Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Association of human FOS promoter variants with the occurrence of knee-osteoarthritis in a case control association study
Huber, René; Kirsten, Holger; Näkki, Annu; Pohlers, Dirk; Thude, Hansjörg; Eidner, Thorsten; Heinig, Matthias; Brand, Korbinian; Ahnert, Peter; Kinne, Raimund W.
Journal Article
2019Post-mortem in situ stability of serum markers of cerebral damage and acute phase response
Ondruschka, B.; Woydt, L.; Bernhard, M.; Franke, H.; Kirsten, H.; Löffler, S.; Pohlers, D.; Hammer, N.; Dreßler, J.
Journal Article
2018Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1
Müller, Bent; Boltze, Johannes; Czepezauer, Ivonne; Hesse, Volker; Wilcke, Arndt; Kirsten, Holger
Journal Article
2018Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis
Kirsten, Holger; Rosendahl, Jonas; Seltsam, Katharina; Zimmer, Constantin; Beer, Sebastian; Masson, Emmanuelle; Chen, Jian-Min; Ruffert, Claudia; Lichtner, Peter K.; Laumen, Helmut; Weiss, Frank Ulrich; Kovacs, Peter; Hegyi, Eszter; Algül, Hana; Bühler, Florence; Bruno, Marco J.; Bugert, Peter; Burkhardt, R.; Cavestro, Giulia Martina; Cichoż-Lach, Halina; Farré, Antoni; Frank, Josef; Gambaro, Giovanni; Gimpfl, Sebastian; Grallert, Harald; Griesmann, Heidi; Grützmann, Robert; Hellerbrand, Claus; Hegyi, Péter P.; Hollenbach, Marcus; Iordache, Sevastitia; Jurkowska, Graźyna E.; Keim, Volker; Kiefer, Falk; Krug, Sebastian; Landt, Olfert; Leo, Milena Di; Lerch, Markus M.; Lévy, Philippe L.; Loeffler, Markus; Löhr, Matthias Matthias; Ludwig, Maren; Macek, Milan; Malats, Núria; Małecka-Panas, Ewa I.A.; Malerba, Giovanni; Mann, Karl H.; Mayerle, Julia V.; Mohr, Sonja; Te Morsche, René H.M.; Motyka, Marie; Mueller, Sebastian; Müller, Thomas F.; Nöthen, Markus M.; Pedrazzoli, Sergio; Pereira, Stephen
Journal Article
2018Human brain arousal in the resting state: A genome-wide association study
Jawinski, P.; Kirsten, H.; Sander, C.; Spada, J.; Ulke, C.; Huang, J.; Burkhardt, R.; Scholz, M.; Hensch, T.; Hegerl, U.
Journal Article
2018Intra-individual alterations of serum markers routinely used in forensic pathology depending on increasing post-mortem interval
Woydt, L.; Bernhard, M.; Kirsten, H.; Burkhardt, R.; Hammer, N.; Gries, A.; Dreßler, J.; Ondruschka, B.
Journal Article
2017Alteration of multiple leukocyte gene expression networks is linked with magnetic resonance markers of prognosis after acute ST-Elevation myocardial infarction
Teren, Andrej; Kirsten, Holger; Beutner, F.; Scholz, M.; Holdt, L.M.; Teupser, D.; Gutberlet, M.; Thiery, J.; Schuler, G.; Eitel, I.
Journal Article
2017ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR
Müller, Bent; Schaadt, Gesa; Boltze, Johannes; Emmrich, Frank; Skeide, Michael A.; Neef, Nicole; Kraft, Indra; Brauer, Jens; Friederici, Angela D.; Kirsten, Holger; Wilcke, Arndt
Journal Article
2017Dyslexia risk gene relates to representation of sound in the auditory brainstem
Neel, Nicole E.; Müller, Bent; Liebig, Johanna; Schaadt, Gesa; Grigutsch, Maren; Gunter, Thomas C.; Wilcke, Arndt; Kirsten, Holger; Skeide, Michael A.; Kraft, Indra; Kraus, Nina; Emmrich, Frank; Brauer, Jens; Boltze, Johannes; Friederici, Angela D.
Journal Article
2017Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood
Lukowski, S.W.; Lloyd-Jones, L.R.; Holloway, A.; Kirsten, H.; Hemani, G.; Yang, J.; Small, K.; Zhao, J.; Metspalu, A.; Dermitzakis, E.T.; Gibson, G.; Spector, T.D.; Thiery, J.; Scholz, M.; Montgomery, G.W.; Esko, T.; Visscher, P.M.; Powell, J.E.
Journal Article
2017Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery
Pott, J.; Burkhardt, R.; Beutner, F.; Horn, K.; Teren, A.; Kirsten, H.; Holdt, L.M.; Schuler, G.; Teupser, D.; Loeffler, M.; Thiery, J.; Scholz, M.
Journal Article
2016Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort
Müller, Bent; Wilcke, Arndt; Czepezauer, Ivonne; Ahnert, Peter; Boltze, Johannes; Kirsten, Holger; Friederici, Angela D.; Emmrich, Frank; Brauer, Jens; Neef, Nicole; Skeide, Michael A.; Schaadt, Gesa; Kraft, Indra; Dörr, Liane
Journal Article
2016Comparing performance of modern genotype imputation methods in different ethnicities
Roshyara, Nab Raj; Horn, Katrin; Kirsten, Holger; Ahnert, Peter; Scholz, Markus
Journal Article
2016High acceptance of an early dyslexia screening test involving genetic analyses in Germany
Wilcke, Arndt; Müller, Bent; Schaadt, Gesa; Friederici, Angela D.; Emmrich, Frank; Brauer, Jens; Neef, Nicole; Skeide, Michael A.; Kraft, Indra; Czepezauer, Ivonne; Bobovnikov, Nadin; Kirsten, Holger; Boltze, Johannes
Journal Article
2016Improved prediction of complex diseases by common genetic markers
Müller, Bent; Wilcke, Arndt; Boulesteix, Anne-Laure; Brauer, Jens; Passarge, Eberhard; Boltze, Johannes; Kirsten, Holger
Journal Article
2016NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school
Skeide, Michael A.; Kraft, Indra; Müller, Bent; Schaadt, Gesa; Neef, Nicole E.; Brauer, Jens; Wilcke, Arndt; Kirsten, Holger; Boltze, Johannes; Friederici, Angela D.
Journal Article
2016Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI
Kraft, Indra; Schreiber, Jan; Cafiero, Riccardo; Metere, Riccardo; Schaadt, Gesa; Brauer, Jens; Neef, Nicole E.; Müller, Bent; Kirsten, Holger; Boltze, Johannes; Friederici, Angela D.; Skeide, Michael A.
Journal Article
2016Verfahren zur genbasierten Diagnose eines Legasthenierisikos
Wilcke, Arndt; Ahnert, Peter; Kirsten, Holger; Ligges, Carolin; Boltze, Johannes
Patent
2015Autologous bone marrow mononuclear cell therapy of ischemic stroke in sheep
Boltze, J.; Dreyer, A.; Zeisig, V.; Lobsien, D.; Gille, U.; Wagner, D.C.; Kirsten, H.; Barthel, H.
Abstract
2015Complexin2 modulates working memory-related neural activity in patients with schizophrenia
Hass, Johanna; Walton, Esther; Kirsten, Holger; Turner, Jessica; Wolthusen, Rick; Roessner, Veit; Sponheim, Scott R.; Holt, Daphne; Gollub, Randy; Calhoun, Vince; Ehrlich, Stefan
Journal Article
2015Cortical differences in preliterate children at familiar risk of dyslexia are similar to those observed in dyslexic readers
Kraft, Indra; Cafiero, Riccardo; Schaadt, Gesa; Brauer, Jens; Neef, Nicole; Müller, Bent; Kirsten, Holger; Wilcke, Arndt; Boltze, Johannes; Friederici, Angela D.; Skeide, Michael A.
Journal Article
2015Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci
Kirsten, Holger; Al-Hasani, Hoor; Holdt, Lesca M.; Gross, Arndt; Beutner, Frank; Krohn, Knut; Horn, Katrin; Ahnert, Peter; Burkhardt, Ralph; Reiche, Kristin; Hackermüller, Jörg; Löffler, Marcus; Teupser, Daniel; Thiery, Joachim; Scholz, Markus
Journal Article
2015Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children
Skeide, Michael A.; Kirsten, Holger; Kraft, Indra; Schaadt, Gesa; Müller, Bent; Neef, Nicole; Brauer, Jens; Wilcke, Arndt; Emmrich, Frank; Boltze, Johannes; Friederici, Angela D.
Journal Article
2015Integration of genome-wide SNP data and gene-expression profiles reveals six novel loci and regulatory mechanisms for amino acids and acylcarnitines in whole blood
Burckhardt, Ralph; Kirsten, Holger; Beutner, Frank; Holdt, Lesca M.; Gross, Arnd; Teren, Andrej; Tönjes, Anke; Becker, Susen; Krohn, Knut; Kovacs, Peter; Stumvoll, Michael; Teupser, Daniel; Thiery, Joachim; Ceglarek, Uta; Scholz, Markus
Journal Article
2015A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis
Fjeld, Karianne; Weiss, Frank Ulrich; Lasher, Denise; Rosendahl, Jonas; Chen, Jian-Min; Johansson, Bente B.; Kirsten, Holger; Ruffert, Claudia; Masson, Emmanuelle; Steine, Solrun J.; Bugert, Peter; Cnop, Miriam; Grützmann, Robert; Mayerle, Julia; Mössner, Joachim; Ringdal, Monika; Schulz, Hans-Ulrich; Sendler, Matthias; Simon, Peter; Sztromwasser, Pawel; Torsvik, Janniche; Scholz, Markus; Tjora, Erling; Férec, Claude; Witt, Heiko; Lerch, Markus M.; Njølstad, Pal R.; Johansson, Stefan; Molven, Anders
Journal Article
2015A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes
Nitzsche, Björn; Frey, Stephen; Collins, Louis D.; Seeger, Johannes; Lobsien, Donald; Dreyer, Antje; Kirsten, Holger; Stoffel, Michael H.; Fonov, Vladimir S.; Boltze, Johannes
Journal Article
2015Three gangliogliomas: Results of GTG-banding, SKY, genome-wide high resolution SNP-array, gene expression and review of the literature
Xu, Li-Xin; Holland, Heidrun; Kirsten, Holger; Ahnert, Peter; Krupp, Wolfgang; Bauer, Manfred; Schober, Ralf; Mueller, Wolf; Fritzsch, Dominik; Meixensberger, Jürgen; Koschny, Ronald
Journal Article
2015Working-memory endophenotype and dyslexia-associated genetic variant predict dyslexia phenotype
Männel, Claudia; Meyer, Lars; Wilcke, Arndt; Boltze, Johannes; Kirsten, Holger; Friederici, Angela D.
Journal Article
2014Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression
Burkhardt, Jana; Blume, Mechthild; Petit-Teixeira, Elisabeth; Teixeira, Vitor Hugo; Steiner, Anke; Quente, Elfi; Wolfram, Grit; Scholz, Markus; Pierlot, Céline; Migliorini, Paola; Bombardieri, Stefano; Balsa, Alejandro; Westhovens, René; Barrera, Pilar; Radstake, Timothy R.D.J.; Alves, Helena; Bardin, Thomas; Prum, Bernard; Emmrich, Frank; Cornelis, Francois; Ahnert, Peter; Kirsten, Holger
Journal Article
2014Genetic risk variants for dyslexia on chromosome 18 in a german cohort
Müller, Bent; Ahnert, Peter; Burkhardt, Jana; Brauer, J.; Czepezauer, Ivonne; Quente, Elfi; Boltze, Johannes; Wilcke, Arndt; Kirsten, Holger
Journal Article
2014Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin
Tönjes, Anke; Scholz, Markus; Breitfeld, Jana; Marzi, Carola; Grallert, Harald; Gross, Arnd; Ladenvall, Claes; Schleinitz, Dorit; Krause, Kerstin; Kirsten, Holger; Laurila, Esa; Kriebel, Jennifer; Thorand, Barbara; Rathmann, Wolfgang; Groop, Leif; Prokopenko, Inga; Isomaa, Bo; Beutner, Frank; Kratzsch, Jürgen; Thiery, Joachim; Fasshauer, Mathias; Klöting, Nora; Gieger, Christian; Blüher, Matthias; Stumvoll, Michael; Kovacs, Peter
Journal Article
2014Impact of pre-imputation SNP-filtering on genotype imputation results
Roshyara, Nab Raj; Kirsten, Holger; Horn, Katrin; Ahnert, Peter; Scholz, Markus
Journal Article
2013Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma
Holland, Heidrun; Xu, Li-Xin; Ahnert, Peter; Kirsten, Holger; Koschny, Ronald; Bauer, Manfred; Schober, Ralf; Meixensberger, Jürgen; Krupp, Wolfgang
Journal Article
2013A genome-wide association study suggests novel loci associated with a Schizophrenia-related brain-based phenotype
Hass, Johanna; Walton, Esther; Kirsten, Holger; Liu, Jingyu; Priebe, Lutz; Wolf, Christiane; Karbalai, Nazanin; Gollub, Randy; White, Tonya; Roessner, Veit; Müller, Kathrin U.; Paus, Tomas; Smolka, Michael N.; Schumann, Gunter; Scholz, Markus; Cichon, Sven; Calhoun, Vince; Ehrlich, Stefan
Journal Article
2012Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort
Burkhardt, Jana; Kirsten, Holger; Holland, Heidrun; Krupp, Wolfgang; Ligges, Carolin; Quente, Elfi; Boltze, Johannes; Ahnert, Peter; Wilcke, Arndt
Journal Article
2012Association study of a functional genetic variant in KIAA0319 in German dyslexics
Kirsten, Holger; Wilcke, Arndt; Ligges, Carolin; Boltze, Johannes; Ahnert, Peter
Journal Article
2012Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locus-specific FISH, and high density SNP-array
Holland, Heidrun; Ahnert, Peter; Koschny, Ronald; Kirsten, Holger; Bauer, Manfred; Schober, Ralf; Meixensberger, Jürgen; Fritzsch, Dominik; Krupp, Wolfgang
Journal Article
2012Differential allelic expression of IL13 and CSF2 genes associated with asthma
Burkhardt, J.; Kirsten, H.; Wolfram, G.; Quente, E.; Ahnert, P.
Journal Article
2011High resolution genomic profiling and classical cytogenetics in a group of benign and atypical meningiomas
Holland, H.; Mocker, K.; Ahnert, P.; Kirsten, H.; Hantmann, H.; Koschny, R.; Bauer, M.; Schober, R.; Scholz, M.; Meixensberger, J.; Krupp, W.
Journal Article
2011Imaging genetics of FOXP2 in dyslexia
Wilcke, A.; Ligges, C.; Burkhardt, J.; Alexander, M.; Wolf, C.; Quente, E.; Ahnert, P.; Hoffmann, P.; Becker, A.; Müller-Myhsok, B.; Cichon, S.; Boltze, J.; Kirsten, H.
Journal Article
2011Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis
Holland, H.; Livrea, M.; Ahnert, P.; Koschny, R.; Kirsten, H.; Meixensberger, J.; Bauer, M.; Schober, R.; Fritzsch, D.; Krupp, W.
Journal Article
2011Multiple meningioma with different grades of malignancy: Case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics
Mocker, K.; Holland, H.; Ahnert, P.; Schober, R.; Bauer, M.; Kirsten, H.; Koschny, R.; Meixensberger, J.; Krupp, W.
Journal Article
2011Towards a genetic screening test for dyslexia allowing functional regeneration
Kirsten, H.; Wilcke, A.; Burkhardt, J.; Quente, E.; Ligges, C.; Scholz, M.; Klopp, N.; Illig, T.; Mielck, A.; Ahnert, P.; Boltze, J.
Conference Paper
2010Differential allelic expression of genes associated with asthma
Burkhardt, J.; Kirsten, H.; Wolfram, G.; Quente, E.; Ahnert, P.
Abstract
2010Imaging genetics of FOXP2 in dyslexia
Ahnert, P.; Boltze, J.; Ligges, C.; Kirsten, H.; Wilcke, A.; Burkhardt, J.; Quente, E.
Abstract
20095HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population
Kirsten, Holger; Burkhardt, Jana; Hantmann, Helene; Hunzelmann, Nico; Vaith, Peter; Ahnert, Peter; Melchers, Inga
Journal Article
2009Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study
Kirsten, Holger; Petit-Teixeira, Elisabeth; Scholz, Markus; Hasenclever, Dirk; Hantmann, Helene; Heider, Dirk; Wagner, Ulf; Sack, Ulrich; Teixeira, Victor Hugo; Prum, Bernard; Burkhardt, Jana; Pierlot, Céline; Emmrich, Frank; Cornelis, Francois; Ahnert, Peter
Journal Article
2009Association of the x-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis
Burkhardt, J.; Petit-Teixeira, E.; Teixeira, V.H.; Kirsten, H.; Garnier, S.; Ruehle, S.; Oeser, C.; Wolfram, G.; Scholz, M.; Migliorini, P.; Balsa, A.; Westhovens, R.; Barrera, P.; Alves, H.; Pascual-Salcedo, D.; Bombardieri, S.; Dequeker, J.; Radstake, T.R.; Riel, P. van; Putte, L. van de; Bardin, T.; Prum, B.; Buchegger-Podbielski, U.; Emmrich, F.; Melchers, I.; Cornelis, F.; Ahnert, P.
Journal Article
2009A family-based study does not support the association of a functional polymorphism in the gene for endothelial nitric oxide synthase with risk for rheumatoid arthritis
Kirsten, H.; Petit-Teixeira, E.; Hantmann, H.; Reichardt, J.; Burkhardt, J.; Emmrich, F.; Cornelis, F.; Ahnert, P.
Journal Article
2009Genetic basics of dyslexia - recent research
Wilcke, A.; Kirsten, H.
Abstract
2009The role of gene DCDC2 in German dyslexics
Wilcke, Arndt; Weissfuss, J.; Kirsten, H.; Wolfram, G.; Boltze, Johannes; Ahnert, P.; Kirsten, H.
Journal Article
2007Cytogenetic and molecular biological characterization of an adult medulloblastoma
Holland, H.; Koschny, R.; Krupp, W.; Meixensberger, J.; Bauer, M.; Schober, R.; Kirsten, H.; Ganten, T.M.; Ahnert, P.
Journal Article
2006CalcDalton: a tool for multiplex genotyping primer design for single-base extension reactions using cleavable primers
Kirsten, H.; Dienst, S.; Emmrich, F.; Ahnert, P.
Journal Article