Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix‐assisted laser desorption/ionization collision‐induced dissociation tandem mass spectrometry
Rühl, M.; Kühn, B.; Roos, J.; Maier, T.J.; Steinhilber, D.; Karas, M.
Journal Article, Conference Paper
2019Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ
Göbel, T.; Diehl, O.; Heering, J.; Merk, D.; Angioni, C.; Wittmann, S.K.; Buscato, E. la; Kottke, R.; Weizel, L.; Schader, T.; Maier, T.J.; Geisslinger, G.; Schubert-Zsilavecz, M.; Steinhilber, D.; Proschak, E.; Kahnt, A.S.
Journal Article
2018Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells
Kühn, B.; Brat, C.; Fettel, J.; Hellmuth, N.; Maucher, I.V.; Bulut, I.; Hock, K.J.; Grimmer, J.; Manolikakes, G.; Rühl, M.; Kühn, A.; Zacharowski, K.; Matrone, C.; Urbschat, A.; Roos, J.; Steinhilber, D.; Maier, T.J.
Journal Article
2018Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase
Roos, J.; Peters, M.; Maucher, I.V.; Kühn, B.; Fettel, J.; Hellmuth, N.; Brat, C.; Sommer, B.; Urbschat, A.; Piesche, M.; Vogel, A.; Proschak, E.; Blöcher, R.; Buscató, E.; Häfner, A.-K.; Matrone, C.; Werz, O.; Heidler, J.; Wittig, I.; Angioni, C.; Geisslinger, G.; Parnham, M.J.; Zacharowski, K.; Steinhilber, D.; Maier, T.J.
Journal Article
2017Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418
Maucher, I.V.; Rühl, M.; Kretschmer, S.B.M.; Hofmann, B.; Kühn, B.; Fettel, J.; Vogel, A.; Flügel, K.-T.; Manolikakes, G.; Hellmuth, N.; Häfner, A.-K.; Golghalyani, V.; Ball, A.K.; Piesche, M.; Matrone, C.; Geisslinger, G.; Parnham, M.J.; Karas, M.; Steinhilber, D.; Roos, J.; Maier, T.J.
Journal Article
2016Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors
Roos, J.; Grösch, S.; Werz, O.; Schröder, P.; Ziegler, S.; Fulda, S.; Paulus, P.; Urbschat, A.; Kühn, B.; Maucher, I.; Fettel, J.; Vorup-Jensen, T.; Piesche, M.; Matrone, C.; Steinhilber, D.; Parnham, M.J.; Maier, T.J.
Journal Article
20155-Lipoxygenase is a direct p53 target gene in humans
Gilbert, B.; Ahmad, K.; Roos, J.; Lehmann, C.; Chiba, T.; Ulrich-Rückert, S.; Smeenk, L.; Heeringen, S. van; Maier, T.J.; Groner, B.; Steinhilber, D.
Journal Article
2014Electrophilic Fatty Acid Species Inhibit 5-Lipoxygenase and Attenuate Sepsis-Induced Pulmonary Inflammation
Awwad, K.; Steinbrink, S.D.; Frömel, T.; Lill, N.; Isaak, J.; Häfner, A.K.; Roos, J.; Hofmann, B.; Heide, H.; Geisslinger, G.; Steinhilber, D.; Freeman, B.A.; Maier, T.J.; Fleming, I.
Journal Article
2013Cysteinyl leukotriene-receptor-1 antagonists interfere with PGE2 synthesis by inhibiting mPGES-1 activity
Kahnt, A.S.; Rörsch, F.; Diehl, O.; Hofmann, B.; Lehmann, C.; Steinbrink, S.D.; Angioni, C.; Geisslinger, G.; Grösch, S.; Steinhilber, D.; Maier, T.J.
Journal Article