Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Design, Synthesis, and Structure - Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase
Hiesinger, K.; Kramer, J.S.; Beyer, S.; Eckes, T.; Brunst, S.; Flauaus, C.; Wittmann, S.K.; Weizel, L.; Kaiser, A.; Kretschmer, S.B.M.; George, S.; Angioni, C.; Heering, J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Schmidtko, A.; Pogoryelov, D.; Pfeilschifter, J.; Hofmann, B.; Steinhilber, D.; Schwalm, S.; Proschak, E.
Journal Article
2020Neuropathic and cAMP-induced pain behavior is ameliorated in mice lacking CNGB1
Kallenborn-Gerhardt, W.; Metzner, K.; Lu, R.; Petersen, J.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Nemirovski, D.; Del Turco, D.; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Journal Article
2020Rab27a Contributes to the Processing of Inflammatory Pain in Mice
Gross, T.; Wack, G.; Syhr, K.M.J.; Tolmachova, T.; Seabra, M.C.; Geisslinger, G.; Niederberger, E.; Schmidtko, A.; Kallenborn-Gerhardt, W.
Journal Article
2019Loxapine for treatment of patients with refractory, chemotherapy-induced neuropathic pain: A prematurely terminated pilot study showing efficacy but limited tolerability
Schmiedl, S.; Peters, D.; Schmalz, O.; Mielke, A.; Rossmanith, T.; Diop, S.; Piefke, M.; Thürmann, P.; Schmidtko, A.
Journal Article
2019Reduced neuropathic pain behavior in mice lacking the cyclic nucleotide-gated channel subunit CNGB1
Kallenborn-Gerhardt, W.; Lu, R.; Petersen, J.J.; Metzner, K.; Kuth, M.S.; Heine, S.; Drees, O.; Paul, M.; Becirovic, E.; Kennel, L.; Flauaus, C.; Gross, T.; Wack, G.; Hohmann, S.W.; Turco, D. del; Biel, M.; Geisslinger, G.; Michalakis, S.; Schmidtko, A.
Journal Article
2018Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology
Schierle, S.; Flauaus, C.; Heitel, P.; Willems, S.; Schmidt, J.; Kaiser, A.; Weizel, L.; Goebel, T.; Kahnt, A.S.; Geisslinger, G.; Steinhilber, D.; Wurglics, M.; Rovati, G.E.; Schmidtko, A.; Proschak, E.; Merk, D.
Journal Article
2017Cleavage of SNAP‐25 ameliorates cancer pain in a mouse model of melanoma
Olbrich, K.; Costard, L.; Möser, C.V.; Syhr, K.M.J.; King‐Himmelreich, T.S.; Wolters, M.C.; Schmidtko, A.; Geisslinger, G.; Niederberger, E.
Journal Article
2017Rab7 - A novel redox target that modulates inflammatory pain processing
Kallenborn-Gerhardt, W.; Möser, C.V.; Lorenz, J.E.; Steger, M.; Heidler, J.; Scheving, R.; Petersen, J.; Kennel, L.; Flauaus, C.; Lu, R.; Edinger, A.L.; Tegeder, I.; Geisslinger, G.; Heide, H.; Wittig, I.; Schmidtko, A.
Journal Article
2016The H2S-producing enzyme CSE is dispensable for chronic pain signaling
Syhr, K.M.J.; Boosen, M.; Hohmann, S.W.; Longen, S.; Köhler, Y.; Pfeilschifter, J.; Beck, K.F.; Geisslinger, G.; Schmidtko, A.; Kallenborn-Gerhardt, W.
Journal Article
2015The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain
Syhr, K.M.J.; Boosen, M.; Hohmann, S.W.; Longen, S.; Köhler, Y.; Pfeilschifter, J.; Beck, K.-F.; Geisslinger, G.; Schmidtko, A.; Kallenborn-Gerhardt, W.
Journal Article
2015Slack Channels Expressed in Sensory Neurons Control Neuropathic Pain in Mice
Lu, R.; Bausch, A.E.; Kallenborn-Gerhardt, W.; Stoetzer, C.; Debruin, N.; Ruth, P.; Geisslinger, G.; Leffler, A.; Lukowski, R.; Schmidtko, A.
Journal Article
2014BKCa channels expressed in sensory neurons modulate inflammatory pain in mice
Lu, R.; Lukowski, R.; Sausbier, M.; Zhang, D.D.; Sisignano, M.; Schuh, C.D.; Kuner, R.; Ruth, P.; Geisslinger, G.; Schmidtko, A.
Journal Article
2014Lack of effect of a P2Y6 receptor antagonist on neuropathic pain behavior in mice
Syhr, K.M.J.; Kallenborn-Gerhardt, W.; Lu, R.R.; Olbrich, K.; Schmitz, K.; Männich, J.; Ferreiros-Bouzas, N.; Geisslinger, G.; Niederberger, E.; Schmidtko, A.
Journal Article
2014Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity
Kallenborn-Gerhardt, W.; Hohmann, S.W.; Syhr, K.M.J.; Schröder, K.; Sisignano, M.; Weigert, A.; Lorenz, J.E.; Lu, R.R.; Brüne, B.; Brandes, R.P.; Geisslinger, G.; Schmidtko, A.
Journal Article
2014Oxidant-induced activation of cGMP-dependent protein kinase Iα contributes to neuropathic pain processing after nerve injury
Kallenborn-Gerhardt, W.; Lorenz, J.E.; Lu, R.; Eaton, P.; Geisslinger, G.; Schmidtko, A.
Journal Article
2014Oxidant-Induced Activation of cGMP-Dependent Protein Kinase Iα Mediates Neuropathic Pain After Peripheral Nerve Injury
Lorenz, J.E.; Kallenborn-Gerhard, W.; Lu, R.; Syhr, K.M.J.; Eaton, P.; Geisslinger, G.; Schmidtko, A.
Journal Article
2014Phosphodiesterase 2A Localized in the Spinal Cord Contributes to Inflammatory Pain Processing
Kallenborn-Gerhard, W.; Lu, R.; Bothe, A.; Thomas, D.; Schlaudraff, J.; Lorenz, J.E.; Lippold, N.; Real, C.I.; Ferreirós, N.; Geisslinger, G.; Turco, D. Del; Schmidtko, A.
Journal Article
2013NOXious signaling in pain processing
Kallenborn-Gerhardt, W.; Schröder, K.; Geisslinger, G.; Schmidtko, A.
Journal Article