Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2020Amyloid-beta peptides trigger aggregation of alpha-synuclein in vitro
Köppen, Janett; Schulze, Anja; Machner, Lisa; Wermann, Michael; Eichentopf, Rico; Guthardt, Max; Hähnel, Angelika; Klehm, Jessica; Kriegeskorte, Marie-Christin; Hartlage-Rübsamen, Maike; Morawski, Markus; Hörsten, Stephan von; Demuth, Hans-Ulrich; Roßner, Steffen; Schilling, Stephan
Journal Article
2019Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer's disease
Hartlage-Rübsamen, Maike; Ratz, Veronika; Zeitschel, Ulrike; Finzel, Lukas; Machner, Lisa; Köppen, Janett; Schulze, Anja; Demuth, Hans-Ulrich; Hörsten, Stephan von; Höfling, Corinna; Roßner, Steffen
Journal Article
2019QUINT: Workflow for quantification and spatial analysis of features in histological images from rodent brain
Yates, Sharon C.; Groeneboom, Nicolaas E.; Coello, Christopher; Lichtenthaler, Stefan F.; Kuhn, Peer-Hendrik; Demuth, Hans-Ulrich; Hartlage-Rübsamen, Maike; Roßner, Steffen; Leergaard, Trygve; Kreshuk, Anna; Puchades, Maja A.; Bjaalie, Jan G.
Journal Article
2018Dipeptidyl-peptidase activity of meprin β links N-truncation of Aβ with glutaminyl cyclase-catalyzed pGlu-Aβ formation
Schlenzig, Dagmar; Cynis, Holger; Hartlage-Rübsamen, Maike; Zeitschel, Ulrike; Menge, Katja; Fothe, Anja; Ramsbeck, Daniel; Spahn, Claudia; Wermann, Michael; Roßner, Steffen; Buchholz, Mirko; Schilling, Stephan; Demuth, Hans-Ulrich
Journal Article
2018Immunohistochemical evidence from APP-transgenic mice for glutaminyl cyclase as drug target to diminish pE-abeta formation
Hartlage-Rübsamen, Maike; Bluhm, Alexandra; Piechotta, Anke; Linnert, Miriam; Rahfeld, Jens-Ulrich; Demuth, Hans-Ulrich; Lues, Inge; Kuhn, Peer-Hendrik; Lichtenthaler, Stefan F.; Roßner, Steffen; Höfling, Corinna
Journal Article
2015Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes
Waniek, Alexander; Hartlage-Rübsamen, Maike; Höfling, Corinna; Kehlen, Astrid; Schilling, Stephan; Demuth, Hans-Ulrich; Roßner, Steffen
Journal Article
2015Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease
Hartlage-Rübsamen, Maike; Waniek, Alexander; Meißner, Juliane; Morawski, Markus; Schilling, Stephan; Jäger, Carsten; Kleinschmidt, Martin; Cynis, Holger; Kehlen, Astrid; Arendt, Thomas; Demuth, Hans-Ulrich; Roßner, Steffen
Journal Article
2014Glutaminyl cyclase in human cortex: Correlation with (pGlu)-amyloid-β load and cognitive decline in Alzheimer's disease
Morawski, Markus; Schilling, Stephan; Kreuzberger, Moritz; Waniek, Alexander; Jäger, Carsten; Koch, Birgit; Cynis, Holger; Kehlen, Astrid; Arendt, Thomas; Hartlage-Rübsamen, Maike; Demuth, Hans-Ulrich; Roßner, Steffen
Journal Article
2014Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC
Höfling, Corinna; Indrischek, Henrike; Höpcke, Theodor; Waniek, Alexander; Cynis, Holger; Koch, Birgit; Schilling, Stephan; Morawski, Markus; Demuth, Hans-Ulrich; Roßner, Steffen; Hartlage-Rübsamen, Maike
Journal Article
2014A non-canonical function of eukaryotic elongation factor 1A1: Regulation of interleukin-6 expression
Schulz, Ingo; Engel, Claudia; Niestroj, André J.; Kehlen, Astrid; Rahfeld, Jens-Ulrich; Kleinschmidt, Martin; Lehmann, Karola; Roßner, Steffen; Demuth, Hans-Ulrich
Journal Article