Fraunhofer-Gesellschaft

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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Downstream processing of Cry4AaCter-induced inclusion bodies containing insect-derived antimicrobial peptides produced in Escherichia coli
Hoffmann, D.; Eckhardt, D.; Gerlach, D.; Vilcinskas, A.; Czermak, P.
Journal Article
2019Forced degradation studies to identify critical process parameters for the purification of infectious measles virus
Loewe, D.; Häussler, J.; Grein, T.A.; Dieken, H.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2019Process intensification for an insect antimicrobial peptide elastin-like polypeptide fusion produced in redox-engineered Escherichia coli
Joachim, M.; Maguire, N.; Schäfer, J.; Gerlach, D.; Czermak, P.
Journal Article
2019The therapeutic potential of the insect metalloproteinase inhibitor against infections caused by Pseudomonas aeruginosa
Eisenhardt, M.; Schlupp, P.; Höfer, F.; Schmidts, T.; Hoffmann, D.; Czermak, P.; Pöppel, A.-K.; Vilcinskas, A.; Runkel, F.
Journal Article
2019Two-step production of neofructo-oligosaccharides using immobilized heterologous aspergillus terreus 1f-fructosyltransferase expressed in Kluyveromyces lactis and native Xanthophyllomyces dendrorhous G6-fructosyltransferase
Burghardt, J.P.; Baas, M.; Gerlach, D.; Czermak, P.
Journal Article
2018Artificial neural network-assisted spectrophotometric method for monitoring fructo-oligosaccharides production
Erdős, B.; Grachten, M.; Czermak, P.; Kovács, Z.
Journal Article
2018Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells
Zitzmann, J.; Weidner, T.; Eichner, G.; Salzig, D.; Czermak, P.
Journal Article
2018High cell density cultivation of Δgor/ΔtrxB E. coli in a chemically defined minimal medium with an enhanced iron concentration
Joachim, M.; Schäfer, J.G.; Gerlach, D.; Czermak, P.
Journal Article
2018High titer oncolytic measles virus production process by integration of dielectric spectroscopy as online monitoring system
Grein, T.A.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Journal Article
2018Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression
Zitzmann, J.; Schreiber, C.; Eichmann, J.; Bilz, R.O.; Salzig, D.; Weidner, T.; Czermak, P.
Journal Article
2017Anaerobic Membrane Bioreactor for Continuous Lactic Acid Fermentation
Fan, R.; Ebrahimi, M.; Czermak, P.
Journal Article
2017Baculovirus-induced recombinant protein expression in human mesenchymal stromal stem cells: A promoter study
Sprick, G.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2017The components of shear stress affecting insect cells used with the baculovirus expression vector system
Weidner, T.; Druzinec, D.; Mühlmann, M.; Buchholz, R.; Czermak, P.
Journal Article
2017A high-throughput expression screening platform to optimize the production of antimicrobial peptides
Schreiber, C.; Müller, H.; Birrenbach, O.; Klein, M.; Heerd, D.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2017Mannheimia haemolytica growth and leukotoxin production for vaccine manufacturing - a bioprocess review
Oppermann, T.; Busse, N.; Czermak, P.
Journal Article
2017Microcarrier choice and bead-to-bead transfer for human mesenchymal stem cells in serum-containing and chemically defined media
Leber, J.; Barekzai, J.; Blumenstock, M.; Pospisil, B.; Salzig, D.; Czermak, P.
Journal Article
2017Modeling the design and operational mode of a continuous membrane reactor for enzymatic lignin modification
Busse, N.; Kraume, M.; Czermak, P.
Journal Article
2017Non-invasive raman spectroscopy and quantitative real-time PCR distinguish among undifferentiated human mesenchymal stem cells and redifferentiated nucleus pulposus cells and chondrocytes In Vitro
Ehlicke, F.; Köster, N.; Salzig, D.; Czermak, P.
Journal Article
2017Optimal permeate flux for an enzymatic oxidation of technical lignins in a membrane reactor
Busse, N.; Kraume, M.; Czermak, P.
Journal Article
2017Optimized expression of the antimicrobial protein Gloverin from Galleria mellonella using stably transformed Drosophila melanogaster S2 cells
Zitzmann, J.; Weidner, T.; Czermak, P.
Journal Article
2017Process engineering of insect cell expression systems
Weidner, T.; Zitzmann, J.; Druzinec, D.; Czermak, P.
Abstract
2017Reassessment of inclusion body-based production as a versatile opportunity for difficult-to-express recombinant proteins
Hoffmann, D.; Ebrahimi, M.; Gerlach, D.; Salzig, D.; Czermak, P.
Journal Article
2017Reprint of "Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion"
Grein, T.A.; Leber, J.; Blumenstock, M.; Petry, F.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2017Screening different host cell lines for the dynamic production of measles virus
Grein, T.A.; Schwebel, F.; Kress, M.; Loewe, D.; Dieken, H.; Salzig, D.; Weidner, T.; Czermak, P.
Journal Article
2016Attachment, growth, and detachment of human mesenchymal stem cells in a chemically defined medium
Salzig, D.; Leber, J.; Merkewitz, K.; Lange, M.C.; Köster, N.; Czermak, P.
Journal Article
2016Enzymatic production of prebiotic fructo-oligosteviol glycosides
Spohner, S.C.; Czermak, P.
Journal Article
2016A fast and simple assay to quantify bacterial leukotoxin activity
Oppermann, T.; Schwarz, S.; Busse, N.; Czermak, P.
Journal Article
2016Heterologous expression of Aspergillus terreus fructosyltransferase in Kluyveromyces lactis
Spohner, S.C.; Czermak, P.
Journal Article
2016Kluyveromyces lactis: An emerging tool in biotechnology
Spohner, S.C.; Schaum, V.; Quitmann, H.; Czermak, P.
Journal Article
2016Manufacturing of human umbilical cord mesenchymal stromal cells on microcarriers in a dynamic system for clinical use
Petry, F.; Smith, J.R.; Leber, J.; Salzig, D.; Czermak, P.; Weiss, M.L.
Journal Article
2016Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion
Grein, T.A.; Leber, J.; Blumenstock, M.; Petry, F.; Weidner, T.; Salzig, D.; Czermak, P.
Journal Article
2016The potential of the Galleria mellonella innate immune system is maximized by the co-presentation of diverse antimicrobial peptides
Bolouri Moghaddam, M.R.; Tonk, M.; Schreiber, C.; Salzig, D.; Czermak, P.; Vilcinskas, A.; Rahnamaeian, M.
Journal Article
2016Single-Step RNA Extraction from Different Hydrogel-Embedded Mesenchymal Stem Cells for Quantitative Reverse Transcription-Polymerase Chain Reaction Analysis
Köster, N.; Schmiermund, A.; Grubelnig, S.; Leber, J.; Ehlicke, F.; Czermak, P.; Salzig, D.
Journal Article
2016Treatment of enzyme-initiated delignification reaction mixtures with ceramic ultrafiltration membranes: Experimental investigations and modeling approach
Busse, N.; Fuchs, F.; Kraume, M.; Czermak, P.
Journal Article
2015Considerations for the process development of insect-derived antimicrobial peptide production
Müller, H.; Salzig, D.; Czermak, P.
Journal Article
2015Development of an insect metalloproteinase inhibitor drug carrier system for application in chronic wound infections
Eisenhardt, M.; Dobler, D.; Schlupp, P.; Schmidts, T.; Salzig, M.; Vilcinskas, A.; Salzig, D.; Czermak, P.; Keusgen, M.; Runkel, F.
Journal Article
2015Expression of enzymes for the usage in food and feed industry with Pichia pastoris
Spohner, S.C.; Müller, H.; Quitmann, H.; Czermak, P.
Journal Article
2015Lactic Acid Production in a Membrane Bioreactor System with Thermophilic Bacillus coagulans: Fouling Analysis of the Used Ceramic Membranes
Fan, R.; Ebrahimi, M.; Quitmann, H.; Czermak, P.
Journal Article
2015Micro-bubble aeration in turbulent stirred bioreactors: Coalescence behavior in Pluronic F68 containing cell culture media
Druzinec, D.; Salzig, D.; Kraume, M.; Czermak, P.
Journal Article
2015Oncolytic measles viruses produced at different scales under serum-free conditions
Weiss, K.; Gerstenberger, J.; Salzig, D.; Mühlebach, M.D.; Cichutek, K.; Pörtner, R.; Czermak, P.
Journal Article
2015A rapid method for an offline glycerol determination during microbial fermentation
Kuhn, J.; Müller, H.; Salzig, D.; Czermak, P.
Journal Article
2015Recombinant α-l-rhamnosidase from Aspergillus terreus in selective trimming of α-l-rhamnose from steviol glycosides
Spohner, S.C.; Zahn, D.; Schaum, V.; Quitmann, H.; Czermak, P.
Journal Article
2014Bioreactor Expansion of Human Mesenchymal Stem Cells According to GMP Requirements
Elseberg, C.L.; Salzig, D.; Czermak, P.
Book Article
2014hMSC production in disposable bioreactors in compliance with cGMP guidelines and PAT
Oppermann, T.; Leber, J.; Elseberg, C.; Salzig, D.; Czermak, P.
Journal Article
2013Optimization of insect cell based protein production processes - online monitoring, expression systems, scale up
Druzinec, D.; Salzig, D.; Brix, A.; Kraume, M.; Vilcinskas, A.; Kollewe, C.; Czermak, P.
Book Article
2011Regeneration of the intervertebral disc (IVD) using in vitro differentiated stem cells
Ehlicke, F.; Freimark, D.; Pudlas, M.; Dorresteijn, A.; Walles, H.; Czermak, P.
Abstract
1990Mass transfer and mathematical modelling of enzymatically catalyzed conversion in a dialysis membrane reactor
Bauer, W.; Czermak, P.
Conference Paper
1988Dialysis membrane reactors for enzymatic conversions in biotechnical processes - functional principles and examples for application.
Eberhard, G.; König, A.; Tretzel, J.; Reimerdes, E.H.; Bauer, W.; Czermak, P.
Conference Paper
1988Enzymkatalysierte Prozesse in Dialyse-Membranreaktoren
König, A.; Tretzel, J.; Reimerdes, E.H.; Bauer, W.; Czermak, P.
Journal Article