/Candida interaction in oral Candidiasis
Mailander-Sanchez, D.; Wagener, J.; Braunsdorf, C.; Grumaz, C.; Lorenz, S.; Sohn, K.; Schaller, M.
Conference Paper, Journal Article
2013Species and condition specific adaptation of the transcriptional landscapes in Candida albicans and Candida dubliniensis
Grumaz, C.; Lorenz, S.; Stevens, P.; Lindemann, E.; Schock, U.; Retey, J.; Rupp, S.; Sohn, K.
Journal Article
2012Differential metatranscriptomic profiling during Candida infections
Grumaz, C.; Hoffmann, H.; Lorenz, S.; Lindemann, E.; Stevens, P.; Rupp, S.; Sohn, K.
Conference Paper, Journal Article
2012An expanded genetic code in Candida albicans to study molecular interactions in vivo
Palzer, S.; Bantel, Y.; Kazenwadel, F.; Berg, M.; Rupp, S.; Sohn, K.
Conference Paper, Journal Article
2012Highly-integrated lab-on-chip system for point-of-care multiparameter analysis
Schumacher, Soeren; Nestler, Jörg; Otto, Thomas; Wegener, Michael; Ehrentreich-Förster, Eva; Michel, Dirk; Wunderlich, Kai; Palzer, Silke; Sohn, Kai; Weber, Achim; Burgard, Matthias; Grzesiak, Andrzej; Teichert, Andreas; Brandenburg, Albrecht; Koger, Birgit; Albers, Jörg; Nebling, Eric; Bier, Frank F.
Journal Article
2011Adaptation, adhesion and invasion during interaction of Candida albicans with the host. Focus on the function of cell wall proteins
Hiller, E.; Zavrel, M.; Hauser, N.; Sohn, K.; Burger-Kentischer, A.; Lemuth, K.; Rupp, S.
Journal Article
2010A multidimensional electrophoretic system of separation for the analysis of gene expression (MESSAGE)
Lindemann, E.; Rohde, B.; Rupp, S.; Regenbogen, J.; Sohn, K.
Journal Article
2009Characterization of genes encoding for cell surface proteins induced during hostpathogen interaction
Zavrel, M.; Hernandez, R.; Sohn, K.; Hauser, N.; Rupp, S.
Abstract
2009Host-pathogen interactions
: Rupp, S. (Hrsg.); Sohn, K. (Hrsg.)
Book
2009Human epithelial model systems for the study of Candida infections in vitro. Pt.I: Adhesion to epithelial models
Sohn, K.; Rupp, S.
Book Article
2008Organotypical tissue cultures from adult murine colon as an in vitro model of intestinal mucosa
Bareiss, P.M.; Metzger, M.; Sohn, K.; Rupp, S.; Frick, J.S.; Autenrieth, I.B.; Lang, F.; Schwarz, H.; Skutella, T.; Just, L.
Journal Article
2007A novel conserved nuclear localization signal is recognized by a group of yeast importins
Fries, T.; Betz, C.; Sohn, K.; Caesar, S.; Schlenstedt, G.; Bailer, S.M.
Journal Article
2006Controlled cell attachment, using plasma deposited polymer microstructures: A novel study of cells-substrate interactions
Sciarratta, V.; Sohn, K.; Burger-Kentischer, A.; Brunner, H.; Oehr, C.
Book Article
2006Getting in touch with Candida albicans: The cell wall of a fungal pathogen
Sohn, K.; Schwenk, J.; Urban, C.; Lechner, J.; Schweikert, M.; Rupp, S.
Journal Article
2006An in vitro assay to study the transcriptional response during adherence of Candida albicans to different human epithelia
Sohn, K.; Senyürek, I.; Fertey, J.; Königsdorfer, A.; Joffroy, C.; Hauser, N.; Zelt, G.; Brunner, H.; Rupp, S.
Journal Article
2006Universelles Verfahren für die Genexpressionsanalyse
Lindemann, E.; Rupp, S.; Sohn, K.
Journal Article
2006Verbessertes elektrophoretisches Trennverfahren fuer die Analyse der Genexpression
Sohn, K.; Rupp, S.
Patent
2005Identification and Characterization of Cor33p, a novel protein implicated in tolerance towards oxidative stress in Candida albicans
Sohn, K.; Röhm, M.; Urban, C.; Saunders, N.; Rothenstein, D.; Lottspeich, F.; Schröppel, K.; Rupp, S.
Journal Article
2005Identification of covalently-linked proteins in the cell wall of C. albicans
Hiller, E.; Sohn, K.; Urban, C.; Gnau, V.; Nordheim, A.; Brunner, H.; Rupp, S.
Abstract
2005The moonlighting protein Tsa1p is implicated in oxidative stress response and in cell wall biogenesis in Candida albicans
Urban, C.; Sohn, K.; Schröppel, K.; Brunner, H.; Rupp, S.
Journal Article
2005Thioredoxin-Peroxidase von C. albicans als virulenzspezifischer Marker
Urban, C.; Sohn, K.; Brunner, H.; Rupp, S.
Patent
2005The transcriptional response in C. albicans during adhesion to mammalian epithelia
Sohn, K.; Senyürek, I.; Hauser, N.; Zelt, G.; Brunner, H.; Rupp, S.
Abstract
2004RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1
Lotz, H.; Sohn, K.; Brunner, H.; Mühlschlegel, F.A.; Rupp, S.
Journal Article
2003Biochips mit Dimorphismus-spezifischen Faktoren aus Candida albicans
Sohn, K.; Rupp, S.; Brunner, H.
Patent
2003EFG1 is a major regulator of cell wall dynamics in Candida albicans as revealed by DNA microarrays
Sohn, K.; Urban, C.; Brunner, H.; Rupp, S.
Journal Article
2003Identification of cell surface determinants in Candida albicans
Urban, C.; Sohn, K.; Lottspeich, F.; Schweikert, M.; Brunner, H.; Rupp, S.
Journal Article
2003Identification of cell surface determinants in Candida albicans reveals Tsa1p, a protein differentially localized in the cell
Urban, C.; Sohn, K.; Lottspeich, F.; Brunner, H.; Rupp, S.
Journal Article
2001Hyphenspezifische Faktoren aus Candida albicans
Rupp, S.; Johannes, F.; Sohn, K.
Patent
2001Regulation of cell wall dynamics in Candida albicans by CPH1 and EFG1, two transcription factors essential for virulence
Sohn, K.; Urban, C.; Brunner, H.; Rupp, S.
Conference Paper, Journal Article
2000Localization and topology of ratp28, a member of a novel family of putative steroid-binding proteins
Nölte, I.; Jeckel, D.; Wieland, F.T.; Sohn, K.
Journal Article
2000A microarray enzyme-linked immunosorbent assay for autoimmune diagnostics
Joos, T.O.; Schrenk, M.; Hopfl, P.; Kroger, K.; Chowdhury, U.; Stoll, D.; Schnorer, D.; Durr, M.; Herick, K.; Rupp, S.; Sohn, K.; Hammerle, H.
Journal Article