Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021Advanced flow cytometry assays for immune monitoring of CAR-T cell applications
Blache, Ulrich; Weiss, Ronald; Boldt, Andreas; Kapinsky, Michael; Blaudszun, André-René; Quaiser, Andrea; Pohl, Annabelle; Miloud, Tewfik; Burgaud, Mégane; Vucinic, Vladan; Platzbecker, Uwe; Sack, Ulrich; Fricke, Stephan; Koehl, Ulrike
Journal Article
2021CAR-T-Zellen als Arzneimittel für neuartige Therapien (Advanced Therapy Medicinal Products)
Koehl, Ulrike; Abken, Hinrich
Journal Article
2021Distinct immune signatures indicative of treatment response and immune-related adverse events in melanoma patients under immune checkpoint inhibitor therapy
Reschke, Robin; Gussek, Philipp; Boldt, Andreas; Sack, Ulrich; Koehl, Ulrike; Lordick, Florian; Gora, Thomas; Kreuz, Markus; Reiche, Kristin; Simon, Jan-Christoph; Ziemer, Mirjana; Kunz, Manfred
Journal Article
2021Distinct molecular mechanisms of altered HLA class II expression in malignant melanoma
Meyer, Stefanie; Handke, Diana; Müller, Anja; Biehl, Katharina; Kreuz, Markus; Bukur, Jürgen; Koehl, Ulrike; Lazaridou, Maria-Filothei; Berneburg, Mark; Steven, André; Massa, Chiara; Seliger, Barbara
Journal Article
2021Flow cytometric measurement of STAT5 phosphorylation in cytomegalovirus‐stimulated T cells
Bitar, Michael; Boettcher, Michael; Boldt, Andreas; Hauck, Fabian; Koehl, Ulrike; Liebert, Uwe G.; Magg, Thomas; Schulz, Marian S.; Sack, Ulrich
Journal Article
2021Induced dendritic cells co-expressing GM-CSF/IFN-α/tWT1 priming T and B cells and automated manufacturing to boost GvL
Bialek-Waldmann, Julia K.; Domning, Sabine; Esser, Ruth; Glienke, Wolfgang; Mertens, Mira; Aleksandrova, Krasimira; Arseniev, Lubomir; Kumar, Suresh; Schneider, Andreas; Koenig, Johannes; Theobald, Sebastian J.; Tsay, Hsin-Chieh; Cornelius, Angela D.A.; Bonifacius, Agnes; Eiz-Vesper, Britta; Figueiredo, Constança; Schaudien, Dirk; Talbot, Steven R.; Bleich, Andre; Spineli, Loukia M.; Kaisenberg, Constantin S. von; Clark, Caren; Blasczyk, Rainer; Heuser, Michael; Ganser, Arnold; Koehl, Ulrike; Farzaneh, Farzin; Stripecke, Renata
Journal Article
2021Low energy electron irradiation is a potent alternative to gamma irradiation for the inactivation of (CAR-)NK-92 cells in ATMP manufacturing
Walcher, Lia; Kistenmacher, Ann-Kathrin; Sommer, Charline; Böhlen, Sebastian; Ziemann, Christina; Dehmel, Susann; Tretbar, Sandy; Klöß, Stephan; Schambach, Axel; Morgan, Michael A.; Löffler, Dennis; Kämpf, Christoph; Blumert, Conny; Reiche, Kristin; Beckmann, Jana; König, Ulla; Standfest, Bastian; Thoma, Martin; Makert, Gustavo R.; Ulbert, Sebastian; Kossatz-Böhlert, Uta; Köhl, Ulrike; Dünkel, Anna; Fricke, Stephan
Journal Article
2020Biotechnologische Innovationen im Bereich zellulärer Therapien
Koehl, Ulrike; Augustin, Jens; Quaiser, Andrea; Blaudszun, André-René; Vucinic, Vladan; Platzbecker, Uwe; Aleksandrova, Krasimira; Kebbel, Kati; Schmiedeknecht, Gerno; Fricke, Stephan
Journal Article
2020CAR-NK-Zellen im Einsatz der Immunonkologie
Quaiser, Andrea; Arseniev, Lubomir; Koehl, Ulrike
Journal Article
2020Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues
Winkel, Andreas; Jaimes, Yarúa; Melzer, Catharina; Dillschneider, Philipp; Hartwig, Henning; Stiesch, Meike; Ohe, Juliane von der; Strauss, Sarah; Vogt, Peter M.; Hamm, Anika; Burmeister, Laura; Roger, Yvonne; Elger, Kristen; Floerkemeier, Thilo; Weissinger, Eva M.; Pogozhykh, Olena; Müller, Thomas; Selich, Anton; Rothe, Michael; Petri, Susanne; Koehl, Ulrike; Hass, Ralf; Hoffmann, Andrea
Journal Article
2020Editorial: Modulation of human immune parameters by anticancer therapies
Sack, Ulrich; Tárnok, Attila; Preijers, Frank; Koehl, Ulrike; Na, Il-Kang
Editorial
2020Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo
Warnecke, Athanasia; Harre, Jennifer; Staecker, Hinrich; Prenzler, Nils; Strunk, Dirk; Couillard-Despres, Sebastien; Romanelli, Pasquale; Hollerweger, Julia; Lassacher, Teresa; Auer, Daniela; Pachler, Karin; Wietzorrek, Georg; Koehl, Ulrike; Lenarz, Thomas; Schallmoser, Katharina; Laner-Plamberger, Sandra; Falk, Christine S.; Rohde, Eva; Gimona, Mario
Journal Article
2020From cancer to immune-mediated diseases and tolerance induction: Lessons learned from immune oncology and classical anti-cancer treatment
Klöß, Stephan; Dehmel, Susann; Braun, Armin; Parnham, Michael J.; Koehl, Ulrike; Schiffmann, Susanne
Journal Article
2020Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: An analysis from the European Society for Blood and Marrow Transplantation
Heilig, Christoph E.; Badoglio, Manuela; Labopin, Myriam; Fröhling, Stefan; Secondino, Simona; Heinz, Jürgen; Nicolas-Virelizier, Emanuelle; Blaise, Didier; Korenbaum, Clément; Santoro, Armando; Verbeek, Mareike; Krüger, William; Siena, Salvatore; Passweg, Jakob R.; Nicola, Massimo di; Rifón, Jose; Dreger, Peter; Koehl, Ulrike; Chabannon, Christian; Pedrazzoli, Paolo
Journal Article
2020Harnessing NK cell checkpoint-modulating immunotherapies
Chauhan, Sachin Kumar Singh; Koehl, Ulrike; Klöß, Stephan
Journal Article
2020High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia
Müller, Stephan A.; Bexte, Tobias; Gebel, Veronika; Kalensee, Franziska; Stolzenberg, Eva; Hartmann, Jessica; Koehl, Ulrike; Schambach, Axel; Wels, Winfried S.; Modlich, Ute; Ullrich, Evelyn
Journal Article
2020Management of adults and children undergoing chimeric antigen receptor T-cell therapy: Best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE)
Yakoub-Agha, Ibrahim; Chabannon, Christian; Bader, Peter; Basak, Grzegorz W.; Bönig, Halvard B.; Ciceri, Fabio; Corbacioglu, Selim; Duarte, Rafael F.; Einsele, Hermann; Hudecek, Michael; Kersten, Marie José; Koehl, Ulrike; Kuball, Jürgen H.E.; Mielke, Stephan; Mohty, Mohamad; Murray, John; Nagler, Arnon; Robinson, Stephen; Saccardi, Riccardo; Sanchez-Guijo, Fermin; Snowden, John A.; Srour, Micha; Styczynski, Jan; Urbano-Ispizua, Alvaro; Hayden, Patrick J.; Kröger, Nicolaus M.
Journal Article
2020New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions
Saidu, Nathaniel Edward Bennett; Bonini, Chiara; Dickinson, Anne M.; Grce, Magdalena; Inngjerdingen, Marit; Koehl, Ulrike; Toubert, Antoine; Zeiser, Robert; Galimberti, Sara
Journal Article
2020Nicotinamide Inhibits Self-renewal and Induces Granulocyte Differentiation of Multipotent Progenitor Cells
Nasr, Waseem; Fabian, Claire; Arnold, Katrin; Köhl, Ulrike; Sack, Ulrich; Weiss, Ronald; Cross, Michael; Hauschildt, Sunna
Journal Article
2020The role of lncRNAs TAPIR-1 and -2 as diagnostic markers and potential therapeutic targets in prostate cancer
Friedrich, Maik; Wiedemann, Karolin; Reiche, Kristin; Puppel, Sven Holger; Pfeifer, Gabriele; Zipfel, Ivonne; Binder, Stefanie; Koehl, Ulrike; Müller, Gerd A.; Engeland, Kurt; Aigner, Achim; Füssel, Susanne; Fröhner, Michael; Peitzsch, Claudia; Dubrovska, Anna; Rade, Michael; Christ, Sabina; Schreiber, Stephan; Hackermüller, Jörg; Lehmann, Jörg; Toma, Marieta I.; Muders, Michael H.; Sommer, Ulrich; Baretton, Gustavo B.; Wirth, Manfred P.; Horn, Friedemann
Journal Article
2020Tumors provoke inflammation and perineural microlesions at adjacent peripheral nerves
Cohnen, Jennifer; Kornstädt, Lisa; Hahnefeld, Lisa; Ferreiros, Nerea; Pierre, Sandra; Koehl, Ulrike; Deller, Thomas; Geisslinger, Gerd; Scholich, Klaus
Journal Article
2019CAR-expressing natural killer cells for cancer retargeting
Klöß, Stephan; Kretschmer, Anna; Stahl, Lilly; Fricke, Stephan; Koehl, Ulrike
Journal Article
2019CAR-T-Zellen: Update 2019
Dluczek, Sarah; Tretbar, Sandy; Fricke, Stephan; Koehl, Ulrike
Journal Article
2019Cellular therapeutics - living drugs. Editorial
Humpe, Andreas; Köhl, Ulrike
Editorial
2019Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering
Oberschmidt, Olaf; Morgan, Michael A.; Huppert, Volker; Kessler, Jörg; Gardlowski, Tanja; Matthies, Nadine; Aleksandrova, Krasimira; Arseniev, Lubomir; Schambach, Axel; Koehl, Ulrike; Klöß, Stephan
Journal Article
2019Ergänzung und Alternative zu CAR-T-Zellen?. CAR-NK-Zellen in der Immunonkologie
Quaiser, Andrea; Koehl, Ulrike
Internet Contribution
2019Evaluating STAT5 Phosphorylation as a Mean to Assess T Cell Proliferation
Bitar, Michael; Boldt, Andreas; Freitag, Marie-Theres; Gruhn, Bernd; Koehl, Ulrike; Sack, Ulrich
Journal Article
2019Functionality and cell senescence of CD4/CD8-selected CD20 CAR T cells manufactured using the automated CliniMACS Prodigy® platform
Aleksandrova, Krasimira; Leise, Jana; Priesner, Christoph; Melk, Anette; Kubiank, Fanni; Abken, Hinrich; Hombach, Andreas; Aktas, Murat; Essl, Mike; Bürger, Iris; Kaiser, Andrew D.; Rauser, Georg; Jurk, Marion; Goudeva, Lilia; Glienke, Wolfgang; Arseniev, Lubomir; Esser, Ruth; Koehl, Ulrike
Journal Article
2019Molekulare und zellbasierte Krebstherapie - quo vadis?
Lordick, Florian; Platzbecker, Uwe; Büch, E.; Koehl, Ulrike
Journal Article
2019Preclinical assessment of suitable natural killer cell sources for chimeric antigen receptor natural killer-based "off-the-shelf" acute myeloid leukemia immunotherapies
Klöß, Stephan; Oberschmidt, Olaf; Dahlke, Julia; Vu, Xuan-Khang; Neudörfl, Christine; Kloos, Arnold; Gardlowski, Tanja; Matthies, Nadine; Heuser, Michael; Meyer, Johann; Sauer, Martin; Falk, Christine S.; Koehl, Ulrike; Schambach, Axel; Morgan, Michael A.
Journal Article
2018CAR T Cells in trials: Recent achievements and challenges that remain in the production of modified T cells for clinical applications
Köhl, Ulrike; Arsenieva, Stanislava; Holzinger, Astrid; Abken, Hinrich
Journal Article
2018Editorial: Tailoring NK cell receptor-ligand interactions: An art in evolution
Köhl, Ulrike; Toubert, Antoine; Pittari, Gianfranco
Editorial
2018Joint modeling of immune reconstitution post haploidentical stem cell transplantation in pediatric patients with acute leukemia comparing CD34+-selected to CD3/CD19-depleted grafts in a retrospective multicenter study
Salzmann-Manrique, Emilia; Bremm, Melanie; Hünecke, Sabine; Stech, Milena; Orth, Andreas; Eyrich, Matthias; Schulz, Ansgar; Esser, Ruth; Klingebiel, Thomas; Bader, Peter; Herrmann, Eva; Köhl, Ulrike
Journal Article
2018Manufacturing mesenchymal stromal cells for the treatment of graft-versus-host disease
Trento, Cristina; Bernardo, Maria Ester; Nagler, Arnon; Kuçi, Selim; Bornhäuser, Martin; Köhl, Ulrike; Strunk, Dirk; Galleu, Antonio; Sanchez-Guijo, F.; Gaipa, Giuseppe; Introna, Martino; Bukauskas, Adomas; Blanc, Katarina le; Apperley, Jane; Roelofs, Hélène; Campenhout, Ann van; Béguin, Yves P.; Kuball, Jürgen H.E.; Lazzari, Lorenza; Avanzini, Maria Antonietta; Fibbe, Willem E.; Chabannon, Christian; Bonini, Chiara; Dazzi, Francesco
Journal Article
2018Was ist gesichert bei den Zelltherapien?
Quaiser, A.; Köhl, Ulrike
Journal Article