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| 2013 | Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices
Switalla, Simone; Knebel, Jan; Ritter, Detlef; Dasenbrock, Clemens; Krug, Norbert; Braun, Armin; Sewald, Katherina | Journal Article |
| 2012 | Acute cigarette smoke exposure induces cytotoxicity and inflammation in living tissue of precision-cut lung slices
Lauenstein, Lan; Switalla, Simone; Ritter, Detlef; Knebel, Jan; Dasenbrock, Clemens; Braun, Armin; Sewald, Katherina | Abstract, Conference Paper |
| 2012 | In vitro study revealed different size behavior of different nanoparticles
Schaudien, D.; Knebel, J.; Creutzenberg, O. | Journal Article |
| 2011 | Improvement of experimental methods for toxicological characterization of inhalable substances in vitro by in situ analysis of the cellular status based on fluorescence stainings
Ritter, Detlef; Knebel, Jan | Conference Paper, Journal Article |
| 2011 | Prävalidierungsstudie zur Prüfung der toxischen Wirkung von inhalativ wirksamen Stoffen (Gase)
Knebel, Jan; Ritter, Detlef; Berger-Preiß, Edith; Kock, Heiko; Liebsch, Manfred; Smirnova, Lena; Pirow, Ralph; Linsel, Gunter; Bauer, Mario; Graebsch, Carolin | Study |
| 2011 | Toxicological characterization of inhalable substances and aerosols in vitro: Enhancement of experimental methods by in situ fluorescence analysis of the cellular status during exposure
Ritter, Detlef; Knebel, Jan | Journal Article, Conference Paper |
| 2011 | Untersuchungen zum biologischen Effekt inhalierbarer Aerosole in vitro
Lange, Carsten
: Scharfenberg, Klaus (Erstprüfer); Dasenbrock, Clemens (Zweitprüfer); Knebel, Jan (Betreuer); Ritter, Detlef (Betreuer) | Bachelor Thesis |
| 2010 | Effects of acute in vitro exposure of murine precision-cut lung slices to gaseous nitrogen dioxide and ozone in an air-liquid interface (ALI) culture
Switalla, S.; Knebel, J.; Ritter, D.; Krug, N.; Braun, A.; Sewald, K. | Journal Article |
| 2010 | PCLS (Precision Cut Lung Slices) as a putative model for genotoxicity testing by application of the comet assay
Ritter, D.; Switalla, S.; Sewald, K.; Knebel, J. | Abstract, Conference Paper |
| 2010 | Testing of the toxicity of volatile compounds on human lung cells using the Air/Liquid Interface (ALI) culturing and exposure technique: A prevalidation study
Pirow, R.; Smirnova, L.; Liebsch, M.; Tharmann, J.; Luch, A.; Graebsch, C.; Bauer, M.; Linsel, G.; Siemers, R.; Otto, C.; Berger-Preiß, E.; Kock, H.; Oertel, A.; Ritter, D.; Knebel, J. | Journal Article, Conference Paper |
| 2009 | Anordnung zur Durchfuehrung eines Verfahrens zur Untersuchung der Wirkung eines gasfoermigen Mediums auf ein biologisches Pruefsystem unter Verwendung eines extrazellulaeren Metabolisierungssystems
Knebel, J.; Ritter, D. | Patent |
| 2009 | Cytokine production after acute exposure of precision cut lung slices to NO2 and O3
Switalla, S.; Ritter, D.; Krug, N.; Knebel, J.; Braun, A.; Sewald, K. | Abstract, Journal Article |
| 2009 | Geltraeger zur Durchfuehrung des COMET-Assays mit Automatisierungsmoeglichkeit im Roboter-gestuetzten Analysebetrieb zur Realisierung eines Hochdurchsatz-Verfahrens
Ritter, D.; Knebel, J. | Patent |
| 2009 | Genotoxicity testing in vitro - development of a higher throughput analysis method based on the comet assay
Ritter, D.; Knebel, J. | Journal Article, Conference Paper |
| 2008 | Precision cut lung slices for testing of gaseous compounds
Switalla, S.; Sewald, K.; Ritter, D.; Henjakovic, M.; Krug, N.; Knebel, J.; Braun, A. | Conference Paper, Journal Article |
| 2008 | Referenzpraeparat fuer eine Untersuchungsmethode unter Verwendung eines bildgebenden Erfassungs- und Auswertungsverfahrens
Ritter, D.; Knebel, J. | Patent |
| 2008 | Standardization of the COMET-assay
Ritter, D.; Knebel, J. | Conference Paper, Journal Article |
| 2007 | Development of a procedure for high content and higher throughput analysis of DNA-damage based on the COMET-assay
Ritter, D.; Knebel, J.; Krueger, D. | Conference Paper, Journal Article |
| 2007 | Geltraeger zur Durchfuehrung des COMET-Assays mit Automatisierungsmoeglichkeit im Roboter-gestuetzten Analysebetrieb zur Realisierung eines Hochdurchsatz-Verfahrens
Ritter, D.; Knebel, J. | Patent |
| 2007 | Verfahren zur Untersuchung der Wirkung eines gasfoermigen Mediums auf ein biologisches Pruefsystem unter Verwendung eines extrazellulaeren Metabolisierungssystems sowie Vorrichtung zur Durchfuehrung des Verfahrens
Knebel, J.; Ritter, D. | Patent |
| 2004 | Comparative assessment of toxicities of mainstream smoke from commercial cigarettes
Ritter, D.; Knebel, J.W.; Aufderheide, M. | Journal Article |
| 2003 | Exposure of human lung cells to inhalable substances
Ritter, D.; Knebel, J.W.; Aufderheide, M. | Journal Article |
| 2003 | An improved in vitro model for testing the pulmonary toxicity of complex mixtures such as cigarette smoke
Aufderheide, M.; Knebel, J.W.; Ritter, D. | Journal Article |
| 2003 | Novel approaches for studying pulmonary toxicity in vitro
Aufderheide, M.; Knebel, J.W.; Ritter, D. | Journal Article |
| 2002 | Direct exposure of human lung cells to native cigarette mainstream smoke
Ritter, D.; Knebel, J.; Aufderheide, M. | Conference Paper |
| 2002 | Exposure of human lung cells to native diesel motor exhaust - development of an optimized in vitro test strategy
Knebel, J.W.; Ritter, D.; Aufderheide, M. | Journal Article |
| 2002 | A method for the in vitro exposure of human cells to environmental and complex gaseous mixtures
Aufderheide, M.; Knebel, J.W.; Ritter, D. | Journal Article |
| 2002 | A new system for the direct in vitro exposure of human lung cells to native cigarette mainstream smoke
Ritter, D.; Knebel, J.W.; Aufderheide, M. | Conference Paper |
| 2001 | Development and validation of a semiautomatic system for generation and deposition of sprays on isolated cells of the respiratory tract
Knebel, J.W.; Ritter, D.; Hoffmann, K.; Lödding, H.; Windt, H.; Koch, W.; Aufderheide, M. | Journal Article |
| 2001 | In vitro efficacy of chemotherapeutics as determined by 50 % inhibitory concentrations in cell cultures of mammary gland tumors obtained from dogs
Simon, D.; Knebel, J.W.; Baumgärtner, W.; Aufderheide, M.; Meyer-Lindenberg, A.; Nolte, I. | Journal Article |
| 2001 | In vitro exposure of isolated cells to native gaseous compounds - development and validation of an optimized system for human lung cells
Ritter, D.; Knebel, J.W.; Aufderheide, M. | Journal Article |
| 2001 | A method for in vitro analysis of the biological activity of complex mixtures such as sidestream cigarette smoke
Aufderheide, M.; Ritter, D.; Knebel, J.W.; Scherer, G. | Journal Article |
| 2001 | Use of cultivated osteoprogenitor cells to increase bone formation in segmental mandibular defects: An experimental pilot study in sheep
Schliephake, H.; Knebel, J.W.; Aufderheide, M.; Tauscher, M. | Journal Article |
| 1999 | Development of a cell culture model system for routine testing of substances inducing oxidative stress
Ritter, D.; Knebel, J.W.; Aufderheide, M.; Mohr, U. | Journal Article |
| 1998 | Development of an in vitro system for studying effects of native and photochemically transformed gaseous compounds using an air/liquid culture technique
Knebel, J.W.; Ritter, D.; Aufderheide, M. | Journal Article |
| 1998 | Experimental chemotherapy of human squamous cell carcinoma heterotransplanted to nude mice
Huttmann, C.; Fokas, K.; Eckardt, A.; Kuske, M.; Knebel, J.W.; Hedrich, H.-J.; Haindl, J. | Journal Article |
| 1998 | Experimental reconstruction of the mandible using polyactic acid tubes and basic fibroblast growth factor in alloplastic scaffolds
Schliephake, H.; Jamil, M.U.; Knebel, J.W. | Journal Article |
| 1998 | Micronucleus induction in V79 cells after direct exposure to whole cigarette smoke
Massey, E.; Aufderheide, M.; Koch, W.; Lodding, H.; Pohlmann, G.; Windt, H.; Jarck, P.; Knebel, J.W. | Journal Article |
| 1997 | Development of a cell culture system for studying effects of native and photochemically transformed gaseous compounds using an air/liquid culture technique
Ritter, D.; Knebel, J.W.; Aufderheide, M.; Palm, W.-U.; Zetzsch, C. | Conference Paper |
| 1996 | Continuous cell lines derived from head and neck tumors for mechanistic studies in vitro in a nude mouse animal model
Knebel, J.W.; Eckardt, A.; Fokas, K.; Aufderheide, M.; Nolte, M. | Conference Paper |
| 1996 | PAH metabolism in cultured mammalian lung epithelial cells
Emura, M.; Jacob, J.; Grimmer, G.; Knebel, J.W.; Raab, G.; Mohr, U. | Journal Article |
| 1996 | Requirement of monooxygenase induction in cultured lung epithelial cells for metabolism of PAH
Jacob, J.; Emura, M.; Grimmer, G.; Knebel, J.W.; Raab, G.; Mohr, U. | Journal Article |
| 1994 | Comparison of biological effects of different polycyclic aromatic hydrocarbons in lung cells of hamster and rat in vitro
Knebel, J.W.; Aufderheide, M.; Emura, M. | Journal Article |