Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2017Human MAP tau based targeted cytolytic fusion proteins
Akinrinmade, O.A.; Jordaan, S.; Hristodorov, D.; Mladenov, R.; Mungra, N.; Chetty, S.; Barth, S.
Journal Article
2016CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo
Mladenov, R.; Hristodorov, D.; Cremer, C.; Gresch, G.; Grieger, G.; Schenke, L.; Klose, D.; Amoury, M.; Woitok, M.; Jost, E.; Brümmerdorf, T.H.; Fendel, R.; Fischer, R.; Stein, C.; Thepen, T.; Barth, S.
Journal Article
2016Fully human MAP-fusion protein selectively targets and eliminates proliferating CD64+ M1 macrophages
Hristodorov, D.; Mladenov, R.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2016Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model
Amoury, M.; Kolberg, K.; Pham, A.-T.; Hristodorov, D.; Mladenov, R.; Fiore, S. di; Helfrich, W.; Kiessling, F.; Fischer, R.; Pardo, A.; Thepen, T.; Hussain, A.F.; Nachreiner, T.; Barth, S.
Journal Article
2016A novel approach for targeted elimination of CSPG4-positive triple-negative breast cancer cells using a MAP tau-based fusion protein
Amoury, M.; Mladenov, R.; Nachreiner, T.; Pham, A.-T.; Hristodorov, D.; Di Fiore, S.; Helfrich, W.; Pardo, A.; Fey, G.; Schwenkert, M.; Thepen, T.; Kiessling, F.; Hussain, A.F.; Fischer, R.; Kolberg, K.; Barth, S.
Journal Article
2015The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia
Mladenov, R.; Hristodorov, D.; Cremer, C.; Hein, L.; Kreutzer, F.; Stroisch, T.; Niesen, J.; Brehm, H.; Blume, T.; Brummendorf, T.H.; Jost, E.; Thepen, T.; Fischer, R.; Stockmeyer, B.; Barth, S.; Stein, C.
Journal Article
2015Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein
Brehm, H.; Hristodorov, D.; Pardo, A.; Mladenov, R.; Niesen, J.; Fischer, R.; Tur, M.K.; Barth, S.
Journal Article
2015Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies
Hristodorov, D.; Mladenov, R.; Felbert, V. von; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2014 Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody
Hristodorov, D.; Mladenov, R.; Brehm, H.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2014EpCAM-Selective Elimination of Carcinoma Cells by a Novel MAP-Based Cytolytic Fusion Protein
Hristodorov, D.; Amoury, M.; Mladenov, R.; Niesen, J.; Arens, K.; Berges, N.; Hein, L.; Fiore, S. di; Pham, A.T.; Huhn, M.; Helfrich, W.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2014Human Cytolytic Fusion Proteins
Berges, N.; Hehmann-Titt, G.; Hristodorov, D.; Melmer, G.; Thepen, T.; Barth, S.
Journal Article
2014Human microtubule-associated protein tau mediates targeted killing of CD30+ lymphoma cells in vitro and inhibits tumour growth in vivo
Hristodorov, D.; Nordlohne, J.; Mladenov, R.; Huhn, M.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2013CD64-mediated specific elimination of M1-polarized macrophages : implications for therapeutic intervention in chronic inflammatory disease
Hristodorov, D.
Dissertation
2013Generation and comparative characterization of glycosylated and aglycosylated human IgG1 antibodies
Hristodorov, Dmitrij; Fischer, Rainer; Joerissen, Hannah; Müller-Tiemann, Beate; Apeler, Heiner; Linden, Lars
Journal Article
2013Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells
Schiffer, S.; Letzian, S.; Jost, E.; Mladenov, R.; Hristodorov, D.; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2013Macrophage-targeted therapy of chronic wounds
Hristodorov, D.; Mladenov, R.; Aslanian, E.; Huhn, M.; Barth, S.; Thepen, T.
Book Article
2013Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo
Hristodorov, D.; Mladenov, R.; Pardo, A.; Pham, A.-T.; Huhn, M.; Fischer, R.; Thepen, T.; Barth, S.
Journal Article
2013Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages
Schiffer, S.; Hristodorov, D.; Mladenov, R.; Aslanian, E.; Huhn, M.; Fischer, R.; Barth, S.; Thepen, T.
Journal Article
2013With or without sugar? (A)glycosylation of therapeutic antibodies
Hristodorov, D.; Fischer, R.; Linden, L.
Journal Article
2012Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases. Review
Hristodorov, D.; Mladenov, R.; Huhn, M.; Barth, S.; Thepen, T.
Journal Article