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Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP‐10 and MET
Kuo, C.-H.S.; Pavlidis, S.; Zhu, J.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Gibeon, D.; Hoda, U.; Sousa, A.; Wilson, S.J.; Howarth, P.; Shaw, D.; Fowler, S.; Dahlen, B.; Chanez, P.; Krug, N.; Sandstrom, T.; Fleming, L.; Corfield, J.; Auffray, C.; Djukanovic, R.; Sterk, P.J.; Guo, Y.; Adcock, I.M.; Chung, K.F.
Journal Article
2019Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Jevnikar, Z.; Östling, J.; Ax, E.; Calven, J.; Thörn, K.; Israelsson, E.; Öberg, L.; Singhania, A.; Lau, L.C.K.; Wilson, S.J.; Ward, J.A.; Chauhan, A.; Sousa, A.R.; Meulder, B. de; Loza, M.J.; Baribaud, F.; Sterk, P.J.; Chung, K.F.; Sun, K.; Guo, Y.; Adcock, I.M.; Payne, D.; Dahlen, B.; Chanez, P.; Shaw, D.E.; Krug, Norbert; Hohlfeld, Jens M.; Sandström, T.; Djukanovic, R.; James, A.; Hinks, T.S.C.; Howarth, P.H.; Vaarala, O.; Geest, M. van; Olsson, H.; Adcock, I.M.; Ahmed, H.; Auffray, C.; Bakke, P.; Bansal, A.T.; Baribaud, F.; Bates, S.; Bel, E.H.; Bigler, J.; Bisgaard, H.; Boedigheimer, M.J.; Bonnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Caruso, M.; Chaiboonchoe, A.; Chanez, P.; Chung, F.K.; Compton, C.H.; Corfield, J.; D'Amico, A.; Dahlen, S.E.; De Meulder, B.; Djukanovic, R.; Erpenbeck, V.J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L.J.; Formaggio, E.; Fowler, S.J.; Frey, U.; Gahlemann, M.; Geiser, T.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hedlin,
Journal Article
2019Identification and prospective stability of electronic nose (eNose) - derived inflammatory phenotypes in patients with severe asthma
Brinkman, P.; Wagener, A.H.; Hekking, P.-P.; Bansal, A.T.; Zee, A.-H. Maitland-van der; Wang, Y.; Weda, H.; Knobel, H.H.; Vink, T.J.; Rattray, N.J.; D'Amico, A.; Pennazza, G.; Santonico, M.; Lefaudeux, D.; Meulder, B. de; Auffray, C.; Bakke, P.S.; Caruso, M.; Chanez, P.; Chung, K.F.; Corfield, J.; Dahlén, S.-E.; Djukanovic, R.; Geiser, T.; Horvath, I.; Krug, Norbert; Musial, J.; Sun, K.; Riley, J.H.; Shaw, D.E.; Sandström, T.; Sousa, A.R.; Montuschi, P.; Fowler, S.J.; Sterk, P.J.
Journal Article
2018Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
Emma, Rosalia; Bansal, Aruna T.; Kolmert, Johan; Wheelock, Craig E.; Dahlén, Sven-Erik; Loza, Matthew J.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Dahlén, Barbro; Bakke, Per S.; Chanez, Pascal; Fowler, Stephen J.; Horvath, Ildiko; Montuschi, Paolo; Krug, Norbert; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Fleming, Louise J.; Djukanovic, Ratko; Howarth, Peter H.; Singer, Florian; Sousa, Ana R.; Sterk, Peter J.; Corfield, Julie; Pandis, Ioannis; Chung, Kian F.; Adcock, Ian M.; Lutter, René; Fabbella, Lorena; Caruso, Massimo
Journal Article
2018Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers
Brandsma, Joost; Goss, Victoria M.; Yang, Xian; Bakke, Per S.; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominick E.; Chung, Kian Fan; Singer, Florian; Fleming, Louise J.; Sousa, Ana R.; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Djukanović, Ratko; Postle, Anthony D.
Journal Article
2018Measures of adherence in patients with severe asthma prescribed systemic steroids in the U-BIOPRED cohort
Alahmadi, Fahad; Simpson, Andrew; Gomez, Christina; Wheelock, Craig; Shaw, Dominick E.; Fleming, Louise; Roberts, Graham; Riley, John; Bates, Stewart; Sousa, Ana R.; Knowles, Richard; Bansal, Aruna T.; Corfield, Julie; Pandis, Ioannis; Sun, Kai; Bakke, Per; Caruso, Massimo; Chanez, Pascal; Dahlen, Babro; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sandstrom, Thomas; Singer, Florian; Wagers, Scott; Adcock, Ian M.; Djukanović, Ratko; Chung, Kian Fan; Sterk, Peter J.; Dahlén, Sven-Erik; Fowler, Stephen J.
Abstract
2018Periostin expression in the U-BIOPRED severe asthma bronchoscopy cohort
Wilson, Susan Jane; Faruqi, Ali; Ward, Jonathan A.; Norman, Jenny; Sousa, Ana R.; Corfield, Julie; Sterk, Peter J.; Chung, Fan; Djukanović, Ratko; Dahlén, Barbro; Chanez, Pascal; Shaw, Dominick E.; Krug, Norbert; Sandstrom, Thomas; Howarth, Peter; Holweg, Cecile
Abstract
2018Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: An exploratory analysis
Takahashi, Kentaro; Pavlidis, Stelios; Ng Kee Kwong, Francois; Hoda, Uruj; Rossios, Christos; Sun, Kai; Loza, Matthew; Baribaud, Fred; Chanez, Pascal; Fowler, Steve J.; Horvath, Ildiko; Montuschi, Paolo; Singer, Florian; Musial, Jacek; Dahlén, Barbro; Dahlén, Sven-Erik; Krug, Norbert; Sandström, Thomas; Shaw, Dominick E.; Lutter, René; Bakke, Per; Fleming, Louise J.; Howarth, Peter H.; Caruso, Massimo; Sousa, Ana R.; Corfield, Julie; Auffray, Charles; Meulder, Bertrand de; Lefaudeux, Diane; Djukanovic, Ratko; Sterk, Peter J.; Guo, Yike; Adcock, Ian M.; Chung, Kian Fan
Journal Article
2018U-BIOPRED accessible handprint: Combining omics platforms to identify stable asthma subphenotypes
Meulder, Bertrand de; Yen, Romain Tching Chi; Li, Chuan-Xing; Wheelock, Asa; Chung, Kian Fan; Adcock, Ian M.; Djukanović, Ratko; Wagers, Scott; Riley, John; Erpenbeck, Veit J.; Bakke, Per; Caruso, Massimo; Chanez, Pascal; Dahlén, Sven-Erik; Fowler, Stephen J.; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Shaw, Dominic; Singer, Florian; Pandis, Ioannis; Bansal, Aruna T.; Sterk, Peter J.; Baribaud, Frédéric; Auffray, Charles
Abstract
2017A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED
Kuo, C.H.S.; Pavlidis, S.; Loza, M.; Baribaud, F.; Rowe, A.; Pandis, I.; Hoda, U.; Rossios, C.; Souse, A.; Wilson, S.J.; Howarth, P.; Dahlen, B.; Dahlen, S.E.; Chanez, P.; Shaw, D.; Krug, Norbert; Sandström, T.; Meulder, B. de; Lefaudeux, D.; Fowler, S.; Fleming, L.; Corfield, J.; Auffray, C.; Sterk, P.J.; Djukanovic, R.; Guo, Y.K.; Adcock, I.M.; Chung, K.F.
Journal Article
2017U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
Lefaudeux, D.; De Meulder, B.; Loza, M.J.; Peffer, N.; Rowe, A.; Baribaud, F.; Bansal, A.T.; Lutter, R.; Sousa, A.R.; Corfield, J.; Pandis, I.; Bakke, P.S.; Caruso, M.; Chanez, P.; Dahlén, S.-E.; Fleming, L.J.; Fowler, S.J.; Horvath, I.; Krug, N.; Montuschi, P.; Sanak, M.; Sandstrom, T.; Shaw, D.E.; Singer, F.; Sterk, P.J.; Roberts, G.; Adcock, I.M.; Djukanovic, R.; Auffray, C.; Chung, K.F.
Journal Article
2016Severe asthma exists despite suppressed tissue inflammation: Findings of the U-BIOPRED study
Wilson, Susan J.; Ward, Jonathan A.; Sousa, Ana R.; Corfield, Julie; Bansal, Aruna T.; Meulder, Bertrand de; Lefaudeux, Diane; Auffray, Charles; Loza, Matthew J.; Baribaud, Frédéric; Fitch, Neil; Sterk, Peter J.; Chung, Kian Fan; Gibeon, David; Sun, Kai; Guo, Yi-Ke; Adcock, Ian M.; Djukanovic, Ratko; Dahlén, Barbro; Chanez, Pascal; Shaw, Dominick E.; Krug, Norbert; Hohlfeld, Jens; Sandström, Thomas; Howarth, Peter H.
Journal Article
2015Airway remodelling in the U-BIOPRED severe asthma cohort
Wilson, S.; Ward, J.; Rigden, H.; Sousa, A.; Corfield, J.; Sterk, P.; Chung, K.F.; Ratko, D.; Dahlen, B.; Chanez, P.; Shaw, D.; Krug, N.; Sandstrom, T.; Howarth, P.
Abstract
2015Characteristics of the frequent exacerbator in U-BIOPRED adult severe asthma cohort
Hoda, U.; Sousa, A.; Corfield, J.; Shaw, D.; Fowler, S.; Fleming, L.; Seibold, W.; Bakke, P.; Garnier, C. von; Horvath, I.; Krug, N.; Dahlen, B.; Musial, J.; Chanez, P.; Montuschi, P.; Sandstrom, T.; Howarth, P.; Bel, E.; Bansal, A.; Pandis, I.; Kuo, C.H.; Djukanovic, R.; Sterk, P.; Roberts, G.; Chung, F.
Abstract
2015Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Shaw, Dominick E.; Sousa, Ana R.; Fowler, Stephen J.; Fleming, Louise J.; Roberts, Graham; Corfield, Julie; Pandis, Ioannis; Bansal, Aruna T.; Bel, Elisabeth H.; Auffray, Charles; Compton, Chris H.; Bisgaard, Hans; Bucchioni, Enrica; Caruso, Massimo; Chanez, Pascal; Dahlén, Barbro; Dahlén, Sven-Erik; Dyson, Kerry; Frey, Urs; Geiser, Thomas; Gerhardsson de Verdier, Maria; Gibeon, David; Guo, Yi-Ke; Hashimoto, Simone; Hedlin, Gunilla; Jeyasingham, Elizabeth; Hekking, Pieter-Paul W.; Higenbottam, Tim; Horváth, Ildikó; Knox, Alan J.; Krug, Norbert; Erpenbeck, Veit J.; Larsson, Lars X.; Lazarinis, Nikos; Matthews, John G.; Middelveld, Roelinde; Montuschi, Paolo; Musial, Jacek; Myles, David; Pahus, Laurie; Sandström, Thomas; Seibold, Wolfgang; Singer, Florian; Strandberg, Karin; Vestbo, Jorgen; Vissing, Nadja; Garnier, Christophe von; Adcock, Ian M.; Wagers, Scott; Rowe, Anthony; Howarth, Peter; Wagener, Ariane H.; Djukanovic, Ratko; Sterk, Peter J.; Chung, Kian Fan
Journal Article
2015The first U-BIOPRED blood handprint of severe asthma
Meulder, B. de; Lefaudeux, D.; Bigler, J.; Loza, M.J.; Wheelock, C.E.; Sousa, A.R.; Corfield, J.; Baribaud, F.; Auffray, C.; Shaw, D.E.; Horvath, I.; Musial, J.; Chanez, P.; Krug, N.; Montuschi, P.; Bakke, P.S.; Singer, F.; Fowler, S.J.; Dahlen, S.E.; Sandström, T.; Sterk, P.J.; Chung, K.F.; Adcock, I.M.; Djukanovic, R.
Abstract
2015The first U-BIOPRED sputum handprint of severe asthma
Lefaudeux, D.; Meulder, B. de; Loza, M.J.; Sanak, M.; Sousa, A.R.; Corfield, J.; Baribaud, F.; Shaw, D.E.; Horvath, I.; Musial, J.; Chanez, P.; Krug, N.; Montuschi, P.; Bakke, P.S.; Singer, F.; Fowler, S.J.; Dahlen, S.E.; Sandström, T.; Sterk, P.J.; Djukanovic, R.; Chung, K.F.; Adcock, I.M.; Auffray, C.
Abstract
2015Multivariate cluster analysis of immunopathological and clinical data from the U-BIOPRED severe asthma study: Preliminary results
Wilson, S.; Dimitrov, B.; Djukanovic, R.; Ward, J.; Sousa, A.; Corfield, J.; Sterk, P.; Chung, K.F.; Dahlen, B.; Chanez, P.; Shaw, D.; Krug, N.; Sandström, T.; Howarth, P.
Abstract
2015Prevalence Of Gastro-Oesophageal Reflux (GORD) And Associations With Clinical Phenotypic Markers In Adult Severe Asthmatics In The U-Biopred Cohort
Tariq, K.; Nicholas, B.L.; Lutter, R.; Bel, E.; Bansal, A.; Wagers, S.S.; Bisgaard, H.; Sandström, T.; Larsson, L.; Vestbo, J.; Montuschi, P.; Higgenbottam, T.W.; Compton, C.; Myles, D.; Chanez, P.; Pahus, L.; Murray, C.S.; Woodcock, A.; Musial, J.; Nordlund, B.; Hashimoto, S.; Hedlin, G.L.; Dahlen, S.E.K.; Middelveld, R.; Dahlen, B.; Krug, N.; Vissing, N.; Polosa, R.; Horvath, I.; Singer, F.; Bakke, P.; Roberts, G.; Fichtner, K.; Rowe, A.; Jeyasingham, E.; Riley, J.; Fleming, L.; Fowler, S.J.; Shaw, D.E.; Corfield, J.; Sousa, A.R.; Chung, K.; Howarth, P.H.; Sterk, P.J.; Djukanovic, R.
Abstract
2014Prevalence and phenotypic characteristics of severe adult-onset asthma in the U-Biopred cohort
Hekking, Pieter-Paul; Wagener, Ariane H.; Sousa, Ana R.; Fowler, Stephen J.; Bakke, Per; Frey, Urs; Krug, Norbert; Hashimoto, Simone; Woodcock, Ashley; Chanez, Pascal; Montuschi, Paolo; Bisgaard, Hans; Corfield, Julie; Howarth, Peter H.; Djukanovic, Ratko; Chung, Kian Fan; Fleming, Louise; Riley, John; Jeyasingham, Elisabeth; Fichtner, Klaus; Rowe, Anthony; Roberts, Graham; Singer, Florian; Geiser, Thomas; Horvath, Ildiko; Riccardo, Polosa; Vissing, Nadja H.; Dahlen, Babro; Musial, Jacek; Murray, Clare S.; Myles, David; Compton, Chris; Higenbottam, Tim W.; Vestbo, J.; Pahus, Laurie; Larsson, Lars; Sandstrom, Thomas; Shaw, Dominic; Wagers, Scott S.; Sterk, Peter J.; Bansal, Aruna T.; Bel, Elisabeth
Abstract
2013Associated factors with persistent airflow limitation in asthma in U-BIOPRED
Wagener, A.H.; Gibeon, D.; Yang, X.; Sousa, A.R.; Corfield, J.; Shaw, D.E.; Fowler, S.; Flemming, L.J.; Riley, J.; Jeyasingham, E.; Rowe, A.; Fichtner, K.; Robberts, G.; Bakke, P.; Singer, T.; Geiser, T.; Frey, U.; Horvarth, I.; Polosa, R.; Bonnelykke, K.; Krug, Norbert; Middelveld, R.; Dahlen, S.-E.; Dahlen, B.; Hedlin, G.; Hashimoto, S.; Nordlund, B.; Musial, J.; Woodcock, A.; Murray, C.S.; Pahus, L.; Chanez, P.; Myles, D.; Compton, C.; Higenbottam, T.W.; Montuschi, P.; Vestbo, J.; Larsson, L.; Sandstrom, T.; Bisgaard, H.; Wagers, S.S.; Howarth, P.H.; Bel, E.H.; Djukanovic, R.; Chung, K.F.; Sterk, P.J.
Journal Article, Conference Paper