Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs
Dreis, C.; Ottenlinger, F.M.; Putyrski, M.; Ernst, A.; Huhn, M.; Schmidt, K.G.; Pfeilschifter, J.M.; Radeke, H.H.
Journal Article
2018Antennenmessplatz
Curran, Brian; Großer, Volker; Huhn, Max; Lang, Klaus-Dieter; Ndip, Ivan
Patent
2018Double-wired bond wire antennas
Ndip, I.; Huhn, M.; Le, T.H.; Lang, K.-D.
Conference Paper
2017Development of a multi-project fan-out wafer level packaging platform
Braun, T.; Raatz, S.; Maass, U.; Dijk, M. van; Walter, H.; Hölck, O.; Becker, K.-F.; Töpper, M.; Aschenbrenner, R.; Wöhrmann, M.; Voges, S.; Huhn, M.; Lang, K.-D.; Wietstruck, M.; Scholz, R.F.; Mai, A.; Kaynak, M.
Conference Paper
2017Experimental verification and analysis of analytical model of the shape of bond wire antennas
Ndip, I.; Huhn, M.; Brandenburger, F.; Ehrhardt, C.; Schneider-Ramelow, M.; Reichl, H.; Lang, K.D.; Henke, H.
Journal Article
2016Broadband dielectric material characterization of epoxy molding compound
Huhn, M.; Tschoban, C.; Pötter, H.; Ndip, I.; Braun, T.; Lang, K.-D.
Conference Paper
2016Opportunities of fan-out wafer level packaging (FOWLP) for RF applications
Braun, T.; Töpper, M.; Becker, K.-F.; Wilke, M.; Huhn, M.; Maass, U.; Ndip, I.; Aschenbrenner, R.; Lang, K.-D.
Conference Paper
2016RF-MEMS for 5G mobile communications: A basic attenuator module demonstrated up to 50 GHz
Iannacci, J.; Tschoban, C.; Reyes, J.; Maaß, U.; Huhn, M.; Ndip, I.; Pötter, H.
Conference Paper
2016RF-MEMS Technology for 5G: Series and Shunt Attenuator Modules Demonstrated up to 110 GHz
Iannacci, J.; Huhn, M.; Tschoban, C.; Pötter, H.
Journal Article
2016RF-MEMS technology for future mobile and high-frequency applications: Reconfigurable 8-Bit power attenuator tested up to 110 GHz
Iannacci, J.; Huhn, M.; Tschoban, C.; Pötter, H.
Journal Article
2015Material and process trends for moving from FOWLP to FOPLP
Braun, Tanja; Voges, S.; Töpper, Michael; Wilke, Martin; Wöhrmann, M.; Maaß, Uwe; Huhn, Max; Becker, Karl-Friedrich; Raatz, Stefan; Kim, J.-U.; Aschenbrenner, Rolf; Lang, Klaus-Dieter; O'Connor, C.; Barr, R.; Calvert, J.; Gallagher, M.; Iagodkine, E.; Aoude, T.; Politis, A.
Conference Paper
2015Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies
Hristodorov, D.; Mladenov, R.; Felbert, V. von; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2014CeMoSS - certification and model-driven development of safe and secure software
Huhn, M.; Gerken, S.; Rudolph, C.
Conference Paper
2014EpCAM-Selective Elimination of Carcinoma Cells by a Novel MAP-Based Cytolytic Fusion Protein
Hristodorov, D.; Amoury, M.; Mladenov, R.; Niesen, J.; Arens, K.; Berges, N.; Hein, L.; Fiore, S. di; Pham, A.T.; Huhn, M.; Helfrich, W.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2014Human microtubule-associated protein tau mediates targeted killing of CD30+ lymphoma cells in vitro and inhibits tumour growth in vivo
Hristodorov, D.; Nordlohne, J.; Mladenov, R.; Huhn, M.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2014Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins
Schiffer, S.; Rosinke, R.; Jost, E.; Hehmann-Titt, G.; Huhn, M.; Melmer, G.; Barth, S.; Thepen, T.
Journal Article
2013Efficacy of an adapted granzyme B-based anti-CD30 cytolytic fusion protein against PI-9-positive classical Hodgkin lymphoma cells in a murine model
Schiffer, S.; Hansen, H.P.; Hehmann-Titt, G.; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2013Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells
Schiffer, S.; Letzian, S.; Jost, E.; Mladenov, R.; Hristodorov, D.; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2013Macrophage-targeted therapy of chronic wounds
Hristodorov, D.; Mladenov, R.; Aslanian, E.; Huhn, M.; Barth, S.; Thepen, T.
Book Article
2013Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo
Hristodorov, D.; Mladenov, R.; Pardo, A.; Pham, A.-T.; Huhn, M.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2013Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages
Schiffer, S.; Hristodorov, D.; Mladenov, R.; Aslanian, E.; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2013ZeMoSS-Workshop: Zertifizierung und modellgetriebene Entwicklung sicherer Software
Huhn, M.; Gerken, S.; Rudolph, C.
Conference Paper
2012Labeling of anti-MUC-1 binding single chain fv fragments to surface modified upconversion nanoparticles for an initial in vivo molecular imaging proof of principle approach
Hischemöller, A.; Walter, C.; Weiler, V.; Hummel, H.; Thepen, T.; Huhn, M.; Barth, S.; Hoheisel, W.; Köhler, K.; Dimova-Landen, D.; Bremer, C.; Haase, M.; Waldeck, J.
Journal Article
2012Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases. Review
Hristodorov, D.; Mladenov, R.; Huhn, M.; Barth, S.; Thepen, T.
Journal Article
2011In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA in a human acute myeloid leukemia xenograft tumor model
Tur, M.K.; Huhn, M.; Jost, E.; Thepen, T.; Brümmendorf, T.H.; Barth, S.
Journal Article
2010A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model
Gattenlöhner, S.; Jörißen, H.; Huhn, M.; Vincent, A.; Beeson, D.; Tzartos, S.; Mamalaki, A.; Etschmann, B.; Muller-Hermelink, H.K.; Koscielniak, E.; Barth, S.; Marx, A.
Journal Article
2010Recombinant, ETA'-based CD64 immunotoxins: Improved efficacy by increased valency, both in vitro and in vivo in a chronic cutaneous inflammation model in human CD64 transgenic mice
Ribbert, T.; Thepen, T.; Tur, M.K.; Fischer, R.; Huhn, M.; Barth, S.
Journal Article
2009Fc gamma receptor 1 (CD64), a target beyond cancer
Thepen, T.; Huhn, M.; Melmer, G.; Tur, M.K.; Barth, S.
Journal Article
2006In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen
Wicklein, D.; Stöcker, M.; Klockenbring, T.; Huhn, M.; Wodrich, M.; Haas, H.; Becker, W.-M.; Barth, S.; Petersen, A.
Journal Article
2005Antigen-specific targeting and elimination of EBV-transformed B cells by allergen toxins
Stöcker, M.; Klockenbring, T.; Huhn, M.; Nachreiner, T.; Wicklein, D.; Petersen, A.; Bauer, R.; Goerlich, R.; Fischer, R.; Barth, S.
Journal Article
2005Generation of human antibody fragments against Streptococcus mutans using a phage display chain shuffling approach
Küpper, M.B.; Huhn, M.; Spiegel, H.; Ma, J.K.-C.; Barth, S.; Fischer, R.; Finnern, R.
Journal Article
2005Recombinant anti-EGFR immunotoxin 425(scFv)-ETA' demonstrates anti-tumor activity against disseminated human pancreatic cancer in nude mice
Bruell, D.; Bruns, C.J.; Yezhelyev, M.; Huhn, M.; Müller, J.; Ischenko, I.; Decken, V. von der; Fischer, R.; Finnern, R.; Jauch, K.W.; Barth, S.
Journal Article
2004Antigen-specific targeting and elimination of EBV-transformed B cells by allergen-toxins
Klockenbring, T.; Stöcker, M.; Huhn, M.; Petersen, A.; Bauer, R.; Goerlich, R.; Fischer, R.; Barth, S.
Conference Paper
2004Auflösung chronischer Entzündungen durch Bändigung abtrünniger Makrophagen
Thepen, T.; Huhn, M.; Barth, S.
Journal Article
2004Construction of phage display libraries from reactive lymph nodes of breast carcinoma patients and selection for specifically binding human single chain Fv on cell lines
Rothe, A.; Klimka, A.; Tur, M.K.; Pfitzner, T.; Huhn, M.; Sasse, S.; Mallmann, P.; Engert, A.; Barth, S.
Journal Article
2004m22(scFv)-ETA', a new recombinant anti-CD64 immunotoxin for specific elimination of AML cells
Tur, M.K.; Huhn, M.; Thepen, T.; Stöcker, M.; Krohn, R.; Vogel, S.; Jost, E.; Osieka, R.; Winkel, J.G. van de; Fischer, R.; Barth, S.
Journal Article
2004Measurement of antibody-membrane interactions by surface plasmon resonance
Klimka, A.; Tur, M.K.; Huhn, M.; Bierfreund, U.; Terrada, E.; Fischer, R.; Finnern, R.; Barth, S.
Journal Article
2004Metalloproteinase inhibition augments anti-tumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo
Matthey, B.; Borchmann, P.; Schnell, R.; Tawadros, S.; Lange, H.; Tur, M.K.; Huhn, M.; Klimka, A.; Barth, S.; Engert, A.; Hansen, H.P.
Journal Article
2003A novel approach for immunization, screening and characterization of selected scFv libraries using membrane fractions of tumor cells
Tur, M.K.; Rothe, A.; Huhn, M.; Goerres, U.; Klimka, A.; Stocker, M.; Engert, A.; Fischer, R.; Finnern, R.; Barth, S.
Journal Article
2003The recombinant anti-EGF receptor immunotoxin 425(scFv)-ETA' suppresses growth of a highly metastatic pancreatic carcinoma cell line
Bruell, D.; Stöcker, M.; Huhn, M.; Redding, N.; Küpper, M.; Schumacher, P.; Paetz, A.; Bruns, C.J.; Haisma, H.J.; Fischer, R.; Finnern, R.; Barth, S.
Journal Article
2003Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells
Tur, M.K.; Huhn, M.; Thepen, T.; Stocker, M.; Krohn, R.; Vogel, S.; Jost, E.; Osieka, R.; Winkel, J.G. van de; Fischer, R.; Finnern, R.; Barth, S.
Journal Article
2002The in vitro anti-inflammatory effects of recombinant anti-CD25 immunotoxin on lamina propria T cells of patients with inflammatory bowel disease are not sufficient to cure experimental colitis in mice
Pfister, K.; Wittig, B.M.; Jüngling, B.; Ecker, K.W.; Barth, S.; Huhn, M.; Sasse, S.; Engert, A.; Mueller-Molaian, I.; Diehl, V.; Zeitz, M.; Stallmach, A.
Journal Article
2001An anti-GD2 single chain Fv selected by phage display and fused to Pseudomonas exotoxin A develops specific cytotoxic activity against neuroblastoma derived cell lines
Tur, M.K.; Sasse, S.; Stöcker, M.; Djabelkhir, K.; Huhn, M.; Matthey, B.; Gottstein, C.; Engert, A.; Barth, S.
Journal Article
2001Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma
Huhn, M.; Sasse, S.; Tur, M.K.; Matthey, B.; Schinköthe, T.; Rybak, S.; Barth, S.; Engert, A.
Journal Article
2001Selection of scFv phages on intact cells under low pH conditions leads to a significant loss of insert-free phages
Tur, M.K.; Huhn, M.; Sasse, S.; Engert, A.; Barth, S.
Journal Article
2000Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions
Barth, S.; Huhn, M.; Matthey, B.; Klimka, A.; Galinski, E.A.; Engert, A.
Journal Article
2000Ki-4(scFv)-ETA'. A new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice
Barth, S.; Huhn, M.; Matthey, B.; Tawadros, S.; Schnell, R.; Diehl, V.; Engert, A.
Journal Article