Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2011Fluorescence spectroscopy by detection of glucose concentrations in DMEM-solutions and its perspectives for non-invasive measurement
Abdallah, O.; Qananwah, Q.; Bolz, A.; Hansmann, J.; Hinderer, S.; Mertsching, H.
Conference Paper
2011Preclinical assessment of a tissue-engineered vasomotive human small-calibered vessel based on a decellularized xenogenic matrix: Histological and functional characterization
Heine, J.; Schmiedl, A.; Cebotari, S.; Mertsching, H.; Karck, M.; Haverich, A.; Kallenbach, K.
Journal Article
2011Tissue engineering human small-caliber autologous vessels using a xenogenous decellularized connective tissue matrix approach: Preclinical comparative biomechanical studies
Heine, J.; Schmiedl, A.; Cebotari, S.; Karck, M.; Mertsching, H.; Haverich, A.; Kallenbach, K.
Journal Article
2010IR spectroscopy vs. Raman scattering by measurement of glucose concentration
Abdallahs, O.; Hansmann, J.; Bolz, A.; Mertsching, H.
Conference Paper
2010A novel small-animal model for accelerated investigation of tissue-engineered aortic valve conduits
Kallenbach, K.; Sorrentino, S.; Mertsching, H.; Kostin, S.; Pethig, K.; Haverich, A.; Cebotari, S.
Journal Article
2010A system for the rapid detection of bacterial contamination in cell-based therapeutica
Bolwien, C.; Erhardt, C.; Sulz, G.; Thielecke, H.; Johann, R.; Pudlas, M.; Walles, H.; Mertsching, H.; Koch, S.
Conference Paper
2009Abloeseverfahren fuer adhaerente Zellen
Derichs, C.; Koropp, U.; Mertsching, H.; Kaufmann, M.; Hansmann, J.
Patent
2009Amino- and carboxy-functionalized nano- and microstructured surfaces for evaluating the impact of non-biological stimuli on adhesion, proliferation and differentiation of primary skin-cells
Borchers, K.; Kluger, P.J.; Panas, M.; Schober, L.; Tovar, G.E.M.; Mertsching, H.
Conference Paper
2009Amino- and carboxyfunctionalized nano- and microstructured surfaces for evaluating adhesion, proliferation and differentiation of primary keratinocytes
Kluger, P.; Panas, M.; Borchers, K.; Tovar, G.E.M.; Mertsching, H.
Abstract
2009Artificial vascularized human skin equivalent
Heymer, A.; Aubele, S.; Kaufmann, M.; Oddos, T.; Mertsching, H.
Abstract
2009Automatische Abtrennung von Partikeln aus einer Suspension
Pretzsch, F.; Koropp, U.; Mertsching, H.; Kaufmann, M.; Hansmann, J.
Patent
2009Basic research and clinical applications of non-hematopoietic stem cells, 4-5 April 2008, Tübingen, Germany
Schäfer, R.; Dominici, M.; Müller, I.; Horwitz, E.; Asahara, T.; Bulte, J.; Bieback, K.; Blanc, K. le; Bühring, H.J.; Capogrossi, M.C.; Dazzi, F.; Gorodetsky, R.; Henschler, R.; Handgretinger, R.; Kajstura, J.; Kluger, P.J.; Lange, C.; Luettichau, I. von; Mertsching, H.; Schrezenmeier, H.; Sievert, K.D.; Strunk, D.; Verfaillie, C.; Northoff, H.
Journal Article
2009Biological vascularized scaffold: Basis of a liver cell module
Linke, K.; Schanz, J.; Mertsching, H.
Abstract
2009Bioreactor technology in cardiovascular tissue engineering
Mertsching, H.; Hansmann, J.
Book Article
2009Bioreaktorsystem
Derichs, C.; Koropp, U.; Hansmann, J.; Kaufmann, M.; Mertsching, H.
Patent
2009Design of a GMP conform, disposable bioreactor for mechanically promoted engineering of cartilage
Fuhrmann, A.; Muehlfriede, S.; Knebel, G.; Schandar, M.; Mertsching, H.
Abstract
2009Development of a threedimensional trachea cell model
Hampel, M.; Dally, I.; Hansmann, J.; Mertsching, H.
Abstract
2009Discrimination of microorganisms and cells in tissue engineering by Raman spectroscopy
Koch, S.; Dreiling, M.; Gutekunst, M.; Bolwien, C.; Thielecke, H.; Mertsching, H.
Conference Paper
2009Dynamic intestinal tissue model to evaluate the absorption behaviour of different substances
Michaelis, J.; Engl, J.; Votteler, M.; Sawodny, B.; Mertsching, H.; Hirth, T.
Abstract
2009Europe's advanced therapy medicinal products: Chances and challenges. Editorial
Mertsching, H.; Walles, T.
Journal Article
2009Experimental tracheal patching using extracellular matrix scaffolds
Schanz, J.; Hampel, M.; Mertsching, H.; Walles, T.
Journal Article
2009Generation and transplantation of an autologous vascularized bioartificial human tissue
Mertsching, H.; Schanz, J.; Steger, V.; Schandar, M.; Schenk, M.; Hansmann, J.; Dally, I.; Friedel, G.; Walles, T.
Journal Article
2009Haut aus der Maschine
Kaufmann, M.; Mertsching, H.; Gehrmann, A.-L.
Journal Article
2009In vitro fascia model for hernia research
Pusch, K.; Spychaj, K.; Wohlert, S.; Emmel, J.; Mertsching, H.
Abstract
2009In vivo tissue engineering of heart valves using DNA-aptamers as capture molecules for circulating endothelial progenitor cells
Schleicher, M.; Kluger, P.; Hansmann, J.; Mack, A.F.; Fritze, O.; Mertsching, H.; Wendel, H.-P.; Ziemer, G.; Stock, U.A.
Abstract
2009Isolation, characterization and cryopreservation of neonatal, porcine cardiomyocytes
Ulmer, J.T.; Schandar, M.; Mertsching, H.
Abstract
2009Modulares Produktionssystem zur automatischen Herstellung von dreidimensionalen Gewebestrukturen
Mertsching, H.; Heymer, A.; Hansmann, J.; Kaufmann, M.; Reis, C.; Huchler, R.; Traube, A.; Stallkamp, J.; Pretzsch, F.; Derichs, C.; Koropp, U.; Marx, U.; Pilgermann, S.; Saxler, J.; Stolzing, A.
Patent
2009Pipettenkopf, Pipettiervorrichtung
Pretzsch, F.; Koropp, U.; Mertsching, H.; Kaufmann, M.; Hansmann, J.
Patent
2009Potential of predictive biomarkers for in vitro skin corrosion tests
Novosel, E.; Kaufmann, M.; Mertsching, H.
Abstract
2009Raman spectroscopy as a non-invasive tool for quality and sterility analysis of tissue engineering products
Dreiling, M.; Koch, S.; Bolwien, C.; Mertsching, H.
Abstract
2009Raman spectroscopy as a noninvasive tool for cellular characterization
Koch, S.; Bolwien, C.; Sulz, G.; Meides, A.; Mertsching, H.
Abstract
2009Raman spectroscopy: a non-invasive analysis tool for studies of living cells
Pudlas, M.; Koch, S.; Bolwien, C.; Mertsching, H.
Abstract
2009Regenerative Medizin in Deutschland: Großer Innovationssektor trifft auf hohe Hürden
Mertsching, H.; Walles, T.
Journal Article
2009Tissue factory: automated production of tissues
Heymer, A.; Kaufmann, M.; Pretzsch, F.; Bernhardt, F.; Traube, A.; Saxler, J.; Mertsching, H.
Abstract
2009A vascularised liver cell module as an alternative to animal experiments
Schanz, J.; Linke, K.; Mertsching, H.
Abstract
20083D Zellsysteme - In vitro Testsysteme als Alternativemethode zu Tierversuchen in der pharmazeutischen und chemischen Industrie
Michaelis, J.; Schanz, J.; Hansmann, J.; Hampel, M.; Mertsching, H.
Book Article
2008Adhesion, proliferation and differentiation of primary keratinocytes on chemically functionalized nano- and microstructured surfaces
Schweizer, P.; Borchers, K.; Riester, D.; Wojciukiewicz, D.; Tovar, G.; Mertsching, H.
Conference Paper
2008Bioartifical human tissues as test systems for basic and applied research: the vascularised liver module
Schanz, J.; Linke, K.; Hansmann, J.; Mertsching, H.
Journal Article, Conference Paper
2008Bioreaktorenentwicklung für das Tissue Engineering
Hansmann, J.; Mertsching, H.
Journal Article
2008Design of a GMP conform, disposable bioreactor for mechanically promoted engineering of cartilage
Furmann, A.; Muehlfriedel, S.; Schandar, M.; Mertsching, H.
Conference Paper
2008Development of a threedimensional Trachea Model
Hampel, M.; Hansmann, J.; Mertsching, H.
Conference Paper
2008Enrichment of primary human melanocytes on surfaces with carboxylic functionalisation
Schweizer, P.; Borchers, K.; Weimer, M.; Sciarratta, V.; Oehr, C.; Brunner, H.; Mertsching, H.
Conference Paper
2008Human skin equivalent as an alternative to animal testing
Mertsching, H.; Weimer, M.; Kersen, S.; Brunner, H.
Journal Article
2008Inducing in vitro angiogenesis for the generation of vascularized scaffolds
Schanz, J.; Hansmann, J.; Hampel, M.; Reis, C.; Michaelis, J.; Mertsching, H.
Conference Paper
2008Progenitor cells from adipose tissue: Cell source for the construction of novel in vitro test systems?
Schwegler, S.; Linke, K.; Mertsching, H.
Conference Paper
2008Rapid detection of bacterial contamination in cell or tissue cultures based on Raman spectroscopy
Bolwien, C.; Sulz, G.; Becker, S.; Thielecke, H.; Mertsching, H.; Koch, S.
Conference Paper
2008Schnelle Sterilitätskontrolle von Zell- und Gewebekulturen mittels Raman-Spektroskopie
Bolwien, C.; Sulz, G.; Becker, S.; Thielecke, H.; Mertsching, H.; Koch, S.
Conference Paper
2008Testsysteme für die Entwicklung von Tumordiagnoseverfahren
Thude, S.; Weimer, M.; Michaelis, J.; Mertsching, H.
Journal Article
2008Vascularized engineered transplants for reconstructive surgery: Implant generation and first clinical experiences
Walles, T.; Schanz, J.; Schandar, M.; Steger, V.; Friedel, G.; Mertsching, H.
Conference Paper
2008Verbesserte dreidimensionale biokompatible Gerüststruktur, die Nanopartikel beinhaltet
Brunner, H.; Mertsching, H.; Schweizer, P.; Weimer, M.; Weber, A.; Tovar, G.; Borchers, K.
Patent
2008Zellkulturtechniken, Zellmodelle und Tissue Engineering
Wobus, A.M.; Mertsching, H.
Book Article
2007Adhesion, proliferation and differentiation of primary keratinocytes on chemically functionalized nano- and microstructured surfaces
Schweizer, P.; Borchers, K.; Wojciukiewicz, D.; Riester, D.; Weimer, M.; Tovar, G.; Mertsching, H.
Journal Article
2007Characterisation of biological and artificial matrix by Raman spectroscopy
Koch, S.; Mertsching, H.
Conference Paper, Journal Article
2007Development of a 3D vascularised human tumour model
Michaelis, J.; Thude, S.; Mertsching, H.
Conference Paper, Journal Article
2007Development of a physiological three-dimensional intestinal test system
Michaelis, J.; Hansmann, J.; Mertsching, H.
Abstract
2007Engineered liver-like tissue on a capillarized matrix for applied research
Linke, K.; Schanz, J.; Hansmann, J.; Walles, T.; Brunner, H.; Mertsching, H.
Journal Article
2007Generation of a vascularized biomatrix as a scaffold for tissue engineering
Schanz, J.; Walles, T.; Mertsching, H.
Conference Paper, Journal Article
2007Health risk versus benefit
Peter, T.; Mertsching, H.
Journal Article
2007In vitro testing of different substances on a human 3D skin model
Weimer, M.; Brunner, H.; Mertsching, H.
Conference Paper, Journal Article
2007In vitro three-dimensional trachea model
Brenner, M.; Hansmann, J.; Mertsching, H.
Abstract
2007In vitro three-dimensional tubular trachea model
Brenner, M.; Hansmann, J.; Weimer, M.; Brunner, H.; Mertsching, H.
Conference Paper, Journal Article
2007In vitro toxicity assessment of carbon nanomaterial dispersions
Peter, T.; Vohrer, U.; Mertsching, H.
Abstract
2007Methods for the identification, characterization and isolation of adult stem cells
Thude, S.; Koch, S.; Rühl, M.; Mertsching, H.
Conference Paper, Journal Article
2007Modified surfaces and culture conditions to optimize adult stem cell adhesion, proliferation, differentiation and function
Mertsching, H.; Schweizer, P.; Schanz, J.; Weimer, M.; Brunner, H.
Conference Paper, Journal Article
2007Nanomaterials: Cytotoxic or biocompatible?
Peter, T.; Pusch, K.; Vohrer, U.; Weimer, M.; Mertsching, H.
Conference Paper, Journal Article
2007Neovaskularisation und Tissue Engineering vom komplexen Geweben
Mertsching, H.
Journal Article
2007The potential of bioartificial tissues in oncology research and treatment
Walles, T.; Weimer, M.; Linke, K.; Michaelis, J.; Mertsching, H.
Journal Article
2007Progenitor cells from the adipose tissue: Cell source for the construction of novel in vitro test systems?
Drescher, S.; Linke, K.; Mertsching, H.
Abstract
2007Strategies for scaffold vascularization in tissue engineering
Walles, T.; Mertsching, H.
Book Article
2007Studies of cell adhesion and cell differentiation by micro- and nanostructured surfaces
Schweizer, P.; Weimer, M.; Borchers, K.; Sciarratta, V.; Vohrer, U.; Oehr, C.; Brunner, H.; Mertsching, H.
Conference Paper, Journal Article
2007Tissue engineering, regenerative medicine and in vitro test systems - the department of cell and tissue engineering of Fraunhofer Institute for Interfacial Engineering and Biotechnology in Stuttgart
Anadere, I.; Mertsching, H.
Journal Article
2007Toxicology and health risk assesment of carbon nanomaterials (TRACER)
Schütz, W.; Michl, F.; Forero, S.; Mertsching, H.; Vohrer, U.
Conference Paper
2007Transplantation of myenteric and dorsal root neurones into acellular small intestinal submucous layer
Schäfer, K.H.; Maas-Omlor, S.; Rauch, U.; Mertsching, H.
Conference Paper, Journal Article
2007Vascularised liver cell module: A possible 3D test system for the evaluation of substance toxicity in vitro?
Schanz, J.; Linke, K.; Mertsching, H.
Abstract
2007A vascularised matrix: Scaffold for the development of a vascularised liver cell module
Linke, K.; Schanz, J.; Mertsching, H.
Conference Paper, Journal Article
20063D skin equivalent
Weimer, M.; Mertsching, H.; Brunner, H.
Abstract
2006Clinical application of tissue engineered human heart valves using autologous progenitor cells
Cebotari, S.; Lichtenberg, A.; Tudorache, I.; Hilfiker, A.; Mertsching, H.; Leyh, R.; Breymann, T.; Kallenbach, K.; Maniuc, I.; Batrinac, A.; Repin, O.; Maliga, O.; Ciubotaru, A.; Haverich, A.
Journal Article
2006Ex vivo generation of vascularized organ-like structures based on a biological matrix
Mertsching, H.; Schanz, J.; Hausmann, J.; Linke, K.; Brunner, H.
Abstract
2006Generation of a bioartificial fibromuscular tissue with autoregenerative capacities for surgical reconstruction
Biancosino, C.; Zardo, P.; Walles, T.; Wildfang, I.; Macchiarini, P.; Mertsching, H.
Journal Article
2006GMP-Herstellung erfolgreich outsourcen
Anadere, I.; Mertsching, H.
Journal Article
2006In vitro human model for tumor target screening in Cancer research
Mertsching, H.; Weimer, M.; Brunner, H.
Conference Paper
2006In vitro testing of the penetration and permeation of nanomaterials on an artificial human skin model
Weimer, M.; Mertsching, H.; Brunner, H.
Conference Paper
2006Isoliertes naturidentisches Kollagen
Xiong, X.; Mertsching, H.; Rupp, S.; Brunner, H.
Patent
2006Tissue engineering of viable pulmonary arteries for surgical correction of congenital heart defects
Leyh, R.G.; Wilhelmi, M.; Rebe, P.; Ciboutari, S.; Haverich, A.; Mertsching, H.
Journal Article
2006Vaskularisierte Trägersysteme für in vitro Testsysteme
Mertsching, H.; Hansmann, J.; Schanz, J.; Linke, K.; Brenner, M.; Michaelis, J.; Walles, T.
Conference Paper
2006Verfahren zur Anreicherung von Melanozyten mittels modifizierter Oberflaechen
Mertsching, H.; Schweizer, P.; Brunner, H.; Oehr, C.; Sciarratta, V.
Patent
2006Vorrichtung und Verfahren zur Analyse biologischer Proben
Mertsching, H.; Sulz, G.; Thielecke, H.; Bolwien, C.; Koch, S.
Patent
2005Biological vascularized matrix for bladder tissue engineering: Matrix preparation, reseeding technique and short-term implantation in a porcine model
Schultheiss, D.; Gabouev, A.I.; Cebotari, S.; Tudorache, I.; Walles, T.; Schlote, N.; Wefer, J.; Kaufmann, P.M.; Haverich, A.; Jonas, U.; Stief, C.G.; Mertsching, H.
Journal Article
2005Endothelialization and functional neointima on vascular grafts in humans: Reply
Walles, T.; Mertsching, H.
Journal Article
2005Engineering of a vascularized scaffold for artificial tissue and organ generation
Mertsching, H.; Walles, T.; Hofmann, M.; Schanz, J.; Knapp, W.H.
Journal Article
2005In vitro viability of human cavernosal endothelial and fibroblastic cells after exposure to papaverine/phentolamine and prostaglandin E1
Pilatz, A.; Schultheiss, D.; Gabouev, A.I.; Schlote, N.; Mertsching, H.; Jonas, U.; Stief, C.G.
Journal Article
2005Isolation of primary endothelial and stromal cell cultures of the corpus cavernosum penis for basic research and tissue engineering
Pilatz, A.; Schultheiss, D.; Gabouev, A.I.; Schlote, N.; Mertsching, H.; Jonas, U.; Stief, C.G.
Journal Article
2005Mit Schweinedarm geflickt
Mertsching, H.
Journal Article
2005Neointima in vascular prostheses: The jury is still out: Reply
Walles, T.; Mertsching, H.
Journal Article
2005Tissue remodeling in a bioartificial fibromuscular patch following transplantation in a human
Walles, T.; Biancosino, C.; Zardo, P.; Macciarini, P.; Gottlieb, J.; Mertsching, H.
Journal Article
2004Biologische vaskularisierte Matrix (BioVaM). Ein Ansatz zur Lösung des Perfusionsproblems im Tissue Engineering
Schultheiss, D.; Gabouev, A.I.; Kaufmann, P.M.; Schlote, N.; Mertsching, H.; Haverich, A.; Stief, C.G.; Jonas, U.
Journal Article
2004Could 37 degrees C storage temperature extend homovital valve allograft viability?
Baric, D.; Cebotari, S.; Mertsching, H.; Leyh, R.; Haverich, A.
Journal Article
2004Expansion of chondrocytes in a three-dimensional matrix for tracheal tissue engineering
Walles, T.; Giere, B.; Macchiarini, P.; Mertsching, H.
Journal Article
2004Experimental generation of a tissue-engineered functional and vascularized trachea
Walles, T.; Giere, B.; Hofmann, M.; Schanz, J.; Hofmann, F.; Mertsching, H.; Macchiarini, P.
Journal Article
2004Expression of epidermal growth-factor receptor in lymphangiomatosis: A new therapeutic target?
Mertsching, H.; Walles, T.; Bakker, G.; Wildfang, I.; Macchiarini, P.
Journal Article
2004First human transplantation of a bioengineered airway tissue
Macchiarini, P.; Walles, T.; Biancosino, C.; Mertsching, H.
Journal Article
2004Functional neointima characterization of vascular prostheses in human
Walles, T.; Görler, H.; Puschmann, C.; Mertsching, H.
Journal Article
2004Replacement of the trachea with an autologous aortic graft
Mertsching, H.; Walles, T.; Macchiarini, P.
Journal Article