Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: A feasibility randomized clinical trial
Greulich, Timm; Hohlfeld, Jens M.; Neuser, Petra; Lueer, Katrin; Klemmer, Andreas; Schade-Brittinger, Carmen; Harnisch, Susanne; Garn, Holger; Renz, Harald; Homburg, Ursula; Renz, Jonas; Kirsten, Anne; Pedersen, Frauke; Müller, Meike; Vogelmeier, Claus F.; Watz, Henrik
Journal Article
2017Blood eosinophils predict therapeutic effects of a GATA3-specific DNAzyme in asthma patients
Krug, N.; Hohlfeld, J.M.; Buhl, R.; Renz, J.; Garn, H.; Renz, H.
Journal Article
2015Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
Krug, Norbert; Hohlfeld, Jens Michael; Kirsten, Anne-Marie; Kornmann, Oliver; Beeh, Kai-Michael; Kappeler, Dominik; Korn, Stephanie; Ignatenko, Stanislav; Timmer, Wolfgang; Rogon, Cordelia; Zeitvogel, Jana; Zhang, Nan; Bille, Joachim; Homburg, Ursula; Turowska, Agnieszka; Bachert, Claus; Werfel, Thomas; Buhl, Roland; Renz, Jonas; Garn, Holger; Renz, Harald
Journal Article
2015Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma
Homburg, Ursula; Renz, Harald; Timmer, Wolfgang; Hohlfeld, Jens M.; Seitz, Friedeborg; Lüer, Katrin; Mayer, Alexandra; Wacker, Anja; Schmidt, Oliver; Kuhlmann, Jens; Turowska, Agnieszka; Roller, Julia; Kutz, Klaus; Schlüter, Gerhard; Krug, Norbert; Garn, Holger
Journal Article
2013Safety profile and pharmacokinetics of an inhaled GATA-3-specific DNAzyme in a phase Ib study in patients with stable allergic asthma
Hohlfeld, Jens; Lüer, Katrin; Krug, Norbert; Turowska, Agnieszka; Renz, Harald; Garn, Holger; Homburg, Ursula
Journal Article, Conference Paper
2006The course of allergen-induced leukocyte infiltration in human and experimental asthma
Lommatzsch, M.; Julius, P.; Kuepper, M.; Garn, H.; Bratke, K.; Irmscher, S.; Luttmann, W.; Renz, H.; Braun, A.; Virchow, J.C.
Journal Article
2006Nerve growth factor: The central hub in the development of allergic asthma?
Nassenstein, C.; Schulte-Herbrüggen, O.; Renz, H.; Braun, A.
Journal Article
2005Blocking IL-15 prevents the induction of allergen-specific T cells and allergic inflammation in vivo
Ruckert, R.; Brandt, K.; Braun, A.; Hoymann, H.G.; Herz, U.; Budagian, V.; Durkop, H.; Renz, H.; Bulfone-Paus, S.
Journal Article
2005IL-15 antagonists inhibit allergic responses and airway hyperresponsiveness in a murine model of asthma bronchiale
Bulfone-Paus, S.; Brandt, K.; Braun, A.; Hoymann, H.G.; Herz, U.; Renz, H.; Ruckert, R.
Abstract
2005The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
Doganci, A.; Eigenbrod, T.; Krug, N.; Sanctis, G.T. de; Hausding, M.; Erpenbeck, V.J.; Haddad, E.-B.; Schmitt, E.; Bopp, T.; Kallen, K.-J.; Herz, U.; Schmitt, S.; Luft, C.; Hecht, O.; Hohlfeld, J.M.; Ito, H.; Nishimoto, N.; Yoshizaki, K.; Kishimoto, T.; Rose-John, S.; Renz, H.; Neurath, M.F.; Galle, P.R.; Finotto, S.
Journal Article
2005The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
Doganci, A.; Eigenbrod, T.; Krug, N.; Sanctis, G.T. de; Hausding, M.; Erpenbeck, V.J.; Haddad, E.-B.; Lehr, H.A.; Schmitt, E.; Bopp, T.; Kallen, K.-J.; Herz, U.; Schmitt, S.; Luft, C.; Hecht, O.; Hohlfeld, J.M.; Ito, H.; Nishimoto, N.; Yoshizaki, K.; Kishimoto, T.; Rose-John, S.; Renz, H.; Neurath, M.F.; Galle, P.R.; Finotto, S.
Journal Article
2005Neurotrophin effects on eosinophils in allergic inflammation
Nassenstein, C.; Braun, A.; Nockher, W.A.; Renz, H.
Journal Article
2005Neurotrophins in murine viscera: A dynamic pattern from birth to adulthood
Lommatzsch, M.; Quarcoo, D.; Schulte-Herbrüggen, O.; Weber, H.; Virchow, J.C.; Renz, H.; Braun, A.
Journal Article
2005A role for brain-derived neurotrophic factor in B cell development
Schuhmann, B.; Dietrich, A.; Sel, S.; Hahn, C.; Klingenspor, M.; Lommatzsch, M.; Gudermann, T.; Braun, A.; Renz, H.; Nockher, W.A.
Journal Article
2005Tumor necrosis factor-alpha and interleukin-6 regulate secretion of brain-derived neurotrophic factor in human monocytes
Schulte-Herbrüggen, O.; Nassenstein, C.; Lommatzsch, M.; Quarcoo, D.; Renz, H.; Braun, A.
Journal Article
2004Brain-derived neurotrophic factor (BDNF) contributes to neuronal dysfunction in a model of allergic airway inflammation
Braun, A.; Lommatzsch, M.; Neuhaus-Steinmetz, U.; Quarcoo, D.; Glaab, T.; MacGregor, G.P.; Fischer, A.; Renz, H.
Journal Article
2004Nerve growth factor induces increased airway inflammation via a neuropeptide-dependent mechanism in a transgenic animal model of allergic airway inflammation
Quarcoo, D.; Schulte-Herbrüggen, O.; Lommatzsch, M.; Schierhorn, K.; Hoyle, G.W.; Renz, H.; Braun, A.
Journal Article
2004Neuroimmune dysbalance in bronchial asthma
Kerzel, S.; Päth, G.; Nockher, W.A.; Quarcoo, D.; Raap, U.; Gronenberg, D.A.; Thai Dinh, Q.; Fischer, A.; Braun, A.; Renz, H.
Conference Paper
2003Neuroimmune control of the pulmonary immune response
Braun, A.; Renz, H.
Book Article
2003Neuroimmune interactions in the pathogenesis of allergic asthma
Braun, A.; Nockher, W.A.; Renz, H.
Book Article
2003Neurotrophins in allergic airway dysfunction what the mouse model is teaching us
Lommatzsch, M.; Braun, A.; Renz, H.
Conference Paper
2003Neurotrophins in allergic airway dysfunction: What the mouse model is teaching us
Lommatzsch, M.; Braun, A.; Renz, H.
Conference Paper, Journal Article
2003The neurotrophins nerve growth factor, brain-derived neurotrophic factor, Neurotrophin-3, and Neurotrophin-4 are survival and activation factors for Eosinophils in patients with allergic bronchial asthma
Nassenstein, C.; Braun, A.; Erpenbeck, V.J.; Lommatzsch, M.; Schmidt, S.; Krug, N.; Luttmann, W.; Renz, H.; Virchow, J.C.
Journal Article
2003Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma
Kerzel, S.; Päth, G.; Nockher, W.A.; Quarcoo, D.; Raap, U.; Groneberg, D.A.; Dinh, Q.T.; Fischer, A.; Braun, A.; Renz, H.
Journal Article
2002Augmentation of allergic early-phase reaction by nerve growth factor
Päth, G.; Braun, A.; Meents, N.; Kerzel, S.; Quarcoo, D.; Raap, U.; Hoyle, G.W.; Nockher, W.A.; Renz, H.
Journal Article
2002Control of nerve growth and plasticity
Braun, A.; Nockher, W.A.; Renz, H.
Journal Article
2002Effects of NGF application on airway inflammation in a Murine model of allergic bronchial asthma
Quarcoo, D.; Päth, G.; Lommatzsch, M.; Renz, H.; Braun, A.
Conference Paper
2001Die mögliche Bedeutung der Neurotrophine in der Pathogenese des allergischen Asthmas
Nassenstein, C.; Mayer, S.; Braun, A.; Lommatzsch, M.; Renz, H.; Luttmann, W.; Virchow, J.C.
Journal Article
2001Nerve growth factor induces airway hyperresponsiveness in mice
Braun, A.; Quarcoo, D.; Schulte-Herbrüggen, O.; Lommatzsch, M.; Hoyle, G.; Renz, H.
Journal Article
2001Die Rolle von Neurotrophinen in der Pathogenese des allergischen Asthma bronchiale
Braun, A.; Renz, H.
Journal Article
2001Stress and atopic eczema
Kupfer, J.; Gieler, U.; Braun, A.; Niemeier, V.; Huzler, C.; Renz, H.
Conference Paper
2001Tidal midexpiratory flow as a measure of airway hyperresponsiveness in allergic mice
Glaab, T.; Daser, A.; Braun, A.; Neuhaus-Steinmetz, U.; Fabel, H.; Alarie, Y.; Renz, H.
Journal Article
1999Abundant production of brain-derived neurotrophic factor by adult visceral epithelia
Lommatzsch, M.; Braun, A.; Mannsfeldt, A.; Botchkarev, V.A.; Botchkareva, N.V.; Paus, R.; Fischer, A.; Lewin, G.R.; Renz, H.
Journal Article
1999Cellular sources of enhanced brain-derived neurotrophic factor production in a mouse model of allergic inflammation notice to professional recruitment and announcement advertisers
Braun, A.; Lommatzsch, M.; Mannsfeld, A.; Neuhaus-Steinmetz, U.; Fischer, A.; Schnoy, N.; Lewin, G.R.; Renz, H.
Journal Article
1999Neurotrophins
Braun, A.; Lommatzsch, M.; Lewin, G.R.; Virchow, J.C.; Renz, H.
Journal Article
1999A new role for neurotrophins
Botchkarev, V.A.; Botchkareva, N.V.; Welker, P.; Metz, M.; Lewin, G.R.; Subramaniam, A.; Bulfone-Paus, S.; Hagen, E.; Braun, A.; Lommatzsch, M.; Renz, H.; Paus, R.
Journal Article
1998BCG infection suppresses allergic sensitization and development of increased airway reactivity in an animal model
Herz, U.; Gerhold, K.; Gruber, C.; Braun, A.; Wahn, U.; Renz, H.; Paul, K.
Journal Article
1998BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin
Botchkarev, V.A.; Botchkareva, N.V.; Lommatzsch, M.; Peters, E.M.; Lewin, G.R.; Subramaniam, A.; Braun, A.; Renz, H.; Paus, R.
Journal Article
1998Neurotrophins are increased in bronchoalveolar lavage fluid after segmental allergen provocation
Virchow, J.C.; Julius, P.; Lommatzsch, M.; Luttmann, W.; Renz, H.; Braun, A.
Journal Article
1986Ein analog-digitales Schnittstellen-IC fuer ISDN
Renz, H.W.; Fiedler, H.-L.; Zimmer, G.
Conference Paper
1985An analog/digital front - end CMOS IC for ISDN
Fiedler, Horst-Lothar; Zimmer, Günter; Renz, H.W.; Wahl, K.
Conference Paper