Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2018Assessment of the cytotoxic and immunomodulatory effects of substances in human precision-cut lung slices
Neuhaus, Vanessa; Danov, Olga; Konzok, Sebastian; Obernolte, Helena; Dehmel, Susann; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Zardo, Patrick; Warnecke, Gregor; Martin, Christian; Braun, Armin; Sewald, Katherina
Journal Article
2018Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Ackermann, Mania; Kempf, Henning; Hetzel, Miriam; Hesse, Christina; Hashtchin, Anna Rafiei; Brinkert, Kerstin; Schott, Juliane Wilhelmine; Haake, Kathrin; Kühnel, Mark Philipp; Glage, Silke; Figueiredo, Constanca; Jonigk, Danny; Sewald, Katherina; Schambach, Axel; Wronski, Sabine; Moritz, Thomas; Martin, Ulrich; Zweigerdt, Robert; Munder, Antje; Lachmann, Nico
Journal Article
2018Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs
Danov, Olga; Jiménez Delgado, Sharon Melissa; Obernolte, Helena; Seehase, Sophie; Dehmel, Susann; Braubach, Peter; Fieguth, Hans-Gerd; Matschiner, Gabriele; Fitzgerald, Mary; Jonigk, Danny; Knauf, Sascha; Pfennig, Olaf; Warnecke, Gregor; Wichmann, Judy; Braun, Armin; Sewald, Katherina
Journal Article
2018Impaired IFNγ-signaling and mycobacterial clearance in IFNγR1-deficient human iPSC-derived macrophages
Neehus, Anna-Lena; Lam, Jenny; Haake, Kathrin; Merkert, Sylvia; Schmidt, Nico; Mucci, Adele; Ackermann, Mania; Schubert, Madline; Happle, Christine; Kühnel, Mark Philipp; Blank, Patrick; Philipp, Friederike; Goethe, Ralph; Jonigk, Danny; Martin, Ulrich; Kalinke, Ulrich; Baumann, Ulrich; Schambach, Axel; Roesler, Joachim; Lachmann, Nico
Journal Article
2015Cigarette smoke and cigarette smoke condensate exposure induces cytotoxicity and inflammation in precision-cut lung slices
Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan; Braubach, Peter; Jonigk, Danny; Fieguth, Hans-Gerd; Braun, Armin; Sewald, Katherina
Abstract
2015Cigarette smoke and cigarette smoke condensate induce cell injury and early biomarkers of inflammation in human and rodent Precision-Cut Lung Slices
Obernolte, Helena; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina
Abstract
2015Cigarette smoke condensate and cigarette smoke induce cytotoxicity and inflammation in human and rodent Precision-Cut Lung Slices of different species
Obernolte, Helena; Konzok, Sebastian; Ritter, Detlef; Knebel, Jan W.; Braubach, Peter; Jonigk, Danny; Braun, Armin; Sewald, Katherina
Abstract
2015Development of a human organotypic tumor invasion model of cancer cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS)
Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina
Abstract
2015Induced cytotoxicity revealed species diversity of rat and human lung tissue by repeated chemical exposure
Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Braubach, Peter; Jonigk, Danny; Warnecke, Gregor; Braun, Armin; Sewald, Katherina
Abstract
2015A novel human organotypic tumor invasion model of cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS) to reduce animal experiments in preclinical oncology
Konzok, Sebastian; Schindler, Susann; Jonigk, Danny; Braubach, Peter; Braun, Armin; Sewald, Katherina
Abstract
2015Species comparison of rat and human precision-cut lung slices as an alternative in risk assessment based on read-across approach
Danov, Olga; Escher, Sylvia E.; Schröder, Katrin; Vorgrimmler, David; Bersch, Claus; Braubach, Peter; Jonigk, Danny; Pfennig, Olaf; Warnecke, Gregor; Braun, Armin; Sewald, Katherina
Abstract
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Journal Article
2015Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
Knippenberg, Sarah; Ueberberg, Bianca; Maus, Regina; Bohling, Jennifer; Ding, Nadine; Tort Tarres, Meritxell; Hoymann, Heinz-G.; Jonigk, Danny; Izykowski, Nicole; Paton, James C.; Ogunniyi, Abiodun D.; Lindig, Sandro; Bauer, Michael; Welte, Tobias; Seeger, Werner; Guenther, Andreas; Sisson, H. Thomas; Gauldie, Jack; Kolb, Martin; Maus, Ulrich A.
Abstract
2013Anti-inflammatory and immunomodulatory properties of alpha1-antitrypsin without inhibition of elastase
Jonigk, Danny; Al-Omari, Mariam; Maegel, Lavinia; Müller, Meike; Izykowski, Nicole; Hong, Jaewoo; Hong, Kwangwon; Kim, Soo-Hyun; Dorsch, Martina; Mahadeva, Riva; Laenger, Florian; Kreipe, Hans; Braun, Armin; Shahaf, Galit; Lewis, Eli C.; Welte, Tobias; Dinarello, Charles A.; Janciauskiene, Sabina
Journal Article
2013Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique
Neuhaus, Vanessa; Schwarz, Katharina; Klee, Anna; Seehase, Sophie; Förster, Christine; Pfennig, Olaf; Jonigk, Danny; Fieguth, Hans-Gerd; Koch, Wolfgang; Warnecke, Gregor; Yusibov, Vidadi; Sewald, Katherina; Braun, Armin
Journal Article
2012Bacterial infection triggers exacerbation of established pulmonary fibrosis in mice: Impact on lung protective immunity
Ueberberg, Bianca; Janze, Ann-Kathrin; Steinwede, Kathrin; Maus, Regina; Magel, Lavinia; Hoymann, Heinz-Gerd; Braun, Armin; Langer, Florian; Jonigk, Danny; Kolb, Martin; Gauldie, Jack; Welte, Tobias; Maus, Ulrich A.
Abstract