Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Critical analysis of the commercial potential of plants for the production of recombinant proteins
Schillberg, S.; Raven, N.; Spiegel, H.; Rasche, S.; Buntru, M.
Journal Article
2017Contained molecular farming using plant cell and tissue cultures
Schillberg, S.; Raven, Nicole; Fischer, R.; Twyman, R.M.; Schiermeyer, A.
Book Article
2016High-yield production of a human monoclonal IgG by rhizosecretion in hydroponic tobacco cultures
Madeira, L.M.; Szeto, T.H.; Henquet, M.; Raven, N.; Runions, J.; Huddleston, J.; Garrard, I.; Drake, P.M.W.; Ma, J.K.-C.
Journal Article
2016Plant Cell-Based Recombinant Antibody Manufacturing with a 200 L Orbitally Shaken Disposable Bioreactor
Raven, N.; Schillberg, S.; Rasche, S.
Book Article
2015Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor
Raven, N.; Rasche, S.; Kuehn, C.; Anderlei, T.; Klöckner, W.; Schuster, F.; Henquet, M.; Bosch, D.; Büchs, J.; Fischer, R.; Schillberg, S.
Journal Article
2014Image-based analysis of cell-specific productivity for plant cell suspension cultures
Havenith, H.; Raven, N.; Fiore, S. di; Fischer, R.; Schillberg, S.
Journal Article
2014In situ cell retention of a CHO culture by a reverse-flow diafiltration membrane bioreactor
Meier, K.; Djeljadini, S.; Regestein, L.; Büchs, J.; Carstensen, F.; Wessling, M.; Holland, T.; Raven, N.
Journal Article
2014Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody
Häkkinen, S.T.; Raven, N.; Henquet, M.; Laukkanen, M.-L.; Anderlei, T.; Pitkänen, J.-P.; Twyman, R.M.; Bosch, D.; Oksman-Caldentey, K.-M.; Schillberg, S.; Ritala, A.
Journal Article
2013Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale
Klöckner, W.; Gacem, R.; Anderlei, T.; Raven, N.; Schillberg, S.; Lattermann, C.; Büchs, J.
Journal Article
2013Molecular farming of pharmaceutical proteins using plant suspension cell and tissue cultures
Schillberg, S.; Raven, N.; Fischer, R.; Twyman, R.M.; Schiermeyer, A.
Journal Article
2013Optimization of BY-2 cell suspension culture medium for the production of a human antibody using a combination of fractional factorial designs and the response surface method
Vasilev, N.; Grömping, U.; Lipperts, A.; Raven, N.; Fischer, R.; Schillberg, S.
Journal Article
2012Light-weight optical sensor for standoff detection of fluorescent biosensors
Wehner, M.; Thombansen, U.; Raven, N.; Kühn, C.; Schillberg, S.
Conference Paper
2012Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting
Kirchhoff, Janina; Raven, Nicole; Boes, Alexander; Roberts, Jean L.; Russell, Sean; Treffenfeldt, Wiltrud; Fischer, Rainer; Schinkel, Helga; Schiermeyer, Andreas; Schillberg, Stefan
Journal Article
2011Growth of BY-2 suspension cells and plantibody production in single-use bioreactors
Raven, N.; Schillberg, S.; Kirchhoff, J.; Brändli, J.; Imseng, N.; Eibl, R.
Book Article
2009Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco
Bortesi, L.; Rossato, M.; Schuster, F.; Raven, N.; Stadlmann, J.; Avesani, L.; Falorni, A.; Bazzoni, F.; Bock, R.; Schillberg, S.; Pezzotti, M.
Journal Article
2004Pflanzenzellen als Produktionssystem zur Gewinnung von Interleukin-4-Doppelmutein (IL-4 DM)
Raven, N.
Dissertation
2001Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations
Hellwig, S.; Emde, F.; Raven, N.P.G.; Henke, M.; Logt, P. van der; Fischer, R.
Journal Article
1999Production of carcinoembryonic antigen (CEA) N-A3 domain in Pichia pastoris by fermentation
Hellwig, S.; Robin, F.; Drossard, J.; Raven, N.P.G.; Vaquero-Martin, C.; Shively, J.E.; Fischer, R.
Journal Article
1999Vergleichende Expression von Einzelketten-Antikörpern in E. coli, Pichia pastoris und Pflanzenzellen
Raven, N.
Thesis