Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells
Trümper, V.; Knethen, A. von; Preuß, A.; Ermilov, E.; Hackbarth, S.; Kuchler, L.; Gunne, S.; Schäfer, A.; Bornhütter, T.; Vereb, G.; Ujlaky-Nagy, L.; Brüne, B.; Röder, B.; Schindler, M.; Parnham, M.J.; Knape, T.
Journal Article
2019Maintaining hepatic PD-L1 expression improves sepsis survival in a murine polymicrobial sepsis model by tolerizing CTL
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fisslthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hoghardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Abstract
2019Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis
Knethen, A. von; Schäfer, A.; Kuchler, L.; Knape, T.; Christen, U.; Hintermann, E.; Fißlthaler, B.; Schröder, K.; Brandes, R.P.; Genz, B.; Abshagen, K.; Pützer, B.M.; Sha, L.K.; Weigert, A.; Syed, S.N.; Schulz, M.; Shah, A.M.; Ernst, A.; Putyrski, M.; Finkelmeier, F.; Pesic, M.; Greten, F.; Hogardt, M.; Kempf, V.A.J.; Gunne, S.; Parnham, M.J.; Brüne, B.
Journal Article
2017Apoptotic Diminution of Immature Single and Double Positive Thymocyte Subpopulations Contributes to Thymus Involution During Murine Polymicrobial Sepsis
Netzer, C.; Knape, T.; Kuchler, L.; Weigert, A.; Zacharowski, K.; Pfeilschifter, W.; Sempowski, G.; Parnham, M.J.; Brüne, B.; Knethen, A. von
Journal Article
2017Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis
Kuchler, L.; Sha, L.K.; Giegerich, A.K.; Knape, T.; Angioni, C.; Ferreiros, N.; Schmidt, M.V.; Weigert, A.; Brüne, B.; Knethen, A. von
Journal Article
2017PPARgamma as a putative stress marker in T cells following kidney transplantation
Aghajaanpour, R.; Brenneis, M.; Köhler, N.; Knape, T.; Büttner, S.; Kuchler, L.; Parnham, M.J.; Bruene, B.; Hauser, I.A.; Knethen, A. von
Abstract
2015Activation of the peroxisome proliferator-activated receptor γ counteracts sepsis-induced T cell cytotoxicity toward alloantigenic target cells
Knethen, A. von; Sha, L.K.; Knape, T.; Kuchler, L.; Giegerich, A.K.; Schulz, M.; Hauser, I.A.; Brüne, B.
Journal Article
2015Identification and characterisation of a prototype for a new class of competitive PPAR gamma antagonists
Knape, T.; Flesch, D.; Kuchler, L.; Sha, L.K.; Giegerich, A.K.; Labocha, S.; Ferreirós, N.; Schmid, T.; Wurglics, M.; Schubert-Zsilavecz, M.; Proschak, E.; Brüne, B.; Parnham, M.J.; Knethen, A. von
Journal Article
2015Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8+ T cell function by limiting GSH and Cys availability
Sha, L.K.; Sha, W.; Kuchler, L.; Daiber, A.; Giegerich, A.K.; Weigert, A.; Knape, T.; Snodgrass, R.; Schröder, K.; Brandes, R.P.; Brüne, B.; Knethen, A. von
Journal Article
2015MTTB: A new pharmacological concept for sepsis
Knape, T.; Flesch, D.; Kuchler, L.; Sha, L.K.; Giegerich, A.K.; Nova, N.V.; Labocha, S.; Ferreiros, N.; Schmid, T.; Wacker, M.; Wurglics, M.; Zsilavecz, S.; Proschak, E.; Brune, B.; Parnham, M.J.; Knethen, A. von
Abstract
2015Peroxisome Proliferator Activated Receptor Gamma Activation Counteracts Sepsis-Induced Cytotoxic T Cell Cytotoxicity Towards Alloantigenic Target Cells
Knethen, A. von; Knape, T.; Kuchler, L.; Schulz, M.; Hauser, I.A.; Brüne, B.
Abstract
2014Activation of the peroxisome proliferator activated receptor γ counteracts sepsis-induced T-cell cytotoxicity towards alloantigenic target cells
Knethen, A. von; Sha, L.K.; Knape, T.; Kuchler, L.; Giegerich, A.K.; Schulz, M.; Hauser, I.A.; Brüne, B.
Abstract
2014Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression
Giegerich, A.K.; Kuchler, L.; Sha, L.K.; Knape, T.; Heide, H.; Wittig, I.; Behrends, C.; Brüne, B.; Knethen, A. von
Journal Article
2014Sphingosine-1 phosphate promotes thymic atrophy during sepsis progression
Kuchler, L.; Sha, L.K.; Giegerich, A.K.; Knape, T.; Weigert, A.; Brüne, B.; Knethen, A. von
Abstract
2014SYNCRIP-dependent Nox2 mRNA destabilization impairs ROS formation in M2-polarized macrophages
Kuchler, L.; Giegerich, A.K.; Sha, L.K.; Knape, T.; Wong, M.S.K.; Schröder, K.; Brandes, R.P.; Heide, H.; Wittig, I.; Brüne, B.; Knethen, A. von
Journal Article