Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2017Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model
Steffen, L.; Ruppert, C.; Hoymann, H.-G.; Funke, M.; Ebener, S.; Kloth, C.; Mühlfeld, C.; Ochs, M.; Knudsen, L.; Lopez-Rodriguez, E.
Journal Article
2017Translation of angiotensin-converting enzyme 2 upon liver- and lung-targeted delivery of optimized chemically modified mRNA
Schrom, E.; Huber, M.; Aneja, M.; Dohmen, C.; Emrich, D.; Geiger, J.; Hasenpusch, G.; Herrmann-Janson, A.; Kretzschmann, V.; Mykhailyk, O.; Pasewald, T.; Oak, P.; Hilgendorff, A.; Wohlleber, D.; Hoymann, H.-G.; Schaudien, D.; Plank, C.; Rudolph, C.; Kubisch-Dohmen, R.
Journal Article
2015TRPA1-Agonists: Novel bronchodilators?
Haider, G.; Lee, J.-H.; Wiegand, S.; Spies, E.; Hoymann, H.-G.; Kummer, W.; Braun, A.; Nassenstein, C.
Journal Article
2013Toxicity profile of the GATA-3-specific DNAzyme hgd40 after inhalation exposure
Fuhst, R.; Runge, F.; Buschmann, J.; Ernst, H.; Praechter, C.; Hansen, T.; Erichsen, J. von; Turowska, A.; Hoymann, H.-G.; Müller, M.; Pohlmann, G.; Sewald, K.; Ziemann, C.; Schlüter, G.; Garn, H.
Journal Article
2010Assessment of pulmonary function and serum substance levels in newborn and juvenile rats
Lewin, G.; Hoymann, H.-G.; Fuhst, R.; Berger-Preiß, E.; Pohlmann, G.; Buschmann, J.
Journal Article
2009Assessing lung function and pharmacokinetics in neonatal and young rats
Lewin, G.; Hoymann, H.-G.; Fuhst, R.; Berger-Preiss, E.; Pohlmann, G.; Buschmann, J.
Journal Article, Conference Paper
2009Effects of the phosphodiesterase type 4 inhibitor roflumilast on early and late allergic response and airway hyperresponsiveness in aspergillus-fumigatus-sensitized mice
Hoymann, H.-G.; Wollin, L.; Müller, M.; Korolewitz, R.; Krug, N.; Braun, A.; Beume, R.
Journal Article
2008Impact of boostering for the strength of asthma parameters and dendritic cell numbers in a C57BL/6 model of allergic airway inflammation
Hartwig, C.; Constabel, H.; Neumann, D.; Hoymann, H.-G.; Tschernig, T.; Behrens, G.M.N.
Journal Article
2008Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
Srivastava, M.; Steinwede, K.; Kiviranta, R.; Morko, J.; Hoymann, H.-G.; Länger, F.; Buhling, F.; Welte, T.; Maus, U.A.
Journal Article
2003Effect of anti-nerve growth factor on early and late airway responses in allergic rats
Glaab, T.; Hoymann, H.-G.; Hecht, M.; Korolewitz, R.; Tschernig, T.; Hohlfeld, J.M.; Krug, N.; Braun, A.
Journal Article
2003Increase of inactive intra-alveolar surfactant subtypes in lungs of asthmatic Brown Norway rats
Schmiedl, A.; Hoymann, H.-G.; Ochs, M.; Menke, A.; Fehrenbach, A.; Krug, N.; Tschernig, T.; Hohlfeld, J.M.
Journal Article
2000Cutting edge: Guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: Evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma
Bautsch, W.; Hoymann, H.-G.; Zhang, Q.; Meier-Wiedenbach, I.; Raschke, U.; Ames, R.S.; Sohns, B.; Flemme, N.; Meyer zu Vilsendorf, A.; Grove, M.; Klos, A.; Köhl, J.
Journal Article
2000Investigation of chronic toxic and carcinogenic effects of gasoline engine exhausts deriving from fuel without and with ferrocene additive
Peters, L.; Ernst, H.; Koch, W.; Bartsch, W.; Bellmann, B.; Creutzenberg, O.; Hoymann, H.-G.; Dasenbrock, C.; Heinrich, U.
Journal Article
1999Dysfunction of pulmonary surfactant in asthmatics after segmental allergen challenge
Hohlfeld, J.M.; Ahlf, K.; Enhorning, G.; Balke, K.; Erpenbeck, V.J.; Petschallies, J.; Hoymann, H.-G.; Fabel, H.; Krug, N.
Journal Article
1998Effects of budesonide on airway hyperreactivity and inflammatory response in a rat model of allergic asthma
Hoymann, H.-G.; Hecht, M.; Emmendörffer, A.; Hohlfeld, J.; Bartsch, W.
Conference Paper
1998Einsatz immunologischer Methoden beim experimentell induzierten allergischem Asthma
Hecht, M.; Steinmüller, C.; Hoymann, H.-G.; Emmendörffer, A.
Conference Paper
1998Korrelation zwischen Lungenfunktion und zytologisch-biochemischen Parametern in einem Allergiemodell
Hoymann, H.-G.; Hecht, M.; Steinmüller, C.; Bartsch, W.; Ernst, H.
Conference Paper
1998Lung function changes in rats after chronic inhalation exposure to 4,4'-methylenediphenyldiisocyanate (MDI)
Hoymann, H.-G.; Creutzenberg, O.; Ernst, H.; Hohlfeld, J.; Heinrich, U.
Conference Paper
1998Measurement of lung function in rodents in vivo
Hoymann, H.-G.; Heinrich, U.
Book Article
1998Pulmonary lesions in Wistar rats associated with chronic inhalation of 4,4'-methylene-diphenyl-diisocyanate (MDI)
Ernst, H.; Hoymann, H.-G.; Rittinghausen, S.; Mohr, U.; Heinrich, U.
Conference Paper
1997Aerosolized surfactant inhibits acetylcholine-induced airway obstruction in rats
Hohlfeld, J.; Hoymann, H.-G.; Molthan, J.; Fabel, H.; Heinrich, U.
Journal Article
1997Chronic inhalation toxicity and carcinogenicity of 4,4-methylenediphenyldiisocyanate (MDI) in rats
Hoymann, H.-G.; Buschmann, J.; Ernst, H.; Bartsch, W.; Creutzenberg, O.; Bellmann, B.; Dasenbrock, C.; Koch, W.; Preiß, A.; Heinrich, U.
Journal Article
199632P-Postlabeling of a DNA adduct derived from 4,4'-methylenedianiline in the olfactory epithelium of rats exposed by inhalation to 4,4'methylenephenyl diisocyanate
Vock, E.H.; Hoymann, H.-G.; Heinrich, U.; Lutz, W.K.
Journal Article
1995Hemoglobin adducts and urine metabolites of 4,4'-methylenedianiline after 4,4'-methylenediphenyl diisocyanate exposure of rats
Sepai, O.; Schütze, D.; Heinrich, U.; Hoymann, H.-G.; Henschler, D.; Sabbioni, G.
Journal Article
1994Aerosolized surfactant inhibits acetylcholine-induced bronchoconstruction in rats
Hohlfeld, J.; Molthan, J.; Hoymann, H.-G.; Fabel, H.; Heinrich, U.
Conference Paper
1994Bronchoconstriction induced by aerosolized acetylcholine but not by acetylcholine given intravenously is inhibited by aerosolized surfactant in rats
Hohlfeld, J.; Molthan, J.; Hoymann, H.-G.; Fabel, H.; Heinrich, U.
Conference Paper
1994Comparative investigation of the effects of zardaverine and theophylline on pulmonary function in rats
Hoymann, H.-G.; Heinrich, U.; Beume, R.; Kilian, U.
Journal Article
1994Der Effekt von inhaliertem Terbutalin auf die Acetylcholin-induzierte Bronchokonstriktion wird durch vernebeltes Surfactant nicht verstärkt
Hohlfeld, J.; Molthan, J.; Hoymann, H.-G.; Fabel, H.; Heinrich, U.
Conference Paper
1994Inhalation exposure of rats to tar/pitch condensation aerosol or carbon black alone or in combination with irritant gases
Heinrich, U.; Peters, L.; Creutzenberg, O.; Dasenbrock, C.; Hoymann, H.-G.
Conference Paper
1994Type A natriuretic peptides exhibit different bronchoprotective effects in rats
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.; Forssmann, W.-G.
Journal Article
1993Effects of single and combined, subchronic exposure to ozone and soot particles on pulmonary surfactant phospholipids, associated protein A and on surface activity in rat lung lavage fluid
Klingebiel, R.; Heinrich, U.; Martin-Carrera, I.; Dettmer, M.; Kühn, A.; Bartsch, W.; Hoymann, H.-G.
Conference Paper
1992Effects of single and combined, subchronic exposure to ozone and soot particles on the pulmonary surfactant system and lung mechanics in rats
Klingebiel, R.; Heinrich, U.; Dettmer, M.; Martin-Carrera, I.; Hoymann, H.-G.; Kühne, A.; Bartsch, W.
Conference Paper
1992Protective effect of urodilatin (URO) or ANP against an acetylcholine(ACH)-induced bronchoconstriction in the rat in vivo
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.F.
Conference Paper, Journal Article
1992Standardization of aerosol delivery with a new aerosol generating device for use in animal physiology
Hohlfeld, J.; Hoymann, H.-G.; Koch, W.; Klingebiel, R.; Heinrich, U.
Conference Paper
1991Comparison of the protective effect of intravenous urodilatin (URO) or ANP against an acetylcholine(ACh)-induced bronchoconstriction in the rat in vivo
Flüge, T.; Hoymann, H.-G.; Hohlfeld, J.; Heinrich, U.; Fabel, H.; Wagner, T.O.F.
Journal Article
1991Effects of 12 weeks exposure to a diisocyanate -MDI- on the pulmonary surfactant system and bronchoalveolar cell content in rats
Klingebiel, R.; Creutzenberg, O.; Hoymann, H.-G.; Dettmer, M.; Schüler, T.; Heinrich, U.
Conference Paper
1989Pulmonary function changes in rats after chronic and subchronic inhalation exposure to various particulate matter
Heinrich, U.; Hoymann, H.-G.; Mermelstein, R.; Muhle, H.
Journal Article