Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Analyses of association of psoriatic arthritis and psoriasis vulgaris with functional NCF1 variants
Löhr, S.; Ekici, A.B.; Uebe, S.; Büttner, C.; Köhm, M.; Behrens, F.; Böhm, B.; Sticherling, M.; Schett, G.; Simon, D.; Mössner, R.; Nimeh, A.; Oji, V.; Assmann, G.; Rech, J.; Holmdahl, R.; Burkhardt, H.; Reis, A.; Hüffmeier, U.
Journal Article
2019Immunogenicity assay development and validation for biological therapy as exemplified by ustekinumab
Mojtahed Poor, S.; Ulshöfer, T.; Gabriel, L.A.; Henke, M.; Köhm, M.; Behrens, F.; Geisslinger, G.; Parnham, M.J.; Burkhardt, H.; Schiffmann, S.
Journal Article
2018Stellenwert der Kombination von Biologika mit Methotrexat in der Behandlung der Psoriasisarthritis - Fragen bleiben offen
Dauth, S.; Köhm, M.; Rossmanith, T.; Herrmann, E.; Lehn, A.; Burkhardt, H.; Behrens, F.
Journal Article
2017Comparative Analysis of Achievement of Individual Important Response Measured By DAS28dcrit in a Randomized Head-to-Head Trial of Tocilizumab Vs. Adalimumab in Active Rheumatoid Arthritis
Koehm, M.; Hofmann, M.; Lüthje, R.; McIntosh, M.; Abraham, V.; Gabay, C.; Kavanaugh, A.; Burkhardt, H.; Behrens, F.
Abstract
2017Detection of Clinical Signs of Arthritis and Subclinical Evidence of Inflammation in Psoriasis Patients with Risk for Arthritis: Value of Clinical Examination, Ultrasound and Fluorescence-Optical Imaging - Results from the Prospective Multicentre Xciting Study
Koehm, M.; Rossmanith, T.; Langer, H.E.; Backhaus, M.; Burmester, G.R.; Wassenberg, S.; Köhler, B.; Burkhardt, H.; Behrens, F.
Abstract
2017Impact of rituximab in combination with leflunomide and rituximab retreatment with two different dosages on patient-reported outcomes: results from a multicenter randomized placebo controlled investigator initiated clinical trial in active rheumatoid arthritis (AMARA-STUDY)
Köhm, M.; Rossmanith, T.; Dauth, S.; Alten, R.; Aringer, M.; Backhaus, M.; Burmester, G.; Feist, E.; Kellner, H.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Tony, H.P.; Wassenberg, S.; Burkhardt, H.; Behrens, F.
Abstract
2017Psoriasisarthritis. Aktuelle therapeutische Standards
Köhm, M.; Behrens, F.
Journal Article
2016Achievement of individual important response measured by Das28dcrit in active rheumatoid arthritis when treated with tocilizumab
Behrens, F.; Köhm, M.; Hofmann, M.; Fliedner, G.; Specker, C.; Burkhardt, H.
Abstract
2016Anti-citrullinated protein antibodies are linked to erosive disease in an observational study of patients with psoriatic arthritis
Behrens, F.; Koehm, M.; Thaci, D.; Gnann, H.; Greger, G.; Wittig, B.M.; Burkhardt, H.
Journal Article
2016Association analysis of psoriasis vulgaris and psoriatic arthritis with loss-of-function mutations in IL36RN in German patients
Löhr, S.; Uebe, S.; Behrens, F.; Böhm, B.; Köhm, M.; Traupe, H.; Oji, V.; Burkhardt, H.; Reis, A.; Hüffmeier, U.
Journal Article
2016Association of Improvement in Pain with Therapeutic Response as Determined by Individual Improvement Criteria in Patients with Rheumatoid Arthritis
Scharbatke, E.C.; Behrens, F.; Schmalzing, M.; Koehm, M.; Greger, G.; Gnann, H.; Burkhardt, H.; Tony, H.-P.
Journal Article
2016Characterization of Ra patients with a DAS28 response to adalimumab therapy by improvement in pain: A german nonintervention study
Köhm, M.; Scharbatke, E.; Stemmler, E.; Greger, G.; Behrens, F.; Wittig, B.
Abstract
2016Detection of psoriatic arthritis in patients with psoriasis in daily routine care using questionnaires for diagnosis of psoriatic arthritis and fluorescence-optical imaging technique
Köhm, M.; Rossmanith, T.; Langer, H.E.; Burmester, G.; Wassenberg, S.; Kaesser, U.; Backhaus, M.; Burkhardt, H.; Behrens, F.
Abstract
2016Does concomitant methotrexate with adalimumab influence treatment outcomes in patients with psoriatic arthritis? Data from a large observational study
Behrens, F.; Koehm, M.; Arndt, U.; Wittig, B.M.; Greger, G.; Thaci, D.; Scharbatke, E.; Tony, H.-P.; Burkhardt, H.
Journal Article
2016The Predict Study: low risk for digital ulcer development in patients with systemic sclerosis with increasing disease duration and lack of topoisomerase-1 antibodies
Hunzelmann, N.; Riemekasten, G.; Becker, M.O.; Moinzadeh, P.; Kreuter, A.; Melchers, I.; Mueller-Ladner, U.; Meier, F.; Worm, M.; Lee, H.; Herrgott, I.; Pfeiffer, C.; Fierlbeck, G.; Henes, J.; Juche, A.; Zeidler, G.; Mensing, H.; Günther, C.; Sárdy, M.; Burkhardt, H.; Koehm, M.; Kuhr, K.; Krieg, T.; Sunderkötter, C.
Journal Article
2016Psoriatic arthritis
Koehm, M.; Behrens, F.
Book Article
2016Rituximab in combination with leflunomide: Results from a multicenter randomized placebo controlled investigator initiated clinical trial in active rheumatoid arthritis (Amara-Study)
Behrens, F.; Rossmanith, T.; Köhm, M.; Alten, R.; Aringer, M.; Backhaus, M.; Baerwald, C.; Burmester, G.; Feist, E.; Kellner, H.; Krüger, K.; Müller-Ladner, U.; Rubbert-Roth, A.; Tony, H.P.; Wassenberg, S.; Burkhardt, H.
Abstract
2016Tight-Control der Entzündungsaktivität in der Therapie der frühen Psoriasisarthritis Eine sinnvolle Therapiestrategie zur Verbesserung der Patientenversorgung?
Köhm, M.
Journal Article
2015Anti-TNF-α therapy as an evidence-based treatment option for different clinical manifestations of psoriatic arthritis
Köhm, M.; Burkhardt, H.; Behrens, F.
Journal Article
2015Brauchen wir noch klinische Studien in der Rheumatologie?
Henkemeier, U.; Alten, R.; Bannert, B.; Baraliakos, X.; Behrens, F.; Heldmann, F.; Kiltz, U.; Köhm, M.; König, R.; Leipe, J.; Müller-Ladner, U.; Rech, J.; Riechers, E.; Rubbert-Roth, A.; Schmidt, R.E.; Schulze-Koops, H.; Specker, C.; Tausche, A.-K.; Wassenberg, S.; Witt, M.; Witte, T.; Zernicke, J.; Burkhardt, H.
Journal Article
2015Non-response to Antitnf treatment in psoriatic arthritis can be predicted by an objective automated measurement of fluorescence-signal intensities in fluorescence-optical imaging technique - the first interims analysis of the xplore-study
Koehm, M.; Rossmanith, T.; Henkemeier, U.; Aries, P.; Alten, R.; Langer, H.-E.; Burkhardt, H.; Behrens, F.
Abstract
2015Pharmakotherapie der Psoriasisarthritis
Köhm, M.; Behrens, F.
Journal Article
2015Predictors of therapeutic response in ankylosing spondylitis patients initiating therapy with adalimumab in a german non-interventional study
Koehm, M.; Behrens, F.; Scharbatke, E.C.; Schmalzing, M.; Gnann, H.; Greger, G.; Wittig, B.; Tony, H.P.; Burkhardt, H.
Abstract
2014Effects of methotrexate on anti-TNF treatment in rheumatoid arthritis
Schmalzing, M.; Behrens, F.; Scharbatke, E.C.; Koehm, M.; Wittig, B.; Greger, G.; Burkhardt, H.; Tony, H.P.
Abstract
2014Rheumatoid factor status is a predictor of osteoporosis in patients with psoriatic arthritis
Behrens, F.; Koehm, M.; Scharbatke, E.C.; Wittig, B.; Schmalzing, M.; Gnann, H.; Lorenz, H.M.; Thaci, D.; Burkhardt, H.
Abstract
2014SAT0358 impact of methotrexate on anti-TNF treatment in psoriatic arthritis? An in-depth analysis of a large prospective observational study with adalimumab
Behrens, F.; Köhm, M.; Arndt, U.; Wittig, B.; Greger, G.; Thaci, D.; Scharbatke, E.; Tony, H.P.; Burkhardt, H.
Abstract
2014Validity of additional use of optical immunofluorescence imaging technique (Xiralite®) in detection of active psoriatic arthritis and measurement of disease activity in patients with psoriasis and psoriatic arthritis
Köhm, M.; Roßmanith, T.; Burkhardt, H.; Behrens, F.
Abstract
2013Development and validation of a new disease activity score in 28 joints–based treatment response criterion for rheumatoid arthritis
Behrens, F.; Tony, H.-P.; Alten, R.; Kleinert, S.; Scharbatke, E.C.; Köhm, M.; Gnann, H.; Tams, J.; Greger, G.; Burkhardt, H.
Journal Article
2013DMARD-Versager vs. TNF-Versager bei aktiver Psoriasis-Arthritis: Vergleichende Untersuchung zu Krankheitscharakteristika aus einer großen prospektiven Observationsstudie vor Einleitung einer Therapie mit Adalimumab
Behrens, F.; Köhm, M.; Thaci, D.; Krummel-Lorenz, B.; Greger, G.; Wittig, B.; Burkhardt, H.
Abstract
2013Gibt es eine Assoziation zwischen Haut- und Gelenkmanifestation bei Patienten mit Psoriasis-Arthritis? – Datenanalyse einer deutschen nichtinterventionellen Studie mit Adalimumab bei aktiver Psoriasis-Arthritis
Köhm, M.; Behrens, F.; Thaci, D.; Krummel-Lorenz, B.; Greger, G.; Wittig, B.; Burkhardt, H.
Abstract
2013Personalisierte Medizin bei Zytokin-gerichteten Therapien
Behrens, F.; Köhm, M.
Journal Article
2013Wirksamkeit von Adalimumab bei aktiver Psoriasis-Arthritis und unzureichendem Ansprechen auf bis zu drei Anti-TNF-Vortherapien
Köhm, M.; Behrens, F.; Thaci, D.; Krummel-Lorenz, B.; Greger, G.; Wittig, B.; Burkhardt, H.
Abstract