Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins
Gresch, G.; Schenke, L.; Mladenov, R.; Zwirner, S.; Cremer, C.; Niesen, J.; Grieger, E.; Brümmendorf, T.; Jost, E.; Fischer, R.; Stockmeyer, B.; Barth, S.; Nachreiner, T.; Stein, C.
Journal Article
2017Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells
Woitok, M.; Klose, D.; Fiore, S. di; Richter, W.; Stein, C.; Gresch, G.; Grieger, E.; Barth, S.; Fischer, R.; Kolberg, K.; Niesen, J.
Journal Article
2017Efficient targeting of CD13 on cancer cells by the immunotoxin scFv13-ETA ' and the bispecific scFv [13xds16]
Grieger, E.; Gresch, G.; Niesen, J.; Woitok, M.; Barth, S.; Fischer, R.; Fendel, R.; Stein, C.
Journal Article
2017Generation of an artificial human B cell line test system using Transpo-mAb (TM) technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins
Klose, D.; Woitok, M.; Niesen, J.; Beerli, R.R.; Grawunder, U.; Fischer, R.; Barth, S.; Fendel, R.; Nachreiner, T.
Journal Article
2016The efficient elimination of solid tumor cells by EGFR-specific and HER2-specific scFv-SNAP fusion proteins conjugated to benzylguanine-modified auristatin F
Woitok, M.; Klose, D.; Niesen, J.; Richter, W.; Abbas, M.; Stein, C.; Fendel, R.; Bialon, M.; Püttmann, C.; Fischer, R.; Barth, S.; Kolberg, K.
Journal Article
2016A novel fully-human cytolytic fusion protein based on granzyme B shows in vitro cytotoxicity and ex vivo binding to solid tumors overexpressing the epidermal growth factor receptor
Niesen, J.; Hehmann-Titt, G.; Woitok, M.; Fendel, R.; Barth, S.; Fischer, R.; Stein, C.
Journal Article
2016SNAP-Tag Technology: A Useful Tool to Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments
Niesen, J.; Sack, M.; Seidel, M.; Fendel, R.; Barth, S.; Fischer, R.; Stein, C.
Journal Article
2015The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia
Mladenov, R.; Hristodorov, D.; Cremer, C.; Hein, L.; Kreutzer, F.; Stroisch, T.; Niesen, J.; Brehm, H.; Blume, T.; Brummendorf, T.H.; Jost, E.; Thepen, T.; Fischer, R.; Stockmeyer, B.; Barth, S.; Stein, C.
Journal Article
2015Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities
Niesen, J.; Stein, C.; Brehm, H.; Hehmann-Titt, G.; Fendel, R.; Melmer, G.; Fischer, R.; Barth, S.
Journal Article
2015Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein
Brehm, H.; Hristodorov, D.; Pardo, A.; Mladenov, R.; Niesen, J.; Fischer, R.; Tur, M.K.; Barth, S.
Journal Article
2014A CSPG4-specific immunotoxin kills rhabdomyosarcoma cells and binds to primary tumor tissues
Brehm, H.; Niesen, J.; Mladenov, R.; Stein, C.; Pardo, A.; Fey, G.; Helfrich, W.; Fischer, R.; Gattenlöhner, S.; Barth, S.
Journal Article
2014EpCAM-Selective Elimination of Carcinoma Cells by a Novel MAP-Based Cytolytic Fusion Protein
Hristodorov, D.; Amoury, M.; Mladenov, R.; Niesen, J.; Arens, K.; Berges, N.; Hein, L.; Fiore, S. di; Pham, A.T.; Huhn, M.; Helfrich, W.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2014In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells
Niesen, J.; Brehm, H.; Stein, C.; Berges, N.; Pardo, A.; Fischer, R.; Haaf, A. ten; Gattenlöhner, S.; Tur, M.K.; Barth, S.
Journal Article
2013SNAP-tag based agents for preclinical In vitro imaging in malignant diseases
Amoury, M.; Blume, T.; Brehm, H.; Niesen, J.; Tenhaef, N.; Barth, S.; Gattenlohner, S.; Helfrich, W.; Fitting, J.; Nachreiner, T.; Pardo, A.
Journal Article
2010Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein
Kampmeier, F.; Niesen, J.; Koers, A.; Ribbert, M.; Brecht, A.; Fischer, R.; Kießling, F.; Barth, S.; Thepen, T.
Journal Article