Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2021Human Mesenchymal Stromal Cells Are Resistant to SARS-CoV-2 Infection under Steady-State, Inflammatory Conditions and in the Presence of SARS-CoV-2-Infected Cells
Schäfer, R.; Spohn, G.; Bechtel, M.; Bojkova, D.; Baer, P.C.; Kuci, S.; Seifried, E.; Ciesek, S.; Cinatl, J.
Journal Article
2021A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization
Schultz, B.; Zaliani, A.; Ebeling, C.; Reinshagen, J.; Bojkova, D.; Lage-Rupprecht, V.; Karki, R.; Lukassen, S.; Gadiya, Y.; Ravindra, N.G.; Das, S.; Baksi, S.; Domingo-Fernandez, D.; Lentzen, M.; Strivens, M.; Raschka, T.; Cinatl, J.; DeLong, L.N.; Gribbon, P.; Geisslinger, G.; Ciesek, S.; Dijk, D. van; Gardner, S.; Kodamullil, A.T.; Fröhlich, H.; Peitsch, M.; Jacobs, M.; Hoeng, J.; Eils, R.; Claussen, C.; Hofmann-Apitius, M.
Journal Article
2021A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection
Ellinger, B.; Bojkova, D.; Zaliani, A.; Cinatl, J.; Claussen, C.; Westhaus, S.; Keminer, O.; Reinshagen, J.; Kuzikov, M.; Wolf, M.; Geisslinger, G.; Gribbon, P.; Ciesek, S.
Journal Article
2020Aprotinin Inhibits SARS-CoV-2 Replication
Bojkova, D.; Bechtel, M.; McLaughlin, K.-M.; McGreig, J.E.; Klann, K.; Bellinghausen, C.; Rohde, G.; Jonigk, D.; Braubach, P.; Ciesek, S.; Münch, C.; Wass, M.N.; Michaelis, M.; Cinatl, J., Jr
Journal Article
2020COVID-19-Related Coagulopathy - Is Transferrin a Missing Link?
McLaughlin, K.-M.; Bechtel, M.; Bojkova, D.; Münch, C.; Ciesek, S.; Wass, M.N.; Michaelis, M.; Cinatl, J.
Journal Article
2020Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication
Klann, K.; Bojkova, D.; Tascher, G.; Ciesek, S.; Münch, C.; Cinatl, J.
Journal Article
2020Lack of antiviral activity of darunavir against SARS-CoV-2
Meyer, S. De; Bojkova, D.; Cinatl, J.; Damme, E. Van; Buyck, C.; Loock, M. Van; Woodfall, B.; Ciesek, S.
Journal Article
2020Optimized qRT-PCR Approach for the Detection of Intra- and Extra-Cellular SARS-CoV-2 RNAs
Toptan, T.; Hoehl, S.; Westhaus, S.; Bojkova, D.; Berger, A.; Rotter, B.; Hoffmeier, K.; Cinatl, J.; Ciesek, S.; Widera, M.
Journal Article
2020Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Shin, D.; Mukherjee, R.; Grewe, D.; Bojkova, D.; Baek, K.; Bhattacharya, A.; Schulz, L.; Widera, M.; Mehdipour, A.R.; Tascher, G.; Geurink, P.P.; Wilhelm, A.; Heden van Noort, G.J. van der; Ovaa, H.; Müller, S.; Knobeloch, K.-P.; Rajalingam, K.; Schulman, B.A.; Cinatl, J.; Hummer, G.; Ciesek, S.; Dikic, I.
Journal Article
2020Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
Bojkova, D.; Klann, K.; Koch, B.; Widera, M.; Krause, D.; Ciesek, S.; Cinatl, J.; Münch, C.
Journal Article
2020SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
Bojkova, D.; Wagner, J.U.G.; Shumliakivska, M.; Aslan, G.S.; Saleem, U.; Hansen, A.; Luxan, G.; Günther, S.; Pham, M.D.; Krishnan, J.; Harter, P.N.; Ermel, U.H.; Frangakis, A.S.; Milting, H.; Zeiher, A.M.; Klingel, K.; Cinatl, J.; Dendorfer, A.; Eschenhagen, T.; Tschöpe, C.; Ciesek, S.; Dimmeler, S.
Journal Article
2019Selective Inactivation of Cancer Drugs by SAMHD1 Provides a Molecular Rationale for Therapeutic Stratification in AML
Schneider, C.; Oellerich, T.; Knecht, K.M.; Thomas, D.; Buzovetsky, O.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Geisslinger, G.; Keppler, O.T.; Xiong, Y.; Cinatl, J.
Journal Article
2019Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML
Oellerich, T.; Schneider, C.; Thomas, D.; Knecht, K.M.; Buzovetsky, O.; Kaderali, L.; Schliemann, C.; Bohnenberger, H.; Angenendt, L.; Hartmann, W.; Wardelmann, E.; Rothenburger, T.; Mohr, S.; Scheich, S.; Comoglio, F.; Wilke, A.; Ströbel, P.; Serve, H.; Michaelis, M.; Ferreiros, N.; Geisslinger, G.; Xiong, Y.; Keppler, O.T.; Cinatl, J.
Journal Article
2018The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
Knecht, K.M.; Buzovetsky, O.; Schneider, C.; Thomas, D.; Srikanth, V.; Kaderali, L.; Tofoleanu, F.; Reiss, K.; Ferreirós, N.; Geisslinger, G.; Batista, V.S.; Ji, X.; Cinatl, J.; Keppler, O.T.; Xiong, Y.
Journal Article
2017SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia
Schneider, C.; Oellerich, T.; Baldauf, H.-M.; Schwarz, S.-M.; Thomas, D.; Flick, R.; Bohnenberger, H.; Kaderali, L.; Stegmann, L.; Cremer, A.; Martin, M.; Lohmeyer, J.; Michaelis, M.; Hornung, V.; Schliemann, C.; Berdel, W.E.; Hartmann, W.; Wardelmann, E.; Comoglio, F.; Hansmann, M.L.; Yakunin, A.F.; Geisslinger, G.; Ströbel, P.; Ferreiros, N.; Serve, H.; Keppler, O.T.; Cinatl, J.
Journal Article
2010Enhanced drug targeting by attachment of an anti alpha v integrin antibody to doxorubicin loaded human serum albumin nanoparticles
Wagner, S.; Rothweiler, F.; Anhorn, M.G.; Sauer, D.; Riemann, I.; Weiss, E.C.; Katsen-Globa, A.; Michaelis, M.; Cinatl, J.; Schwartz, D.; Kreuter, J.; Briesen, H. von; Langer, K.
Journal Article