Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Concise Review: Neuronal Stem Cell-Drug Interactions: A Systematic Review and Meta-Analysis
Ikhsan, M.; Palumbo, A.; Rose, D.; Zille, M.; Boltze, J.
Journal Article
2019Effects of pulmonary artery banding in doxorubicin-induced left ventricular cardiomyopathy
Yerebakan, C.; Boltze, J.; Elmontaser, H.; Yoruker, U.; Latus, H.; Khalil, M.; Ostermayer, S.; Steinbrenner, B.; Apitz, C.; Schneider, M.; Suchowski, M.; Ruetten, R.; Mueller, K.; Kerst, G.; Schranz, D.; Akintuerk, H.
Journal Article
2019Large animals in neurointerventional research: A systematic review on models, techniques and their application in endovascular procedures for stroke, aneurysms and vascular malformations
Herrmann, A.M.; Meckel, S.; Gounis, M.J.; Kringe, L.; Motschall, E.; Mülling, C.; Boltze, J.
Journal Article
2019A stereotaxic breed-averaged, symmetric T2w canine brain atlas including detailed morphological and volumetrical data sets
Nitzsche, B.; Boltze, J.; Ludewig, E.; Flegel, T.; Schmidt, M.J.; Seeger, J.; Barthel, H.; Brooks, O.W.; Gounis, M.J.; Stoffel, M.H.; Schulze, S.
Journal Article
2018Behavioral outcome measures to improve experimental stroke research
Balkaya, M.G.; Trueman, R.C.; Boltze, J.; Corbett, D.; Jolkkonen, J.
Journal Article
2018Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1
Müller, Bent; Boltze, Johannes; Czepezauer, Ivonne; Hesse, Volker; Wilcke, Arndt; Kirsten, Holger
Journal Article
2018Future of Animal Modeling for Poststroke Tissue Repair
Modo, M.M.; Jolkkonen, J.; Zille, M.; Boltze, J.
Journal Article
2018Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage
Boltze, Johannes; Ferrara, Fabienne; Hainsworth, Atticus H.; Bridges, Leslie R.; Zille, Marietta; Lobsien, Donald; Barthel, Henryk; Mcleod, Damian D.; Gräßer, Felix; Pietsch, Sören; Schatzl, Ann-Kathrin; Dreyer, Antje; Nietzsche, Björn
Journal Article
2018Optogenetics in stem cell research: Focus on the central nervous system
Boltze, J.; Stroh, A.
Book Article
2018Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges
Brockmann, I.; Ehrenpfordt, J.; Sturmheit, T.; Brandenburger, M.; Kruse, C.; Zille, M.; Rose, D.; Boltze, J.
Journal Article
2018Sulfur mustard skin lesions
Rose, D.; Schmidt, A.; Brandenburger, M.; Sturmheit, T.; Zille, M.; Boltze, J.
Journal Article
2017Astrocytic expression of the chemokine receptor CXCR7/ACKR3 in the diseased CNS
Engele, J.; Pelkner, F.; Stein, G.; Angelov, D.N.; Boltze, J.; Wagner, D.C.; Odoardi, F.; Flügel, A.; Puchert, M.
Abstract
2017Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS
Puchert, M.; Pelkner, F.; Stein, G.; Angelov, D.N.; Boltze, J.; Wagner, D.-C.; Odoardi, F.; Flügel, A.; Streit, W.J.; Engele, J.
Journal Article
2017ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR
Müller, Bent; Schaadt, Gesa; Boltze, Johannes; Emmrich, Frank; Skeide, Michael A.; Neef, Nicole; Kraft, Indra; Brauer, Jens; Friederici, Angela D.; Kirsten, Holger; Wilcke, Arndt
Journal Article
2017Concise review: Increasing the validity of cerebrovascular disease models and experimental methods for translational stem cell research
Boltze, J.; Nitzsche, F.; Jolkkonen, J.; Weise, G.; Pösel, C.; Nitzsche, B.; Wagner, D.-C.
Journal Article
2017Concise review: MSC adhesion cascade - insights into homing and transendothelial migration
Nitzsche, F.; Müller, C.; Lukomska, B.; Jolkkonen, J.; Deten, A.; Boltze, J.
Journal Article
2017Dyslexia risk gene relates to representation of sound in the auditory brainstem
Neel, Nicole E.; Müller, Bent; Liebig, Johanna; Schaadt, Gesa; Grigutsch, Maren; Gunter, Thomas C.; Wilcke, Arndt; Kirsten, Holger; Skeide, Michael A.; Kraft, Indra; Kraus, Nina; Emmrich, Frank; Brauer, Jens; Boltze, Johannes; Friederici, Angela D.
Journal Article
2017High-dosage granulocyte colony stimulating factor treatment alters monocyte trafficking to the brain after experimental stroke
Weise, G.; Pösel, C.; Möller, K.; Kranz, A.; Didwischus, N.; Boltze, J.; Wagner, D.C.
Journal Article
2017Immunosuppression for in vivo research
Diehl, Rita; Ferrara, Fabienne; Müller, Claudia; Dreyer, Antje Y.; McLeod, Damian D.; Fricke, Stephan; Boltze, Johannes
Journal Article
2017Integrin alpha4 Overexpression on Rat Mesenchymal Stem Cells Enhances Transmigration and Reduces Cerebral Embolism After Intracarotid Injection
Cui, L.-L.; Nitzsche, F.; Pryazhnikov, E.; Tibeykina, M.; Tolppanen, L.; Rytkönen, J.; Huhtala, T.; Mu, J.-W.; Khiroug, L.; Boltze, J.; Jolkkonen, J.
Journal Article
2017Recent progress in translational research on neurovascular and neurodegenerative disorders
Demuth, Hans-Ulrich; Dijkhuizen, Rick M.; Farr, Tracy D.; Gelderblom, Mathias; Horsburgh, Karen; Iadecola, Costantino; Mcleod, Damian D.; Michalski, Dominik; Murphy, Tim H.; Orbe, Josune; Otte, Wilem M.; Petzold, Gabor C.; Plesnila, Nikolaus; Reiser, Georg; Reymann, Klaus G.; Rueger, Maria P.; Saur, Dorothee; Savitz, Sean; Schilling, Stephan; Spratt, Neil J.; Turner, Renée J.; Vermuganti, Raghu; Vivien, Denis; Yepes, Manuel; Zille, Marietta; Boltze, Johannes
Journal Article
2017The role of SUMOylation in cerebral hypoxia and ischemia
Peters, Myriam; Wielsch, Betty; Boltze, Johannes
Journal Article
2017Towards Improved Translational Stroke Researc. Progress and Perspectives of the Recent National Institute of Neurological Disorders and Stroke Consensus Group Meeting
Zerna, C.; Hill, M.D.; Boltze, J.
Journal Article
2017Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells
Nowakowski, Adam; Andrzejewska, Anna; Boltze, Johannes; Nitzsche, Franziska; Cui, Li-li; Jolkkonen, Jukka; Walczak, Piotr; Lukomska, Barbara; Janowski, Miroslaw
Journal Article
2017Translational models for vascular cognitive impairment: A review including larger species
Hainsworth, Atticus H.; Allan, Stuart M.; Boltze, Johannes; Cunningham, Catriona; Farris, Chad; Head, Elizabeth; Ihara, Masafumi; Isaacs, Jeremy D.; Kalaria, Raj N.; Lesnik Oberstein, Saskia A.M.; Moss, Mark B.; Nitzsche, Björn; Rosenberg, Gary A.; Rutten, Julie W.; Salkovic-Petrisic, Melita; Troen, Aron M.
Journal Article
2016Academic-industry collaborations in translational stroke research
Boltze, Johannes; Wagner, Daniel-Christoph; Barthel, Henryk; Gounis, Matthew J.
Journal Article
2016Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort
Müller, Bent; Wilcke, Arndt; Czepezauer, Ivonne; Ahnert, Peter; Boltze, Johannes; Kirsten, Holger; Friederici, Angela D.; Emmrich, Frank; Brauer, Jens; Neef, Nicole; Skeide, Michael A.; Schaadt, Gesa; Kraft, Indra; Dörr, Liane
Journal Article
2016Bone marrow cell transplantation time-dependently reverses G-CSF effects after stroke in hypertensive rats
Pösel, C.; Wagner, D.C.; Scheibe, J.; Kranz, A.; Bothe, V.; Lange, F.; Schäbitz, W.R.; Minnerup, J.; Boltze, J.
Abstract
2016Challenges and controversies in translational stroke research
Boltze, Johannes; Ayata, Cenk
Journal Article
2016Clumping and viability of bone marrow derived mesenchymal stromal cells under different preparation procedures
Cui, Li-li; Kinnunen, Tuure; Boltze, Johannes; Nystedt, Johanna; Jolkkonen, Jukka
Journal Article
2016The current state of cell therapies for cerebrovascular diseases. Editorial
Jolkkonen, J.; Mendez-Otero, R.; Freitas, G.R. de; Boltze, J.; Rosado-De-Castro, P.H.
Journal Article
2016Focal cerebral ischemia by permanent middle cerebral artery occlusion in sheep
Nitzsche, Björn; Barthel, Henryk; Lobsien, Donald; Boltze, Johannes; Zeisig, Vilia; Dreyer, Antje Y.
Book Article
2016Fully automated calculation of image-derived input function in simultaneous PET/MRI in a sheep model
Jochimsen, Thies H.; Zeisig, Vilia; Schulz, Jessica; Werner, Peter; Patt, Marianne; Patt, Jörg; Dreyer, Antje Y.; Boltze, Johannes; Barthel, Henryk; Sabri, Osama; Sattler, Bernhard
Journal Article
2016Genetic engineering of mesenchymal stem cells for improved homing
Nitzsche, Franziska
: Boltze, Johannes (Betreuer)
Dissertation
2016High acceptance of an early dyslexia screening test involving genetic analyses in Germany
Wilcke, Arndt; Müller, Bent; Schaadt, Gesa; Friederici, Angela D.; Emmrich, Frank; Brauer, Jens; Neef, Nicole; Skeide, Michael A.; Kraft, Indra; Czepezauer, Ivonne; Bobovnikov, Nadin; Kirsten, Holger; Boltze, Johannes
Journal Article
2016Improved prediction of complex diseases by common genetic markers
Müller, Bent; Wilcke, Arndt; Boulesteix, Anne-Laure; Brauer, Jens; Passarge, Eberhard; Boltze, Johannes; Kirsten, Holger
Journal Article
2016Isolation and flow cytometric analysis of immune cells from the ischemic mouse brain
Pösel, Claudia; Möller, Karoline; Boltze, Johannes; Wagner, Daniel-Christoph; Weise, Gesa
Journal Article
2016NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school
Skeide, Michael A.; Kraft, Indra; Müller, Bent; Schaadt, Gesa; Neef, Nicole E.; Brauer, Jens; Wilcke, Arndt; Kirsten, Holger; Boltze, Johannes; Friederici, Angela D.
Journal Article
2016Phase III preclinical trials in translational stroke research
Boltze, Johannes; Wagner, Daniel-Christoph; Henninger, Nils; Plesnila, Nikolaus; Ayata, Cenk
Journal Article
2016Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI
Kraft, Indra; Schreiber, Jan; Cafiero, Riccardo; Metere, Riccardo; Schaadt, Gesa; Brauer, Jens; Neef, Nicole E.; Müller, Bent; Kirsten, Holger; Boltze, Johannes; Friederici, Angela D.; Skeide, Michael A.
Journal Article
2016Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats
Kaiser, D.; Weise, G.; Möller, K.; Scheibe, J.; Pösel, C.; Baasch, S.; Gawlitza, M.; Lobsien, D.; Diederich, K.; Minnerup, J.; Kranz, A.; Boltze, J.; Wagner, D.C.
Abstract
2016Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke
Lees, K.R.; Khatri, P.; Alexandrov, A.V.; Bivard, A.; Boltze, J.; Broderick, J.P.; Campbell, B.C.V.; Creighton, F.M.; Fiorella, D.; Furlan, A.J.; Gorelick, P.B.; Hess, D.C.; Kim, W.-K.; Latour, L.L.; Liebeskind, D.S.; Luby, M.; Lyden, P.; Lynch, J.K.; Marshall, R.S.; Menon, B.K.; Muir, K.W.; Palesch, Y.; Peng, H.; Pryor, K.E.; Mocco, J.; Rasmussen, P.; Sacco, R.L.; Schwamm, L.H.; Smith, E.E.; Solberg, Y.; Vagal, A.; Warach, S.; Wechsler, L.R.; Wintermark, M.; Yoo, A.J.; Zander, K.M.
Journal Article
2016Verfahren zur genbasierten Diagnose eines Legasthenierisikos
Wilcke, Arndt; Ahnert, Peter; Kirsten, Holger; Ligges, Carolin; Boltze, Johannes
Patent
2016Verträglichkeit und Effektivität Cyclosporin A-vermittelter Immunsuppression beim Schaf für die xenogene, intrazerebrale Transplantation
Diehl, Rita
: Boltze, Johannes (Gutachter); Mülling, Christoph (Gutachter); Sterner-Kock, Anja (Gutachter)
Dissertation
2015Arterial hypertension aggravates innate immune responses after experimental stroke
Möller, Karoline; Pösel, Claudia; Kranz, Alexander; Schulz, Isabell; Scheibe, Johanna; Didwischus, Nadine; Boltze, Johannes; Weise, Gesa; Wagner, Daniel-Christoph
Journal Article
2015Autologous bone marrow mononuclear cell therapy of ischemic stroke in sheep
Boltze, J.; Dreyer, A.; Zeisig, V.; Lobsien, D.; Gille, U.; Wagner, D.C.; Kirsten, H.; Barthel, H.
Abstract
2015Bone marrow cell transplantation time-dependently reverses G-CSF effects after stroke in hypertensive rats
Pösel, C.; Wagner, D.C.; Scheibe, J.; Kranz, A.; Bothe, V.; Lange, F.; Schäbitz, W.R.; Minnerup, J.; Boltze, J.
Abstract
2015The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity
Cui, Li-li; Kerkelä, Erja; Bakreen, Abdulhameed; Nitzsche, Franziska; Andrzejewska, Anna; Nowakowski, Adam; Janowski, Miroslaw; Walczak, Piotr; Boltze, Johannes; Lukomska, Barbara; Jolkkonen, Jukka
Journal Article
2015Cortical differences in preliterate children at familiar risk of dyslexia are similar to those observed in dyslexic readers
Kraft, Indra; Cafiero, Riccardo; Schaadt, Gesa; Brauer, Jens; Neef, Nicole; Müller, Bent; Kirsten, Holger; Wilcke, Arndt; Boltze, Johannes; Friederici, Angela D.; Skeide, Michael A.
Journal Article
2015The dark side of the force - constraints and complications of cell therapies for stroke
Boltze, Johannes; Arnold, Antje; Walczak, Piotr; Jolkkonen, Jukka; Cui, Li-li; Wagner, Daniel-Christoph
Journal Article
2015Detection and Quantification of β-Amyloid, Pyroglutamyl Aβ, and Tau in Aged Canines
Schmidt, Franziska; Boltze, Johannes; Jäger, Carsten; Hofmann, Sarah; Willems, Nicole; Seeger, Johannes; Härtig, Wolfgang; Stolzing, Alexandra
Journal Article
2015Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children
Skeide, Michael A.; Kirsten, Holger; Kraft, Indra; Schaadt, Gesa; Müller, Bent; Neef, Nicole; Brauer, Jens; Wilcke, Arndt; Emmrich, Frank; Boltze, Johannes; Friederici, Angela D.
Journal Article
2015Granulocyte colony-stimulating factor and bone marrow mononuclear cells for stroke treatment in the aged brain
Buga, Ana Maria; Scheibe, Johanna; Möller, Karoline; Ciobanu, Ovidiu; Pösel, Claudia; Boltze, Johannes; Popa-Wagner, Aurel
Journal Article
2015Infarction of the corpus callosum: A retrospective clinical investigation
Li, Shen; Sun, Xin; Bai, Yu-meng; Qin, Hua-min; Wu, Xiao-mei; Zhang, Xiao; Jolkkonen, Jukka; Boltze, Johannes; Wang, Su-ping
Journal Article
2015Simultaneous PET/MRI in stroke: A case series
Werner, Peter; Saur, Dorothee; Zeisig, Vilia; Ettrich, Barbara; Patt, Marianne; Sattler, Bernhard; Jochimsen, Thies; Lobsien, Donald; Meyer, Philipp M.; Then Bergh, Florian; Dreyer, Antje; Boltze, Johannes; Classen, Joseph; Fritzsch, Dominik; Hoffmann, Karl-Titus; Sabri, Osama; Barthel, Henryk
Journal Article
2015Spontaneous white matter damage, cognitive decline, and neuroinflammation in middle-aged hypertensive rats: An animal model of early stage cerebral small vessel disease
Kaiser, D.; Weise, G.; Möller, K.; Scheibe, J.; Pösel, C.; Baasch, S.; Gawlitza, M.; Lobsien, D.; Diederich, K.; Minnerup, J.; Kranz, A.; Boltze, J.; Wagner, D.C.
Abstract
2015Stem cell-based tissue replacement after stroke
Janowski, Miroslaw; Wagner, Daniel-Christoph; Boltze, Johannes
Journal Article
2015A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes
Nitzsche, Björn; Frey, Stephen; Collins, Louis D.; Seeger, Johannes; Lobsien, Donald; Dreyer, Antje; Kirsten, Holger; Stoffel, Michael H.; Fonov, Vladimir S.; Boltze, Johannes
Journal Article
2015Working-memory endophenotype and dyslexia-associated genetic variant predict dyslexia phenotype
Männel, Claudia; Meyer, Lars; Wilcke, Arndt; Boltze, Johannes; Kirsten, Holger; Friederici, Angela D.
Journal Article
2014Allometric dose retranslation unveiled substantial immunological side effects of granulocyte colony-stimulating factor after stroke
Wagner, Daniel-Christoph; Pösel, Claudia; Schulz, Isabell; Schicht, Gerda; Boltze, Johannes; Lange, Franziska; Scheibe, Johanna; Möller, Karoline; Weise, Gesa
Journal Article
2014Astrocytic mitochondrial membrane hyperpolarization following extended oxygen and glucose deprivation
Korenic, Andrej; Boltze, Johannes; Deten, Alexander; Peters, Myriam; Andjus, Pavle; Radenovic, Lidija
Journal Article
2014Bone marrow cell transplantation time-dependently abolishes efficacy of granulocyte colony-stimulating factor after stroke in hypertensive rats
Pösel, Claudia; Scheibe, Johanna; Kranz, Alexander; Bothe, Viktoria; Quente, Elfi; Fröhlich, Wenke; Lange, Franziska; Schäbitz, Wolf-Rüdiger; Minnerup, Jens; Boltze, Johannes; Wagner, Daniel-Christoph
Journal Article
2014Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats
Minnerup, Jens; Wagner, Daniel-Christoph; Strecker, Jan-Kolja; Pösel, Claudia; Sevimli-Abdis, Sevgi; Schmidt, Antje; Schilling, Matthias; Boltze, Johannes; Diederich, Kai; Schäbitz, Wolf-Rüdiger
Journal Article
2014Continuous adenosine A(2A) receptor antagonism after focal cerebral ischemia in spontaneously hypertensive rats
Fronz, Ulrike; Deten, Alexander; Baumann, Frank; Kranz, Alexander; Weidlich, Sarah; Härtig, Wolfgang; Nieber, Karen; Boltze, Johannes; Wagner, Daniel-Christoph
Journal Article
2014Flow cytometric characterization of brain dendritic cell subsets after murine stroke
Pösel, Claudia; Uri, Anna; Schulz, Isabell; Boltze, Johannes; Weise, Gesa; Wagner, Daniel-Christoph
Journal Article
2014Genetic risk variants for dyslexia on chromosome 18 in a german cohort
Müller, Bent; Ahnert, Peter; Burkhardt, Jana; Brauer, J.; Czepezauer, Ivonne; Quente, Elfi; Boltze, Johannes; Wilcke, Arndt; Kirsten, Holger
Journal Article
2014Granulocyte colony-stimulating factor (G-CSF) treatment in combination with transplantation of bone marrow cells is not superior to G-CSF treatment alone after cortical stroke in spontaneously hypertensive rats
Diederich, Kai; Schmidt, Antje; Beuker, Carolin; Strecker, Jan-Kolja; Wagner, Daniel-Christoph; Boltze, Johannes; Schäbitz, Wolf-Rüdiger; Minnerup, Jens
Journal Article
2014Mesenchymal stromal cells in stroke
Boltze, Johannes; Lukomska, Barbara; Jolkkonen, Jukka
Journal Article
2014Modelling hematological parameters after total body irradiation
Oelkrug, C.; Hilger, N.; Schönfelder, U.; Boltze, J.; Sack, U.; Fricke, C.; Hildebrandt, G.; Keller, T.; Emmrich, F.; Fricke, S.
Journal Article
2014Multimodal approaches for regenerative stroke therapies: Combination of granulocyte colony-stimulating factor with bone marrow mesenchymal stem cells is not superior to G-CSF alone
Balseanu, Adrian Tudor; Buga, Ana Maria; Catalin, Bogdan; Wagner, Daniel-Christoph; Boltze, Johannes; Zagrean, Ana Maria; Reymann, Klaus G.; Schaebitz, Wolf Ruediger; Popa-Wagner, Aurel
Journal Article
2014The ovine cerebral venous system: Comparative anatomy, visualization, and implications for translational research
Hoffmann, Anke; Stoffel, Michael H.; Nitzsche, Björn; Lobsien, Donald; Seeger, Johannes; Schneider, Holm; Boltze, Johannes
Journal Article
2014Preclinical phase III trials in translational stroke research
Boltze, Johannes; Ayata, Cenk; Wagner, Daniel-Christoph; Plesnila, Nikolaus
Journal Article
2014Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: An animal model of early-stage cerebral small vessel disease
Kaiser, Daniel; Weise, Gesa; Möller, Karoline; Scheibe, Johanna; Pösel, Claudia; Baasch, Sebastian; Gawlitza, Matthias; Lobsien, Donald; Diederich, Kai; Minnerup, Jens; Kranz, Alexander; Boltze, Johannes; Wagner, Daniel-Christoph
Journal Article
2014Stem cells as an emerging paradigm in stroke 3
Savitz, S.I.; Cramer, S.C.; Wechsler, L.; Aronowski, J.; Boltze, J.; Borlongan, C.; Case, C.; Chase, T.; Chopp, M.; Carmichael, S.T.; Cramer, S.C.; Duncan, P.; Finklestein, S.; Fischkoff, S.; Guzman, R.; Hess, D.C.; Huang, D.; Hinson, J.; Kautz, S.; Kondziolka, D.; Mays, R.; Misra, V.; Mitsias, P.; Modo, M.; Muir, K.; Savitz, S.I.; Sinden, J.; Snyder, E.; Steinberg, G.; Vahidy, F.; Wechsler, L.; Willing, A.; Wolf, S.; Yankee, E.; Yavagal, D.R.
Journal Article
2014Sterile inflammation after permanent distal MCA occlusion in hypertensive rats
Möller, Karoline; Boltze, Johannes; Pösel, Claudia; Seeger, Johannes; Stahl, Tobias; Wagner, Daniel-Christoph
Journal Article
2014Temporal dynamics of glyoxalase 1 in secondary neuronal injury
Pieroh, Philipp; Koch, Martin; Wagner, Daniel-Christoph; Boltze, Johannes; Ehrlich, Angela; Ghadban, Chalid; Hobusch, Constance; Birkenmeier, Gerd; Dehghani, Faramarz
Journal Article
2014Transient but not permanent benefit of neuronal progenitor cell therapy after traumatic brain injury
Skardelly, Marco; Gaber, Khaled; Burdack, Swen; Scheidt, Franziska; Schuhmann, Martin U.; Hilbig, Heidegard; Meixensberger, Jürgen; Boltze, Johannes
Journal Article
2014Transplantation of cryopreserved human umbilical cord blood mononuclear cells does not induce sustained recovery after experimental stroke in spontaneously hypertensive rats
Weise, Gesa; Lorenz, Marlene; Pösel, Claudia; Riegelsberger, Ute-Maria; Störbeck, Veronika; Kamprad, Manja; Kranz, Alexander; Wagner, Daniel-Christoph; Boltze, Johannes
Journal Article
2013A concerted appeal for international cooperation in preclinical stroke research
Dirnagl, Ulrich; Hakim, Antoine; MacLeod, Malcolm; Fisher, Marc; Howells, David; Alan, Stuart M.; Steinberg, Gary; Planas, Anna; Boltze, Johannes; Savitz, Sean; Iadecola, Costantino; Meairs, Stephen
Journal Article
2013CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia
Lipfert, Jana; Ödemis, Veysel; Wagner, Daniel-Christoph; Boltze, Johannes; Engele, Jürgen
Journal Article
2013Imaging of VSOP labeled stem cells in agarose phantoms with susceptibility weighted and T2* weighted MR imaging at 3T: Determination of the detection limit
Lobsien, Donald; Dreyer, Antje Y.; Stroh, Albrecht; Boltze, Johannes; Hoffmann, Karl-Titus
Journal Article
2013Object-based analysis of astroglial reaction and astrocyte subtype morphology after ischemic brain injury
Wagner, Daniel-Christoph; Scheibe, Johanna; Glocke, Isabelle; Weise, Gesa; Deten, Alexander; Boltze, Johannes; Kranz, Alexander
Journal Article
2013Tracking of autologous VSOP-labeled mesenchymal stem cells in the sheep brain using 3.0 T MRI
Dreyer, A.Y.; Lobsien, D.; Pösel, C.; Hoffmann, K.-T.; Nitzsche, B.; Findeisen, M.; Stroh, A.; Boltze, J.
Book Article
2012Assessment of neuroprotective effects of human umbilical cord blood mononuclear cell subpopulations in vitro and in vivo
Boltze, Johannes; Reich, Doreen M.; Hau, Susann; Reymann, Klaus G.; Strassburger, Maria; Lobsien, Donald; Wagner, Daniel-Christoph; Kamprad, Manja; Stahl, Tobias
Journal Article
2012Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort
Burkhardt, Jana; Kirsten, Holger; Holland, Heidrun; Krupp, Wolfgang; Ligges, Carolin; Quente, Elfi; Boltze, Johannes; Ahnert, Peter; Wilcke, Arndt
Journal Article
2012Association study of a functional genetic variant in KIAA0319 in German dyslexics
Kirsten, Holger; Wilcke, Arndt; Ligges, Carolin; Boltze, Johannes; Ahnert, Peter
Journal Article
2012Changes in T2 relaxation time after stroke reflect clearing processes
Wagner, Daniel-Christoph; Deten, Alexander; Härtig, Wolfgang; Boltze, Johannes; Kranz, Alexander
Journal Article
2012Density gradient centrifugation compromises bone marrow mononuclear cell yield
Pösel, C.; Möller, K.; Fröhlich, W.; Schulz, I.; Boltze, J.; Wagner, D.C.
Journal Article
2012Frameless stereotaxy in sheep - neurosurgical and imaging techniques for translational stroke research
Dreyer, Antje; Stroh, Albrecht; Pösel, Claudia; Findeisen, Matthias; Geymüller, Teresa von; Lobsien, Donald; Nitzsche, Björn; Boltze, Johannes
Book Article
2012Impact of age on the efficacy of bone marrow mononuclear cell transplantation in experimental stroke
Wagner, Daniel-Christoph; Bojko, Mitja; Peters, Myriam; Lorenz, Marlene; Voigt, Cornelia; Kaminski, Alexander; Hasenclever, D.; Scholz, Markus; Kranz, Alexander; Weise, Gesa; Boltze, Johannes
Journal Article
2012Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles
Terpolilli, N.A.; Kim, S.-W.; Thal, S.C.; Kataoka, H.; Zeisig, V.; Nitzsche, B.; Klaesner, B.; Zhu, C.; Schwarzmaier, S.; Meissner, L.; Mamrak, U.; Engel, D.C.; Drzezga, A.; Patel, R.P.; Blomgren, K.; Barthel, H.; Boltze, J.; Kuebler, W.M.; Plesnila, N.
Journal Article
2012Isolation of inflammatory cells from rat brain tissue after stroke
Möller, K.; Stahl, T.; Boltze, J.; Wagner, D.-C.
Journal Article
2012Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research
Boltze, Johannes; Kleinschnitz, Christoph; Reymann, Klaus G.; Reiser, Georg; Wagner, Daniel-Christoph; Kranz, Alexander; Michalski, Dominik
Journal Article
2012Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation
Michalski, Dominik; Heindl, M.; Kacza, Johannes; Laignel, F.; Küppers-Tiedt, L.; Schneider, Dietmar; Grosche, Jens; Boltze, Johannes; Löhr, M.; Hobohm, Carsten; Härtig, Wolfgang
Journal Article
2011Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic
Wagner, D.-C.; Riegelsberger, U.M.; Michalk, S.; Härtig, W.; Kranz, A.; Boltze, J.
Journal Article
2011Defining the ischemic penumbra with [15O]H2O-PET
Zeisig, V.; Becker, G.; Großmann, U.; Geymüller, T. von; Nitzsche, B.; Dreyer, A.; Kluge, M.; Plesnila, N.; Boltze, J.; Sabri, O.; Barthel, H.
Conference Paper
2011Directed neural differentation of mouse embryonic stem cells
Fronz, U.; Stegmaier, N.; Nieber, K.; Boltze, J.; Wagner, D.C.; Deten, A.
Conference Paper
2011Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke
Michalski, Dominik; Pelz, Johann; Weise, Christopher; Kacza, Johannes; Boltze, Johannes; Grosche, Jens; Kamprad, Manja; Schneider, Dietmar; Hobohm, Carsten; Härtig, Wolfgang
Journal Article
2011Histopathological investigation of different MCAO modalities and impact of autologous bone marrow mononuclear cell administration in an ovine stroke model
Boltze, Johannes; Nitzsche, Björn; Geiger, Kathrin D.; Schoon, Heinz-Adolf
Journal Article
2011Imaging genetics of FOXP2 in dyslexia
Wilcke, A.; Ligges, C.; Burkhardt, J.; Alexander, M.; Wolf, C.; Quente, E.; Ahnert, P.; Hoffmann, P.; Becker, A.; Müller-Myhsok, B.; Cichon, S.; Boltze, J.; Kirsten, H.
Journal Article
2011Intravenous human umbilical cord blood transplantation for stroke
Riegelsberger, U.-M.; Deten, A.; Pösel, C.; Zille, M.; Kranz, A.; Boltze, J.; Wagner, D.-C.
Journal Article
2011Investigation of neuroprotective mechanisms using a primary neural in vitro ischemia model
Wielsch, B.; Jaklin, M.; Nitzsche, F.; Boltze, J.; Peters, M.
Conference Paper
2011Long-term benefit of human fetal neuronal progenitor cell transplantation in a clinically adapted model after traumatic brain injury
Skardelly, Marco; Gaber, Khaled; Burdack, Swen; Scheidt, Franziska; Hilbig, Heidegard; Boltze, Johannes; Förschler, Annette; Schwarz, Johannes; Schwarz, Sigrid; Schuhmann, Martin U.; Meixenberger, Jürgen
Journal Article
2011Neurobiological and clinical aspects of cell therapies for ischemic stroke
Boltze, Johannes
Dissertation
2011Recent advances in basic and translational stroke research
Boltze, J.; Kranz, A.; Wagner, D.-C.; Reymann, K.; Reiser, G.; Hess, D.C.
Journal Article, Conference Paper
2011Regenerative Therapien für Kinderherzen
Yerebakan, C.; Niefeldt, S.; Klopsch, C.; Prietz, S.; Rebl, A.; Goldammer, T.; Boltze, J.; Sandica, E.; Steinhoff, G.
Journal Article
2011Towards a genetic screening test for dyslexia allowing functional regeneration
Kirsten, H.; Wilcke, A.; Burkhardt, J.; Quente, E.; Ligges, C.; Scholz, M.; Klopp, N.; Illig, T.; Mielck, A.; Ahnert, P.; Boltze, J.
Conference Paper
2010Analysis of GFAP expression after stroke in bone marrow cell treated sheep by two evaluation methods
Geymüller, T. von; Hoffmann, A.; Schoon, H.-A.; Seeger, J.; Boltze, J.; Nitzsche, B.
Abstract
2010Autologous bone marrow cell therapy of stroke in an ovine model
Boltze, J.; Forschler, A.; Nitzsche, B.; Dreyer, A.; Zeisig, V.; Geymuller, T. von
Abstract
2010Characterization of murine non-adherent bone marrow cells leading to recovery of endogenous hematopoiesis
Fricke, Stephan; Fricke, Christian; Oelkrug, Christopher; Hilger, Nadja; Schönfelder, Uta; Kamprad, Manja; Lehmann, Jörg; Boltze, Johannes; Emmrich, Frank; Sack, Ulrich
Journal Article
2010Differentiation of neuron-like cells from rat fibroblastderived induced pluripotent stem cells in vitro
Fronz, U.; Fröhlich, W.; Arnold, A.; Stolzing, A.; Nieber, K.; Boltze, J.; Wagner, D.C.; Deten, A.
Abstract
2010Evaluation of neuroprotective properties of a continuously administered A2A receptor antagonist in a rodent stroke model
Fronz, U.; Weidlich, S.; Kranz, A.; Nieber, K.; Boltze, J.; Wagner, D.-C.
Conference Paper, Poster
2010Evaluierung anti-apoptotischer Effekte von 8-(3-Chlorostyryl)-Coffein nach fokaler zerebraler Ischämie
Weidlich, Sarah
: Nieber, Karen (Gutachter); Boltze, Johannes (Gutachter)
Thesis
2010Genetische Grundlagen der Legasthenie
Wilcke, A.; Boltze, J.
Book Article
2010Imaging genetics of FOXP2 in dyslexia
Ahnert, P.; Boltze, J.; Ligges, C.; Kirsten, H.; Wilcke, A.; Burkhardt, J.; Quente, E.
Abstract
2010New targets for stroke therapy - an in vitro approach
Wielsch, B.; Nitzsche, F.; Boltze, J.; Müller, M.
Abstract
2010No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers
Mühle, Anja; Mühle, Christiane; Amann, Kerstin; Dötsch, Jörg; Nüsken, Kai-Dietrich; Boltze, Johannes; Schneider, Holm
Journal Article
2010Syngeneic transplantation of adipose tissue-derived cells for experimental stroke
Taubert, J.; Safdari, S.; Pösel, C.; Kranz, A.; Scheibe, J.; Boltze, J.; Wagner, D.-C.
Abstract
2010Towards a genetic screening test for dyslexia allowing functional regeneration: a strategy for identification and analysis of genetic risk factors
Holger, K.; Wilke, A.; Ahnert, P.; Boltze, J.
Abstract
2010Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats
Kranz, A.; Wagner, D.-C.; Kamprad, M.; Scholz, M.; Schmidt, U.R.; Nitzsche, F.; Aberman, Z.; Emmrich, F.; Riegelsberger, U.-M.; Boltze, J.
Journal Article
2010Validation of neurofunctional tests for stroke in spontaneously hypertensive rats
Kranz, A.; Braun, S.; Okoniewski, J.; Boltze, J.; Wagner, D.-C.
Abstract
2009[F-18]Feta PET-a new method for hot spot imaging of the ischemic penumbra in acute stroke
Barthel, H.; Grossmann, U.; Zeisig, V.; Patt, M.; Wagner, D.; Patt, J.; Kluge, M.; Franke, H.; Sorger, D.; Luthardt, J.; Nitzsche, B.; Dreyer, A.; Brust, P.; Steinbach, J.; Boltze, J.; Emmrich, F.; Sabri, O.
Abstract
2009Acute and chronic response of the right ventricle to surgically induced volume and pressure overload
Yerebakan, C.; Klopsch, C.; Prietz, S.; Niefeldt, S.; Gabel, R.; Kaminski, A.; Boltze, J.; Vollmar, B.; Ma, N.; Sandica, E.; Liebold, A.; Steinhoff, G.
Conference Paper, Journal Article
2009Allogeneic non-adherent bone marrow cells do not lead to allogeneic engraftment but facilitate hematopoietic recovery
Sack, U.; Ackermann, M.; Stolzing, A.; Hilger, N.; Schimmelpfennig, C.; Jahns, J.; Hildebrandt, G.; Emmrich, F.; Boltze, J.; Kamprad, M.; Fricke, S.
Abstract
2009Autologous bone marrow cell administration 24 h following MCAO reduces behavioral deficits and lesion size in a novel large animal model
Boltze, J.; Förschler, A.; Barthel, H.; Nitzsche, B.; Dreyer, A.; Zeisig, V.; Geymüller, T. von; Boltze, C.; Sabri, O.; Lobsien, D.; Hoffmann, A.; Reischauer, A.; Emmrich, F.; Gille, U.
Abstract
2009Autologous Umbilical Cord Blood Mononuclear Cell Transplantation Preserves Right Ventricular Function in a Novel Model of Chronic Right Ventricular Volume Overload
Yerebakan, C.; Sandica, E.; Prietz, S.; Klopsch, C.; Ugurlucan, M.; Kaminski, A.; Abdija, S.; Lorenzen, B.; Boltze, J.; Nitzsche, B.; Egger, D.; Barten, M.; Furlani, D.; Ma, N.; Vollmar, B.; Liebold, A.; Steinhoff, G.
Journal Article
2009Impact of cell therapies on post-ischemic astrogliosis
Wagner, D.C.; Kranz, A.; Riegelsberger, U.M.; Poesel, C.; Emmrich, F.; Boltze, J.
Abstract
2009Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of parkinson disease
Stroh, A.; Boltze, J.; Sieland, K.; Hild, K.; Gutzeit, C.; Jung, T.; Kressel, J.; Hau, S.; Reich, D.; Grune, T.; Zimmer, C.
Journal Article
2009Influence of donor and recipient age on bone marrow mononuclear cell treatment after experimental stroke
Bojko, M.; Lorenz, M.; Voigt, C.; Kranz, A.; Kamprad, M.; Emmrich, F.; Boltze, J.; Wagner, D.-C.
Abstract
2009Intramyocardial injection of erythropoietin enhances right ventricular diastolic performance after surgically induced pressure overload
Yerebakan, C.; Klopsch, C.; Prietz, S.; Niefeldt, S.; Gabel, R.; Kaminski, A.; Boltze, J.; Vollmar, B.; Ma, N.; Sandica, E.; Liebold, A.; Steinhoff, G.
Conference Paper, Journal Article
2009Intravenous administration of human umbilical cord blood cells did not reduce infarct volume and caspase-3-dependent apoptosis
Kranz, A.; Riegelsberger, U.M.; Poesel, C.; Boltze, J.; Emmrich, F.; Wagner, D.C.
Abstract
2009Multimodal evaluation of the neuroprotective potential of CSC in a rodent model of focal cerebral ischemia
Fronz, Ulrike
: Nieber, Karen (Supervisor); Boltze, Johannes (Supervisor)
Thesis
2009Pressure-volume loops
Yerebakan, C.; Klopsch, C.; Prietz, S.; Boltze, J.; Vollmar, B.; Liebold, A.; Steinhoff, G.; Sandica, E.
Conference Paper, Journal Article
2009Pressure-volume loops: feasible for the evaluation of right ventricular function in an experimental model of acute pulmonary regurgitation?
Yerebakan, C.; Klopsch, C.; Prietz, S.; Boltze, J.; Vollmar, B.; Liebold, A.; Steinhoff, G.; Sandica, E.
Journal Article
2009The role of gene DCDC2 in German dyslexics
Wilcke, Arndt; Weissfuss, J.; Kirsten, H.; Wolfram, G.; Boltze, Johannes; Ahnert, P.; Kirsten, H.
Journal Article
2009Stem cell therapies as an emerging paradigm in stroke (STEPS)
Wechsler, Lawrence; Steindler, Dennis; Borlongan, Cesar; Chopp, Michael; Savitz, Sean; Deans, Robert; Caplan, Louis; Hess, David; Mays, Robert W.; Boltze, Johannes; et. Al
Journal Article
2009Triple fluorescence labelling of neuronal, glial and vascular markers revealing pathological alterations in various animal models
Härtig, Wolfgang; Reichenbach, Andreas; Voigt, Cornelia; Boltze, Johannes; Bulavina, Larysa; Schuhmann, Martin U.; Seeger, Johannes; Schusser, Gerald Fritz; Freytag, Christiane; Grosche, Jens
Journal Article
2008Cord blood cell therapy alters LV remodeling and cytokine expression but does not improve heart function after Myocardial infarction in rats
Rabald, S.; Marx, G.; Mix, B.; Stephani, C.; Kamprad, M.; Cross, M.; Boltze, J.; Briest, W.; Zimmer, H.G.; Deten, A.
Journal Article
2008Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro
Hau, S.; Reich, D.M.; Scholz, M.; Naumann, W.; Emmrich, F.; Kamprad, M.; Boltze, J.
Journal Article
2008Experimentelle Zelltherapie des ischämischen Schlaganfalls unter Nutzung stammzellhaltiger Populationen des humanen Nabelschnurbluts in der Ratte
Boltze, Johannes
Dissertation
2008Neuronal hypoxia in vitro: Investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells
Reich, Doreen M.; Hau, Susann; Stahl, Tobias; Scholz, Markus; Naumann, Wilfried; Emmrich, Frank; Boltze, Johannes; Kamprad, Manja
Journal Article
2008Permanent middle cerebral artery occlusion in sheep
Boltze, Johannes; Förschler, Annette; Nitzsche, Björn; Waldmin, Daniela; Hoffmann, Anke; Boltze, Chistiane M.; Dreyer, Antje Y.; Goldammer, Axel; Reischauer, Anne; Härtig, Wolfgang; Geiger, Kathrin D.; Barthel, Henryk; Emmrich, Frank; Gille, Uwe
Journal Article
2007Brain perfusion and glucose consumption PET to monitor stem cell effects on stroke outcome in a new large animal model - A feasibiliy study
Barthel, H.; Boltze, J.; Forschler, A.; Grossmann, U.; Schildan, A.; Boltze, C.; Gille, U.; Patt, M.; Seese, A.; Becker, G.; Emmrich, F.; Sabri, O.
Abstract
2007Cell therapy of stroke in small and large animals
Boltze, J.; Förschler, A.; Schmidt, U.R.; Wagner, D.C.; Schwarz, D.C.; Boltze, C.M.; Bulawina, L.; Lang, A.B.; Sabri, O.; Barthel, H.; Emmrich, F.; Gille, U.
Journal Article
2007A feasibility study on quantitative [15O]H2O and [18F]FDG brain PET in a new large-animal stroke model in sheep
Barthel, H.; Boltze, J.; Grossmann, U.; Schildan, A.; Förschler, A.; Gille, U.; Patt, M.; Seese, A.; Emmrich, F.; Sabri, O.
Journal Article
2007MR-Bildgebung eines experimentellen Schlaganfallmodells beim Schaf
Förschler, Annette; Boltze, Johannes; Waldmin, Daniela; Gille, Uwe; Zimmer, Claus
Journal Article
2007Permanent MCAO in sheep - A novel model of focal cerebral ischemia
Boltze, J.; Förschler, A.; Barthel, H.; Lang, A.B.; Boltze, C.M.; Sabri, O.; Emmrich, F.; Gille, U.
Journal Article
2006Intravenous versus intrastriatal transplantation of human fetal neural stem cells in experimental stroke - A comparison of lesion development and sensomotoric benefits.
Wagner, D.; Schwarz, S.; Schmidt, U.; Forschler, A.; Lobsien, D.; Faber, S.; Kamprad, M.; Emmrich, F.; Boltze, J.
Abstract
2006The stairway: A novel behavioral test detecting sensomotoric stroke deficits in rats
Boltze, Johannes; Kowalski, Ina; Förschler, Annette; Schmidt, Uwe; Wagner, Daniel; Lobsien, Donald; Emmrich, Julius; Egger, Dietmar; Kamprad, Manja; Blunk, James; Emmrich, Frank
Journal Article
2006Therapeutic time frame for sensorimotoric recovery
Schmidt, U.; Wagner, D.; Förschler, A.; Lobsien, D.; Faber, S.; Kamprad, M.; Emmrich, F.; Boltze, J.
Abstract
2005Behavioural improvement, reactive gliosis and lesioned area in rodent model of cerebral ischemia following stem cell treatment
Bulawina, L.; Boltze, J.; Kamprad, M.; Hartig, W.; Paulke, B.R.; Grosche, J.; Arendt, T.; Emmrich, F.
Abstract
2005Experimental treatment of stroke in spontaneously hypertensive rats by CD34+ and CD34- cord blood cells
Boltze, J.; Kowalski, I.; Geiger, K.; Reich, D.; Albrecht, G.; Buhrle, C.; Egger, D.; Kamprad, M.; Emmrich, F.
Journal Article