Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Forced degradation studies to identify critical process parameters for the purification of infectious measles virus
Loewe, D.; Häussler, J.; Grein, T.A.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2018Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells
Zitzmann, J.; Weidner, T.; Eichner, G.; Salzig, D.; Czermak, P.
Journal Article
2018High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system
Grein, T.A.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Journal Article
2018Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression
Zitzmann, J.; Schreiber, C.; Eichmann, J.; Bilz, R.O.; Salzig, D.; Weidner, T.; Czermak, P.
Journal Article
2017Baculovirus-induced recombinant protein expression in human mesenchymal stromal stem cells: A promoter study
Sprick, G.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2017Comparison of cell-based versus cell-free mammalian systems for the production of a recombinant human bone morphogenic growth factor
Jérôme, V.; Thoring, L.; Salzig, D.; Kubick, S.; Freitag, R.
Journal Article
2017A high-throughput expression screening platform to optimize the production of antimicrobial peptides
Schreiber, C.; Müller, H.; Birrenbach, O.; Klein, M.; Heerd, D.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2017Microcarrier choice and bead-to-bead transfer for human mesenchymal stem cells in serum-containing and chemically defined media
Leber, J.; Barekzai, J.; Blumenstock, M.; Pospisil, B.; Salzig, D.; Czermak, P.
Journal Article
2017Non-invasive raman spectroscopy and quantitative real-time PCR distinguish among undifferentiated human mesenchymal stem cells and redifferentiated nucleus pulposus cells and chondrocytes In Vitro
Ehlicke, F.; Köster, N.; Salzig, D.; Czermak, P.
Journal Article
2017Reassessment of inclusion body-based production as a versatile opportunity for difficult-to-express recombinant proteins
Hoffmann, D.; Ebrahimi, M.; Gerlach, D.; Salzig, D.; Czermak, P.
Journal Article
2017Reprint of "Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion"
Grein, T.A.; Leber, J.; Blumenstock, M.; Petry, F.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2017Screening different host cell lines for the dynamic production of measles virus
Grein, T.A.; Schwebel, F.; Kress, M.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Journal Article
2016Attachment, growth, and detachment of human mesenchymal stem cells in a chemically defined medium
Salzig, D.; Leber, J.; Merkewitz, K.; Lange, M.C.; Köster, N.; Czermak, P.
Journal Article
2016Investigation of Factors Influencing Recombinant Human BMP2 Expression in Mammalian cells
Jérôme, V.; Thoring, L.; Salzig, D.; Kubick, S.; Freitag, R.
Journal Article
2016Manufacturing of human umbilical cord mesenchymal stromal cells on microcarriers in a dynamic system for clinical use
Petry, F.; Smith, J.R.; Leber, J.; Salzig, D.; Czermak, P.; Weiss, M.L.
Journal Article
2016Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion
Grein, T.A.; Leber, J.; Blumenstock, M.; Petry, F.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2016The potential of the Galleria mellonella innate immune system is maximized by the co-presentation of diverse antimicrobial peptides
Bolouri Moghaddam, M.R.; Tonk, M.; Schreiber, C.; Salzig, D.; Czermak, P.; Vilcinskas, A.; Rahnamaeian, M.
Journal Article
2016Single-Step RNA Extraction from Different Hydrogel-Embedded Mesenchymal Stem Cells for Quantitative Reverse Transcription-Polymerase Chain Reaction Analysis
Köster, N.; Schmiermund, A.; Grubelnig, S.; Leber, J.; Ehlicke, F.; Czermak, P.; Salzig, D.
Journal Article
2015Considerations for the process development of insect-derived antimicrobial peptide production
Müller, H.; Salzig, D.; Czermak, P.
Journal Article
2015Development of an insect metalloproteinase inhibitor drug carrier system for application in chronic wound infections
Eisenhardt, M.; Dobler, D.; Schlupp, P.; Schmidts, T.; Salzig, M.; Vilcinskas, A.; Salzig, D.; Czermak, P.; Keusgen, M.; Runkel, F.
Journal Article
2015Micro-bubble aeration in turbulent stirred bioreactors: Coalescence behavior in Pluronic F68 containing cell culture media
Druzinec, D.; Salzig, D.; Kraume, M.; Czermak, P.
Journal Article
2015Oncolytic measles viruses produced at different scales under serum-free conditions
Weiss, K.; Gerstenberger, J.; Salzig, D.; Mühlebach, M.D.; Cichutek, K.; Pörtner, R.; Czermak, P.
Journal Article
2015A rapid method for an offline glycerol determination during microbial fermentation
Kuhn, J.; Müller, H.; Salzig, D.; Czermak, P.
Journal Article
2014Bioreactor Expansion of Human Mesenchymal Stem Cells According to GMP Requirements
Elseberg, C.L.; Salzig, D.; Czermak, P.
Book Article
2014hMSC production in disposable bioreactors in compliance with cGMP guidelines and PAT
Oppermann, T.; Leber, J.; Elseberg, C.; Salzig, D.; Czermak, P.
Journal Article
2013Optimization of insect cell based protein production processes - online monitoring, expression systems, scale up
Druzinec, D.; Salzig, D.; Brix, A.; Kraume, M.; Vilcinskas, A.; Kollewe, C.; Czermak, P.
Book Article