Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019BAL cell gene expression is indicative of outcome and airway basal cell involvement in idiopathic pulmonary fibrosis
Prasse, Antje; Binder, Harald; Schupp, Jonas C.; Kayser, Gian; Bargagli, Elena; Jäger, Benedikt; Hess, Moritz; Rittinghausen, Susanne; Vuga, Louis; Lynn, Heather; Violette, Shelia; Jung, Birgit; Quast, Karsten; Vanaudenaerde, Bart; Xu, Yan; Hohlfeld, Jens M.; Krug, Norbert; Herazo-Maya, Jose D.; Rottoli, Paola; Wuyts, Wim A.; Kaminski, Naftali
Journal Article
2019Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Jevnikar, Z.; Östling, J.; Ax, E.; Calven, J.; Thörn, K.; Israelsson, E.; Öberg, L.; Singhania, A.; Lau, L.C.K.; Wilson, S.J.; Ward, J.A.; Chauhan, A.; Sousa, A.R.; Meulder, B. de; Loza, M.J.; Baribaud, F.; Sterk, P.J.; Chung, K.F.; Sun, K.; Guo, Y.; Adcock, I.M.; Payne, D.; Dahlen, B.; Chanez, P.; Shaw, D.E.; Krug, Norbert; Hohlfeld, Jens M.; Sandström, T.; Djukanovic, R.; James, A.; Hinks, T.S.C.; Howarth, P.H.; Vaarala, O.; Geest, M. van; Olsson, H.; Adcock, I.M.; Ahmed, H.; Auffray, C.; Bakke, P.; Bansal, A.T.; Baribaud, F.; Bates, S.; Bel, E.H.; Bigler, J.; Bisgaard, H.; Boedigheimer, M.J.; Bonnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Caruso, M.; Chaiboonchoe, A.; Chanez, P.; Chung, F.K.; Compton, C.H.; Corfield, J.; D'Amico, A.; Dahlen, S.E.; De Meulder, B.; Djukanovic, R.; Erpenbeck, V.J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L.J.; Formaggio, E.; Fowler, S.J.; Frey, U.; Gahlemann, M.; Geiser, T.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hedlin,
Journal Article
2019Identification and prospective stability of electronic nose (eNose) - derived inflammatory phenotypes in patients with severe asthma
Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Zee, A.-H. Maitland-van der; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, N.J.; D'Amico, A.; Pennazza, G.; Santonico, M.; Lefaudeux, D.; Meulder, B. de; Auffray, C.; Bakke, P.S.; Caruso, M.; Chanez, P.; Chung, K.F.; Corfield, J.; Dahlén, S.-E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, Norbert; Musial, J.; Sun, K.; Riley, J.H.; Shaw, D.E.; Sandström, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.
Journal Article
2019Interferon Response Genes in Nasal Epithelium to Rhinovirus16 Challenge in Asthma Patients Links to Viral Clearance and Common Cold Scores
Ravi, A.; Chang, M.; Pol, M.A. van de; Yang, S.; Aliprantis, Antonios; Thornton, Bob; Hohlfeld, Jens M.; Sterk, Peter J.; Krug, Norbert; Lutter, René
Abstract
2019Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma
Tariq, K.; Schofield, James P.R.; Nicholas, Ben; Burg, Dominic; Brandsma, Joost; Bansal, Aruna T.; Wilson, Susan J.; Lutter, René; Fowler, Stephen J.; Bakke, Per; Caruso, Massimo; Dahlén, Barbro; Horvath, Ildiko; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandstrom, Thomas; Geiser, Thomas; Pandis, Ioannis; Sousa, Ana R.; Adcock, Ian M.; Shaw, Dominick E.; Auffray, Charles; Howarth, Peter H.; Sterk, Peter J.; Chung, Kian Fan; Skipp, Paul J.; Dimitrov, Borislav; Djukanovic, Ratko
Journal Article
2018A computational framework for complex disease stratification from multiple large-scale datasets
Meulder, Bertrand de; Lefaudeux, Diane; Bansal, Aruna T.; Mazein, Alexander; Chaiboonchoe, Amphun; Ahmed, Hassan; Balaur, Irina; Saqi, Mansoor; Pellet, Johann; Ballereau, Stephane; Lemonnier, Nathanaël; Sun, Kai; Pandis, Ioannis; Yang, Xian; Batuwitage, Manohara; Kretsos, Kosmas; Eyll, Jonathan van; Bedding, Alun; Davison, Timothy; Dodson, Paul; Larminie, Christopher; Postle, Anthony; Corfield, Julie; Djukanović, Ratko; Chung, Kian Fan; Adcock, Ian M.; Guo, Yi-Ke; Sterk, Peter J.; Manta, Alexander; Rowe, Anthony; Baribaud, Frédéric; Auffray, Charles; Badorrek, Philipp; Faulenbach, Cornelia; Braun, Armin; Hohlfeld, Jens; Krug, Norbert
Journal Article
2018Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
Emma, Rosalia; Bansal, Aruna T.; Kolmert, Johan; Wheelock, Craig E.; Dahlén, Sven-Erik; Loza, Matthew J.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Dahlén, Barbro; Bakke, Per S.; Chanez, Pascal; Fowler, Stephen J.; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Fleming, Louise J.; Djukanovic, Ratko; Howarth, Peter H.; Singer, Florian; Sousa, Ana R.; Sterk, Peter J.; Corfield, Julie; Pandis, Ioannis; Chung, Kian F.; Adcock, Ian M.; Lutter, René; Fabbella, Lorena; Caruso, Massimo
Journal Article
2018Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome
Burg, Dominic; Schofield, James P.R.; Brandsma, Joost; Staykova, Doroteya; Folisi, Caterina; Bansal, Aruna T.; Nicholas, Ben; Xian, Yang; Rowe, Anthony; Corfield, Julie; Wilson, Susan J.; Ward, Jonathan A.; Lutter, René; Fleming, Louise; Shaw, Dominick E.; Bakke, Per S.; Caruso, Massimo; Dahlén, Sven-Erik; Fowler, Stephen J.; Hashimoto, Simone; Horvath, Ildiko; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Singer, Florian; Sun, Kai; Pandis, Ioannis; Auffray, Charles; Sousa, Ana R.; Adcock, Ian M.; Chung, Kian F.; Sterk, Peter J.; Djukanovic, Ratko; Skipp, Paul J.
Journal Article
2018Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers
Brandsma, Joost; Goss, Victoria M.; Yang, Xian; Bakke, Per S.; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Chung, Kian Fan; Singer, Florian; Fleming, Louise J.; Sousa, Ana R.; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Djukanović, Ratko; Postle, Anthony D.
Journal Article
2018Measures of adherence in patients with severe asthma prescribed systemic steroids in the U-BIOPRED cohort
Alahmadi, Fahad; Simpson, Andrew; Gomez, Christina; Wheelock, Craig; Shaw, Dominick E.; Fleming, Louise; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R.; Knowles, Richard; Bansal, Aruna T.; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per; Caruso, Massimo; Chanez, Pascal; Dahlen, Babro; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sandstrom, Thomas; Singer, Florian; Wagers, Scott; Adcock, Ian M.; Djukanović, Ratko; Chung, Kian Fan; Sterk, Peter J.; Dahlén, Sven-Erik; Fowler, Stephen J.
Abstract
2018Periostin expression in the U-BIOPRED severe asthma bronchoscopy cohort
Wilson, Susan Jane; Faruqi, Ali; Ward, Jonathan A.; Norman, Jenny; Sousa, Ana R.; Corfield, Julie; Sterk, Peter J.; Chung, Fan; Djukanović, Ratko; Dahlén, Barbro; Chanez, Pascal; Shaw, Dominick E.; Krug, Norbert; Sandstrom, Thomas; Howarth, Peter; Holweg, Cecile
Abstract
2018Rhinovirus challenge in asthmatics and healthy volunteers to evaluate the safety and appropriate dose of a GMP human rhinovirus 16 preparation for challenge studies in mild-moderate asthmatics taking ICS
Krug, Norbert; Hohlfeld, Jens M.; Aliprantis, Antonios; Carayannopoulos, Leonidas; Bautmans, An; Robberechts, Martine; Lepeleire, Inge de; Ziehr, Holger; Singh, Dave; Diamant, Zuzana; Yang, Shan; Fitch, Neil; Thornton, Bob; Sterk, Peter J.; Lutter, René
Abstract
2018Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: An exploratory analysis
Takahashi, Kentaro; Pavlidis, Stelios; Ng Kee Kwong, Francois; Hoda, Uruj; Rossios, Christos; Sun, Kai; Loza, Matthew; Baribaud, Fred; Chanez, Pascal; Fowler, Steve J.; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlén, Barbro; Dahlén, Sven-Erik; Krug, Norbert; Sandström, Thomas; Shaw, Dominick E.; Lutter, René; Bakke, Per; Fleming, Louise J.; Howarth, Peter H.; Caruso, Massimo; Sousa, Ana R.; Corfield, Julie; Auffray, Charles; Meulder, Bertrand de; Lefaudeux, Diane; Djukanovic, Ratko; Sterk, Peter J.; Guo, Yike; Adcock, Ian M.; Chung, Kian Fan
Journal Article
2018Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA
Schofield, James P.R.; Bigler, Jeanette; Boedigheimer, Michael; Affleck, Karen; Taylor, Adam; Pavlidis, Stelios; Riley, John H.; Strazzeri, Fabio; Roberts, Graham; Brandsma, Joost; Bansal, Aruna T.; Nicholas, Ben; Xian, Yang; Rowe, Anthony; Corfield, Julie; Wilson, Susan J.; Ward, Jonathan A.; Lutter, René; Fleming, Louise; Shaw, Dominick E.; Per, Bakke; Caruso, Massimo; Dahlén, Sven-Erik; Fowler, Stephen J.; Hashimoto, Simone; Horváth, Ildikó; Howarth, Peter; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandstrom, Thomas; Singer, Florian; Sun, Kai; Pandis, Ioannis; Auffray, Charles; Meulder, Bertrand de; Lefaudeux, Diane; Knowles, Richard; Fitch, Neil; Sousa, Ana R.; Adcock, Ian M.; Chung, Kian Fan; Sterk, Peter J.; Skipp, Paul; Djukanović, Ratko
Abstract
2018U-BIOPRED accessible handprint: Combining omics platforms to identify stable asthma subphenotypes
Meulder, Bertrand de; Yen, Romain Tching Chi; Li, Chuan-Xing; Wheelock, Asa; Chung, Kian Fan; Adcock, Ian M.; Djukanović, Ratko; Wagers, Scott; Riley, John; Erpenbeck, Veit J.; Bakke, Per; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominic; Singer, Florian; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Baribaud, Frédéric; Auffray, Charles
Abstract
2017Specificity and reproducibility of nasal biomarkers in patients with allergic rhinitis after allergen challenge chamber exposure
Badorrek, Philipp; Müller, Meike; Koch, Wolfgang; Hohlfeld, Jens M.; Krug, Norbert
Journal Article
2017A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED
Kuo, C.H.S.; Pavlidis, S.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Hoda, U.; Rossios, C.; Souse, A.; Wilson, S.J.; Howarth, P.; Dahlen, B.; Dahlen, S.E.; Chanez, P.; Shaw, D.; Krug, Norbert; Sandström, T.; Meulder, B. de; Lefaudeux, D.; Fowler, S.; Fleming, L.; Corfield, J.; Auffray, C.; Sterk, P.J.; Djukanovic, R.; Guo, Y.K.; Adcock, I.M.; Chung, K.F.
Journal Article
2016Safety, efficacy and repeatability of a novel house dust mite allergen challenge technique in the Fraunhofer allergen challenge chamber
Lüer, Katrin; Biller, Heike; Casper, Anja; Windt, Horst; Müller, Meike; Badorrek, Philipp; Haefner, Dietrich; Framke, Theodor; Koch, A.; Ziehr, Holger; Krug, Norbert; Koch, Wolfgang; Hohlfeld, Jens M.
Journal Article
2016Severe asthma exists despite suppressed tissue inflammation: Findings of the U-BIOPRED study
Wilson, Susan J.; Ward, Jonathan A.; Sousa, Ana R.; Corfield, Julie; Bansal, Aruna T.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Loza, Matthew J.; Baribaud, Frédéric; Fitch, Neil; Sterk, Peter J.; Chung, Kian Fan; Gibeon, David; Sun, Kai; Guo, Yi-Ke; Adcock, Ian M.; Djukanovic, Ratko; Dahlén, Barbro; Chanez, Pascal; Shaw, Dominick E.; Krug, Norbert; Hohlfeld, Jens; Sandström, Thomas; Howarth, Peter H.
Journal Article
2015Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
Krug, Norbert; Hohlfeld, Jens Michael; Kirsten, Anne-Marie; Kornmann, Oliver; Beeh, Kai-Michael; Kappeler, Dominik; Korn, Stephanie; Ignatenko, Stanislav; Timmer, Wolfgang; Rogon, Cordelia; Zeitvogel, Jana; Zhang, Nan; Bille, Joachim; Homburg, Ursula; Turowska, Agnieszka; Bachert, Claus; Werfel, Thomas; Buhl, Roland; Renz, Jonas; Garn, Holger; Renz, Harald
Journal Article
2015Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Shaw, Dominick E.; Sousa, Ana R.; Fowler, Stephen J.; Fleming, Louise J.; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T.; Bel, Elisabeth H.; Auffray, Charles; Compton, Chris H.; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlén, Sven-Erik; Dyson, Kerry; Frey, Urs; Geiser, Thomas; Gerhardsson de Verdier, Maria; Gibeon, David; Guo, Yi-Ke; Hashimoto, Simone; Hedlin, Gunilla; Jeyasingham, Elizabeth; Hekking, Pieter-Paul W.; Higenbottam, Tim; Horváth, Ildikó; Knox, Alan J.; Krug, Norbert; Erpenbeck, Veit J.; Larsson, Lars X.; Lazarinis, Nikos; Matthews, John G.; Middelveld, Roelinde; Montuschi, Paolo; Musial, Jacek; Myles, David; Pahus, Laurie; Sandström, Thomas; Seibold, Wolfgang; Singer, Florian; Strandberg, Karin; Vestbo, Jorgen; Vissing, Nadja; Garnier, Christophe von; Adcock, Ian M.; Wagers, Scott; Rowe, Anthony; Howarth, Peter; Wagener, Ariane H.; Djukanovic, Ratko; Sterk, Peter J.; Chung, Kian Fan
Journal Article
2015Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis
Badorrek, Philipp; Hohlfeld, Jens M.; Krug, Norbert; Joshi, Abhijeet; Raut, Atul
Journal Article
2015Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers
Holz, Olaf; Tan, Lisa; Schaumann, Frank; Müller, Meike; Scholl, Dorothea; Hidi, R.; McLeod, Alison; Krug, Norbert; Hohlfeld, Jens M.
Journal Article
2015Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: A proof of concept study
Renne, Julius; Hinrichs, Jan; Schönfeld, Christian; Gutberlet, Marcel; Winkler, Carla; Faulenbach, Cornelia; Jakob, Peter; Schaumann, Frank; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Journal Article
2015Pharmacological MRI (phMRI) of the human central nervous system
Lanfermann, Heinrich; Schindler, Chris; Jordan, Jens; Krug, Norbert; Raab, Peter
Journal Article
2015Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma
Homburg, Ursula; Renz, Harald; Timmer, Wolfgang; Hohlfeld, Jens M.; Seitz, Friedeborg; Lüer, Katrin; Mayer, Alexandra; Wacker, Anja; Schmidt, Oliver; Kuhlmann, Jens; Turowska, Agnieszka; Roller, Julia; Kutz, Klaus; Schlüter, Gerhard; Krug, Norbert; Garn, Holger
Journal Article
2014Cell counting in human endobronchial biopsies - disagreement of 2D versus 3D morphometry
Bratu, Vlad A.; Erpenbeck, Veit J.; Fehrenbach, Antonia; Rausch, Tanja; Rittinghausen, Susanne; Krug, Norbert; Hohlfeld, Jens M.; Fehrenbach, Heinz
Journal Article
2014Dose-range finding of natural birch pollen exposure in patients with seasonal allergic rhinitis in the Fraunhofer Environmental Challenge Chamber
Lüer, Katrin; Windt, Horst; Schwarz, Katharina; Badorrek, Philipp; Sebastian, Ramona; Haefner, Dietrich; Koch, Wolfgang; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014The effect of controlled exposure to grass pollen in an environmental challenge chamber on dermal symptoms in patients with atopic dermatitis
Heratizadeh, Annice; Badorrek, Philipp; Niebuhr, Margarete; Erpenbeck, Veit Johannes; Lösche, C.; Krug, Norbert; Hohlfeld, Jens Michael; Werfel, Thomas
Abstract
2014Effect of sample processing on the analysis of IL4, IL5, and IL13 in sputum supernatants
Holz, Olaf; Müller, Meike; Ignatenko, Stanislav; Kappeler, Dominik; Buhl, Roland; Beeh, Kai-Michael; Kornmann, Oliver; Kirsten, Anne; Homburg, Ursula; Garn, Holger; Krug, Norbert; Hohlfeld, Jens Michael
Abstract
2014Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: Results of a double-blinded randomized cross-over clinical pilot study
Schaumann, Frank; Frömke, Cornelia; Dijkstra, Dorothea; Alessandrini, Francesca; Windt, Horst; Karg, Erwin; Müller, Meike; Winkler, Carla; Braun, Armin; Koch, Armin; Hohlfeld, Jens Michael; Behrendt, Heidrun; Schmid, Otmar; Koch, Wolfgang; Schulz, Holger; Krug, Norbert
Journal Article
2014Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis
Krug, Norbert; Gupta, Abhy; Badorrek, Philipp; Koennen, Ruediger; Mueller, Meike; Pivovarova, Anna; Hilbert, James; Wetzel, Kristiane; Hohlfeld, Jens M.; Wood, Chester
Journal Article
2014Omalizumab in patients with allergic (IgE-mediated) asthma and IgE/bodyweight combinations above those in the initially approved dosing table
Kornmann, Oliver; Watz, Henrik; Fuhr, Rainard; Krug, Norbert; Erpenbeck, Veit J.; Kaiser, Guenther
Journal Article
2014Phase-contrast MRI for detection of mild systemic hemodynamic response after segmental allergen challenge in asthmatic patients
Hinrichs, Jan; Schaumann, Frank; Renne, Julius; Schönfeld, Christian; Faulenbach, Cornelia; Winkler, Carla; Gutberlet, Marcel; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens M.; Vogel-Claussen, Jens
Journal Article
2014Prevalence and phenotypic characteristics of severe adult-onset asthma in the U-Biopred cohort
Hekking, Pieter-Paul; Wagener, Ariane H.; Sousa, Ana R.; Fowler, Stephen J.; Bakke, Per; Frey, Urs; Krug, Norbert; Hashimoto, Simone; Woodcock, Ashley; Chanez, Pascal; Montuschi, Paolo; Bisgaard, Hans; Corfield, Julie; Howarth, Peter H.; Djukanovic, Ratko; Chung, Kian Fan; Fleming, Louise; Riley, John; Jeyasingham, Elisabeth; Fichtner, Klaus; Rowe, Anthony; Roberts, Graham; Singer, Florian; Geiser, Thomas; Horvath, Ildiko; Riccardo, Polosa; Vissing, Nadja H.; Dahlen, Babro; Musial, Jacek; Murray, Clare S.; Myles, David; Compton, Chris; Higenbottam, Tim W.; Vestbo, J.; Pahus, Laurie; Larsson, Lars; Sandstrom, Thomas; Shaw, Dominic; Wagers, Scott S.; Sterk, Peter J.; Bansal, Aruna T.; Bel, Elisabeth
Abstract
2014Quantification of pulmonary inflammation after segmental allergen challenge using turbo-inversion recovery-magnitude magnetic resonance imaging
Vogel-Claussen, Jens; Renne, Julius; Hinrichs, Jan; Schönfeld, Christian; Gutberlet, Marcel; Schaumann, Frank; Winkler, Carla; Faulenbach, Cornelia; Krug, Norbert; Wacker, Frank; Hohlfeld, Jens Michael
Journal Article
2014Severe asthma patients on oral corticosteroid therapy as a distinct phenotype: The european U-BIOPRED cohort
Chung, Kian F.; Gibeon, David; Sousa, Ana R.; Corfield, Julie; Shaw, Dominick E.; Fowler, Stephen J.; Fleming, Louise J.; Riley, John; Jeyasingham, Elisabeth; Rowe, Anthony; Fichtner, Klaus; Roberts, Graham; Bakke, Per; Garnier, Christophe von; Horvath, Ildiko; Riccardo, Polosa; Krug, Norbert; Dahlen, Barbaro; Musial, Jacek; Pahus, Laurie; Myles, David; Compton, Chris; Higenbottam, Tim W.; Montuschi, Paolo; Larsson, Lars; Sandstrom, Thomas; Wagers, Scott S.; Howarth, Peter H.; Bel, Elisabeth; Bansal, Aruna T.; Djukanovic, Ratko; Sterk, Peter J.
Abstract
2013Associated factors with persistent airflow limitation in asthma in U-BIOPRED
Wagener, A.H.; Gibeon, D.; Yang, X.; Sousa, A.R.; Corfield, J.; Shaw, D.E.; Fowler, S.; Flemming, L.J.; Riley, J.; Jeyasingham, E.; Rowe, A.; Fichtner, K.; Robberts, G.; Bakke, P.; Singer, T.; Geiser, T.; Frey, U.; Horvarth, I.; Polosa, R.; Bonnelykke, K.; Krug, Norbert; Middelveld, R.; Dahlen, S.-E.; Dahlen, B.; Hedlin, G.; Hashimoto, S.; Nordlund, B.; Musial, J.; Woodcock, A.; Murray, C.S.; Pahus, L.; Chanez, P.; Myles, D.; Compton, C.; Higenbottam, T.W.; Montuschi, P.; Vestbo, J.; Larsson, L.; Sandstrom, T.; Bisgaard, H.; Wagers, S.S.; Howarth, P.H.; Bel, E.H.; Djukanovic, R.; Chung, K.F.; Sterk, P.J.
Journal Article, Conference Paper
2013Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices
Switalla, Simone; Knebel, Jan; Ritter, Detlef; Dasenbrock, Clemens; Krug, Norbert; Braun, Armin; Sewald, Katherina
Journal Article
2013Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development
Janssen, Ole; Schaumann, Frank; Holz, Olaf; Lavae-Mokhtari, Bianca; Welker, Lutz; Winkler, Carla; Biller, Heike; Krug, Norbert; Hohlfeld, Jens M.
Journal Article
2013Safety profile and pharmacokinetics of an inhaled GATA-3-specific DNAzyme in a phase Ib study in patients with stable allergic asthma
Hohlfeld, Jens; Lüer, Katrin; Krug, Norbert; Turowska, Agnieszka; Renz, Harald; Garn, Holger; Homburg, Ursula
Journal Article, Conference Paper