Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Generation of porous 3D-scaffolds based on electrospun nanofibers
Weigel, Tobias; Schmitz, Tobias; Jannasch, Maren; Schürlein, Sebastian; Al-Hijailan, Reem; Suliman, Salwa; Walles, Heike; Hansmann, Jan
Abstract
2019An in vitro model mimics the contact of biomaterials to blood components and the reaction of surrounding soft tissue
Jannasch, Maren; Gaetzner, Sabine; Groeber, Florian; Weigel, Tobias; Walles, Heike; Schmitz, Tobias; Hansmann, Jan
Journal Article
2018Advanced dynamic cell and tissue culture
Hansmann, Jan; Egger, Dominik; Kasper, Cornelia
Journal Article
2018Comparative characterization of two galectins excreted-secreted from intestine-dwelling parasitic versus free-living females of the soil-transmitted nematode Strongyloides
Ditgen, Dina; Anandarajah, Emmanuela M.; Reinhardt, Anika; Younis, Abuelhassan Elshazly; Witt, Susanne; Hansmann, Jan; Lorenz, Eva; García-Hernández, Marisela; Paclik, Daniela; Soblik, Hanns; Jolodar, Abbas; Seeberger, Peter H.; Liebau, Eva; Brattig, Norbert W.
Journal Article
2018Deformation strain is the main physical driver for skeletal precursors to undergo osteogenesis in earlier stages of osteogenic cell maturation
Ramani-Mohan, Ram-Kumar; Schwedhelm, Ivo; Finne-Wistrand, Anna; Krug, Melanie; Schwarz, Thomas; Jakob, Franz; Walles, Heike; Hansmann, Jan
Journal Article
2018In vivo-like culture conditions in a bioreactor facilitate improved tissue quality in corneal storage
Schmid, Richard; Tarau, Ioana-Sandra; Rossi, Angela; Leonhardt, Stefan; Schwarz, Thomas; Schürlein, Sebastian; Lotz, Christian; Hansmann, Jan
Journal Article
2018Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation
Lotz, Christian; Kiesewetter, L.; Schmid, Freia F.; Hansmann, Jan; Walles, Heike; Groeber-Becker, Florian Kai
Journal Article
2018A standardized method based on pigmented epidermal models evaluates sensitivity against UV-irradiation
Schmid, Freia F.; Groeber-Becker, Florian; Schwab, Stefanie; Thude, Sibylle; Goebeler, Matthias; Walles, Heike; Hansmann, Jan
Journal Article
2018A three-dimensional hybrid pacemaker electrode seamlessly integrates into engineered, functional human cardiac tissue in vitro
Weigel, Tobias; Schmitz, Tobias; Pfister, Tobias; Gaetzner, Sabine; Jannasch, Maren; Al-Hijailan, Reem; Schürlein, Sebastian; Suliman, Salwa; Mustafa, Kamal; Hansmann, Jan
Journal Article
2017A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial
Jannasch, Maren; Gätzner, Sabine; Weigel, Tobias; Walles, Heike; Schmitz, Tobias; Hansmann, Jan
Journal Article
2017Flexible tissue-like electrode as a seamless tissue-electronic interface
Weigel, T.; Pfister, T.; Schmitz, T.; Jannasch, M.; Schürlein, S.; Hijailan, R.A.; Walles, H.; Hansmann, J.
Journal Article
2017High-Throughput Screening Techniques
Brendtke, R.; Wever, B. de; Groeber, F.; Hansmann, J.; Schmid, F.; Walles, H.
Book Article
2017In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction
Jannasch, Maren; Weigel, Tobias; Engelhardt, Lisa; Wiezoreck, Judith; Gaetzner, Sabine; Walles, Heike; Schmitz, Tobias; Hansmann, Jan
Journal Article
2017Innovativer Fräsroboter mit Direktantrieben
Uhlmann, E.; Reinkober, S.; Stürmer, Philipp Sven von; Hansmann, J.; Epping, M.
Journal Article
2017A multilayered electrospun graft as vascular access for hemodialysis
Radakovic, Dejan; Reboredo, Jenny W.; Helm, M.; Weigel, Tobias; Schürlein, Sebastian; Kupczyk, E.; Leyh, Rainer G.; Walles, Heike; Hansmann, Jan
Journal Article
2017Tissue Engineering of primary human in vitro models – Influence of mechanical and biochemical stimulation on tissue functionality
Appelt-Menzel, Antje; Zdzieblo, Daniela; Schürlein, Sebastian; Schwarz, Thomas; Hansmann, Jan; Metzger, Marco; Walles, Heike
Abstract
2017A versatile modular bioreactor platform for Tissue Engineering
Schürlein, Sebastian; Schwarz, Thomas; Krziminski, Steffan; Gätzner, Sabine; Hoppensack, Anke; Schwedhelm, Ivo; Schweinlin, Matthias; Walles, Heike; Hansmann, Jan
Journal Article
2017Vorrichtung und Verfahren zur Beeinflussung einer dynamischen Eigenschaft wenigstens eines beweglich gelagerten Körpers sowie deren Verwendung als variabel einstellbares Dämpfungselement
Hansmann, Jan; Wolter, Stefan; Seipel, Björn; Kaal, William; Herold, Sven
Patent
2016Development of an advanced primary human in vitro model of the small intestine
Schweinlin, Matthias; Wilhelm, Sabine; Schwedhelm, Ivo; Hansmann, Jan; Rietscher, Rene; Jurowich, Christian; Walles, Heike; Metzger, Marco
Journal Article
2016Evaluation of various bioreactor process systems for the production of induced pluripotent stem cells
Appelt-Menzel, Antje; Schwedhelm, Ivo; Kühn, Fabian; Cubukova, Alevtina; Edenhofer, Frank; Walles, Heike; Hansmann, Jan
Journal Article
2016Feasibility study on a microwave-based sensor for measuring hydration level using human skin models
Brendtke, R.; Wiehl, M.; Groeber, F.; Schwarz, T.; Walles, H.; Hansmann, J.
Journal Article
2016A first vascularized skin equivalent for as an alternative to animal experimentation
Groeber, Florian; Engelhardt, Lisa; Lange, Julia; Kurdyn, Szymon; Schmid, Freia F.; Rücker, Christoph; Mielke, Stephan; Walles, Heike; Hansmann, Jan
Journal Article
2016Hybrid cell detachment-free cell expansion system for adherent cell culturing and related proceeding protocol
Confalonieri, Davide; Hansmann, Jan; Walles, Heike; Krziminski, Steffan
Patent
2016Measuring average rheological quantities of cell monolayers in the linear viscoelastic regime
Dakhil, Haider; Gilbert, Daniel F.; Malhotra, Deepika; Limmer, Anja; Engelhardt, Hannes; Amtmann, Anette; Hansmann, Jan; Hübner, Holger; Buchholz, Rainer; Friedrich, Oliver; Wierschem, Andreas
Journal Article
2016Mimicking metastases including tumor stroma: A new technique to generate a three-dimensional colorectal cancer model based on a biological decellularized intestinal scaffold
Nietzer, Sarah; Baur, Florentin; Sieber, Stefan; Hansmann, Jan; Schwarz, Thomas; Stoffer, Carolin; Häfner, Heide; Gasser, Martin; Waaga-Gasser, Ana Maria; Walles, Heike; Dandekar, Gudrun
Journal Article
2016Monitoring der Substanzwirkung bei in vitro Geweben
Groeber, Florian; Hansmann, Jan; Walles, Heike
Patent
2016SPARC (secreted protein acidic and rich in cysteine) of the intestinal nematode Strongyloides ratti is involved in mucosa-associated parasite-host interaction
Anandarajah, Emmanuela M.; Ditgen, Dana; Hansmann, Jan; Erttmann, Klaus D.; Liebau, Eva; Brattig, Norbert W.
Journal Article
2015Biovasc-term (R): A platform technology to engineer of vascularised human tissues
Walles, H.; Steinke, M.; Ruecker, C.; Hansmann, J.; Groeber, F.; Blunk, T.; Metzger, M.; Dandekar, G.; Pullig, O.
Conference Paper, Journal Article
2015Development and application of three-dimensional skin equivalents for the investigation of percutaneous worm invasion
Jannasch, M.; Groeber, F.; Brattig, N.W.; Unger, C.; Walles, H.; Hansmann, J.
Journal Article
2015Ex vivo osteo-chondral organ culture
Schwab, Andrea; Ehlicke, Franziska; Hansmann, Jan; Walles, Heike
Journal Article
2015Impedance spectroscopy for the non-destructive evaluation of In vitro epidermal models
Groeber, F.; Engelhardt, L.; Egger, S.; Werthmann, H.; Monaghan, M.; Walles, H.; Hansmann, J.
Journal Article
2015In vitro elastogenesis: Instructing human vascular smooth muscle cells to generate an elastic fiber-containing extracellular matrix scaffold
Hinderer, S.; Shen, N.; Ringuette, L.-J.; Hansmann, J.; Reinhardt, D.P.; Brucker, S.Y.; Davis, E.C.; Schenke-Layland, K.
Journal Article
2015A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects
Kleinhans, Claudia; Mohan, Ramkumar Ramani; Vacun, Gabriele; Schwarz, T.; Haller, B.; Sun, Yang; Kahlig, A.; Kluger, Petra; Finne-Wistrand, Anna.; Walles, Heike; Hansmann, Jan
Journal Article
2014Development of a magnetorheological damper with an in two ways adjustable magnetic field for an electrically powered car with wheel hub motors
Jackel, Marco; Hansmann, J.; Matthias, Michael; Melz, T.
Conference Paper
2014Development of nanoelectrodes for cell stimulation and reduced foreign body reaction
Weigel, Tobias; Schmitz, T.; Jannasch, Maren; Gätzner, S.; Walles, Heike; Hansmann, Jan
Abstract
2014Experimental study on active noise and active vibration control for a passenger car using novel piezoelectric engine mounts and electrodynamic inertial mass actuators
Kraus, Roman; Millitzer, Jonathan; Hansmann, J.; Wolter, Stefan; Jackel, Marco
Conference Paper
2014A mouse bone marrow stromal cell line with skeletal stem cell characteristics to study osteogenesis in vitro and in vivo
Raeth, S.; Sacchetti, B.; Siegel, G.; Mau-Holzmann, U.A.; Hansmann, J.; Vacun, G.; Hauk, T.G.; Pfizenmaier, K.; Hausser, A.
Journal Article
2013A bioreactor system for interfacial culture and physiological perfusion of vascularized tissue equivalents
Groeber, F.; Kahlig, A.; Loff, S.; Walles, H.; Hansmann, J.
Journal Article
2013Bioreactors in tissue engineering - Principles, applications and commercial constraints
Hansmann, J.; Groeber, F.; Kahlig, A.; Kleinhans, C.; Walles, H.
Journal Article
2013Energy regeneration systems in cell-free protein synthesis in vitro
Kahlig, Alexander; Schwedhelm, Ivo; Monaghan, Michael; Thein, Marcus; Hansmann, Jan
Book Article
2013In silico approaches for the identification of optimal culture condition for tissue engineered bone substitutes
Kahlig, A.; Hansmann, J.; Groeber, F.; Schwarz, T.; Weyhmuller, J.; Illig, A.; Kleinhans, C.; Walles, H.
Journal Article
2013Zellfreie Proteinsynthese - Potentiale und Herausforderungen
Hansmann, J.; Kahlig, A.; Werthmann, H.; Thein, M.
Journal Article
2012Auslegung Optimierung und Charakterisierung von dielektrischen Elastomeraktoren
Kaal, W.; Herold, S.; Hansmann, J.; Melz, T.
Journal Article
2012Bioreaktorsysteme im Tissue Engineering
Hansmann, J.; Groeber, F.; Kalig, A.; Schwarz, T.
Journal Article
2012Design of a compact multi-sensor system for non-invasive glucose monitoring using optical spectroscopy
Abdallah, Omar; Bolz, Armin; Hansmann, Jan; Walles, Heike; Hirth, Thomas
Conference Paper
2012Development of a vascularized skin equivalent with a physiological perfused vascular network
Groeber, F.K.; Hansmann, J.; Kaufmann, M.; Walles, H.
Conference Paper, Journal Article
2012Dynamic culture of human mesenchymal stem cells in a perfusion bioreactor on ß-TCP cylinder
Kleinhans, C.; Haller, B.; Kahlig, A.; Vacun, G.; Schanz, J.; Hansmann, J.; Walles, H.; Kluger, P.
Journal Article
2012Einstellbares Federelement für adaptierbaren Schwingungstilger
Hansmann, Jan; Kaal, William; Seipel, Björn; Melz, Tobias
Journal Article
2012Impedance spectroscopy - A tool for the characterization of skin equivalents
Hansmann, J.; Groeber, F.; Walles, H.
Conference Paper, Journal Article
2012Kreisringscheibe als Feder mit verstellbarer Steifigkeit
Kraus, Josef; Hansmann, J.
Journal Article
2012Oligonucleotide and parylene surface coating of polystyrene and ePTFE for improved endothelial cell attachment and hemocompatibility
Schleicher, M.; Hansmann, J.; Elkin, B.; Kluger, P.J.; Liebscher, S.; Huber, A.J.T.; Fritze, O.; Schille, C.; Müller, M.; Schenke-Layland, K.; Seifert, M.; Walles, H.; Wendel, H.-P.; Stock, U.A.
Journal Article
2012Optical spectroscopy and obstacles by non-invasive detection of glucose concentration by home monitoring
Abdallah, O.; Qananwah, Q.; Bolz, A.; Hansmann, J.; Walles, H.; Hirth, T.
Conference Paper
2012Technical design of a module for the continuous production of biochemical energy for cell-free protein synthesis
Kahlig, A.; Volkwein, W.; Seyfert, K.; Thein, M.; Hirth, T.; Hansmann, J.
Conference Paper, Journal Article
2012Tuneable spring element for an adaptable vibration absorber
Hansmann, J.; Kaal, William; Seipel, Björn; Melz, Tobias
Journal Article
2012Vorrichtung zur Übertragung oder Entkopplung von mechanischen Schwingungen
Hansmann, Jan; Kaal, William; Melz, Tobias; Seipel, Björn; Kraus, Roman
Patent
2011Angiogenetic structures in a 3-dimensional dynamic cultivation system
Hinderer, S.; Novosel, E.; Hansmann, J.; Kluger, P.; Walles, H.
Abstract
2011Development of a self sustaining adaptive mountainbike shock absorber system as an example for simulation and optimization of mechatronical-biomechanical coupled systems
Heller, Mario; Hansmann, Jan; Hanselka, Holger; Baca, Arnold
Conference Paper
2011Development of a vascularised skin equivalent
Groeber, F.K.; Hansmann, J.; Kaufmann, M.; Walles, H.
Abstract
2011Development of a vascularized skin equivalent
Groeber, F.; Hansmann, J.; Kaufmann, M.; Walles, H.
Abstract
2011Development of a vascularized skin equivalent
Groeber, F.; Hansmann, J.; Kaufmann, M.; Walles, H.
Abstract
2011Dielectric stack actuators with innovative electrode design
Kaal, William; Hansmann, J.; Herold, Sven
Conference Paper
2011Endothelialization of oligonucleotide coated diX AM surfaces for in vivo tissue engineering
Schleicher, M.; Hansmann, J.; Elkin, B.; Kluger, P.J.; Liebscher, S.; Huber, A.J.; Fitze, O.; Schenke-Layland, K.; Schille, C.; Hellmer, K.H.; Walles, H.; Wendel, H.-P.; Stock, U.A.
Abstract
2011Fluorescence spectroscopy by detection of glucose concentrations in DMEM-solutions and its perspectives for non-invasive measurement
Abdallah, O.; Qananwah, Q.; Bolz, A.; Hansmann, J.; Hinderer, S.; Mertsching, H.
Conference Paper
2011Wellenanordnung sowie Verfahren zum Weiterleiten von um eine Drehachse wirkenden Drehmomenten
Flaschenträger, David; Hansmann, Jan; Melz, T.
Patent
2010Induktion von Angiogenese in vitro durch modellbasierte Bioreaktortechnologie
Hansmann, J.
Dissertation
2010IR spectroscopy vs. Raman scattering by measurement of glucose concentration
Abdallahs, O.; Hansmann, J.; Bolz, A.; Mertsching, H.
Conference Paper
2010Vascularised human tissue models. A new approach for the refinement of biomedical research
Schanz, J.; Pusch, J.; Hansmann, J.; Walles, H.
Journal Article
2009Abloeseverfahren fuer adhaerente Zellen
Derichs, C.; Koropp, U.; Mertsching, H.; Kaufmann, M.; Hansmann, J.
Patent
2009Automatische Abtrennung von Partikeln aus einer Suspension
Pretzsch, F.; Koropp, U.; Mertsching, H.; Kaufmann, M.; Hansmann, J.
Patent
2009Bioreactor technology in cardiovascular tissue engineering
Mertsching, H.; Hansmann, J.
Book Article
2009Bioreaktorsystem
Derichs, C.; Koropp, U.; Hansmann, J.; Kaufmann, M.; Mertsching, H.
Patent
2009Development of a threedimensional trachea cell model
Hampel, M.; Dally, I.; Hansmann, J.; Mertsching, H.
Abstract
2009Generation and transplantation of an autologous vascularized bioartificial human tissue
Mertsching, H.; Schanz, J.; Steger, V.; Schandar, M.; Schenk, M.; Hansmann, J.; Dally, I.; Friedel, G.; Walles, T.
Journal Article
2009In vivo tissue engineering of heart valves using DNA-aptamers as capture molecules for circulating endothelial progenitor cells
Schleicher, M.; Kluger, P.; Hansmann, J.; Mack, A.F.; Fritze, O.; Mertsching, H.; Wendel, H.-P.; Ziemer, G.; Stock, U.A.
Abstract
2009Modulares Produktionssystem zur automatischen Herstellung von dreidimensionalen Gewebestrukturen
Mertsching, H.; Heymer, A.; Hansmann, J.; Kaufmann, M.; Reis, C.; Huchler, R.; Traube, A.; Stallkamp, J.; Pretzsch, F.; Derichs, C.; Koropp, U.; Marx, U.; Pilgermann, S.; Saxler, J.; Stolzing, A.
Patent
2009Pipettenkopf, Pipettiervorrichtung
Pretzsch, F.; Koropp, U.; Mertsching, H.; Kaufmann, M.; Hansmann, J.
Patent
20083D Zellsysteme - In vitro Testsysteme als Alternativemethode zu Tierversuchen in der pharmazeutischen und chemischen Industrie
Michaelis, J.; Schanz, J.; Hansmann, J.; Hampel, M.; Mertsching, H.
Book Article
2008Bioartifical human tissues as test systems for basic and applied research: the vascularised liver module
Schanz, J.; Linke, K.; Hansmann, J.; Mertsching, H.
Journal Article, Conference Paper
2008Bioreaktorenentwicklung für das Tissue Engineering
Hansmann, J.; Mertsching, H.
Journal Article
2008Development of a threedimensional Trachea Model
Hampel, M.; Hansmann, J.; Mertsching, H.
Conference Paper
2008Inducing in vitro angiogenesis for the generation of vascularized scaffolds
Schanz, J.; Hansmann, J.; Hampel, M.; Reis, C.; Michaelis, J.; Mertsching, H.
Conference Paper
2008Mikrofluidischer Bioreaktor
Herz, M.; Hansmann, J.; Holzhauer, P.; Richter, M.
Patent
2007Bioreactor for use in vascular tissue engineering
Hansmann, J.
Abstract
2007Development of a physiological three-dimensional intestinal test system
Michaelis, J.; Hansmann, J.; Mertsching, H.
Abstract
2007Engineered liver-like tissue on a capillarized matrix for applied research
Linke, K.; Schanz, J.; Hansmann, J.; Walles, T.; Brunner, H.; Mertsching, H.
Journal Article
2007In vitro three-dimensional trachea model
Brenner, M.; Hansmann, J.; Mertsching, H.
Abstract
2007In vitro three-dimensional tubular trachea model
Brenner, M.; Hansmann, J.; Weimer, M.; Brunner, H.; Mertsching, H.
Conference Paper, Journal Article
2006Vaskularisierte Trägersysteme für in vitro Testsysteme
Mertsching, H.; Hansmann, J.; Schanz, J.; Linke, K.; Brenner, M.; Michaelis, J.; Walles, T.
Conference Paper