Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019Challenging the dose-response-time data approach
Andersson, R.; Jirstrand, M.; Almquist, J.; Gabrielsson, J.
Journal Article
2018Evaluation and translation of combination therapies in oncology
Cardilin, T.; Almquist, J.; Jirstrand, M.; Gabrielsson, J.
Journal Article
2018Exact Gradients Improve Parameter Estimation in Nonlinear Mixed Effects Models with Stochastic Dynamics
Olafsdottir, H.K.; Leander, J.; Almquist, J.; Jirstrand, M.
Journal Article
2018Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists
Almquist, J.; Hovdal, D.; Ahlström, C.; Fjellström, O.; Gennemark, P.; Sundqvist, M.
Journal Article
2017Erratum to: Tumor Static Concentration Curves in Combination Therapy
Cardilin, T.; Almquist, J.; Jirstand, M.; Soselly, A.; Amendt, C.; El Bawab, S.; Gabrielsson, J.
Journal Article
2017Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin
Pehrsson, S.; Johansson, K.J.; Janefeldt, A.; Sandinge, A.S.; Maqbool, S.; Goodman, J.; Sanchez, J.; Almquist, J.; Gennemark, P.; Nylander, S.
Journal Article
2017Modeling of free fatty acid dynamics: Insulin and nicotinic acid resistance under acute and chronic treatments
Andersson, R.; Kroon, T.; Almquist, J.; Jirstrand, M.; Oakes, N.D.; Evans, N.D.; Chappel, M.J.; Gabrielsson, J.
Journal Article
2017Tumor static concentration curves in combination therapy
Cardilin, T.; Almquist, J.; Jirstrand, M.; Sostelly, A.; Amendt, C.; El Bawab, S.; Gabrielsson, J.
Journal Article
2016Unraveling the pharmacokinetic interaction of ticagrelor and MEDI2452 (Ticagrelor antidote) by mathematical modeling
Almquist, J.; Penney, M.; Pehrsson, S.; Sandinge, A.-S.; Janefeldt, A.; Maqbool, S.; Madalli, S.; Goodman, J.; Nylander, S.; Gennemark, P.
Journal Article
2015Mixed effects modeling using stochastic differential equations: Illustrated by pharmacokinetic data of nicotinic acid in obese zucker rats
Leander, J.; Almquist, J.; Ahlström, C.; Gabrielsson, J.; Jirstrand, M.
Journal Article
2015A nonlinear mixed effects approach for modeling the cell-to-cell variability of Mig1 dynamics in yeast
Almquist, J.; Bendrioua, L.; Adiels, C.B.; Goksör, M.; Hohmann, S.; Jirstrand, M.
Journal Article
2015Using sensitivity equations for computing gradients of the FOCE and FOCEI approximations to the population likelihood
Almquist, J.; Leander, J.; Jirstrand, M.
Journal Article
2014Bridging the gaps in systems biology
Cvijovic, M.; Almquist, J.; Hagmar, J.; Hohmann, S.; Kaltenbach, H.-M.; Klipp, E.; Krantz, M.; Mendes, P.; Nelander, S.; Nielsen, J.; Pagnani, A.; Przulj, N.; Raue, A.; Stelling, J.; Stoma, S.; Tobin, F.; Wodke, J.A.H.; Zecchina, R.; Jirstrand, M.
Journal Article
2014Joint feedback analysis modeling of nonesterified fatty acids in obese zucker rats and normal sprague-dawley rats after different routes of administration of nicotinic acid
Tapani, S.; Almquist, J.; Leander, J.; Ahlström, C.; Peletier, L.A.; Jirstrand, M.; Gabrielsson, J.
Journal Article
2014Kinetic models in industrial biotechnology - improving cell factory performance
Almquist, J.; Cvijovic, M.; Hatzimanikatis, V.; Nielsen, J.; Jirstrand, M.
Journal Article
2014Yeast AMP-activated protein kinase monitors glucose concentration changes and absolute glucose levels
Bendrioua, L.; Smedh, M.; Almquist, J.; Cvijovic, M.; Jirstrand, M.; Goksör, M.; Adiels, C.B.; Hohmann, S.
Journal Article
2010A kinetic model of the monocarboxylate transporter MCT1 and its interaction with carbonic anhydrase II
Almquist, J.; Lang, P.; Prätzel-Wolters, D.; Deitmer, J.; Jirstrand, M.; Becker, H.
Journal Article
2010Modeling the effect of Kv1.5 block on the canine action potential
Almquist, J.; Wallman, M.; Jacobson, I.; Jirstrand, M.
Journal Article
2008Determination of interaction between MCT1 and CAII via a mathematical and physiological approach
Almquist, J.; Schmidt, H.; Lang, P.; Deitmer, J.; Jirstrand, M.; Prätzel-Wolters, D.; Becker, H.