Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018Assessment of the cytotoxic and immunomodulatory effects of substances in human precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Konzok, Sebastian; Obernolte, Helena; Dehmel, Susann; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Zardo, Patrick; Warnecke, Gregor; Martin, Christian; Braun, Armin; Sewald, Katherina
Journal Article
2018Human teratoma-derived hematopoiesis is a highly polyclonal process supported by human umbilical vein endothelial cells
Philipp, Friederike; Selich, Anton; Rothe, Michael; Hoffmann, Dirk; Rittinghausen, Susanne; Morgan, Michael A.; Klatt, Denise; Glage, Silke; Lienenklaus, Stefan; Neuhaus, Vanessa; Sewald, Katherina; Braun, Armin; Schambach, Axel
Journal Article
2017Human effector memory T helper cells engage with mouse macrophages and cause Graft-versus-Host-like pathology in skin of humanized mice used in a nonclinical immunization study
Sundarasetty, Balasai; Volk, Valery; Theobald, Sebastian J.; Rittinghausen, Susanne; Schaudien, Dirk; Neuhaus, Vanessa; Figueiredo, Constanca; Schneider, Andreas; Gerasch, Laura; Mucci, Adele; Moritz, Thomas; Kaisenberg, Constantin von; Spineli, Loukia M.; Sewald, Katherina; Braun, Armin; Weigt, Henning; Ganser, Arnold; Stripecke, Renata
Journal Article
2015Precision-cut lung slices as an alternative model for repeated-dose inhalation toxicity
Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Syliva; Braun, Armin; Sewald, Katherina
Abstract
2014Alternative model for repeated dose inhalation toxicity using precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Witte, J.; Romberg, Susanne; Escher, Sylvia; Schaudien, Dirk; Braun, Armin; Sewald, Katherina
Abstract
2014A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung
Neuhaus, Vanessa; Chichester, Jessica A.; Ebensen, Thomas; Schwarz, Katharina; Cartman, Caitlin E.; Shoji, Yoko; Guzman, Carlos A.; Yusibov, Vidadi; Sewald, Katherina; Braun, Armin
Journal Article
2014New treatment strategies for respiratory diseases: Ex vivo and in vivo evaluation of pharmacological immunomodulations using a nanoparticle-based drug delivery system
Neuhaus, Vanessa
: Braun, Armin (Supervisor); Dittrich, Anna-Maria (Cosupervisor); Müller-Goymann, Christel (Cosupervisor)
Dissertation
2014Precision-cut lung slices as alternative to mimic inflammation, lung injury and bronchoconstriction after short and long-term maintenance in culture
Neuhaus, Vanessa; Schaudien, Dirk; Sewald, Katherina; Braun, Armin
Abstract
2014Toxicity testing of sildenafil base-loaded liposomes in in vitro and ex vivo models for pulmonary application
Paranjpe, Mukta; Neuhaus, Vanessa; Braun, Armin; Müller-Goymann, Christel C.
Journal Article
2014Use of rat precision-cut lung slices for long-term functional evaluation
Neuhaus, Vanessa; Braun, Armin; Sewald, Katherina
Abstract
2013Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique
Neuhaus, Vanessa; Schwarz, Katharina; Klee, Anna; Seehase, Sophie; Förster, Christine; Pfennig, Olaf; Jonigk, Danny; Fieguth, Hans-Gerd; Koch, Wolfgang; Warnecke, Gregor; Yusibov, Vidadi; Sewald, Katherina; Braun, Armin
Journal Article
2013Ein translationales LPS-Modell zur präklinischen Testung anti-inflammatorischer Substanzen im Weißbüschelaffen (Callithrix jacchus)
Seehase, Sophie; Switalla, Simone; Neuhaus, Vanessa; Zöller, Martina; Kaup, Franz Josef; Schlumbohm, Christina; Fuchs, E.; Lauenstein, Hans Dieter; Sewald, Katherina; Hohlfeld, Jens M.; Braun, Armin; Knauf, Sascha
Journal Article, Conference Paper
2012Ex vivo lung culture models of marmoset monkeys and humans for anti-inflammatory drug testing
Seehase, Sophie; Neuhaus, Vanessa; Kaup, Franz-Josef; Pfennig, O.; Förster, Christine; Hohlfeld, Jens Michael; Knauf, Sascha; Braun, Armin; Sewald, Katherina
Abstract
2012Immunotoxic characterization of a nanoparticle-based inhalable influenza vaccine in murine and human precision cut lung slices
Neuhaus, Vanessa; Schwarz, Katharina; Koch, Wolfgang; Sewald, Katherina; Yusibov, V.; Braun, Armin
Abstract
2012A new model for testing human specific anti-inflammatory drugs: LPS-induced lung inflammation in the common marmoset
Knauf, Sascha; Seehase, Sophie; Switalla, Simone; Neuhaus, Vanessa; Zöller, Martina; Kaup, Franz-Josef; Schlumbohm, Christina; Fuchs, Eberhard; Lauenstein, Hand D.; Sewald, Katherina; Hohlfeld, Jens Michael; Braun, Armin
Abstract