Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2013Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices
Switalla, Simone; Knebel, Jan; Ritter, Detlef; Dasenbrock, Clemens; Krug, Norbert; Braun, Armin; Sewald, Katherina
Journal Article
2012Acute cigarette smoke exposure induces cytotoxicity and inflammation in living tissue of precision-cut lung slices
Lauenstein, Lan; Switalla, Simone; Ritter, Detlef; Knebel, Jan; Dasenbrock, Clemens; Braun, Armin; Sewald, Katherina
Abstract, Conference Paper
2012Ultra wideband cascade low noise amplifier implemented in 100-nm GaAs metamorphic-HEMTS technology
Dyskin, A.; Ritter, D.; Kallfass, I.
Conference Paper
2011A 10-GS/s multibit delta-sigma analog-to-digital converter in an InP HBT technology
Kraus, S.; Kallfass, I.; Makon, R.E.; Driad, R.; Moyal, M.; Ritter, D.
Conference Paper
2011A 20-GHz bipolar latched comparator with improved sensitivity implemented in InP HBT technology
Kraus, S.; Kallfass, I.; Makon, R.E.; Driad, R.; Moyal, M.; Ritter, D.
Journal Article
2011Discrepancy between high clastogenic activity of trans-beta-nitrostyrene in vitro and lack in carcinogenicity might be related to inactivating metabolism and its high reactivity towards thiol groups
Ziemann, Christina; Apitius, Florian; Elend, Manfred; Baumgartner, S.; Volk, J.; Ritter, Detlef; Steinfelder, H.J.; Schuchardt, Sven
Conference Paper, Journal Article
2011High-speed selector-driver using abrupt delta-doped InP/InGaAs/InP DHBTs
Driad, R.; Makon, R.E.; Ritter, D.
Journal Article
2011Improvement of experimental methods for toxicological characterization of inhalable substances in vitro by in situ analysis of the cellular status based on fluorescence stainings
Ritter, Detlef; Knebel, Jan
Conference Paper, Journal Article
2011Prävalidierungsstudie zur Prüfung der toxischen Wirkung von inhalativ wirksamen Stoffen (Gase)
Knebel, Jan; Ritter, Detlef; Berger-Preiß, Edith; Kock, Heiko; Liebsch, Manfred; Smirnova, Lena; Pirow, Ralph; Linsel, Gunter; Bauer, Mario; Graebsch, Carolin
Study
2011Toxicological characterization of inhalable substances and aerosols in vitro: Enhancement of experimental methods by in situ fluorescence analysis of the cellular status during exposure
Ritter, Detlef; Knebel, Jan
Journal Article, Conference Paper
2011Untersuchungen zum biologischen Effekt inhalierbarer Aerosole in vitro
Lange, Carsten
: Scharfenberg, Klaus (Erstprüfer); Dasenbrock, Clemens (Zweitprüfer); Knebel, Jan (Betreuer); Ritter, Detlef (Betreuer)
Bachelor Thesis
2010Comparative mechanistical investigations on the genotoxic potential of nitrovinyluracil derivatives
Heinemann, D.; Ritter, D.; Kasper, C.; Eger, K.; Steinfelder, H.J.; Ziemann, C.
Abstract, Journal Article
2010Effects of acute in vitro exposure of murine precision-cut lung slices to gaseous nitrogen dioxide and ozone in an air-liquid interface (ALI) culture
Switalla, S.; Knebel, J.; Ritter, D.; Krug, N.; Braun, A.; Sewald, K.
Journal Article
2010High linearity 2-bit current steering InP/GaInAs DHBT digital-to-analog converter
Kraus, S.; Kallfass, I.; Makon, R.E.; Rosenzweig, J.; Driad, R.; Moyal, M.; Ritter, D.
Conference Paper
2010PCLS (Precision Cut Lung Slices) as a putative model for genotoxicity testing by application of the comet assay
Ritter, D.; Switalla, S.; Sewald, K.; Knebel, J.
Abstract, Conference Paper
2010Sensitivity of a 20-GS/s InP DHBT latched comparator
Kraus, S.; Makon, R.E.; Kallfass, I.; Driad, R.; Moyal, M.; Ritter, D.
Conference Paper
2010Testing of the toxicity of volatile compounds on human lung cells using the Air/Liquid Interface (ALI) culturing and exposure technique: A prevalidation study
Pirow, R.; Smirnova, L.; Liebsch, M.; Tharmann, J.; Luch, A.; Graebsch, C.; Bauer, M.; Linsel, G.; Siemers, R.; Otto, C.; Berger-Preiß, E.; Kock, H.; Oertel, A.; Ritter, D.; Knebel, J.
Journal Article, Conference Paper
2009Anordnung zur Durchfuehrung eines Verfahrens zur Untersuchung der Wirkung eines gasfoermigen Mediums auf ein biologisches Pruefsystem unter Verwendung eines extrazellulaeren Metabolisierungssystems
Knebel, J.; Ritter, D.
Patent
2009Cytokine production after acute exposure of precision cut lung slices to NO2 and O3
Switalla, S.; Ritter, D.; Krug, N.; Knebel, J.; Braun, A.; Sewald, K.
Abstract, Journal Article
2009Geltraeger zur Durchfuehrung des COMET-Assays mit Automatisierungsmoeglichkeit im Roboter-gestuetzten Analysebetrieb zur Realisierung eines Hochdurchsatz-Verfahrens
Ritter, D.; Knebel, J.
Patent
2009Genotoxicity testing in vitro - development of a higher throughput analysis method based on the comet assay
Ritter, D.; Knebel, J.
Journal Article, Conference Paper
2008Precision cut lung slices for testing of gaseous compounds
Switalla, S.; Sewald, K.; Ritter, D.; Henjakovic, M.; Krug, N.; Knebel, J.; Braun, A.
Conference Paper, Journal Article
2008Referenzpraeparat fuer eine Untersuchungsmethode unter Verwendung eines bildgebenden Erfassungs- und Auswertungsverfahrens
Ritter, D.; Knebel, J.
Patent
2008Standardization of the COMET-assay
Ritter, D.; Knebel, J.
Conference Paper, Journal Article
2007Development of a procedure for high content and higher throughput analysis of DNA-damage based on the COMET-assay
Ritter, D.; Knebel, J.; Krueger, D.
Conference Paper, Journal Article
2007Geltraeger zur Durchfuehrung des COMET-Assays mit Automatisierungsmoeglichkeit im Roboter-gestuetzten Analysebetrieb zur Realisierung eines Hochdurchsatz-Verfahrens
Ritter, D.; Knebel, J.
Patent
2007Verfahren zur Untersuchung der Wirkung eines gasfoermigen Mediums auf ein biologisches Pruefsystem unter Verwendung eines extrazellulaeren Metabolisierungssystems sowie Vorrichtung zur Durchfuehrung des Verfahrens
Knebel, J.; Ritter, D.
Patent
2004Comparative assessment of toxicities of mainstream smoke from commercial cigarettes
Ritter, D.; Knebel, J.W.; Aufderheide, M.
Journal Article
2003Exposure of human lung cells to inhalable substances
Ritter, D.; Knebel, J.W.; Aufderheide, M.
Journal Article
2003An improved in vitro model for testing the pulmonary toxicity of complex mixtures such as cigarette smoke
Aufderheide, M.; Knebel, J.W.; Ritter, D.
Journal Article
2003Novel approaches for studying pulmonary toxicity in vitro
Aufderheide, M.; Knebel, J.W.; Ritter, D.
Journal Article
2002Direct exposure of human lung cells to native cigarette mainstream smoke
Ritter, D.; Knebel, J.; Aufderheide, M.
Conference Paper
2002Exposure of human lung cells to native diesel motor exhaust - development of an optimized in vitro test strategy
Knebel, J.W.; Ritter, D.; Aufderheide, M.
Journal Article
2002A method for the in vitro exposure of human cells to environmental and complex gaseous mixtures
Aufderheide, M.; Knebel, J.W.; Ritter, D.
Journal Article
2002A new system for the direct in vitro exposure of human lung cells to native cigarette mainstream smoke
Ritter, D.; Knebel, J.W.; Aufderheide, M.
Conference Paper
2001Development and validation of a semiautomatic system for generation and deposition of sprays on isolated cells of the respiratory tract
Knebel, J.W.; Ritter, D.; Hoffmann, K.; Lödding, H.; Windt, H.; Koch, W.; Aufderheide, M.
Journal Article
2001In vitro exposure of isolated cells to native gaseous compounds - development and validation of an optimized system for human lung cells
Ritter, D.; Knebel, J.W.; Aufderheide, M.
Journal Article
2001A method for in vitro analysis of the biological activity of complex mixtures such as sidestream cigarette smoke
Aufderheide, M.; Ritter, D.; Knebel, J.W.; Scherer, G.
Journal Article
2000Entwicklung eines Systems zur Untersuchung der biologischen Aktivität atmospherischer Gase in vitro
Ritter, D.
: Alves, J. (Prüfer); Aufderheide, M. (Prüfer)
Dissertation
1999Development of a cell culture model system for routine testing of substances inducing oxidative stress
Ritter, D.; Knebel, J.W.; Aufderheide, M.; Mohr, U.
Journal Article
1998Development of an in vitro system for studying effects of native and photochemically transformed gaseous compounds using an air/liquid culture technique
Knebel, J.W.; Ritter, D.; Aufderheide, M.
Journal Article
1997Development of a cell culture system for studying effects of native and photochemically transformed gaseous compounds using an air/liquid culture technique
Ritter, D.; Knebel, J.W.; Aufderheide, M.; Palm, W.-U.; Zetzsch, C.
Conference Paper