Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2016Inhalation TTC values: A new integrative grouping approach considering structural, toxicological and mechanistic features
Tluczkiewicz, Inga; Kühne, Ralph; Ebert, Ralf-Uwe; Batke, Monika; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia E.
Journal Article
2016Innovative strategies to develop chemical categories using a combination of structural and toxicological properties
Batke, Monika; Gütlein, Martin; Partosch, Falko; Gundert-Remy, Ursula; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Seeland, Madeleine; Bitsch, Annette
Journal Article
2015Development of chemical categories by optimized clustering strategies
Bitsch, Annette; Batke, Monika; Gundert-Remy, U.; Gütlein, M.; Kramer, S.; Partosch, F.; Seeland, M.
Abstract
2015Optimization of curation of the dataset with data on repeated dose toxicity
Gundert-Remy, Ursula; Batke, Monika; Bitsch, Annette; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine
Abstract
2015Support for the use of computer-based predictions like quantitative structure-activity relationships (QSAR methods) to avoid animal testing under REACH
Escher, Sylvia; Batke, Monika; Arning, Jürgen; Brandt, Marc; Kupper, Jürgen; Eifert, Harald; Wibbertmann, Axel
Abstract
2014Analysing reproductive toxicity studies using the FeDTex database - does an F2-generation provide an additional benefit?
Schulz, Florian; Lewin, Geertje; Mangelsdorf, Inge; Batke, Monika; Escher, Sylvia
Journal Article, Conference Paper
2014Correlations between different endpoints in repeated dose toxicity studies: Occurrence of dependent and independent effects at equal dose levels in the RepDose and the "ELINCS" database
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Kramer, Stefan; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Journal Article, Conference Paper
2014Development of an in silico pre-screen for reproductive toxicity within the EU project ChemScreen
Lewin, Geertje; Burg, Bart van der; Batke, Monika; Escher, Sylvia; Mangelsdorf, Inge
Journal Article, Conference Paper
2014Development of chemical categories by optimized clustering strategies
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Journal Article, Conference Paper
2014Incorporating potency into EU classification for carcinogenicity and reproductive toxicity
Hennes, C.; Batke, Monika; Bomann, W.; DuHayon, S.; Kosemund, K.; Politano, V.; Stinchcombe, S.; Doe, J.
Journal Article
2014Multi-Label-Classification to predict repeated dose toxicity in the context of REACH
Batke, Monika; Bitsch, Annette; Gundert-Remy, Ursula; Gütlein, Martin; Helma, Christoph; Kramer, Stefan; Maunz, Andreas; Partosch, Falko; Seeland, Madeleine; Stahlmann, Ralf
Journal Article, Conference Paper
2014Sensitivity of different generations and developmental stagesin studies on reproductive toxicity
Schulz, Florian; Batke, Monika; Mangelsdorf, Inge; Pohlenz-Michel, Christina; Simetska, Nelly; Lewin, Geertje
Journal Article
2014TTC: A new concept for inhalation exposure
Tluczkiewicz, Inga; Batke, Monika; Kühne, Ralph; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia
Journal Article, Conference Paper
2014TTC: A new concept for inhalation exposure
Escher, Sylvia; Tluczkiewicz, Inga; Batke, Monika; Kühne, Ralf; Ebert, Ralf-Uwe; Schüürmann, Gerrit; Mangelsdorf, Inge
Abstract
2013Analysis of the indicative value of repeated dose toxicity studies for reproductive toxicity
Lewin, Geertje; Batke, Monika; Escher, Sylvia; Mangelsdorf, Inge
Journal Article, Conference Paper
2013Assessment factors in human health risk assessment and their associated level of safety
Escher, Sylvia; Hoffmann-Doerr, S.; Batke, Monika; Mangelsdorf, Inge
Journal Article, Conference Paper
2013FeDTex database - a versatile tool condensing data from developmental and reproductive toxicity studies
Schulz, Florian; Batke, Monika; Lewin, Geertje; Escher, Sylvia; Mangelsdorf, Inge
Journal Article, Conference Paper
2013New strategies for the generation of chemical categories under REACH
Batke, Monika; Gundert-Remy, U.; Helma, C.; Kramer, S.; Kleppe-Nordqvist, Sara; Maunz, A.; Partosch, F.; Seeland, M.; Bitsch, Annette
Journal Article, Conference Paper
2013The OSIRIS weight of evidence approach: ITS for the endpoints repeated-dose toxicity (RepDose ITS)
Tluczkiewicz, Inga; Batke, Monika; Kroese, Dinant; Buist, Harrie; Aldenberg, Tom; Pauné, Eduard; Grimm, Helvi; Kühne, Ralph; Schüürmann, Gerrit; Mangelsdorf, Inge; Escher, Sylvia E.
Journal Article
2013The OSIRIS weight of evidence approach: ITS mutagenicity and ITS carcinogenicity
Buist, Harrie; Aldenberg, Tom; Batke, Monika; Escher, Sylvia; Klein, Entink R.; Kühne, Ralph; Marquart, Hans; Pauné, Eduard; Rorije, Emiel; Schüürmann, Gerrit; Kroese, Dinant
Journal Article
2013Relevance of non-guideline studies for risk assessment. The coverage model based on most frequent targets in repeated dose toxicity studies
Batke, Monika; Aldenberg, Tom; Escher, Sylvia; Mangelsdorf, Inge
Journal Article
2012Derived values and databases for non-cancer endpoints: Considerations and concerns
Tluczkiewicz, Inga; Batke, Monika; Mangelsdorf, Inge; Escher, Sylvia
Journal Article, Conference Paper
2012OpenTox predictive toxicology framework
Tcheremenskaia, Olga; Benigni, Romualdo; Nikolova, Ivelina; Jeliazkova, Nina; Escher, Sylvia E.; Batke, Monika; Baier, Thomas; Poroikov, Vladimir; Lagunin, Alexey; Rautenberg, Micha; Hardy, Barry
Journal Article